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Journal Article
Arthritis research & therapy, ISSN 1478-6354, 2013, Volume 15, Issue 5, pp. R151 - R151
Introduction: T helper (Th)-17 cells are increased in systemic sclerosis (SSc). We therefore assessed whether Th17 cells could modulate the inflammatory and... 
RHEUMATOID-ARTHRITIS | MATRIX METALLOPROTEINASES | SYNOVIAL FIBROBLASTS | MONOCYTE CHEMOATTRACTANT PROTEIN-1 | GENE-EXPRESSION | SKIN FIBROSIS | NECROSIS-FACTOR-ALPHA | RHEUMATOLOGY | NF-KAPPA-B | T-CELLS | PULMONARY-FIBROSIS | Interleukin-8 - genetics | Gene Expression - drug effects | Skin - metabolism | Humans | Scleroderma, Systemic - pathology | Culture Media, Conditioned - pharmacology | Male | Interleukin-17 - pharmacology | Dose-Response Relationship, Drug | Collagen Type I - genetics | Th17 Cells - metabolism | Radioimmunoassay | Inflammation Mediators - metabolism | Female | Chemokine CCL2 - metabolism | Interleukin-8 - metabolism | Matrix Metalloproteinase 1 - genetics | Skin - pathology | Fibroblasts - metabolism | Collagen Type I - metabolism | Enzyme-Linked Immunosorbent Assay | Scleroderma, Systemic - metabolism | Cells, Cultured | Scleroderma, Systemic - genetics | Chemokine CCL2 - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Tumor Necrosis Factor-alpha - pharmacology | Fibroblasts - drug effects | Matrix Metalloproteinase 1 - metabolism | Interferon-gamma - pharmacology | Culture Media, Conditioned - metabolism | Proteins | Medical equipment and supplies industry | Interleukins | Systemic scleroderma | Medical test kit industry | Scleroderma (Disease) | High-definition television | Skin | Biological response modifiers | Enzyme-linked immunosorbent assay
Journal Article
Inflammation research, ISSN 1023-3830, 02/2018, Volume 67, Issue 2, pp. 169 - 177
OBJECTIVE: To investigate the ex vivo pro-inflammatory properties of classical and non-classical monocytes as well as myeloid dendritic cells (mDCs) in... 
Dendrites/metabolism | Humans | Middle Aged | Male | Journal Article | Interleukin-8/metabolism | Immunology | Adult | Female | Classical monocytes | Interferons/metabolism | Pulmonary Fibrosis/metabolism | Myeloid dendritic cells | Inflammation | Sialic Acid Binding Ig-like Lectin 1/metabolism | Pharmacology | Non-classical monocytes | Scleroderma, Systemic/metabolism | Chemokine CCL4/metabolism | Systemic sclerosis | Toll-Like Receptor 4/metabolism | Aged | Myeloid Cells/metabolism | Chemokines | Cytokines/biosynthesis | Chemokine CXCL10/metabolism | Monocytes/metabolism | Dermatology | Rheumatology | Allergology | Neurology | Biomedicine | Pharmacology/Toxicology | BRONCHOALVEOLAR LAVAGE FLUID | SUBSETS | CYTOKINE | IMMUNOLOGY | CELL BIOLOGY | INTERSTITIAL LUNG-DISEASE | PATHOGENESIS | SCLERODERMA | GENE-EXPRESSION | CHEMOKINE FAMILY | RECEPTORS | PULMONARY-FIBROSIS | Dendrites - metabolism | Scleroderma, Systemic - metabolism | Monocytes - metabolism | Toll-Like Receptor 4 - metabolism | Sialic Acid Binding Ig-like Lectin 1 - metabolism | Interferons - metabolism | Myeloid Cells - metabolism | Chemokine CCL4 - metabolism | Pulmonary Fibrosis - metabolism | Interleukin-8 - metabolism | Chemokine CXCL10 - metabolism | Cytokines - biosynthesis | Interferon | Systemic scleroderma | Dendritic cells | Biological response modifiers | Analysis | Scleroderma (Disease) | Cluster analysis | Flow cytometry | Respiratory function | Carbon tetrachloride | Stimulation | Parameter identification | Interleukin 6 | Proteins | Peripheral blood | Toll-like receptors | Immune system | Cytokines | Lung diseases | Clustering | Patients | Cytometry | Monocytes | Production methods | γ-Interferon | CXCL10 protein | Fibrosis | Pulmonary functions | Original Research Paper
Journal Article
Blood, ISSN 0006-4971, 02/2009, Volume 113, Issue 7, pp. 1526 - 1534
Journal Article
Clinical and experimental immunology, ISSN 0009-9104, 2010, Volume 162, Issue 1, pp. 100 - 107
Summary Pyoderma gangrenosum (PG) is a rare, immune‐mediated inflammatory skin disease presenting with painful ulcers having undermined edges. Less commonly,... 
