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Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 08/2003, Volume 93, Issue 4, pp. 311 - 320
ABSTRACT—Homocysteine (Hcy) is an independent risk factor for cardiovascular disease. Monocyte chemoattractant protein-1 (MCP-1) and interleukin-8 (IL-8) are... 
Monocyte chemoattractant protein-1 | Monocytes | Homocysteine | Interleukin-8 | Atherosclerosis | homocysteine | atherosclerosis | monocytes | ENDOTHELIAL-CELL INJURY | OXIDATIVE STRESS | CARDIAC & CARDIOVASCULAR SYSTEMS | OXIDANT STRESS | monocyte chemoattractant protein-1 | RISK FACTOR | PLASMA HOMOCYST(E)INE | interleukin-8 | VASCULAR-DISEASE | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | ATHEROMATOUS PLAQUES | HEMATOLOGY | NF-KAPPA-B | T-LYMPHOCYTES | Interleukin-8 - genetics | Reactive Oxygen Species - metabolism | Chemokine CCL2 - secretion | Monocytes - cytology | Humans | Dimethyl Sulfoxide - pharmacology | Monocytes - metabolism | RNA, Messenger - metabolism | Pyrrolidines - pharmacology | Dose-Response Relationship, Drug | Thiocarbamates - pharmacology | Chromans - pharmacology | Time Factors | Homocysteine - pharmacology | Indoles - pharmacology | Interleukin-8 - secretion | Flavonoids - pharmacology | RNA, Messenger - drug effects | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Chemokine CCL2 - genetics | Imidazoles - pharmacology | Tyrphostins - pharmacology | Antioxidants - pharmacology | Onium Compounds - pharmacology | Sulfonamides - pharmacology | Naphthalenes - pharmacology | Gene Expression Regulation - drug effects | Monocytes - drug effects | Genistein - pharmacology | Pyridines - pharmacology | Thiazoles - pharmacology | Thiazolidinediones
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2003, Volume 462, Issue 1, pp. 193 - 198
The cytokine interleukin-17 may play a role in the recruitment of airway neutrophils, and interleukin-17 protein is increased in the airways of patients with... 
C-X-C chemokine | Interleukin-17 | Bronchial epithelial cell | human | Human | ACTIVATION | PROTEIN | MECHANISMS | CYTOKINE | NEUTROPHIL RECRUITMENT | bronchial epithelial cell, human | interleukin-17 | IN-VITRO | IL-17 | GENE-EXPRESSION | PHARMACOLOGY & PHARMACY | AIRWAYS | CYCLOSPORINE | Epithelial Cells - metabolism | Albuterol - pharmacology | Cyclosporine - pharmacology | Epithelial Cells - drug effects | Humans | Receptors, Glucocorticoid - metabolism | Interleukin-17 - pharmacology | Bronchi - drug effects | Dose-Response Relationship, Drug | Calcineurin Inhibitors | Intercellular Signaling Peptides and Proteins - metabolism | Chemotactic Factors - metabolism | Bronchi - metabolism | Flavonoids - pharmacology | Interleukin-8 - metabolism | Receptors, Adrenergic, beta - drug effects | Receptors, Adrenergic, beta - metabolism | Receptors, Glucocorticoid - drug effects | Bronchi - cytology | p38 Mitogen-Activated Protein Kinases | Enzyme Inhibitors - pharmacology | Adrenergic beta-Agonists - pharmacology | Imidazoles - pharmacology | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | ATP Binding Cassette Transporter, Subfamily B, Member 1 - antagonists & inhibitors | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Chemokines, CXC - metabolism | Chemokine CXCL1 | Chemokines - metabolism | Hydrocortisone - pharmacology | Pyridines - pharmacology | Chemokine CXCL6 | Cell Line, Transformed | Chemokines/secretion | Albuterol/pharmacology | Flavonoids/pharmacology | Adrenergic | beta/drug effects/metabolism | Epithelial Cells/drug effects/metabolism | Enzyme Inhibitors/pharmacology | Transformed | Adrenergic beta-Agonists/pharmacology | Ca(2+)-Calmodulin Dependent Protein Kinase/antagonists & inhibitors | Receptors | Imidazoles/pharmacology | Chemotactic Factors/secretion | Cyclosporine/pharmacology | Lungmedicin och allergi | Respiratory Medicine and Allergy | Bronchi/cytology/drug effects/metabolism | Drug | Intercellular Signaling Peptides and Proteins/secretion | Cell Line | P-Glycoprotein/antagonists & inhibitors | Interleukin-8/secretion | Hydrocortisone/pharmacology | Glucocorticoid/drug effects/metabolism | CXC/secretion | Interleukin-17/pharmacology | Mitogen-Activated Protein Kinases/antagonists & inhibitors | Calcineurin/antagonists & inhibitors | Dose-Response Relationship | Chemokines | Pyridines/pharmacology
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2012, Volume 167, Issue 4, pp. 775 - 786
BACKGROUND AND PURPOSE Patients with chronic obstructive pulmonary disease (COPD) show a poor response to corticosteroids, which has been linked to oxidative... 
