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Gut, ISSN 0017-5749, 11/2013, Volume 62, Issue 11, pp. 1556 - 1565
Objective Through genome-wide association scans and meta-analyses thereof, over 70 genetic loci (Crohn's disease (CD) single nucleotide polymorphisms (SNPs))... 
POPULATION | IBD - Genetics | VARIANTS | RISK | CLASSIFICATION | IBD | NOD2 | NATURAL-HISTORY | Genetic Polymorphisms | Crohn's Disease | INFLAMMATORY-BOWEL-DISEASE | FRAMESHIFT MUTATION | CARD15 | Inflammatory Bowel Disease | GASTROENTEROLOGY & HEPATOLOGY | GENOME-WIDE ASSOCIATION | Crohn Disease - epidemiology | Intestinal Obstruction - epidemiology | Crohn Disease - genetics | Prognosis | Colitis - genetics | Humans | Immunosuppressive Agents - therapeutic use | Male | Nod2 Signaling Adaptor Protein - genetics | Intestinal Obstruction - prevention & control | Colitis - epidemiology | Crohn Disease - complications | Young Adult | Ileitis - epidemiology | Adult | Female | Retrospective Studies | Intestinal Obstruction - etiology | Genetic Predisposition to Disease | Genome-Wide Association Study | Janus Kinase 2 - genetics | Europe - epidemiology | Models, Statistical | Disease Progression | Crohn Disease - therapy | Phenotype | Adolescent | Ileitis - genetics | Polymorphism, Single Nucleotide | Genotyping Techniques - methods | Intestinal Obstruction - genetics | Influence | Genome-wide association studies | Usage | Crohn's disease | Genetic aspects | Single nucleotide polymorphisms | Inflammatory bowel disease | Studies | Genotype & phenotype | Hospitals | Surgery | Gastroenterology | Genomes | Genetic testing | Deoxyribonucleic acid--DNA | Smoking | Crohns disease
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 4, pp. 771 - 782.e11
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 21, pp. 8253 - 8258
Autophagy is a lysosome-dependent degradative process that protects cancer cells from multiple stresses. In preclinical models, autophagy inhibition with... 
Cell death | Medical treatment | Cell lines | Lysosomes | Immunoblotting | Cytotoxicity | Dosage | Heterologous transplantation | Tumors | Cancer | Antimalarials | Cancer cell survival | Stress responses | Drug resistance | BISQUINOLINES | cancer cell survival | PROTEIN | cell death | MULTIDISCIPLINARY SCIENCES | TARGETING AUTOPHAGY | MOUSE | antimalarials | TUMOR | CELL-SURVIVAL | stress responses | NECROSIS | drug resistance | CYTOTOXICITY | Autophagy-Related Proteins | Colonic Neoplasms - genetics | Adenocarcinoma - pathology | Aminoquinolines - chemical synthesis | Antineoplastic Agents - chemical synthesis | Colonic Neoplasms - drug therapy | Humans | Brain Neoplasms - pathology | Aminoquinolines - toxicity | Drug Resistance, Neoplasm | Polyamines - toxicity | Intestinal Obstruction - chemically induced | Autophagy - drug effects | Antineoplastic Agents - toxicity | Glioblastoma - genetics | Adenocarcinoma - genetics | Antineoplastic Agents - pharmacology | Autophagy - genetics | Cell Death - drug effects | Aminoquinolines - pharmacology | Lysosomes - drug effects | Brain Neoplasms - genetics | Brain Neoplasms - drug therapy | Adenocarcinoma - drug therapy | Antimalarials - pharmacology | HT29 Cells | Xenograft Model Antitumor Assays | Carrier Proteins - genetics | Polyamines - pharmacology | Animals | Mice, Nude | Colonic Neoplasms - pathology | Glioblastoma - pathology | Hydroxychloroquine - pharmacology | Mice | Glioblastoma - drug therapy | Intestinal Obstruction - genetics | Polyamines - chemical synthesis | Autophagy (Cytology) | Phenotype | Genetic aspects | Dosage and administration | Enzyme inhibitors | Identification and classification | Index Medicus | Biological Sciences
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2007, Volume 104, Issue 18, pp. 7699 - 7704
The signaling molecule nitric oxide (NO), first described as endothelium-derived relaxing factor (EDRF), acts as physiological activator of NO-sensitive... 
Systolic blood pressure | Aggregation | Phenotypes | Animals | Exons | Collagens | Smooth muscle | Mice | Blood pressure | Platelets | cGMP | Knockout mice | Smooth muscle relaxation | Platelet aggregation | Cardiovascular | knockout mice | ISOFORMS | PHOSPHORYLATION | SYNTHASE GENE | MULTIDISCIPLINARY SCIENCES | RELAXATION | MECHANISMS | cardiovascular | KINASE-I | platelet aggregation | smooth muscle relaxation | SMOOTH-MUSCLE | INHIBITION | HUMAN PLATELET-AGGREGATION | VASCULAR SYSTEM | Intestinal Obstruction - enzymology | Gastric Outlet Obstruction - enzymology | Receptors, Cytoplasmic and Nuclear - deficiency | Gastric Outlet Obstruction - mortality | Intestinal Obstruction - mortality | Hypertension - mortality | Gastric Outlet Obstruction - pathology | Hypertension - enzymology | Hypertension - genetics | Heart Rate | Guanylate Cyclase - metabolism | Soluble Guanylyl Cyclase | Receptors, Cytoplasmic and Nuclear - genetics | Intestinal Obstruction - pathology | Hypertension - physiopathology | Mice, Knockout | Platelet Aggregation | Guanylate Cyclase - deficiency | Gastric Outlet Obstruction - genetics | Guanylate Cyclase - genetics | Intestinal Obstruction - genetics | Nitric Oxide - metabolism | Receptors, Cytoplasmic and Nuclear - metabolism | Physiological aspects | Muscle relaxation | Rats as laboratory animals | Research | Biological Sciences
Journal Article
PLoS Genetics, ISSN 1553-7390, 2014, Volume 10, Issue 3, p. e1004258
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 08/2016, Volume 24, Issue 8, pp. 1211 - 1215
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 09/2015, Volume 23, Issue 9, pp. 1266 - 1268
Journal Article