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Science, ISSN 0036-8075, 08/2014, Volume 345, Issue 6202, pp. 1254009 - 1310
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 03/2010, Volume 159, Issue 6, pp. 1236 - 1246
Background and purpose:  Hydrogen sulphide is an important mediator of gastric mucosal defence. The use of non-steroidal anti-inflammatory drugs continues to... 
gastrointestinal | naproxen | blood pressure | arthritis | inflammation | cyclooxygenase | ulcer | hydrogen sulphide | non-steroidal anti-inflammatory drug | mucosal defence | Hydrogen sulphide | Cyclooxygenase | Mucosal defence | Naproxen | Non-steroidal anti-inflammatory drug | Ulcer | Arthritis | Blood pressure | Inflammation | Gastrointestinal | RHEUMATOID-ARTHRITIS | MUCOSAL LESIONS | OXIDE DONATOR NAPROXCINOD | GASTROINTESTINAL-TRACT | BLOOD-PRESSURE | SELECTIVE CYCLO-OXYGENASE-2 INHIBITORS | GASTRIC DAMAGE | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | GROWTH-FACTOR | Hydrogen Sulfide - metabolism | Naproxen - analogs & derivatives | Arthritis, Experimental - drug therapy | Intestinal Mucosa - metabolism | Rats, Wistar | Dinoprostone - biosynthesis | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Male | Gastric Mucosa - metabolism | Intestinal Mucosa - drug effects | Stomach Ulcer - enzymology | Arthritis, Experimental - metabolism | Intestine, Small - enzymology | Naproxen - pharmacokinetics | Intestinal Mucosa - enzymology | Gastric Mucosa - drug effects | Blood Pressure - drug effects | Molecular Structure | Hypertension - enzymology | Naproxen - analysis | Naproxen - adverse effects | Stomach Ulcer - metabolism | Gastric Mucosa - enzymology | Stomach Ulcer - drug therapy | Rats | Naproxen - therapeutic use | Hypertension - metabolism | Naproxen - chemistry | Animals | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Intestine, Small - drug effects | Cyclooxygenase 2 - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacokinetics | Mice | Arthritis, Experimental - enzymology | Cyclooxygenase 1 - metabolism | Intestine, Small - metabolism | Toxicity | Rodents | Ulcers | Research Papers
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 07/2017, Volume 102, Issue 1, pp. 52 - 61
Journal Article
Archives of Toxicology, ISSN 0340-5761, 9/2014, Volume 88, Issue 9, pp. 1635 - 1644
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 7, pp. 1649 - 1658
Journal Article
Journal of immunology (Baltimore, Md, ISSN 0022-1767, 2011, Volume 186, Issue 4, pp. 1934 - 1942
Journal Article
PLoS ONE, ISSN 1932-6203, 01/2014, Volume 9, Issue 1, p. e85254
A functional mucus layer is a key requirement for gastrointestinal health as it serves as a barrier against bacterial invasion and subsequent inflammation.... 
CELLS | EXTRACTION | BACTERIA | MUCIN | DNA | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | GUT MICROBIOTA | GERM-FREE | EXPRESSION | IRRITABLE-BOWEL-SYNDROME | Dextran Sulfate | Mucus - enzymology | Male | Intestines - immunology | Galactosemias - genetics | Intestinal Mucosa - immunology | Colitis - chemically induced | Intestinal Mucosa - enzymology | Bacteria - classification | Female | Colitis - immunology | Galactosemias - enzymology | Intestines - pathology | Microbiota - immunology | Galactosemias - immunology | Organ Size | Glycosylation | Intestinal Mucosa - microbiology | Mice, Knockout | Mucus - microbiology | Polysaccharides - metabolism | Galactosemias - microbiology | Animals | Colitis - enzymology | Colitis - microbiology | Intestines - microbiology | Mice | Mucus - immunology | Intestinal Mucosa - pathology | Intestines - enzymology | Physiological aspects | Polysaccharides | Inflammation | Colitis | Microbiota (Symbiotic organisms) | Gastrointestinal system | Disease | Laboratories | Core loss | Epithelial cells | Homeostasis | Mucus | Biochemistry | Biology | Sodium sulfates | Small intestine | Microbiota | Microorganisms | Intestine | Rodents | Gastroenterology | Bacteria | Colon | Digestive tract | Elongation | Antigens | Architecture | Digestive system | Muscles | Gastrointestinal tract | Metabolism | Ileum | Glycan | Inflammatory bowel disease | Dextran | Sodium | Crypts | Morphology | Irritable bowel syndrome | Clinical medicine | Other Basic Medicine | pathology | genetics | immunology | Intestinal Mucosa | Intestines | chemically induced | Galactosemias | microbiology | classification | enzymology | Knockout | Annan medicinsk grundvetenskap | metabolism
Journal Article
Gastroenterology, ISSN 0016-5085, 2010, Volume 139, Issue 3, pp. 869 - 881.e9
Background & Aims Mechanisms responsible for crypt architectural distortion in chronic ulcerative colitis (CUC) are not well understood. Data indicate that... 
Gastroenterology and Hepatology | Intestinal Progenitor Cells | PI3K | Pik3r1 | Intestinal Stem Cells | ULCERATIVE-COLITIS | SELF-RENEWAL | COLORECTAL-CARCINOMA | IDENTIFICATION | INTERLEUKIN-10-DEFICIENT MICE | CANCER | INFLAMMATORY-BOWEL-DISEASE | PATHWAY | GENE-EXPRESSION | WNT | GASTROENTEROLOGY & HEPATOLOGY | Stem Cells - immunology | Colon - enzymology | Phosphorylation | Cell Proliferation | T-Lymphocytes - enzymology | Colitis - genetics | Humans | Colitis - complications | Colon - drug effects | Colitis - pathology | Colon - immunology | Phosphatidylinositol 3-Kinases - metabolism | Phosphatidylinositol 3-Kinases - antagonists & inhibitors | Wnt Proteins - metabolism | Intestinal Mucosa - drug effects | Phosphatidylinositol 3-Kinases - deficiency | Stem Cells - enzymology | Time Factors | Intestinal Mucosa - immunology | Colonoscopy | Intestinal Mucosa - enzymology | Colitis - immunology | Proto-Oncogene Proteins c-akt - metabolism | Disease Models, Animal | Interleukin-10 - deficiency | Colon - pathology | Mice, Inbred C57BL | beta Catenin - metabolism | Mice, Knockout | Phosphatidylinositol 3-Kinases - genetics | Animals | Colitis - enzymology | Signal Transduction - drug effects | Biopsy | Colonic Neoplasms - pathology | Interleukin-10 - genetics | Stem Cells - drug effects | Stem Cells - pathology | T-Lymphocytes - immunology | Colonic Neoplasms - enzymology | Mice | Protein Kinase Inhibitors - pharmacology | Intestinal Mucosa - pathology
Journal Article