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The Journal of Immunology, ISSN 0022-1767, 02/2004, Volume 172, Issue 4, pp. 2126 - 2136
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2004, Volume 172, Issue 4, pp. 2137 - 2146
Ideal vaccines should be stable, safe, molecularly defined, and out-of-shelf reagents efficient at triggering effector and memory Ag-specific T cell-based... 
DOUBLE-STRANDED-RNA | NECROSIS-FACTOR | HUMAN DENDRITIC CELLS | CLINICAL-TRIAL | IMMUNE-RESPONSES | IN-VIVO | TOLL-LIKE RECEPTORS | IMMUNOLOGY | SYNTHETIC IMMUNOMODULATOR MURABUTIDE | BACTERIAL-DNA | MURAMYL PEPTIDES | Endosomes - immunology | HLA-A2 Antigen - genetics | Oligodeoxyribonucleotides - administration & dosage | Toll-Like Receptor 3 | Adjuvants, Immunologic - administration & dosage | Membrane Glycoproteins - metabolism | Humans | Membrane Glycoproteins - biosynthesis | Neoplasm Proteins - immunology | Toll-Like Receptor 9 | Interphase - immunology | T-Lymphocytes, Regulatory - immunology | DNA-Binding Proteins - metabolism | gp100 Melanoma Antigen | Toll-Like Receptors | Melanoma, Experimental - prevention & control | HLA-A2 Antigen - biosynthesis | Melanoma, Experimental - immunology | Adjuvants, Immunologic - metabolism | T-Lymphocytes, Regulatory - cytology | Membrane Glycoproteins - immunology | Neoplasm Proteins - genetics | Oligodeoxyribonucleotides - metabolism | Cell-Free System - immunology | T-Lymphocytes, Cytotoxic - immunology | CpG Islands - immunology | Oligodeoxyribonucleotides - immunology | HLA-A2 Antigen - immunology | Neoplasm Proteins - biosynthesis | Cancer Vaccines - administration & dosage | Receptors, Cell Surface - metabolism | Vaccines, Subunit - immunology | Cell-Free System - transplantation | Endosomes - transplantation | Membrane Glycoproteins - genetics | Cancer Vaccines - immunology | Animals | T-Lymphocytes, Cytotoxic - metabolism | Vaccines, Subunit - administration & dosage | RNA, Double-Stranded - immunology | Ligands | Mice | Graft Rejection - immunology | T-Lymphocytes, Cytotoxic - cytology
Journal Article
The Journal of Immunology, ISSN 0022-1767, 04/2003, Volume 170, Issue 8, pp. 4069 - 4076
It is widely believed that generation of mature dendritic cells (DCs) with full T cell stimulatory capacity from human monocytes in vitro requires 5-7 days of... 
IL-12 PRODUCTION | IN-VITRO | ACTIVATION | RECEPTOR EXPRESSION | ALPHA COOPERATE | SUBSETS | CD40 LIGAND | INTERLEUKIN-12 | IMMUNOLOGY | MATURATION | PROSTAGLANDIN-E2 | Stem Cells - immunology | Dendritic Cells - immunology | Humans | Interphase - immunology | Monocytes - immunology | Cell Culture Techniques - methods | Interleukin-4 - pharmacology | Lymphocyte Activation - immunology | Dextrans - immunology | Time Factors | Inflammation Mediators - pharmacology | Chemokines, CXC - pharmacology | Endocytosis - immunology | Interleukin-12 - biosynthesis | Dextrans - metabolism | Dinoprostone - pharmacology | Chemokines, CC - pharmacology | Solubility | Interleukin-12 - metabolism | Second Messenger Systems - immunology | Interleukin-1 - pharmacology | Receptors, CXCR4 - metabolism | Cell Differentiation - immunology | Tumor Necrosis Factor-alpha - pharmacology | CD40 Ligand - pharmacology | Ligands | Tetanus Toxoid - immunology | T-Lymphocyte Subsets - immunology | Monocytes - cytology | Interleukin-12 - physiology | Chemokine CCL21 | Monocytes - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Epitopes, T-Lymphocyte - immunology | Dendritic Cells - metabolism | Chemokine CXCL12 | Receptors, CCR7 | Receptors, Chemokine - metabolism | Stromal Cells - metabolism | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Immunophenotyping | Stromal Cells - immunology | Chemokines, CXC - metabolism | Dendritic Cells - cytology | Drug Combinations | Interferon-gamma - biosynthesis | Chemokines, CC - metabolism
Journal Article
The Journal of Immunology, ISSN 0022-1767, 03/2001, Volume 166, Issue 6, pp. 3789 - 3796
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 02/2001, Volume 166, Issue 4, pp. 2717 - 2726
Microglia subpopulations were studied in mouse experimental autoimmune encephalomyelitis and toxoplasmic encephalitis, CNS inflammation was associated with the... 
