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1. Full Text Myofilament Ca Sensitization Increases Cytosolic Ca Binding Affinity, Alters Intracellular Ca Homeostasis, and Causes Pause-Dependent Ca-Triggered Arrhythmia
by Schober, Tilmann and Huke, Sabine and Venkataraman, Raghav and Gryshchenko, Oleksiy and Kryshtal, Dmytro and Hwang, Hyun Seok and Baudenbacher, Franz J and Knollmann, Björn C
Circulation Research, ISSN 0009-7330, 07/2012, Volume 111, Issue 2, pp. 170 - 179
RATIONALE:Ca binding to the troponin complex represents a major portion of cytosolic Ca buffering. Troponin mutations that increase myofilament Ca sensitivity... 
early afterdepolarizations | familial hypertrophic cardiomyopathy | myofilament Ca sensitivity | arrhythmia | Ca buffering | CARDIAC & CARDIOVASCULAR SYSTEMS | SUDDEN-DEATH | SARCOPLASMIC-RETICULUM | INTACT MOUSE HEART | TORSADE-DE-POINTES | CARDIAC TROPONIN-T | PERIPHERAL VASCULAR DISEASE | LONG QT SYNDROME | RAT VENTRICULAR MYOCYTES | HEMATOLOGY | MUSCLE-CONTRACTION | TRANSGENIC MICE | Arrhythmias, Cardiac - metabolism | Protein Binding - genetics | Action Potentials - genetics | Calcium - metabolism | Humans | Mice, Transgenic | Myofibrils - genetics | Up-Regulation - genetics | Arrhythmias, Cardiac - physiopathology | Animals | Calcium - physiology | Cytosol - metabolism | Mice | Myofibrils - metabolism | Mutation | Calcium Signaling - genetics | Cytosol - pathology | Arrhythmias, Cardiac - genetics | Homeostasis - genetics | Intracellular Fluid - metabolism | Index Medicus
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2. Full Text Balanced changes in Ca buffering by SERCA and troponin contribute to Ca handling during β-adrenergic stimulation in cardiac myocytes
by Briston, Sarah J and Dibb, Katharine M and Solaro, R. John and Eisner, David A and Trafford, Andrew W
Cardiovascular Research, ISSN 0008-6363, 11/2014, Volume 104, Issue 2, pp. 347 - 354
During activation of cardiac myocytes, less than 1% of cytosolic Ca is free; the rest is bound to buffers, largely SERCA, and troponin C. Signalling by... 
Troponin | Phospholamban | Calcium | SERCA | Buffering | CARDIAC & CARDIOVASCULAR SYSTEMS | THIN-FILAMENTS | PROTEIN-KINASE | WAVE CHARACTERISTICS | SARCOPLASMIC-RETICULUM | TIME-COURSE | INTRACELLULAR CA2 | SYSTOLIC CA2 | RAT VENTRICULAR MYOCYTES | CALCIUM CONTENT | TRANSIENT | Phosphorylation | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Calcium - metabolism | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Adrenergic beta-Agonists - pharmacology | Calcium-Binding Proteins - deficiency | Mice, Knockout | Myocytes, Cardiac - enzymology | Animals | Myocytes, Cardiac - drug effects | Time Factors | Calcium Signaling - drug effects | Troponin I - genetics | Isoproterenol - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - antagonists & inhibitors | Troponin I - metabolism | Calcium-Binding Proteins - genetics | Index Medicus | Original
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3. Full Text Membrane potential determines calcium alternans through modulation of SR Ca 2 + load and L-type Ca 2 + current
by Kanaporis, Giedrius and Blatter, Lothar A
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2017, Volume 105, pp. 49 - 58
Abstract Alternans is a risk factor for cardiac arrhythmia, including atrial fibrillation. At the cellular level alternans is observed as beat-to-beat... 
