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Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 10/2016, Volume 60, Issue 10, pp. 6115 - 6120
Hypervirulent Klebsiella pneumoniae (hvKP) is traditionally defined by hypermucoviscosity, but data based on genetic background are limited.... 
STRAINS | AEROBACTIN | VIRULENCE ANALYSIS | TAIWAN | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | SPECTRUM BETA-LACTAMASES | HONG-KONG | EMERGENCE | PYOGENIC LIVER-ABSCESS | Diabetes Mellitus - pathology | Prevalence | Prospective Studies | Klebsiella Infections - pathology | Humans | Middle Aged | Virulence | Male | Klebsiella pneumoniae - classification | Phylogeny | Multilocus Sequence Typing | Cross Infection - pathology | beta-Lactamases - genetics | Pneumonia, Bacterial - pathology | Gene Expression | Pneumonia, Bacterial - complications | Plasmids - metabolism | Cross Infection - microbiology | Diabetes Mellitus - epidemiology | Plasmids - chemistry | Bacteremia - epidemiology | Bacteremia - pathology | Neoplasms - epidemiology | Intraabdominal Infections - complications | Klebsiella pneumoniae - isolation & purification | Diabetes Complications | Cross Infection - complications | Bacteremia - microbiology | Neoplasms - complications | Klebsiella Infections - epidemiology | Klebsiella pneumoniae - genetics | Adult | Female | beta-Lactamases - metabolism | Cross Infection - epidemiology | Pneumonia, Bacterial - microbiology | Intraabdominal Infections - microbiology | Neoplasms - microbiology | Phylogeography | Bacteremia - complications | Bacterial Proteins - genetics | Serogroup | Klebsiella Infections - complications | Pneumonia, Bacterial - epidemiology | China - epidemiology | Klebsiella Infections - microbiology | Intraabdominal Infections - epidemiology | Diabetes Mellitus - microbiology | Intraabdominal Infections - pathology | Klebsiella pneumoniae - pathogenicity | Bacterial Proteins - metabolism | Aged | Neoplasms - pathology | Index Medicus
Journal Article
Antimicrobial Agents and Chemotherapy, ISSN 0066-4804, 04/2016, Volume 60, Issue 4, pp. 2443 - 2449
Nephrotoxicity is the main adverse effect of colistin and polymyxin B (PMB). It is not clear whether these two antibiotics are associated with different... 
HOSPITAL MORTALITY | ACUTE KIDNEY INJURY | GRAM-NEGATIVE BACTERIA | RISK-FACTORS | CARE MEDICAL-CENTER | POPULATION PHARMACOKINETICS | MICROBIOLOGY | PHARMACOLOGY & PHARMACY | INTRAVENOUS COLISTIN | CRITICALLY-ILL PATIENTS | METHANESULFONATE | NEPHROTOXICITY | Kidney Failure, Chronic - mortality | Multivariate Analysis | Polymyxin B - administration & dosage | Body Weight | Prospective Studies | Age Factors | Humans | Middle Aged | Male | Gram-Negative Bacterial Infections - microbiology | Respiratory Tract Infections - microbiology | Respiratory Tract Infections - mortality | Kidney Failure, Chronic - pathology | Kidney Failure, Chronic - chemically induced | Aged, 80 and over | Adult | Female | Acute Kidney Injury - chemically induced | Anti-Bacterial Agents - adverse effects | Colistin - adverse effects | Respiratory Tract Infections - pathology | Intensive Care Units | Gram-Negative Bacterial Infections - pathology | Drug Administration Schedule | Acute Kidney Injury - drug therapy | Acute Kidney Injury - pathology | Colistin - analogs & derivatives | Intraabdominal Infections - microbiology | Polymyxin B - adverse effects | Kidney Failure, Chronic - drug therapy | Risk Factors | Colistin - administration & dosage | Gram-Negative Bacterial Infections - drug therapy | Respiratory Tract Infections - drug therapy | Intraabdominal Infections - mortality | Gram-Negative Bacteria - drug effects | Acute Kidney Injury - mortality | Intraabdominal Infections - pathology | Gram-Negative Bacteria - growth & development | Gram-Negative Bacteria - pathogenicity | Survival Analysis | Aged | Anti-Bacterial Agents - administration & dosage | Intraabdominal Infections - drug therapy | Gram-Negative Bacterial Infections - mortality | Index Medicus
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167522 - e0167522
In this study, we retrospectively reviewed the clinical experience of patients receiving doripenem-containing regimens for the treatment of... 