COLONY-STIMULATING FACTOR | INDUCE | EXPERIMENTAL ALLERGIC ENCEPHALOMYELITIS | DISEASE | TOXOPLASMIC ENCEPHALITIS | ANTIGEN-PRESENTING CELLS | CHOROID-PLEXUS | MICROGLIAL CELLS | IMMUNOLOGY | CULTURES | T-CELLS | Leukocytes, Mononuclear - metabolism | Microglia - metabolism | Coculture Techniques | Dendritic Cells - immunology | Encephalomyelitis, Autoimmune, Experimental - immunology | Interphase - immunology | CD40 Ligand - immunology | Brain - metabolism | Th1 Cells - metabolism | Brain - ultrastructure | Microglia - pathology | Macrophages - ultrastructure | Nitric Oxide - biosynthesis | Macrophages - pathology | Lymphocyte Activation | Mice, Transgenic | Cell Differentiation - immunology | Macrophages - metabolism | CD40 Ligand - pharmacology | Dendritic Cells - ultrastructure | Brain - pathology | Mice | Mice, Inbred BALB C | Macrophage-1 Antigen - biosynthesis | Toxoplasmosis, Animal - pathology | T-Lymphocyte Subsets - immunology | Toxoplasmosis, Animal - metabolism | Encephalomyelitis, Autoimmune, Experimental - metabolism | Dendritic Cells - pathology | Integrin alphaXbeta2 - biosynthesis | Th1 Cells - immunology | Cellular Senescence - immunology | CD40 Ligand - metabolism | Microglia - immunology | Leukocytes, Mononuclear - immunology | Female | Leukocyte Count | Dendritic Cells - metabolism | Macrophages - immunology | Encephalomyelitis, Autoimmune, Experimental - pathology | Mice, Inbred C57BL | Cells, Cultured | Granulocyte-Macrophage Colony-Stimulating Factor - pharmacology | Immunophenotyping | Animals | Microglia - ultrastructure | Toxoplasmosis, Animal - immunology | Brain - immunology | Cytokines - biosynthesis
Journal Article
The Journal of Immunology, ISSN 0022-1767, 08/2001, Volume 167, Issue 3, pp. 1313 - 1324
A costimulatory member of the TNFR family, 4-1BB, is expressed on activated T cells. Although some reports have suggested that 4-1BB is primarily involved in... 
RESPONSES | OX40 LIGAND | CO-STIMULATION | IN-VIVO | COSTIMULATORY MOLECULE | RECEPTOR | FACTOR-KAPPA-B | IMMUNOLOGY | M12 B-LYMPHOMAS | MICE LACKING | ANTIGEN | Lymphocytic choriomeningitis virus - immunology | CD8-Positive T-Lymphocytes - cytology | Ovalbumin - immunology | Viral Proteins - immunology | Molecular Sequence Data | Antigens, Viral - genetics | Interphase - immunology | Receptors, OX40 | 4-1BB Ligand | Lymphocyte Culture Test, Mixed | CD4-Positive T-Lymphocytes - immunology | Lymphocyte Activation - genetics | Cell Division - immunology | Peptide Fragments - immunology | CD8-Positive T-Lymphocytes - metabolism | Epitopes, T-Lymphocyte - immunology | Tumor Cells, Cultured | Tumor Necrosis Factor Receptor Superfamily, Member 7 - biosynthesis | Peptide Fragments - genetics | Glycoproteins - genetics | Ovalbumin - genetics | Amino Acid Sequence | Adjuvants, Immunologic - physiology | Antibodies, Monoclonal - pharmacology | CD4-Positive T-Lymphocytes - cytology | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Cells, Cultured | Viral Proteins - genetics | Mice, Transgenic | CD28 Antigens - immunology | Cell Survival - immunology | Mice, Knockout | Drug Synergism | Antigens, Viral - immunology | Glycoproteins - immunology | Animals | Receptors, Tumor Necrosis Factor | CD3 Complex - immunology | Tumor Necrosis Factor-alpha - physiology | Lymphocytic choriomeningitis virus - genetics | Ligands | Mice | Mice, Inbred BALB C | Receptors, Antigen, T-Cell - genetics | CD8-Positive T-Lymphocytes - immunology | Tumor Necrosis Factor-alpha - biosynthesis
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2000, Volume 165, Issue 7, pp. 3742 - 3755
Journal Article
Immunity, ISSN 1074-7613, 2000, Volume 13, Issue 4, pp. 485 - 495
Infection of humans with Epstein-Barr virus (EBV) may cause infectious mononucleosis (IM). Analysis of single EBV-infected cells from tonsils of IM patients... 
