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2002, Molecular biology intelligence unit (Unnumbered), ISBN 0306474395, Volume 23, 174
Book
1997, Cancer surveys, ISBN 0879695188, Volume 29., vi, 363
Book
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2012, Volume 7, Issue 5, pp. e36616 - e36616
Mammalian Target of Rapamycin Complex 1 (mTORC1) is activated by growth factor-regulated phosphoinositide 3-kinase (PI3K)/Akt/Rheb signalling and extracellular... 
PROMOTES CELL-GROWTH | DROSOPHILA-MELANOGASTER | BODY-SIZE | MULTIDISCIPLINARY SCIENCES | TUMOR-SUPPRESSOR | AUTOPHAGY | IDENTIFICATION | VACUOLAR H+-ATPASE | SLC36 FAMILY | CANCER-THERAPY | MTOR | Humans | Multiprotein Complexes | Ras Homolog Enriched in Brain Protein | Phosphatidylinositol 3-Kinases - metabolism | Amino Acids - pharmacology | Endosomes - metabolism | Mechanistic Target of Rapamycin Complex 1 | Drosophila melanogaster - metabolism | Lysosomes - metabolism | Protein Binding - drug effects | Endosomes - drug effects | HEK293 Cells | Female | Proto-Oncogene Proteins c-akt - metabolism | Lysosomes - drug effects | Endocytosis - drug effects | Drosophila melanogaster - cytology | Neuropeptides - metabolism | Amino Acid Transport Systems - metabolism | Symporters - metabolism | Animals | GTP Phosphohydrolases - metabolism | Proteins - metabolism | Monomeric GTP-Binding Proteins - metabolism | Signal Transduction - drug effects | Drosophila melanogaster - growth & development | Intracellular Membranes - drug effects | TOR Serine-Threonine Kinases | Intracellular Membranes - metabolism | Type 2 diabetes | Amino acids | G proteins | Cells | Adenosine triphosphatase | TOR protein | Cell culture | Membranes | Disease | Genes | Acidification | Lysosomes | Intracellular signalling | AKT protein | Activation | Kinases | Autophagy | Cell surface | Proteins | Endocytosis | Compartments | Cell cycle | Genetics | Physiology | Localization | Growth factors | H+-transporting ATPase | Translocation | Intracellular levels | Drosophila | Rapamycin | Anatomy & physiology | Mammals | 1-Phosphatidylinositol 3-kinase | Insects | In vivo methods and tests | Intracellular | Transporter | Cancer | Endosomes | Kidney transplantation | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 2013, Volume 499, Issue 7456, pp. 50 - 54
53BP1 (also called TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand-break (DSB) repair by... 
CRB2 | RECRUITMENT | FISSION YEAST | METHYLATION | CHROMATIN | DEPENDENT RESPONSE | RESECTION | MULTIDISCIPLINARY SCIENCES | SITES | DOUBLE-STRAND BREAKS | CLASS-SWITCH RECOMBINATION | Schizosaccharomyces pombe Proteins - chemistry | Histones - chemistry | Nucleosomes - chemistry | Humans | Ubiquitin - metabolism | Molecular Sequence Data | Male | Intracellular Signaling Peptides and Proteins - metabolism | DNA Breaks, Double-Stranded | DNA-Binding Proteins - deficiency | Cell Cycle Proteins - chemistry | Intracellular Signaling Peptides and Proteins - deficiency | Ubiquitination | Schizosaccharomyces pombe Proteins - metabolism | Female | Lysine - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Schizosaccharomyces | Protein Structure, Tertiary | Amino Acid Sequence | Cell Line | Signal Transduction | Cell Cycle Proteins - metabolism | Nucleosomes - metabolism | Mutant Proteins - metabolism | Nuclear Proteins - metabolism | DNA-Binding Proteins - genetics | Nuclear Proteins - chemistry | DNA-Binding Proteins - chemistry | Chromosomal Proteins, Non-Histone - deficiency | Amino Acid Motifs | Chromosomal Proteins, Non-Histone - genetics | Animals | Intracellular Signaling Peptides and Proteins - chemistry | Mutant Proteins - chemistry | Protein Binding | Mice | DNA Damage | Histones - metabolism | Tumor Suppressor p53-Binding Protein 1 | Chromosomal Proteins, Non-Histone - chemistry | Ubiquitin | Research | Properties | DNA repair | DNA damage | Proteins | DNA methylation | Mutation | Experiments | Recruitment | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2007, Volume 104, Issue 16, pp. 6519 - 6526
Two classes of sterols, cholesterol and oxysterols, block export of sterol regulatory element-binding proteins (SREBPs) from the endoplasmic reticulum (ER) to... 
