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Journal Article
PLoS ONE, ISSN 1932-6203, 08/2017, Volume 12, Issue 8, p. e0182658
Moringa oleifera Lam. is a tropical plant, used for centuries as food and traditional medicine. The aim of this study was to develop, validate and... 
ANTITUMOR PROMOTER | ACTIVATION | NRF2 | CURCUMIN | NITRIC-OXIDE SYNTHASE | ANTIOXIDANT | MULTIDISCIPLINARY SCIENCES | NF-KB | GENE-EXPRESSION PROFILES | STRUCTURAL INFLUENCE | Plant Extracts - chemistry | Antioxidants - chemistry | Plant Extracts - pharmacology | Curcumin - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Moringa oleifera - chemistry | Inflammation - drug therapy | Isothiocyanates - chemistry | Hindlimb - immunology | Seeds - chemistry | Phytotherapy | Drug Evaluation, Preclinical | Disease Models, Animal | Phytochemicals - chemistry | Cell Line | Edema - immunology | Plant Extracts - isolation & purification | Edema - drug therapy | Inflammation - immunology | Antioxidants - pharmacology | Random Allocation | Rats, Sprague-Dawley | Phytochemicals - isolation & purification | Macrophages - metabolism | Animals | Antioxidants - isolation & purification | Hindlimb - drug effects | Macrophages - drug effects | Carrageenan | Phytochemicals - pharmacology | Curcuma - chemistry | Antioxidants | Anti-inflammatory drugs | Physiological aspects | Research | Properties | Materia medica, Vegetable | Plant extracts | Disorders | Plant biology | Lipopolysaccharides | Proteins | Interleukins | Glutathione transferase | Biocompatibility | Medicinal plants | Carbohydrates | Enzymes | Cytokines | Gene expression | Fatty acids | Studies | Mitigation | Flavonoids | Nitric oxide | Minimum inhibitory concentration | Fats | In vitro methods and tests | Enrichment | Oxidative stress | Food plants | Seeds | Oxidoreductase | Kinases | Inflammatory diseases | Optimization | Interleukin 6 | Rodents | Heme | Interleukin 1 | Glycosides | Tumor necrosis factor-TNF | Curcumin | Nonsteroidal anti-inflammatory drugs | Pharmaceutical sciences | Glutathione | Food | Chronic illnesses | Edema | Aspirin | Antiinflammatory agents | Isothiocyanate | Inflammation | NAD | Natural products | Phenols | Cancer
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2017, Volume 25, Issue 21, pp. 5904 - 5916
Journal Article
Biosensors and Bioelectronics, ISSN 0956-5663, 07/2017, Volume 93, pp. 170 - 175
Journal Article
Carbohydrate Polymers, ISSN 0144-8617, 01/2019, Volume 204, pp. 142 - 151
The present work investigated the antioxidative, anti-inflammatory and pulmonary protective effects of enzymatic- and acid- hydrolysed mycelia polysaccharides... 
Oudemansiella radicata | Acute lung injury | Antioxidant | Pulmonary protective | Anti-inflammatory | Enzymatic- acid- hydrolysed mycelia polysaccharide | FRUITING BODY | SIGNALING PATHWAYS | POLYMER SCIENCE | CHEMISTRY, ORGANIC | ANTITUMOR-ACTIVITY | ANTIAGING ACTIVITIES | ZINC POLYSACCHARIDES | IN-VITRO | LIPOPOLYSACCHARIDE | MICE | PLEUROTUS-DJAMOR | CHEMISTRY, APPLIED | NF-KAPPA-B | Cellulase - chemistry | Tumor Necrosis Factor-alpha - metabolism | Lung Injury - pathology | Antioxidants - chemistry | Polygalacturonase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Interleukin-1alpha - metabolism | Male | Protective Agents - chemistry | Protective Agents - therapeutic use | Polysaccharides - toxicity | Polysaccharides - chemistry | Lung Injury - drug therapy | Interleukin-6 - metabolism | Polysaccharides - therapeutic use | Lung - pathology | Glucuronidase - chemistry | Anti-Inflammatory Agents, Non-Steroidal - toxicity | Multienzyme Complexes - chemistry | Antioxidants - toxicity | Hydrolysis | Antioxidants - therapeutic use | Animals | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Mice | Mycelium - chemistry | Protective Agents - toxicity | Agaricales - chemistry | Antioxidants | Acute respiratory distress syndrome | Prevention | Enzymes | Polysaccharides | C-reactive protein | Interleukins | Anti-inflammatory drugs | Analysis | Superoxide | Mitogens | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2009, Volume 4, Issue 10, p. e7116
The antiinflammatory protein annexin-1 (ANXA1) and the adaptor S100A10 (p11), inhibit cytosolic phospholipase A2 (cPLA2 alpha) by direct interaction. Since the... 