IN-VITRO | MULTICENTER | BACTERIAL-INFECTIONS | IMIPENEM-CILASTATIN | EFFICACY | VENTILATOR-ASSOCIATED PNEUMONIA | SAFETY | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | SURVEILLANCE | ANTIMICROBIAL ACTIVITY | Soft Tissue Infections - mortality | Urinary Tract Infections - mortality | Humans | Middle Aged | Cross Infection - mortality | Male | Tertiary Care Centers - statistics & numerical data | Hospital Mortality - trends | Respiratory Tract Infections - microbiology | Anti-Bacterial Agents - therapeutic use | Cross Infection - pathology | Respiratory Tract Infections - mortality | Soft Tissue Infections - pathology | Aged, 80 and over | Female | Urinary Tract Infections - microbiology | Urinary Tract Infections - pathology | Retrospective Studies | Soft Tissue Infections - drug therapy | Respiratory Tract Infections - pathology | Intraabdominal Infections - microbiology | Respiratory Tract Infections - drug therapy | Treatment Outcome | Cross Infection - drug therapy | Urinary Tract Infections - drug therapy | Intraabdominal Infections - mortality | Intraabdominal Infections - pathology | Soft Tissue Infections - microbiology | Carbapenems - therapeutic use | Cross Infection - microbiology | Aged | Intraabdominal Infections - drug therapy | APACHE | Infection | Doripenem | Care and treatment | Dosage and administration | Health care | Therapy | Pneumonia | Intensive care | Medical services | Medical records | Infections | Urinary tract | Drug resistance | Respiratory tract | Respiratory tract diseases | Urinary tract infections | Urogenital system | Pathogens | Ventilators | Medical research | Statistical analysis | Bacterial infections | Review boards | Mortality | Antimicrobial agents | Patients | Abdomen | Urinary tract diseases | Medicine | Studies | Hospitals | Antibiotics | Pharmacy | Skin | Adults | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0127126 - e0127126
Background There are limited data describing the clinical characteristics of pyogenic spondylitis caused by Gram-negative bacteria (GNB). The aim of this study... 
DIAGNOSIS | MANAGEMENT | MULTIDISCIPLINARY SCIENCES | HEMATOGENOUS VERTEBRAL OSTEOMYELITIS | OUTCOMES | SPONDYLODISCITIS | EPIDEMIOLOGY | Sepsis - etiology | Cross Infection - etiology | Humans | Middle Aged | Male | Gram-Negative Bacterial Infections - microbiology | Cross Infection - pathology | Sepsis - pathology | Spondylitis - microbiology | Intraabdominal Infections - etiology | Spondylitis - pathology | Female | Retrospective Studies | Gram-Negative Bacterial Infections - pathology | Tertiary Care Centers | Intraabdominal Infections - microbiology | Risk Factors | Treatment Outcome | Gram-Positive Cocci - pathogenicity | Intraabdominal Infections - pathology | Cross Infection - microbiology | Gram-Negative Bacteria - pathogenicity | Spondylitis - etiology | Aged | Gram-Negative Bacterial Infections - etiology | Sepsis - microbiology | Complications and side effects | Spondylitis | Medical research | Gram-negative bacterial infections | Gram-positive bacterial infections | Medicine, Experimental | Comparative analysis | Risk factors | Laboratories | Physicians | Escherichia coli | Medical records | Infections | Arthritis | Epidemiology | Blood | Medical schools | Clinical outcomes | Pain | Etiology | Quality | Bacteria | Pseudomonas aeruginosa | Cocci | Trends | Gram-negative bacteria | Gram-positive cocci | Internal medicine | Mortality | Intra-abdominal infection | Risk analysis | Patients | Genitourinary tract | Medicine | Studies | Infectious diseases | Hospitals | Antibiotics | Sepsis | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2015, Volume 10, Issue 9, pp. e0137262 - e0137262
Rationale Experimental studies suggest that intra-abdominal infection (IAI) induces biological alterations that may affect the risk of lung infection.... 
MORTALITY | BACTERIAL CLEARANCE | PSEUDOMONAS-AERUGINOSA | MULTIDISCIPLINARY SCIENCES | ANIMAL-MODELS | LIPOPOLYSACCHARIDE | ENDOTOXIN-TOLERANCE | LUNG INJURY | STAPHYLOCOCCUS-AUREUS | ORGAN FAILURE | HUMAN MONOCYTES | Pneumonia, Ventilator-Associated - mortality | Prospective Studies | Humans | Middle Aged | Pseudomonas aeruginosa - growth & development | Male | Bacterial Infections - complications | Female | Bacterial Infections - microbiology | Enterobacteriaceae - growth & development | Databases, Factual | Length of Stay | Shock, Septic - pathology | Intensive Care Units | Intraabdominal Infections - microbiology | Risk Factors | Shock, Septic - complications | Shock, Septic - mortality | Respiration, Artificial | Intraabdominal Infections - mortality | Shock, Septic - microbiology | Intraabdominal Infections - pathology | Pneumonia, Ventilator-Associated - microbiology | Bacterial Infections - pathology | Pneumonia, Ventilator-Associated - complications | Survival Analysis | Aged | Pneumonia, Ventilator-Associated - pathology | Staphylococcus aureus - growth & development | Bacterial Infections - mortality | Intraabdominal Infections - complications | Complications and side effects | Sepsis | Ventilator-associated pneumonia | Prognosis | Research | Risk factors | Pneumonia | Intensive care | Laboratories | Lung | Infections | Data bases | Confidence intervals | Databases | Rodents | Surgery | Pseudomonas aeruginosa | Physiology | Nosocomial infections | Teaching hospitals | Ventilators | Bacterial infections | Mortality | Pancreatitis | Health risks | Intra-abdominal infection | Septic shock | Risk analysis | Patients | Abdomen | Ventilation | Index Medicus
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 2014, Volume 44, Issue 3, pp. 222 - 228
Journal Article
International Journal of Antimicrobial Agents, ISSN 0924-8579, 10/2018, Volume 52, Issue 4, pp. 506 - 509
Journal Article
Clinical Microbiology and Infection, ISSN 1198-743X, 07/2013, Volume 19, Issue 7, pp. 634 - 639
Journal Article
Journal of Nanobiotechnology, ISSN 1477-3155, 10/2015, Volume 13, Issue 1, pp. 75 - 75
Journal Article