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Nature Immunology, ISSN 1529-2908, 05/2012, Volume 13, Issue 5, pp. 449 - 456
Intestinal phagocytes transport oral antigens and promote immune tolerance, but their role in innate immune responses remains unclear. Here we found that... 
FLAGELLIN | PATTERN-RECOGNITION | NOD-LIKE RECEPTORS | ACTIVATES CASPASE-1 | MACROPHAGES | INTERLEUKIN-1-BETA | INFLAMMASOME RECEPTORS | INFECTION | NLRP3 INFLAMMASOME | SECRETION | IMMUNOLOGY | Inflammasomes - metabolism | Humans | Receptors, Interleukin-1 - genetics | Salmonella Infections - genetics | Salmonella Infections - immunology | Clonal Anergy | Caspase 1 - metabolism | Monocytes - metabolism | Monocytes - immunology | Intestines - immunology | Host-Pathogen Interactions - immunology | Signal Transduction - immunology | Calcium-Binding Proteins - immunology | Interleukin-1beta - metabolism | Tumor Necrosis Factor-alpha - immunology | Apoptosis Regulatory Proteins - genetics | Pseudomonas - immunology | Toll-Like Receptors - metabolism | Neutrophil Infiltration - immunology | Neutrophils - pathology | Apoptosis Regulatory Proteins - immunology | Flagellin - immunology | Receptors, Interleukin-1 - immunology | Mice, Inbred C57BL | Toll-Like Receptors - immunology | Neutrophils - immunology | Salmonella - genetics | Signal Transduction - genetics | Phagocytes - immunology | Neutrophil Infiltration - genetics | Mice, Knockout | Pseudomonas Infections - immunology | Salmonella - immunology | Animals | Intestines - microbiology | Phagocytes - microbiology | Inflammasomes - immunology | Interleukin-6 - immunology | Interleukin-6 - biosynthesis | Mice | Mice, Inbred BALB C | Tumor Necrosis Factor-alpha - biosynthesis | Calcium-Binding Proteins - genetics | Index Medicus
Journal Article
Nature Medicine, ISSN 1078-8956, 05/2016, Volume 22, Issue 5, pp. 516 - 523
Journal Article
Immunity, ISSN 1074-7613, 09/2014, Volume 41, Issue 3, pp. 478 - 492
Journal Article
Immunity, ISSN 1074-7613, 04/2015, Volume 42, Issue 4, pp. 744 - 755
The microbiota stimulates inflammation, but the signaling pathways and the members of the microbiota involved remain poorly understood. We found that the... 
DEXTRAN SULFATE | IMMUNE-SYSTEM | COLITIS | MACROPHAGES | MICE | INNATE LYMPHOID-CELLS | GUT MICROBIOTA | GERM-FREE | IMMUNOLOGY | PROTEUS-MIRABILIS | BOWEL-DISEASE | Receptors, CCR2 - genetics | Inflammation - pathology | Hemolysin Proteins - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Proteus Infections - genetics | Receptors, CCR2 - immunology | Hemolysin Proteins - genetics | Salmonella Infections - genetics | Antigens, Ly - genetics | Salmonella Infections - immunology | Symbiosis - immunology | Monocytes - immunology | Interleukin-1beta - genetics | Intestines - immunology | Proteus Infections - pathology | Monocytes - pathology | Carrier Proteins - immunology | Macrophages - immunology | Macrophages - microbiology | Proteus mirabilis - immunology | Monocytes - microbiology | Salmonella Infections - pathology | Inflammation - microbiology | Microbiota - immunology | Macrophages - pathology | Proteus Infections - microbiology | Signal Transduction | Mice, Inbred C57BL | Gene Expression Regulation | Intestines - injuries | Interleukin-1beta - immunology | Inflammation - immunology | Proteus Infections - immunology | Inflammasomes - genetics | Mice, Knockout | Carrier Proteins - genetics | Salmonella - immunology | Animals | Intestines - microbiology | Antigens, Ly - immunology | Inflammasomes - immunology | Inflammation - genetics | Salmonella Infections - microbiology | Mice | Index Medicus
Journal Article
Journal Article
Immunity, ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 563 - 573
Mice lacking junctional adhesion molecule A (JAM-A, encoded by ) exhibit enhanced intestinal epithelial permeability, bacterial translocation, and elevated... 
