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Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2014, Volume 289, Issue 5, pp. 2687 - 2700
Background: IL-8 promotes angiogenesis and metastasis in ovarian cancer. Results: Proteasome inhibition induces specific recruitment of IKK, EGR-1, and... 
Transcription Regulation | PROTEIN | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | Egr-1 | ALPHA | DRUG-RESISTANCE | BORTEZOMIB | NF-B (NF-KB) | Interleukin-8 | INDEPENDENT PROSTATE-CANCER | NUCLEAR TRANSLOCATION | Ovarian Cancer | P65 SUBUNIT | Immunology | GENE-EXPRESSION | GROWTH-FACTOR | Chemokines | Chromatin Immunoprecipitation (ChIP) | Proteasome | Interleukin-8 - genetics | Promoter Regions, Genetic - radiation effects | Humans | Ovarian Neoplasms - pathology | Multiple Myeloma - immunology | Chemokine CXCL5 - metabolism | Promoter Regions, Genetic - drug effects | Cell Nucleus - metabolism | I-kappa B Kinase - metabolism | Female | Antineoplastic Agents - pharmacology | Chemokine CCL2 - metabolism | Ovarian Neoplasms - metabolism | Interleukin-8 - metabolism | Bortezomib | Proteasome Inhibitors - pharmacology | Gene Expression Regulation, Leukemic - drug effects | Chemokine CCL2 - genetics | Multiple Myeloma - metabolism | Chemokine CXCL5 - genetics | Multiple Myeloma - pathology | Transcription Factor RelA - metabolism | Cell Line, Tumor | Promoter Regions, Genetic - immunology | Proteasome Endopeptidase Complex - metabolism | Pyrazines - pharmacology | Early Growth Response Protein 1 - metabolism | Boronic Acids - pharmacology | Gene Expression Regulation, Leukemic - immunology | Ovarian Neoplasms - immunology | NF-κB (NF-KB)
Journal Article
Journal Article
Aging, ISSN 1945-4589, 04/2009, Volume 1, Issue 4, pp. 402 - 411
Senescence is a cellular program that irreversibly arrests the proliferation of damaged cells and induces the secretion of the inflammatory mediators IL- 6 and... 
DNA damage | HUMAN-CELLS | IL-1 alpha | TUMOR-SUPPRESSOR NETWORK | IL-8 | CELLULAR SENESCENCE | CANCER | IL-6 | P53 | CELL BIOLOGY | inflammation | GROWTH | miRNA | DIFFERENTIATION | STRESS | EXPRESSION | IMMORTALIZATION
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2010, Volume 120, Issue 12, pp. 4236 - 4250
Journal Article
International Journal of Oncology, ISSN 1019-6439, 01/2016, Volume 48, Issue 1, pp. 5 - 12
The epithelial-mesenchymal transition (EMT) is a process through which epithelial cells trans-differentiate and acquire an aggressive mesenchymal phenotype. In... 
Paracrine | Epithelial-mesenchymal transition | Autocrine | IL-8 | Signal pathways | CARCINOMA-CELLS | TGF-BETA | paracrine | signal pathways | FACTOR-KAPPA-B | OVARIAN-CANCER | INDEPENDENT PROSTATE-CANCER | BREAST-CANCER CELLS | HEPATOCELLULAR-CARCINOMA | NASOPHARYNGEAL CARCINOMA | ONCOLOGY | epithelial-mesenchymal transition | autocrine | PROMOTES INVASION
Journal Article
Scientific Reports, ISSN 2045-2322, 08/2016, Volume 6, Issue 1, p. 32188
Complex interactions exist between cytokines, and the interleukin family plays a fundamental role in inflammation. Particularly circulating IL-1 beta, IL-6 and... 
INDUCED SUICIDAL DEATH | LIFE-SPAN | COAGULATION KINETICS | IFN-GAMMA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | SERUM-LEVELS | FACTOR-XIII | NECROSIS-FACTOR-ALPHA | SOLUBLE IL-6 | TNF-ALPHA | Interleukin-1beta - pharmacology | Interleukin-6 - pharmacology | Blood Viscosity | Humans | Blood Coagulation | Elasticity | Female | Interleukin-8 - pharmacology | Male
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 11/2003, Volume 278, Issue 46, pp. 45777 - 45784
Several studies have shown a relationship between interleukin (IL) 6 levels and insulin resistance. We here show that human subcutaneous adipose cells, like... 
HUMAN ADIPOSE-TISSUE | OBESITY | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | WEIGHT-LOSS | SENSITIVITY | RECEPTOR | GLUCOSE-TRANSPORT | TNF-ALPHA | TYPE-2 DIABETES-MELLITUS | EXPRESSION | Tumor Necrosis Factor-alpha - metabolism | Up-Regulation | Phosphorylation | Humans | Middle Aged | Repressor Proteins | Phosphoproteins - metabolism | RNA, Messenger - metabolism | Suppressor of Cytokine Signaling Proteins | Dose-Response Relationship, Drug | Adipose Tissue - metabolism | Mitogen-Activated Protein Kinase Kinases - metabolism | Muscle Proteins | MAP Kinase Kinase 4 | Biological Transport | Time Factors | Insulin Receptor Substrate Proteins | JNK Mitogen-Activated Protein Kinases | Adult | Transcription, Genetic | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Monosaccharide Transport Proteins - metabolism | Tyrosine - chemistry | RNA - metabolism | Cytokines - metabolism | Glucose Transporter Type 4 | Insulin Resistance | 3T3-L1 Cells | Reverse Transcriptase Polymerase Chain Reaction | Suppressor of Cytokine Signaling 3 Protein | Blotting, Northern | Tyrosine - metabolism | Animals | Proteins - metabolism | Adipocytes - metabolism | Glucose - metabolism | Mice | Transcription Factors | insulin receptors | pS-307 protein | peroxisome proliferator-activated receptors | IRS-1 protein | GLUT-4 protein | JNK protein | insulin-receptor substrate 2 | insulin resistance | glucose transporter GLUT4 | insulin-receptor substrate 1 protein
Journal Article