cytokines | pyoderma gangrenosum | matrix metalloproteinases | neutrophilic dermatoses | Sweet's syndrome | INTERLEUKIN-17 | PYODERMA-GANGRENOSUM | SWEETS-SYNDROME | NECROSIS-FACTOR-ALPHA | IMMUNOLOGY | EXPRESSION | Immunohistochemistry | Tumor Necrosis Factor-alpha - metabolism | Humans | Middle Aged | Male | Vascular Endothelial Growth Factor A - metabolism | Antigens, CD - metabolism | Young Adult | Matrix Metalloproteinase 9 - metabolism | Sweet Syndrome - metabolism | Inflammation Mediators - metabolism | Adult | Female | Interleukin-8 - metabolism | Neutrophils - metabolism | Neutrophils - pathology | Pyoderma Gangrenosum - metabolism | Cytokines - metabolism | Matrix Metalloproteinase 2 - metabolism | Receptors, Cell Surface - metabolism | Sweet Syndrome - pathology | CD3 Complex - metabolism | Pyoderma Gangrenosum - pathology | Interleukin-17 - metabolism | Antigens, Differentiation, Myelomonocytic - metabolism | Adolescent | Aged | Matrix Metalloproteinases - metabolism | Peroxidase - metabolism | Skin diseases | Cytokines | T cells | Macrophages | Vascular endothelial growth factor | Wounds | CD3 antigen | Inflammation | Leukocytes (neutrophilic) | Lymphocytes T | Matrix metalloproteinase | Gelatinase B | Inflammatory diseases | Interleukin 17 | Gelatinase A | CD163 antigen | Ulcers | Peroxidase | Immunoreactivity | Chemokines | Interleukin 8 | Tumor necrosis factor- alpha | Translational Studies
Journal Article
Scientific reports, ISSN 2045-2322, 2016, Volume 6, Issue 1, p. 38339
The obesity-associated inflammation of white adipose tissue (WAT) is one of the factors leading to the development of related diseases such as insulin... 
CELLS | OBESITY | ACTIVATION | ADIPOKINES | INSULIN-RESISTANCE | MULTIDISCIPLINARY SCIENCES | NECROSIS-FACTOR-ALPHA | MIR-146A | MICRORNAS | EXPRESSION | CANCER | Interleukin-8 - genetics | RNA, Small Interfering - genetics | MicroRNAs - antagonists & inhibitors | Oligonucleotide Array Sequence Analysis | Humans | MicroRNAs - metabolism | Intellectual Disability - metabolism | Heart Defects, Congenital - genetics | Macrophages - secretion | Oligoribonucleotides - metabolism | Genetic Diseases, X-Linked - genetics | MicroRNAs - agonists | p38 Mitogen-Activated Protein Kinases - metabolism | Interleukin-8 - metabolism | TNF Receptor-Associated Factor 6 - genetics | Arrhythmias, Cardiac - metabolism | Gigantism - metabolism | Signal Transduction | Intellectual Disability - pathology | Feedback, Physiological | Genetic Diseases, X-Linked - pathology | MAP Kinase Kinase 4 - genetics | Heart Defects, Congenital - metabolism | MicroRNAs - genetics | Adipocytes, White - metabolism | Oligoribonucleotides - genetics | RNA, Small Interfering - metabolism | Interleukin-1 Receptor-Associated Kinases - metabolism | Interleukin-1 Receptor-Associated Kinases - genetics | Adipose Tissue, White - metabolism | Culture Media, Conditioned - pharmacology | Intellectual Disability - genetics | Arrhythmias, Cardiac - pathology | Molecular Mimicry | Adipocytes, White - drug effects | MAP Kinase Kinase 4 - metabolism | Transfection | Female | Chemokine CCL2 - metabolism | Arrhythmias, Cardiac - genetics | Adipose Tissue, White - pathology | Gene Expression Regulation | Heart Defects, Congenital - pathology | p38 Mitogen-Activated Protein Kinases - genetics | Chemokine CCL2 - genetics | Inflammation | Genetic Diseases, X-Linked - metabolism | Macrophages - cytology | Adipocytes, White - pathology | Gigantism - genetics | TNF Receptor-Associated Factor 6 - metabolism | Primary Cell Culture | Adipose Tissue, White - drug effects | Gigantism - pathology | IRAK protein | Obesity | TRAF6 protein | Adipose tissue | Liver | JNK protein | mRNA | Adipocytes | Macrophages | Insulin | Steatosis | Fatty liver | Feedback | miRNA | Monocyte chemoattractant protein 1 | Interleukin 8
Journal Article
BMC gastroenterology, ISSN 1471-230X, 2016, Volume 16, Issue 1, p. 40
Background: Breastfeeding is associated with a variety of positive health outcomes in children and is recommended exclusively for the first 6 months of life;... 