Cardiovascular | Rabbits | Animals | Membrane Potentials | Calcium - metabolism | Intracellular Space - metabolism | Myocytes, Cardiac - metabolism | Sarcoplasmic Reticulum - metabolism | Calcium Channels, L-Type - metabolism | Calcium Signaling | Heart Atria - metabolism
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4. Full Text Ca-dependent facilitation of cardiac Ca current is due to Ca-calmodulin- dependent protein kinase
by Yuan, W and Bers, D.M
American Journal of Physiology - Heart and Circulatory Physiology, ISSN 0363-6135, 1994, Volume 267, Issue 3, pp. H982 - H993
Repetitive membrane potential (E(m)) depolarization from -90 to 0 mV in rabbit and ferret ventricular myocytes induces a facilitation or ''staircase'' of Ca... 
calcium-calmodulin- dependent protein kinase | staurosporine | KN-62 | staircase | cardiac myocyte | H-89 | PHYSIOLOGY | CHROMAFFIN CELLS | STAUROSPORINE | STAIRCASE | PHOSPHORYLATION | INTRACELLULAR CALCIUM | CALCIUM CHANNELS | CARDIAC MYOCYTE | REPETITIVE DEPOLARIZATION | CA-2+ CURRENT | MAMMALIAN HEART-CELLS | CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE | POTENTIATION | RABBIT VENTRICULAR MYOCYTES | K UM PHYSIOLOGY | GUINEA-PIG MYOCYTES | Calcium-Calmodulin-Dependent Protein Kinases - physiology | Rabbits | Alkaloids - pharmacology | Staurosporine | Heart - physiology | 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine - analogs & derivatives | Peptide Fragments - pharmacology | Electric Conductivity | Calcium-Calmodulin-Dependent Protein Kinases - antagonists & inhibitors | Ferrets | Piperazines - pharmacology | Adenosine Triphosphate - analogs & derivatives | Myocardium - cytology | Adenosine Triphosphate - pharmacology | Heart Ventricles | Animals | Calcium - physiology | Isoquinolines - pharmacology | Sulfonamides | Calcium-Calmodulin-Dependent Protein Kinases - pharmacology | Heart | Physiological aspects | Calcium channels | Research | Protein kinases | Index Medicus
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5. Full Text Biphasic decay of the Ca transient results from increased sarcoplasmic reticulum Ca leak
by Sankaranarayanan, Rajiv and Li, Yatong and Greensmith, David J and Eisner, David A and Venetucci, Luigi
The Journal of Physiology, ISSN 0022-3751, 02/2016, Volume 594, Issue 3, pp. 611 - 623
Ca leak from the sarcoplasmic reticulum through the ryanodine receptor (RyR) reduces the amplitude of the Ca transient and slows its rate of decay. In the... 
PHYSIOLOGY | STAGE HEART-FAILURE | SYSTOLIC CA2 | RYANODINE RECEPTOR | INTRACELLULAR CALCIUM | TACHYCARDIA | RAT VENTRICULAR MYOCYTES | RECEPTOR OPEN PROBABILITY | CARDIAC CALCIUM-RELEASE | EXPRESSION | NEUROSCIENCES | SPARKS | Rats, Wistar | Adrenergic beta-Agonists - pharmacology | Sarcoplasmic Reticulum - physiology | Male | Tetracaine - pharmacology | Calcium Channel Blockers - pharmacology | Animals | Calcium - physiology | Myocytes, Cardiac - physiology | Isoproterenol - pharmacology | Caffeine - pharmacology | Thapsigargin - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - antagonists & inhibitors | Ryanodine - pharmacology | Ryanodine Receptor Calcium Release Channel - physiology | Caffeine | Index Medicus | Cardiovascular Physiology | Research Paper | Cardiovascular | Cellular and molecular Physiology
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6. Full Text Intracellular Ca-carbonate biomineralization is widespread in cyanobacteria
by Karim Benzerara and Feriel Skouri-Panet and Jinhua Li and Céline Férard and Muriel Gugger and Thierry Laurent and Estelle Couradeau and Marie Ragon and Julie Cosmidis and Nicolas Menguy and Isabel Margaret-Oliver and Rosaluz Tavera and Purificación López-García and David Moreira
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2014, Volume 111, Issue 30, pp. 10933 - 10938
Cyanobacteria have played a significant role in the formation of past and modern carbonate deposits at the surface of the Earth using a biomineralization... 