REED-STERNBERG CELLS | HODGKINS-DISEASE | IN-VIVO | LYMPHOCYTES-B | ACTIVATED CD40 | GERMINAL-CENTERS | IMMUNOLOGY | MEMBRANE-PROTEIN LMP1 | EPSTEIN-BARR-VIRUS | CD8(+) T-CELLS | MOLECULAR ANALYSIS | Hodgkin Disease - virology | Infectious Mononucleosis - immunology | Hodgkin Disease - pathology | Germinal Center - immunology | Herpesvirus 4, Human - growth & development | Humans | Molecular Sequence Data | Interphase - immunology | Male | Palatine Tonsil - immunology | Organ Specificity - immunology | Cell Differentiation - genetics | Herpesvirus 4, Human - isolation & purification | Polymerase Chain Reaction | Adult | B-Lymphocyte Subsets - immunology | Female | Clone Cells | Gene Rearrangement, B-Lymphocyte | Herpesvirus 4, Human - pathogenicity | Genetic Variation - immunology | B-Lymphocyte Subsets - virology | B-Lymphocyte Subsets - pathology | Infectious Mononucleosis - pathology | Herpesvirus 4, Human - immunology | Immunophenotyping | Virus Replication - immunology | Germinal Center - pathology | Reed-Sternberg Cells - immunology | Gene Expression Regulation, Viral - immunology | Cell Differentiation - immunology | Palatine Tonsil - pathology | Reed-Sternberg Cells - pathology | Infectious Mononucleosis - virology | B-Lymphocyte Subsets - metabolism | Germinal Center - virology | Adolescent | Palatine Tonsil - virology | Hodgkin Disease - immunology | Immunologic Memory | Reed-Sternberg Cells - virology | Virus Latency - immunology
Journal Article
Journal Article
The Journal of Immunology, ISSN 0022-1767, 10/2003, Volume 171, Issue 8, pp. 4447 - 4453
The main failure of antiretroviral therapy is the lack of restoration of HIV-specific CD4(+) T cells. IL-7, which has been shown to be a crucial cytokine for... 
RECENT THYMIC EMIGRANTS | ACTIVE ANTIRETROVIRAL THERAPY | PROLIFERATION | RESTORATION | MICE | DIFFERENTIATION | IMMUNOLOGY | THYMOCYTES | HUMAN-IMMUNODEFICIENCY-VIRUS-1 | INTERLEUKIN-7 | LYMPHOCYTES | T-Lymphocyte Subsets - immunology | CD8-Positive T-Lymphocytes - cytology | Simian Acquired Immunodeficiency Syndrome - metabolism | Dose-Response Relationship, Immunologic | T-Lymphocyte Subsets - cytology | Humans | Interleukin-7 - physiology | Interphase - immunology | Macaca mulatta | Viral Load | Interleukin-7 - administration & dosage | CD4-Positive T-Lymphocytes - immunology | CD4-CD8 Ratio | Lymphocyte Activation - immunology | Simian Acquired Immunodeficiency Syndrome - virology | Cell Division - immunology | CD8-Positive T-Lymphocytes - metabolism | Drug Evaluation, Preclinical | Simian Immunodeficiency Virus - immunology | CD4-Positive T-Lymphocytes - cytology | CD4-Positive T-Lymphocytes - metabolism | Virus Replication - immunology | Lymph Nodes - virology | Lymph Nodes - immunology | Recombinant Proteins - pharmacology | Simian Acquired Immunodeficiency Syndrome - blood | Recombinant Proteins - administration & dosage | Simian Immunodeficiency Virus - physiology | Hematopoiesis - immunology | Animals | Gene Rearrangement, T-Lymphocyte - immunology | Simian Acquired Immunodeficiency Syndrome - immunology | Up-Regulation - immunology | Down-Regulation - immunology | T-Lymphocyte Subsets - metabolism | CD8-Positive T-Lymphocytes - immunology
Journal Article
Immunity, ISSN 1074-7613, 2000, Volume 13, Issue 4, pp. 497 - 506
Journal Article