Peyer's patches | GALT | Jejunum | Nutrition | Ileum | PIGS | EARLY INFANCY | PERMEABILITY | BARRIER | ENVIRONMENT | COLONIZATION | GUT MICROBIOTA | HUMAN-MILK | IMMUNE-RESPONSES | GASTROENTEROLOGY & HEPATOLOGY | Interleukin-8 - genetics | Up-Regulation | Jejunum - pathology | Cadherins - metabolism | Calcium - metabolism | Humans | Ileum - metabolism | Interleukin-8 - drug effects | Leukemia Inhibitory Factor - genetics | Vascular Endothelial Growth Factor A - metabolism | Peyer's Patches - drug effects | RNA, Messenger - metabolism | Vascular Endothelial Growth Factor A - genetics | Antigens, CD - genetics | Antigens, CD - metabolism | Jejunum - metabolism | Leukemia Inhibitory Factor - metabolism | Jejunum - drug effects | Fas Ligand Protein - drug effects | Ileum - drug effects | Swine | Interleukin-8 - metabolism | Cadherins - genetics | Soy Foods | Cytokines - genetics | Interleukin-6 - metabolism | Infant, Newborn | Milk | Animals, Newborn | Interleukin-6 - genetics | Down-Regulation | Interleukin-27 - genetics | Gastrointestinal Microbiome - drug effects | Diet | Interleukin-10 - genetics | Interleukin-15 - metabolism | Intestine, Small - metabolism | Peyer's Patches - immunology | Fas Ligand Protein - genetics | Fas Ligand Protein - metabolism | Ileum - pathology | Interferon-alpha - drug effects | Intestine, Small - pathology | Interferon-alpha - genetics | Interleukin-10 - metabolism | Interleukin-9 - metabolism | Vascular Endothelial Growth Factor A - drug effects | Interleukin-27 - metabolism | RNA, Messenger - drug effects | Interferon-alpha - metabolism | Cytokines - metabolism | Intestine, Small - microbiology | Jejunum - microbiology | Infant Formula - pharmacology | Animals | Interleukin-15 - genetics | Cytokines - drug effects | Interleukin-9 - genetics | Intestine, Small - drug effects | Leukemia Inhibitory Factor - drug effects | Ileum - microbiology | Interleukin-10 | Analysis | Influence | Research | Gene expression | Breast feeding | Health aspects
Journal Article
Nature communications, ISSN 2041-1723, 2018, Volume 9, Issue 1, pp. 191 - 13
The communication between tumor-derived elements and stroma in the metastatic niche has a critical role in facilitating cancer metastasis. Yet, the mechanisms... 
INVASION | MICROENVIRONMENT | BIOGENESIS | PROGNOSIS | MIRNA | MULTIDISCIPLINARY SCIENCES | GROWTH | MYOFIBROBLAST | STROMAL FIBROBLASTS | CARCINOMA | COMMUNICATION | Exosomes - metabolism | Interleukin-8 - genetics | Neoplasm Transplantation | Neoplastic Cells, Circulating - pathology | Cancer-Associated Fibroblasts - metabolism | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Neoplastic Cells, Circulating - metabolism | Male | Carcinoma, Hepatocellular - secondary | MicroRNAs - secretion | Lung Neoplasms - secondary | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms - pathology | Interleukin-8 - metabolism | Interleukin-6 - metabolism | Lung Neoplasms - genetics | Interleukin-6 - genetics | Liver Neoplasms - genetics | Signal Transduction | Neoplasm Invasiveness | Cell Communication | N-Acetyllactosamine Synthase - genetics | Integrin beta1 - metabolism | Cancer-Associated Fibroblasts - pathology | Animals | Mice, Nude | Liver Neoplasms - metabolism | Cell Line, Tumor | Exosomes - chemistry | Mice | MicroRNAs - genetics | N-Acetyllactosamine Synthase - metabolism | Cell Transformation, Neoplastic - pathology | Integrin beta1 - genetics | Carcinoma, Hepatocellular - metabolism | NF-κB protein | Cytokines | Tumor cells | Liver | Lung cancer | Crosstalk | Stroma | Hepatocellular carcinoma | Activation | Inflammation | Metastasis | Exosomes | Metastases | Interleukin 6 | Liver cancer | Signaling | Fibroblasts | Interleukin 8 | Cancer
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2012, Volume 7, Issue 1, p. e29985
...). Here we tested whether PGC-1 alpha overexpression could restructure the transcriptome and metabolism of primary cultured human skm cells, which display a phenotype that resembles the atrophic phenotype... 