Biomineralogy | Inclusion bodies | Cyanobacteria | Phylogenetics | Evolution | Bacteria | Carbonates | Cytoplasmic inclusions | Cytoplasm | Daughter cells | Calcification | Amorphous calcium carbonate | Polyphosphate | polyphosphate | PRECIPITATION | MULTIDISCIPLINARY SCIENCES | SYNECHOCOCCUS STRAINS | ESCHERICHIA-COLI | MINERALIZATION | MECHANISMS | calcification | amorphous calcium carbonate | PHOTOSYNTHESIS | FIXATION | CALCIUM-CARBONATE | Cyanobacteria - genetics | Inclusion Bodies - genetics | Cyanobacteria - classification | Base Sequence | Cyanobacteria - metabolism | Molecular Sequence Data | Cytoplasm - metabolism | Cytoplasm - genetics | Calcium Carbonate - metabolism | Inclusion Bodies - metabolism | Microbiological research | Physiological aspects | Biomineralization | Research | Properties | Mineralization | Cells | Index Medicus | Life Sciences | Microbiology and Parasitology | Earth Sciences | Sciences of the Universe | Biological Sciences | Physical Sciences
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7. Full Text Impact of janus kinase 3 on cellular Ca 2+ release, store operated Ca 2+ entry and Na + /Ca 2+ exchanger activity in dendritic cells
by Yan, Jing and Schmid, Evi and Hosseinzadeh, Zohreh and Honisch, Sabina and Shumilina, Ekaterina and Fuchs, Joerg and Lang, Florian
Cellular Physiology and Biochemistry, ISSN 1015-8987, 08/2015, Volume 36, Issue 6, pp. 2287 - 2298
SOCE | CXCL12 | CRAC channel | Intracellular Ca 2+ release | ATP
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8. Full Text Ankyrin-B reduction enhances Ca spark-mediated SR Ca release promoting cardiac myocyte arrhythmic activity
by Camors, Emmanuel and Mohler, Peter J and Bers, Donald M and Despa, Sanda
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2012, Volume 52, Issue 6, pp. 1240 - 1248
Abstract Ankyrin-B (AnkB) loss-of-function may cause ventricular arrhythmias and sudden cardiac death in humans. Cardiac myocytes from AnkB heterozygous mice... 
Cardiovascular | SR Ca leak | Intracellular Na | Na/K-ATPase | Na/Ca exchanger | Ankyrin-B | Ca sparks | LEAK | CARDIAC & CARDIOVASCULAR SYSTEMS | ALPHA-SUBUNIT | HEART-FAILURE | CARDIOMYOCYTES | MOUSE VENTRICULAR MYOCYTES | CELL BIOLOGY | RYANODINE RECEPTOR | TRANSIENTS | SODIUM-CALCIUM EXCHANGE | DYSFUNCTION | Arrhythmias, Cardiac - metabolism | Calcium - metabolism | Ryanodine Receptor Calcium Release Channel - metabolism | Diastole - physiology | Mice, Knockout | Sodium-Potassium-Exchanging ATPase - metabolism | Animals | Sodium-Calcium Exchanger - metabolism | Ankyrins - genetics | Ankyrins - metabolism | Myocytes, Cardiac - metabolism | Mice | Sarcoplasmic Reticulum - metabolism | Calcium Signaling | Index Medicus | intracellular Na | Ca exchanger | Na | K-ATPase | ankyrin-B
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9. Full Text Effects of Amyloid-β peptides on voltage-gated L-Type Ca v1.2 and Ca v1.3 Ca 2+ channels
by Kim, Sunoh and Rhim, Hyewhon
Molecules and Cells, ISSN 1016-8478, 09/2011, Volume 32, Issue 3, pp. 289 - 294
Co-immunoprecipitation | channels | GST pulldown | Intracellular Ca | L-type Ca | Alzheimer's disease
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10. Full Text Increased intracellular Ca^sup 2+^ concentrations prevent membrane localization of PH domains through the formation of Ca^sup 2+^-phosphoinositides
by Jin Ku Kang and Ok-Hee Kim and June Hur and So Hee Yu and Santosh Lamichhane and Jin Wook Lee and Uttam Ojha and Jeong Hee Hong and Cheol Soon Lee and Ji-Young Cha and Young Jae Lee and Seung-Soon Im and Young Joo Park and Cheol Soo Choi and Dae Ho Lee and In-Kyu Lee and Byung-Chul Oh
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2017, Volume 114, Issue 45, p. 11926
Insulin resistance, a key etiological factor in metabolic syndrome, is closely linked to ectopic lipid accumulation and increased intracellular Ca2+... 