Transfection | Sterols | Plasmids | Cell lines | Antibodies | Amino acids | Cell membranes | CHO cells | Cholesterols | P branes | COPII vesicles | Cholesterol homeostasis | Oxysterols | SREBP pathway | COAT | cholesterol homeostasis | COENZYME-A REDUCTASE | CHOLESTEROL | oxysterols | MULTIDISCIPLINARY SCIENCES | CLEAVAGE-ACTIVATING PROTEIN | INHIBITION | ER MEMBRANES | HAMSTER OVARY CELLS | SENSING DOMAIN | BINDING | VESICLE | Protein Sorting Signals - physiology | Cricetulus | Vesicular Transport Proteins - metabolism | Humans | Endoplasmic Reticulum - metabolism | Molecular Sequence Data | Intracellular Signaling Peptides and Proteins - immunology | Protein Transport - physiology | Antibodies, Blocking - pharmacology | Intracellular Signaling Peptides and Proteins - metabolism | Intracellular Signaling Peptides and Proteins - deficiency | Vesicular Transport Proteins - antagonists & inhibitors | Clone Cells | Membrane Proteins - metabolism | Intracellular Signaling Peptides and Proteins - genetics | CHO Cells | Amino Acid Sequence | Cricetinae | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | COP-Coated Vesicles - metabolism | Membrane Proteins - immunology | Sterol Regulatory Element Binding Proteins - metabolism | Animals | Membrane Proteins - antagonists & inhibitors | Golgi Apparatus - metabolism | Intracellular Signaling Peptides and Proteins - physiology | Homeostasis | Research | Endoplasmic reticulum | Proteins | Membranes | Biochemistry | Mutation | Experiments | Binding sites | Cholesterol | Cells | Index Medicus | Biological Sciences
Journal Article
Detection of Intracytoplasmic Cytokines by Flow Cytometry, 12/2000
Flow cytometry has been used as a powerful technique for studying cell surface antigen expression as well as intracellular molecules. Its capability of... 
intracellular cytokines, flow cytometry, leishmaniasis
Journal
Nature, ISSN 0028-0836, 05/2009, Volume 459, Issue 7245, pp. 433 - 436
Fungal infections represent a serious threat, particularly in immunocompromised patients. Interleukin-1 (IL-1 ) is a key pro-inflammatory factor in innate... 
RHEUMATOID-ARTHRITIS | CELLS | ACTIVATION | CANDIDA-ALBICANS | TYROSINE KINASE | MULTIDISCIPLINARY SCIENCES | INNATE IMMUNE-RESPONSE | RECEPTOR | MICE | INHIBITOR | NALP3 INFLAMMASOME | Potassium - metabolism | Reactive Oxygen Species - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein | Protein-Tyrosine Kinases - metabolism | Humans | Caspase 1 - metabolism | Monocytes - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Protein-Tyrosine Kinases - deficiency | Intracellular Signaling Peptides and Proteins - deficiency | Protein-Tyrosine Kinases - genetics | Candida albicans - physiology | Interleukin-1beta - biosynthesis | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Carrier Proteins - immunology | Signal Transduction | Intracellular Signaling Peptides and Proteins - antagonists & inhibitors | Interleukin-1beta - immunology | Inflammation - immunology | Candida albicans - immunology | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Mice | Nigericin - pharmacology | Enzyme Activation | Protein-Tyrosine Kinases - antagonists & inhibitors | Mycoses | Research | Properties | Phosphotransferases | Cellular control mechanisms | Proteins | Studies | Fungi | E coli | Research & development--R&D | Clinical trials | Pattern recognition | Kinases | Cells | Index Medicus
Journal Article
Science, ISSN 0036-8075, 2/2009, Volume 323, Issue 5917, pp. 1057 - 1060
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2018, Volume 13, Issue 12, pp. e0208526 - e0208526
Journal Article
Molecular Cell, ISSN 1097-2765, 08/2017, Volume 67, Issue 3, pp. 387 - 399.e5
The DNA-mediated innate immune response underpins anti-microbial defenses and certain autoimmune diseases. Here we used immunoprecipitation, mass spectrometry,... 
HEXIM1 | DNA-PK | innate immune response |