salmeterol | corticosteroid | severe asthma | PI3Kδ | formoterol | oxidative stress | COPD | CELLS | COMBINATION THERAPY | INHALED CORTICOSTEROIDS | AIRWAY INFLAMMATION | BUDESONIDE | ADRENERGIC AGONISTS | INTERLEUKIN-8 | ASTHMA CONTROL | OBSTRUCTIVE PULMONARY-DISEASE | PHARMACOLOGY & PHARMACY | PI3Kd | Ethanolamines - pharmacology | Asthma - metabolism | Formoterol Fumarate | Albuterol - pharmacology | Humans | Middle Aged | Oxidative Stress - physiology | Male | Fluticasone | Adrenergic beta-2 Receptor Agonists - pharmacology | 1-Phosphatidylinositol 4-Kinase - metabolism | Young Adult | Dexamethasone - pharmacology | U937 Cells | Adult | Female | Interleukin-8 - metabolism | Pulmonary Disease, Chronic Obstructive - metabolism | Chromones - pharmacology | Salmeterol Xinafoate | Adenine - analogs & derivatives | Leukocytes, Mononuclear - drug effects | Hydrogen Peroxide - pharmacology | Adrenal Cortex Hormones - pharmacology | Albuterol - analogs & derivatives | Morpholines - pharmacology | 1-Phosphatidylinositol 4-Kinase - antagonists & inhibitors | Adenine - pharmacology | Drug Resistance - drug effects | Receptors, Adrenergic, beta-2 - metabolism | Budesonide - pharmacology | Androstadienes - pharmacology | Aged | Quinazolines - pharmacology | Hydrogen peroxide | Dexamethasone | Asthma | Steroids | Oxidative stress | Chronic obstructive pulmonary disease | Research Papers
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 08/2015, Volume 172, Issue 15, pp. 3805 - 3816
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2006, Volume 547, Issue 1, pp. 165 - 173
Cannabinoids are known to possess both anti-inflammatory and neuroprotective effects. In the present study, we have investigated the ability of cannabinoids to... 
Transmigration | Neutrophil | Cannabinoid | Chemotaxis | Interleukin 8 | ACTIVATION | POLYMORPHONUCLEAR LEUKOCYTES | cannabinoid | transmigration | INVOLVEMENT | ISCHEMIA | MODEL | neutrophil | MULTIPLE-SCLEROSIS | CEREBRAL-ARTERY OCCLUSION | ENDOTHELIAL-CELLS | PHARMACOLOGY & PHARMACY | RECEPTORS | RAT MICROGLIAL CELLS | chemotaxis | interleukin 8 | L-Lactate Dehydrogenase - secretion | Neutrophils - cytology | Cannabinoid Receptor Antagonists | Humans | Receptors, Cannabinoid - physiology | Benzoxazines | Dose-Response Relationship, Drug | Flow Cytometry | Piperidines - pharmacology | Dronabinol - analogs & derivatives | Indoles - pharmacology | Interleukin-8 - pharmacology | Interleukin-8 - secretion | Cyclohexanols - pharmacology | Dronabinol - pharmacology | Neutrophils - metabolism | Endocannabinoids | Pyrazoles - pharmacology | Cell Line | Endothelial Cells - metabolism | Neutrophils - drug effects | Morpholines - pharmacology | Chemotaxis - drug effects | Arachidonic Acids - pharmacology | Naphthalenes - pharmacology | Cell Movement - drug effects | Tumor Necrosis Factor-alpha - pharmacology | Cannabinoid Receptor Agonists | Analysis of Variance | Endothelial Cells - cytology | Receptors, Interleukin-8A - metabolism | Receptors, Interleukin-8B - metabolism | Polyunsaturated Alkamides - pharmacology | Thapsigargin - pharmacology | Endothelial Cells - drug effects | Cell Movement/drug effects | Polyunsaturated Alkamides/pharmacology | Dose-Response Relationship; Drug | Thapsigargin/pharmacology | Indoles/pharmacology | Receptors; Interleukin-8B/metabolism | Naphthalenes/pharmacology | Receptors; Interleukin-8A/metabolism | Tumor Necrosis Factor-alpha/pharmacology | Arachidonic Acids/pharmacology | Cyclohexanols/pharmacology | Receptors; Cannabinoid/agonists/antagonists & inhibitors/physiology | Morpholines/pharmacology | Tetrahydrocannabinol/analogs & derivatives/pharmacology | Neutrophils/cytology/drug effects/metabolism | Pyrazoles/pharmacology | Piperidines/pharmacology | L-Lactate Dehydrogenase/secretion | Chemotaxis/drug effects | Endothelial Cells/cytology/drug effects/metabolism | Interleukin-8/pharmacology/secretion
Journal Article
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2008, Volume 582, Issue 1, pp. 145 - 153
Journal Article
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 03/2016, Volume 75, Issue 3, pp. 593 - 600
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2013, Volume 8, Issue 3, p. e58129
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 09/2011, Volume 301, Issue 3, pp. C609 - C618
Bourcier C, Griseri P, Grepin R, Bertolotto C, Mazure N, Pages G. Constitutive ERK activity induces downregulation of tristetraprolin, a major protein... 
Extracellular-regulated kinase | Phosphorylation | CXCL8 | PHYSIOLOGY | AUTOPHAGY | KINASE P38 | CELL BIOLOGY | METASTATIC MELANOMA | EPITHELIAL-CELLS | extracellular-regulated kinase | B-RAF | RECEPTORS | phosphorylation | TUMOR-GROWTH | EXPRESSION | HUMAN CANCER | ENDOTHELIAL GROWTH-FACTOR | Interleukin-8 - genetics | RNA, Small Interfering - genetics | Gene Expression - genetics | Humans | Half-Life | Autophagy - physiology | RNA, Messenger - metabolism | Benzenesulfonates - pharmacology | Chemokine CXCL5 - pharmacology | Melanoma - prevention & control | Antibodies - immunology | Immunotherapy, Active - methods | Interleukin-8 - metabolism | Phosphorylation - drug effects | MAP Kinase Kinase Kinases - antagonists & inhibitors | Membrane Proteins - genetics | MAP Kinase Kinase Kinases - metabolism | Down-Regulation - genetics | Chemokine CXCL1 - immunology | Leupeptins - pharmacology | Tristetraprolin - genetics | Chemokine CXCL5 - immunology | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Proteasome Endopeptidase Complex - metabolism | Interleukin-8 - immunology | Niacinamide - analogs & derivatives | Gene Expression - drug effects | Microtubule-Associated Proteins - metabolism | Vaccination | Phenylurea Compounds | Dichlororibofuranosylbenzimidazole - pharmacology | Extracellular Signal-Regulated MAP Kinases - metabolism | RNA Stability - drug effects | Chemokine CXCL1 - pharmacology | Transfection | Tristetraprolin - metabolism | Female | Interleukin-8 - pharmacology | Antineoplastic Agents - pharmacology | Benzamides - pharmacology | Membrane Proteins - metabolism | Tumor Cells, Cultured | RNA Stability - physiology | Melanoma - metabolism | Proto-Oncogene Proteins - metabolism | RNA, Messenger - genetics | Genes, Reporter - genetics | Proto-Oncogene Proteins - genetics | Antibodies - pharmacology | Animals | Receptors, Interleukin-8B - metabolism | Cell Proliferation - drug effects | Pyridines - pharmacology | Apoptosis - physiology | Proteasome Inhibitors | Messenger RNA | Melanoma | Physiological aspects | Cytogenetics | Development and progression | Research | Gene expression | Properties
Journal Article
Journal Article