Phosphates | Membranes | Phosphorylation | Calcium | Liver | Homeostasis | Homology | Intracellular signalling | AKT protein | Kinases | Inactivation | Proteins | Calcium signalling | Etiology | Pleckstrin | Localization | Calcium homeostasis | Binding | Phosphoinositides | Calcium (intracellular) | Deactivation | Phosphatidylinositol 3,4,5-triphosphate | Hyperlipidemia | Muscles | Substrate inhibition | Pharmacology | Insulin | Resistance factors | Cells | Phospholipase C | Phospholipase | Insulin receptor substrate 1 | Hepatocytes | Insulin resistance | Pips | Intracellular | Position (location) | Metabolic disorders
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11. Full Text Presenilin 2 modulates endoplasmic reticulum (ER)-mitochondria interactions and Ca 2+ cross-talk
by Zampese, Enrico and Fasolato, Cristina and Kipanyula, Maulilio J and Bortolozzi, Mario and Pozzan, Tullio and Pizzo, Paola
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 02/2011, Volume 108, Issue 7, pp. 2777 - 2782
Fluorescent Ca | Fluorescence resonance energy transfer | Intracellular organelle tethering | probe
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12. Full Text Insemination or phosphatidic acid induces an outwardly spiraling disk of elevated Ca 2+ to produce the Ca 2+ wave during Xenopus laevis fertilization
by Fees, Colby P and Stith, Bradley J
Developmental Biology, ISSN 0012-1606, 04/2019, Volume 448, Issue 1, pp. 59 - 68
During Xenopus fertilization, the initial intracellular calcium ((Ca ) ) release at the sperm-egg binding site (hot spot) has not been described without the... 
Inositol 1, 4, 5-trisphosphate | Intracellular calcium wave | Fertilization | Endoplasmic reticulum | Phospholipase D | Phosphatidic acid
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13. Full Text Differential targeting and signalling of voltage-gated T-type Ca(v)3.2 and L-type Ca(v)1.2 channels to ryanodine receptors in mesenteric arteries
by Fan, G and Kassmann, M and Hashad, AM and Welsh, DG and Gollasch, M
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 10/2018, Volume 596, Issue 20, pp. 4863 - 4877
Recent data suggest that T-type Ca(v)3.2 channels in arterial vascular smooth muscle cells (VSMCs) and pits structure of caveolae could contribute to... 
SMOOTH-MUSCLE | PHYSIOLOGY | CALCIUM-CHANNELS | RAT | BETA-1 SUBUNIT | GENETIC ABLATION | CA2+ CHANNELS | CEREBRAL-ARTERIES | NEGATIVE-FEEDBACK | NEUROSCIENCES | K+ CHANNELS | SPARKS
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14. Full Text The investigation of the pyrethroid insecticide lambda-cyhalothrin (LCT)-affected Ca^sup 2+^ homeostasis and -activated Ca^sup 2+^-associated mitochondrial apoptotic pathway in normal human astrocytes: The evaluation of protective effects of BAPTA-AM (a selective Ca^sup 2+^ chelator)
by Shu-Shong Hsu and Chung-Ren Jan and Wei-Zhe Liang
Neurotoxicology, ISSN 0161-813X, 12/2018, Volume 69, p. 97
Exposure to insecticides has been found to have deleterious effects on human health. Lambda-cyhalothrin (LCT), a mixture of isomers of cyhalothrin, is a... 