TRANSMEMBRANE CONDUCTANCE REGULATOR | COX-2 EXPRESSION | CYTOSOLIC PHOSPHOLIPASE A | EPITHELIAL-CELLS | MULTIDISCIPLINARY SCIENCES | PULMONARY INFLAMMATION | LIPID RAFTS | INNATE IMMUNE-RESPONSE | GENE-EXPRESSION | CYSTIC-FIBROSIS | NECROSIS-FACTOR-RECEPTOR | Surface Plasmon Resonance | Tumor Necrosis Factor-alpha - metabolism | Eicosanoids - chemistry | Humans | Membrane Microdomains - chemistry | Phospholipids - chemistry | Cystic Fibrosis Transmembrane Conductance Regulator - chemistry | Cholesterol - chemistry | Animals | Group IV Phospholipases A2 - metabolism | Cell Line, Tumor | Protein Binding | Cell Membrane - metabolism | Mice | Interleukin-8 - metabolism | Kinetics | Interleukin-8 - chemistry | Proteins | Analysis | Prostaglandins E | Lipids | Cystic fibrosis | Cyclodextrins | Inflammation | B cells | Arachidonic acid | Annexins | Protein binding | Phosphorylation | Membranes | Prostaglandin E2 | Eicosanoids | Smooth muscle | Infections | Activation | Phospholipids | Kinases | S100 protein | Cell growth | Synthesis | Calcium-binding protein | Cell cycle | Tumor necrosis factor-TNF | Inhibition | Interleukin 8 | Pathogens | Phospholipase A2 | Membrane composition | Exposure | Tumor necrosis factor-α | Phospholipase | Cyclodextrin | Inhibitors | Nitric oxide | Fibrosis | DRM protein | Proteomics | Ligands | Cholera | Mutation | Disruption | Destabilization | Organic chemistry | Chemical Sciences
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2017, Volume 18, Issue 9, p. 1985
Human lactoferrin (hLf), an iron-binding multifunctional cationic glycoprotein secreted by exocrine glands and by neutrophils, is a key element of host... 
Lactoferrin | Cytokines | Anemia | Homeostasis | Inflammation | Iron | Athletes | Oral care | STREPTOCOCCUS-MUTANS | HUMAN-MILK LACTOFERRIN | PORPHYROMONAS-GINGIVALIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | oral care | athletes | MATERNAL SERUM INTERLEUKIN-6 | CHEMISTRY, MULTIDISCIPLINARY | anemia | 3-DIMENSIONAL STRUCTURE | homeostasis | inflammation | PSEUDOMONAS-AERUGINOSA | lactoferrin | iron | cytokines | HEPCIDIN EXPRESSION | BINDING-PROPERTIES | BOVINE LACTOFERRIN | Anti-Infective Agents - metabolism | Anti-Infective Agents - pharmacology | Humans | Glycoproteins - metabolism | Structure-Activity Relationship | Glycoproteins - pharmacology | Anti-Inflammatory Agents - metabolism | Inflammation - complications | Inflammation - metabolism | Lactoferrin - pharmacology | Anti-Infective Agents - chemistry | Female | Glycoproteins - chemistry | Premature Birth - prevention & control | Anemia - etiology | Glycoproteins - genetics | Lactoferrin - metabolism | Anti-Inflammatory Agents - pharmacology | Anemia, Iron-Deficiency - etiology | Iron - chemistry | Premature Birth - metabolism | Iron - metabolism | Lactoferrin - genetics | Pregnancy | Anemia - metabolism | Lactoferrin - chemistry | Animals | Anti-Inflammatory Agents - chemistry | Inflammation - genetics | Protein Binding | Oral Health | Anemia, Iron-Deficiency - metabolism | Transferrin | Glands | Interleukin | Ferritin | Homology | Interleukin 6 | Next-generation sequencing | Bacteria | Supplementation | Binding | Antiinflammatory agents | Dietary supplements | Glycoprotein | Oral administration | Cures | Leukocytes (neutrophilic) | Exocrine glands | Biofilms
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 09/2018, Volume 19, Issue 9, p. 2494
Periodontal disease, a chronic disease caused by bacterial infection, eventually progresses to severe inflammation and bone loss. Regulating excessive... 