COACTIVATOR 1-ALPHA PGC-1-ALPHA | OXIDATION | OVEREXPRESSION | PROTEIN | CHEMOKINES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | GENE-EXPRESSION | INCREASES | ALPHA | EXERCISE | Calmodulin - genetics | Interleukin-8 - genetics | Oligonucleotide Array Sequence Analysis | Humans | Transcriptome | Parvalbumins - metabolism | Muscle, Skeletal - metabolism | Mitochondrial Proteins - genetics | Muscle, Skeletal - cytology | Chemokine CCL8 - metabolism | Chemokine CXCL6 - metabolism | Electron Transport Complex IV - metabolism | Heat-Shock Proteins - genetics | Glycogen - metabolism | Mitochondrial Proteins - metabolism | Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha | Trans-Activators - genetics | Parvalbumins - genetics | Chemokine CCL5 - metabolism | Membrane Proteins - metabolism | Interleukin-8 - metabolism | Cytokines - genetics | Chemokine CXCL6 - genetics | Calmodulin - metabolism | Cytokines - metabolism | Membrane Proteins - genetics | Heat-Shock Proteins - metabolism | Cells, Cultured | Muscle Cells - metabolism | Electron Transport Complex IV - genetics | Transcription Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Muscle Cells - cytology | Triglycerides - metabolism | Transcription Factors - metabolism | Chemokine CCL5 - genetics | Chemokine CCL8 - genetics | Trans-Activators - metabolism | Lipids - analysis | Primary Cell Culture | Regulators | Phosphorylation | Biomedical research | Transcription | Calcium | Laboratories | Genes | Carbon dioxide | Lipids | Biosynthesis | Genomes | Glucose | Palmitic acid | Proteins | Calcium signalling | Atrophy | Mitochondria | Transgenic animals | Bioaccumulation | Rodents | Oxidation | Droplets | Phosphorylase kinase | Bioinformatics | Interleukin 8 | Fasting | Cytokines | Glycogen | Muscles | Triglycerides | Metabolism | Gene expression | Chemotaxis | Fatty acids | Phosphorylase | Skeletal muscle | Musculoskeletal system | DNA microarrays | Storage | Glycogen phosphorylase | Diabetes | Lactic acid | Bayesian analysis | Genètica molecular | Molecular genetics | Disorders of metabolism | Fisiologia patològica | Pathological physiology | Trastorns del metabolisme
Journal Article
Journal of Investigative Dermatology, ISSN 0022-202X, 2008, Volume 128, Issue 11, pp. 2625 - 2630
The critical role of IL-17 has recently been reported in a variety of conditions. Since IL-17 deeply participates in the pathogenesis of psoriasis and... 
INTERFERON-GAMMA | CHEMOKINE PRODUCTION | T(H)17 | IL-17 | GENE-EXPRESSION | GROWTH-FACTOR | DIFFERENTIATION | HUMAN KERATINOCYTES | T-LYMPHOCYTES | SKIN INFLAMMATION | DERMATOLOGY | Th1 Cells - pathology | Tumor Necrosis Factor-alpha - metabolism | Granulocyte-Macrophage Colony-Stimulating Factor - metabolism | Humans | Middle Aged | Male | Vascular Endothelial Growth Factor A - metabolism | Interleukin-17 - pharmacology | CD4-Positive T-Lymphocytes - pathology | Case-Control Studies | Interleukins - metabolism | Th1 Cells - metabolism | Psoriasis - pathology | Dermatitis, Atopic - etiology | Psoriasis - metabolism | Adult | Female | T-Lymphocytes, Helper-Inducer - pathology | Interleukin-8 - metabolism | Child | Th2 Cells - pathology | Dermis - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | CD4-Positive T-Lymphocytes - metabolism | Dermatitis, Atopic - pathology | Th2 Cells - metabolism | Interleukin-17 - metabolism | Adolescent | Dermis - pathology | Aged | Dermatitis, Atopic - metabolism | Cell Movement | Flow cytometry | Psoriasis | Dermatology | Granulocyte-macrophage colony-stimulating factor | Helper cells | Dermis | Interleukin 22 | Keratinocytes | Lymphocytes T | Interleukin 17 | Atopic dermatitis | CXCL10 protein | Eczema | Peripheral blood | gamma -Interferon | Skin diseases | Internet | Vascular endothelial growth factor | Interleukin 8 | Tumor necrosis factor- alpha
Journal Article
Chest, ISSN 0012-3692, 2015, Volume 147, Issue 6, pp. 1539 - 1548
Journal Article