Brain | Animal models | Bax protein | Bcl-2 protein | Toxicity | Homeostasis | Insecticides | Cytotoxicity | Isomers | Neuromodulation | Econazole | Modulators | Calcium influx | Ca2+-transporting ATPase | Calcium signalling | Proteins | Neurotoxicity | Mitochondria | Inhibition | Pretreatment | Calcium homeostasis | Cyhalothrin | Calcium channels | Calcium (intracellular) | Incubation | Neurons | Astrocytes | Pest control | Caspase | Control programs | Ethane | Caspase-9 | Endoplasmic reticulum | Calcium (extracellular) | Calcium (reticular) | Calcium ions | Apoptosis
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15. Full Text The prokaryotic Na+/Ca^sup 2+^ exchanger NCX_Mj transports Na+ and Ca^sup 2+^ in a 3:1 stoichiometry
by Irina Shlosman and Fabrizio Marinelli and José D Faraldo-Gómez and Joseph A Mindell
The Journal of General Physiology, ISSN 0022-1295, 01/2018, Volume 150, Issue 1, p. 51
Intracellular Ca2+ signals control a wide array of cellular processes. These signals require spatial and temporal regulation of the intracellular 2+... 
Stoichiometry | Membranes | Calcium (intracellular) | Spatial discrimination | Biophysics | Antiport | Cells | Membrane proteins | Calcium signalling | Na+/Ca2+-exchanging ATPase | Sodium | Physiology | Calcium transport | Liposomes | Intracellular | Structure-function relationships
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16. Full Text Cell-Permeable Esterase-Activated Ca(II)-Sensitive MRI Contrast Agent
by MacRenaris, Keith W and Ma, Zhidong and Krueger, Ruby L and Carney, Christiane E and Meade, Thomas J
Bioconjugate Chemistry, ISSN 1043-1802, 02/2016, Volume 27, Issue 2, pp. 465 - 473
Calcium [Ca(II)] is a fundamental transducer of electrical activity in the central nervous system (CNS). Influx of Ca(II) into the cytosol is responsible for... 
BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOCHEMICAL RESEARCH METHODS | CHEMISTRY, ORGANIC | EXTRACELLULAR CALCIUM FLUCTUATIONS | HYPOXIA | OSCILLATION | CHEMISTRY, MULTIDISCIPLINARY | CA2 | PRODRUGS | IN-VIVO | NEURONS | PROBE | EXPRESSION | FMRI | Cell Line | Calcium - metabolism | Cell Membrane Permeability | Contrast Media - pharmacokinetics | Esterases - metabolism | Magnetic Resonance Imaging - methods | Calcium - analysis | Hippocampus - cytology | Hippocampus - metabolism | Extracellular Space - metabolism | Intracellular Space - chemistry | Animals | Intracellular Space - metabolism | Contrast Media - metabolism | Extracellular Space - chemistry | Contrast Media - chemistry | Mice | Index Medicus
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17. Full Text Comparative genome analysis of "Candidatus Phytoplasma australiense" (subgroup tuf-Australia I; rp-A) and "Ca. phytoplasma asteris" strains OY-M and AY-WB
by Tran-Nguyen, L.T.T and Kube, M and Schneider, B and Reinhardt, R and Gibb, K.S
Journal of Bacteriology, ISSN 0021-9193, 06/2008, Volume 190, Issue 11, pp. 3979 - 3991
The chromosome sequence of "Candidatus Phytoplasma australiense" (subgroup tuf-Australia I; rp-A), associated with dieback in papaya, Australian grapevine... 