GROWTH-FACTOR-BETA | INFLAMMATORY-BOWEL-DISEASE | IMMUNOGLOBULIN-A | IN-VIVO | REGULATORY T-CELLS | JUNCTIONAL-ADHESION-MOLECULE | DEFICIENT MICE | E-CADHERIN | IMMUNOLOGY | ORAL ANTIGEN | EXPRESSION | Dextran Sulfate | Cell Adhesion Molecules - genetics | Intestinal Mucosa - metabolism | Colitis - genetics | Immunoglobulin A - genetics | Male | Homeodomain Proteins - immunology | Intestines - metabolism | Cell Adhesion Molecules - immunology | Intestines - immunology | Adaptive Immunity - genetics | CD4-Positive T-Lymphocytes - immunology | Epithelium - immunology | Flow Cytometry | Intestinal Mucosa - immunology | Colitis - chemically induced | Female | Adaptive Immunity - immunology | Colitis - immunology | Transforming Growth Factor beta - immunology | Gene Expression | Bacterial Translocation - genetics | Epithelium - metabolism | Mice, Inbred C57BL | CD4-Positive T-Lymphocytes - metabolism | Bacterial Translocation - immunology | Intestinal Mucosa - microbiology | Permeability | Reverse Transcriptase Polymerase Chain Reaction | Receptors, Cell Surface - immunology | Homeodomain Proteins - genetics | Mice, Knockout | Animals | Intestines - microbiology | Transforming Growth Factor beta - genetics | Immunoglobulin A - immunology | Mice | Transforming Growth Factor beta - metabolism | Receptors, Cell Surface - genetics | Disease susceptibility | Colitis | T cells | Transforming growth factors | Immunoglobulin A | Inflammatory bowel disease | Studies | Medical research | Nutrition research | Disease | Antibiotics | Lymphocytes | Rodents | Small intestine | Immune system | Cell adhesion & migration | Index Medicus | Medical and Health Sciences | Homeodomain Proteins/genetics/immunology | Medicin och hälsovetenskap | Cell Surface/genetics/immunology | Colitis/chemically induced/genetics/immunology | CD4-Positive T-Lymphocytes/immunology/metabolism | Bacterial Translocation/genetics/immunology | Receptors | Immunoglobulin A/genetics/immunology | Transforming Growth Factor beta/genetics/immunology/metabolism | Intestinal Mucosa/immunology/metabolism/microbiology | Adaptive Immunity/genetics/immunology | Basic Medicine | Intestines/immunology/metabolism/microbiology | Cell and Molecular Biology | Inbred C57BL | Knockout | Cell Adhesion Molecules/genetics/immunology | Epithelium/immunology/metabolism | Medicinska och farmaceutiska grundvetenskaper | Cell- och molekylärbiologi
Journal Article
European Journal of Immunology, ISSN 0014-2980, 02/2014, Volume 44, Issue 2, pp. 370 - 385
IL‐13 has been implicated in the pathogenesis of ulcerative colitis (UC), and may have a role in animal models of gut fibrosis. We studied the involvement of... 
T helper cell type 2 | Crohn's disease | Fibrosis | Ulcerative colitis | CROHNS-DISEASE | DENDRITIC CELLS | ULCERATIVE-COLITIS | INDUCTION | IMMUNOLOGY | MUCOSA | MATRIX METALLOPROTEINASES | GROWTH-FACTOR-BETA | TGF-BETA-1 PRODUCTION | EXPRESSION | T-CELLS | Inflammation - pathology | Humans | Inflammatory Bowel Diseases - immunology | Middle Aged | Interleukin-13 - immunology | Th2 Cells - immunology | Colitis, Ulcerative - immunology | Intestines - immunology | Young Adult | Transforming Growth Factor beta1 - immunology | Interleukin-13 Receptor alpha1 Subunit - immunology | Intestinal Mucosa - immunology | Inflammatory Bowel Diseases - pathology | Leukocytes, Mononuclear - immunology | Fibrosis - immunology | Adult | Macrophages - immunology | Intestines - pathology | Macrophages - pathology | CD28 Antigens - immunology | Colitis, Ulcerative - pathology | Inflammation - immunology | Crohn Disease - immunology | Leukocytes, Mononuclear - pathology | Mucous Membrane - pathology | Mucous Membrane - immunology | Crohn Disease - pathology | Interleukin-13 Receptor alpha2 Subunit - immunology | Interferon-gamma - immunology | Adolescent | CD3 Complex - immunology | Aged | Fibrosis - pathology | Intestinal Mucosa - pathology | Natural Killer T-Cells - immunology | Interleukins | T cells | Intermediate filament proteins | Analysis | Collagen | Inflammatory bowel disease | Rodents | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 09/2012, Volume 37, Issue 3, pp. 463 - 474
Natural helper (NH) cells are innate lymphoid cells (ILCs) that produce T helper-2 (Th2)-cell-type cytokines in the lung- and gut-associated lymphoid tissues.... 
PROGENITORS | CYTOKINES | ROR-GAMMA-T | BONE-MARROW | TYPE-2 IMMUNITY | MICE | INNATE LYMPHOID-CELLS | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | Antigens, Ly - genetics | Male | Th2 Cells - immunology | Proto-Oncogene Proteins c-kit - immunology | Interleukin Receptor Common gamma Subunit - immunology | Flow Cytometry | Lymphocytes - immunology | Allergens - immunology | T-Lymphocytes, Helper-Inducer - immunology | Bone Marrow Cells - immunology | Bone Marrow Transplantation | Pneumonia - immunology | Female | Papain - immunology | Proto-Oncogene Proteins c-kit - genetics | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Pneumonia - genetics | Lymphocytes - metabolism | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Nuclear Receptor Subfamily 1, Group F, Member 1 - immunology | T-Lymphocytes, Helper-Inducer - metabolism | Membrane Proteins - genetics | Mice, Inbred C57BL | Cells, Cultured | Membrane Proteins - immunology | Mice, SCID | Interleukin Receptor Common gamma Subunit - genetics | Th2 Cells - metabolism | Mice, Knockout | Animals | Antigens, Ly - immunology | Mice, Inbred NOD | Mice | Nuclear Receptor Subfamily 1, Group F, Member 1 - genetics | Bone Marrow Cells - metabolism | Cell Lineage - immunology | Allergens | Proteases | Lymphocytes | Oncology, Experimental | Bone marrow | Transplantation | Inflammation | Research | Cancer | Medical research | Lungs | Cytokines | Rodents | Gene expression | Small intestine | Experiments | Index Medicus
Journal Article