Litsea japonica leaf extract | Periodontal disease | Periodontal ligament | Inflammation | IL-8 | IL-6 | TRADITIONAL KOREAN MEDICINE | BIOACTIVE COMPOUNDS | TREPONEMA-DENTICOLA | CELL VIABILITY | PORPHYROMONAS-GINGIVALIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | periodontal ligament | MICROBIOTA | CHEMISTRY, MULTIDISCIPLINARY | periodontal disease | HUMAN GINGIVAL FIBROBLASTS | inflammation | TANNERELLA-FORSYTHIA | GENE-EXPRESSION | NF-KAPPA-B | Molar - surgery | Plant Extracts - chemistry | Interleukin-1beta - pharmacology | Interleukin-6 - antagonists & inhibitors | Plant Extracts - pharmacology | Porphyromonas gingivalis - pathogenicity | Treponema denticola - pathogenicity | Coculture Techniques | Humans | Periodontal Ligament - surgery | Porphyromonas gingivalis - chemistry | Lipopolysaccharides - antagonists & inhibitors | Healthy Volunteers | Treponema denticola - growth & development | Porphyromonas gingivalis - growth & development | Periodontal Ligament - cytology | Treponema denticola - chemistry | Molar - cytology | Adult | Tannerella forsythia - pathogenicity | Fibroblasts - microbiology | Interleukin-1beta - antagonists & inhibitors | Plant Leaves - chemistry | Cell Survival - drug effects | Anti-Inflammatory Agents - pharmacology | Bicuspid - cytology | Interleukin-8 - biosynthesis | Interleukin-8 - antagonists & inhibitors | Litsea - chemistry | Tannerella forsythia - growth & development | Tannerella forsythia - chemistry | Anti-Inflammatory Agents - chemistry | Fusobacterium nucleatum - chemistry | Bicuspid - surgery | Fibroblasts - drug effects | Interleukin-6 - immunology | Lipopolysaccharides - pharmacology | Fusobacterium nucleatum - pathogenicity | Interleukin-6 - biosynthesis | Fibroblasts - immunology | Fibroblasts - cytology | Primary Cell Culture | Interleukin-8 - immunology | Fusobacterium nucleatum - growth & development | Toxicity | Interleukin | Chronic infection | Cytotoxicity | Infections | mRNA | Lipopolysaccharides | Interleukin 6 | Proteins | Connective tissues | Leaves | Stimulants | Interleukin 1 | Fibroblasts | Bacteria | Pretreatment | Bone loss | Interleukin 8 | Antiinflammatory agents | Bacterial infections | Cytokines | Alveolar bone | Gene expression | Periodontal diseases | Periodontitis | Diabetic retinopathy | Disease | Biochemistry | E coli | Rodents | Research centers | Pathogens | Dentistry | IL-1β | Biofilms | Natural products | Diabetes | Ligaments
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2013, Volume 8, Issue 12, p. e83077
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 07/2013, Volume 148, Issue 2, pp. 563 - 569
Atherosclerosis (AS) can result in severe cardiovascular diseases. Early indications of AS include disorders in lipid metabolism, inflammatory responses, and... 
Crataegus pinnatifida Bge. var. major N.E.Br | Aqueous extract | Lipid-lowering | Endothelial protection | Anti-inflammation | Atherosclerosis | Crataegus pinnatifida Bge. var. major N.E.Br. Aqueous extract Atherosclerosis Lipid-lowering Anti-inflammation Endothelial protection | CHEMISTRY, MEDICINAL | PLANT SCIENCES | PROFILE | DIET | INTEGRATIVE & COMPLEMENTARY MEDICINE | DISEASE | HAWTHORN | PHARMACOLOGY & PHARMACY | DYSLIPIDEMIA | Crataegus pinnatifida Bge. var. major NEBr | Biflavonoids - pharmacology | Plant Extracts - chemistry | Biflavonoids - chemistry | Rats, Wistar | Chlorogenic Acid - pharmacology | Plant Extracts - pharmacology | Rutin - pharmacology | Drugs, Chinese Herbal - pharmacology | Male | Interleukins - metabolism | Endothelins - blood | Proanthocyanidins - chemistry | C-Reactive Protein - metabolism | Proanthocyanidins - pharmacology | Diet, High-Fat | Lipids - blood | Water - chemistry | Catechin - pharmacology | Nitric Oxide - blood | Quercetin - analogs & derivatives | Atherosclerosis - drug therapy | Quercetin - chemistry | Fruit - chemistry | Rats | Random Allocation | Atherosclerosis - metabolism | Atherosclerosis - blood | Animals | Quercetin - pharmacology | Crataegus - chemistry | Rutin - chemistry | Thromboxane B2 - blood | Chlorogenic Acid - chemistry | 6-Ketoprostaglandin F1 alpha - blood | Catechin - chemistry | Prevention | Antioxidants | Heart diseases | Statins
Journal Article
Journal Article