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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 08/2015, Volume 112, Issue 32, pp. 10038 - 10043
... cytotoxicity was sustained in these mice. Colon mucosa transcriptomics revealed that antibiotics block heme-induced differential expression of oncogenes, tumor suppressors, and cell turn... 
Immunohistochemistry | Up-Regulation | Body Weight | Cell Proliferation | Biological Markers | Male | Mucus | Colony Count, Microbial | Journal Article | Antioxidants | Sulfides | Anti-Bacterial Agents | Microbiota | Ki-67 Antigen | Cell Death | Heme | Colon | Feces | Intestinal Mucosa | Down-Regulation | Mice, Inbred C57BL | Epithelial Cells | Animals | Cell Cycle | Diet | Models, Biological | Research Support, Non-U.S. Gov't | Mucolysis | (Tri)sulfides | Red meat | Mucus barrier | Colorectal cancer | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Cycle - genetics | Epithelial Cells - metabolism | Epithelial Cells - drug effects | Colon - drug effects | Microbiota - drug effects | Body Weight - drug effects | Ki-67 Antigen - metabolism | Mucus - drug effects | Intestinal Mucosa - drug effects | Feces - microbiology | Heme - pharmacology | Mucus - metabolism | Sulfides - metabolism | Cell Death - drug effects | Biomarkers - metabolism | Colon - pathology | Epithelial Cells - pathology | Up-Regulation - genetics | Antioxidants - pharmacology | Intestinal Mucosa - microbiology | Down-Regulation - drug effects | Down-Regulation - genetics | Up-Regulation - drug effects | Anti-Bacterial Agents - pharmacology | Cell Proliferation - drug effects | Colon - microbiology | Cell Cycle - drug effects | Intestinal Mucosa - pathology | Cell proliferation | Colon cancer | Epithelial cells | Physiological aspects | Observations | Health aspects | Index Medicus | Biological Sciences | colorectal cancer | mucus barrier | (tri)sulfides | mucolysis | red meat | susceptibility | expression | bacterial | inhibitor | mucin | fat | colorectal-cancer | mice | cytotoxicity
Journal Article
Journal Article
Journal Article
Scientific reports, ISSN 2045-2322, 01/2016, Volume 6, Issue 1, pp. 19200 - 19200
Although the heavy metals cadmium (Cd) and lead (Pb) are known environmental health concerns, their long-term impacts on gut ecology and susceptibility to... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Immunomodulation - drug effects | Dextran Sulfate - adverse effects | Colitis - pathology | Salmonella typhimurium | Intestinal Mucosa - drug effects | Cadmium - adverse effects | Lead - adverse effects | Trinitrobenzenesulfonic Acid - adverse effects | Time Factors | Immune System - immunology | Female | Metals, Heavy - administration & dosage | Disease Models, Animal | Metals, Heavy - adverse effects | Disease Susceptibility | Salmonella Infections - complications | Administration, Oral | Immune System - cytology | Colitis - etiology | Animals | Immune System - drug effects | Salmonella Infections - microbiology | Mice | Lead - administration & dosage | Cadmium - administration & dosage | Intestinal Mucosa - pathology | Salmonella | Cell culture | Cadmium | Drinking water | Inflammatory bowel diseases | Animal models | Digestive system | Sulfonic acid | Heavy metals | Dextran | Inflammatory bowel disease | Immunosuppression | Sodium | Intestine | Sodium sulfate | Rodents | Colon | Sulfate | Colitis | Autoimmune diseases | Digestive tract | Index Medicus | Dextran Sulfate/adverse effects | Disease Models | Trinitrobenzenesulfonic Acid/adverse effects | Metals | Heavy/adverse effects | Toxicology and food chain | Colitis/pathology | Immune System/immunology | Intestinal Mucosa/pathology | Intestinal Mucosa/drug effects | Life Sciences | Toxicology | Immunomodulation/drug effects | Salmonella Infections/microbiology | Animal | Colitis/etiology | Cadmium/administration & dosage
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2010, Volume 159, Issue 6, pp. 1236 - 1246
.... The use of non-steroidal anti-inflammatory drugs continues to be limited by their toxicity, particularly in the upper gastrointestinal tract... 
gastrointestinal | naproxen | blood pressure | arthritis | inflammation | cyclooxygenase | ulcer | hydrogen sulphide | non-steroidal anti-inflammatory drug | mucosal defence | non‐steroidal anti‐inflammatory drug | Hydrogen sulphide | Cyclooxygenase | Mucosal defence | Naproxen | Non-steroidal anti-inflammatory drug | Ulcer | Arthritis | Blood pressure | Inflammation | Gastrointestinal | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Hydrogen Sulfide - metabolism | Naproxen - analogs & derivatives | Arthritis, Experimental - drug therapy | Intestinal Mucosa - metabolism | Rats, Wistar | Dinoprostone - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Gastric Mucosa - metabolism | Intestinal Mucosa - drug effects | Stomach Ulcer - enzymology | Arthritis, Experimental - metabolism | Intestine, Small - enzymology | Naproxen - pharmacokinetics | Intestinal Mucosa - enzymology | Gastric Mucosa - drug effects | Blood Pressure - drug effects | Molecular Structure | Hypertension - enzymology | Naproxen - analysis | Naproxen - adverse effects | Stomach Ulcer - metabolism | Gastric Mucosa - enzymology | Stomach Ulcer - drug therapy | Rats | Naproxen - therapeutic use | Hypertension - metabolism | Naproxen - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Intestine, Small - drug effects | Cyclooxygenase 2 - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Arthritis, Experimental - enzymology | Cyclooxygenase 1 - metabolism | Intestine, Small - metabolism | Toxicity | Rodents | Ulcers | Index Medicus | Research Papers
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Journal Article