GLOBAL TRANSCRIPTIONAL CONTROL | LEGIONELLA-PNEUMOPHILA | NEW-ZEALAND | BACILLUS-SUBTILIS | ESCHERICHIA-COLI | MICROBIOLOGY | EXTRACHROMOSOMAL DNAS | IMMUNODOMINANT MEMBRANE-PROTEIN | INTRACELLULAR MULTIPLICATION | NUCLEOTIDE-SEQUENCE | ONION YELLOWS PHYTOPLASMA | Amino Acid Sequence | Genes, Bacterial | Genome, Bacterial | Chromosomes, Bacterial - genetics | Phytoplasma - classification | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Molecular Sequence Data | Bacterial Proteins - metabolism | Phytoplasma - metabolism | Gene Expression Regulation, Bacterial - physiology | Phytoplasma - genetics | Physiological aspects | Research | Bacterial genetics | Plasmids | Genomics | Proteins | Bacteria | Chromosomes | Deoxyribonucleic acid--DNA | Bacteriology | Index Medicus
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18. Full Text CaMKII delta(C) Slows [Ca](i) Decline in Cardiac Myocytes by Promoting Ca Sparks
by Guo, T and Zhang, T and Ginsburg, KS and Mishra, S and Brown, JH and Bers, DM
BIOPHYSICAL JOURNAL, ISSN 0006-3495, 06/2012, Volume 102, Issue 11, pp. 2461 - 2470
Acute activation of calcium/calmodulin-dependent protein kinase (CaMKII) in permeabilized phospholamban knockout (PLN-KO) mouse myocytes phosphorylates... 
PRESSURE-OVERLOAD | BIOPHYSICS | RYANODINE RECEPTOR | INTRACELLULAR CALCIUM | HEART-FAILURE | FERRET VENTRICULAR MYOCYTES | SARCOPLASMIC-RETICULUM | CALMODULIN KINASE | UP-REGULATION | PROTEIN-KINASE-II | RABBIT HEART
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19. Full Text Ambiguous interactions between diastolic and SR Ca^sup 2+^ in the regulation of cardiac Ca^sup 2+^ release
by Eric A Sobie and George SB  Williams and WJ Lederer
The Journal of General Physiology, ISSN 0022-1295, 09/2017, Volume 149, Issue 9, p. 847
In all types of muscle cells, contraction is initiated by an increase in intracellular Ca2+. Another similarity among skeletal, cardiac, and smooth muscle... 
Heart | Calcium (intracellular) | Calcium | Cardiac muscle | Cardiomyocytes | Smooth muscle | Physiology | Coexistence | Muscle contraction | Heart diseases | Contraction | Skeletal muscle
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20. Full Text MicroRNA-150 modulates intracellular Ca 2+ levels in naïve CD8+ T cells by targeting TMEM20
by Kim, Tae-Don and Jung, Hong-Ryul and Seo, Sang-Hwan and Oh, Se-Chan and Ban, Youngho and Tan, Xiaoxia and Min Kim, Jung and Hyun Lee, Sang and Koh, Duk-Su and Jung, Haiyoung and Park, Young-Jun and Ran Yoon, Suk and Doh, Junsang and Ha, Sang-Jun and Choi, Inpyo and Greenberg, Philip D
Scientific Reports, ISSN 2045-2322, 12/2017, Volume 7, Issue 1, pp. 2623 - 13
Regulation of intracellular Ca signaling is a major determinant of CD8 T cell responsiveness, but the mechanisms underlying this regulation of Ca levels,... 
Cell Line | Cell Proliferation | Lymphocyte Activation | Mice, Inbred C57BL | NFATC Transcription Factors - metabolism | Gene Expression Regulation | Clonal Anergy | MicroRNAs - metabolism | Mice, Knockout | Plasma Membrane Calcium-Transporting ATPases - metabolism | Animals | CD8-Positive T-Lymphocytes - metabolism | MicroRNAs - genetics | Calcium Signaling | Cell proliferation | Calcium (intracellular) | Anergy | CD8 antigen | MiRNA | Intracellular signalling | Lymphocytes T | Calcium signalling | Cell activation | NF-AT1 protein | Lymphocytes | MicroRNAs | Reinstatement | Cbl-b protein | Antitumor activity | Egr-2 protein | Intracellular | Index Medicus
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