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Journal Article
Molecular Cell, ISSN 1097-2765, 2009, Volume 35, Issue 5, pp. 563 - 573
The target of rapamycin complex 1 (TORC1) is a central regulator of eukaryotic cell growth that is activated by a variety of hormones (e.g., insulin) and... 
CELLBIO | PROTEINS | SIGNALING | YEAST SACCHAROMYCES-CEREVISIAE | CELL-GROWTH CONTROL | SIGNALING PATHWAYS | FUNCTIONAL HOMOLOG | RAG GTPASES | VACUOLE FUSION | BIOCHEMISTRY & MOLECULAR BIOLOGY | AMINO-ACID PERMEASE | COMPONENT | GTP-BINDING PROTEINS | GAP1 PERMEASE | CELL BIOLOGY | Vacuoles - enzymology | Intracellular Membranes - enzymology | Saccharomyces cerevisiae - genetics | Multiprotein Complexes | Adaptor Proteins, Vesicular Transport - genetics | Saccharomyces cerevisiae - drug effects | Guanosine Triphosphate - metabolism | Adaptor Proteins, Vesicular Transport - metabolism | Vacuoles - drug effects | DNA-Binding Proteins - metabolism | Amino Acids - metabolism | Time Factors | Guanine Nucleotide Exchange Factors - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Guanosine Diphosphate - metabolism | Protein Synthesis Inhibitors - pharmacology | Protein-Serine-Threonine Kinases - metabolism | Guanine Nucleotide Exchange Factors - genetics | Signal Transduction | Saccharomyces cerevisiae Proteins - antagonists & inhibitors | Monomeric GTP-Binding Proteins - genetics | Saccharomyces cerevisiae Proteins - genetics | Amino Acid Transport Systems - metabolism | Sirolimus - pharmacology | Cycloheximide - pharmacology | Protein Transport | Transcription Factors - metabolism | Monomeric GTP-Binding Proteins - metabolism | Saccharomyces cerevisiae Proteins - metabolism | Protein Binding | Saccharomyces cerevisiae - enzymology | Endosomes - enzymology | Intracellular Membranes - drug effects | Mutation | Saccharomyces cerevisiae - growth & development | Proteins | Purines | Amino acids | Gross domestic product | Guanosine
Journal Article
Neuron, ISSN 0896-6273, 2004, Volume 43, Issue 1, pp. 5 - 17
One cause of amyotrophic lateral sclerosis (ALS) is mutation in ubiquitously expressed copper/zinc superoxide dismutase (SOD1), but the mechanism of toxicity... 
COPPER CHAPERONE | DEAFNESS DYSTONIA SYNDROME | PROPOSED MECHANISM | CU,ZN-SUPEROXIDE DISMUTASE | MOTONEURON DEGENERATION | CU/ZN SUPEROXIDE-DISMUTASE | AMYOTROPHIC-LATERAL-SCLEROSIS | MOTOR-NEURON DISEASE | TRANSGENIC MOUSE MODEL | NEUROSCIENCES | MOLECULAR-WEIGHT COMPLEXES | Mitochondria - enzymology | Protein Binding - genetics | Superoxide Dismutase - genetics | Intracellular Membranes - enzymology | Molecular Chaperones - metabolism | Humans | Nerve Degeneration - physiopathology | Nerve Degeneration - genetics | Cytoplasm - metabolism | Intracellular Membranes - ultrastructure | Superoxide Dismutase - toxicity | Spinal Cord - chemistry | Protein Isoforms - metabolism | Mitochondria - genetics | Motor Neuron Disease - genetics | Mitochondrial Proteins - metabolism | Spinal Cord - pathology | Motor Neuron Disease - enzymology | Intracellular Membranes - pathology | Superoxide Dismutase - metabolism | Disease Models, Animal | Nerve Degeneration - enzymology | Spinal Cord - enzymology | Mice, Transgenic | Mitochondria - pathology | Microscopy, Electron | Mutation - genetics | Protein Folding | Protein Transport - genetics | Macromolecular Substances | Motor Neuron Disease - pathology | Animals | Mice | Superoxide Dismutase-1 | Aging - metabolism | Protein Isoforms - genetics | Medical research | Amyotrophic lateral sclerosis | Spinal cord | Mutation | Toxicity | Rodents | Protein Binding/genetics | Aging/metabolism | Mice; Transgenic | Protein Isoforms/genetics/metabolism | Mutation/genetics | Cytoplasm/metabolism | Nerve Degeneration/enzymology/genetics/physiopathology | Microscopy; Electron | Mitochondrial Proteins/metabolism | Spinal Cord/chemistry/enzymology/pathology | Mitochondria/enzymology/genetics/pathology | Motor Neuron Disease/enzymology/genetics/pathology | Protein Transport/genetics | Intracellular Membranes/enzymology/pathology/ultrastructure | Molecular Chaperones/metabolism | Disease Models; Animal | Superoxide Dismutase/genetics/metabolism/toxicity
Journal Article
Molecular Cell, ISSN 1097-2765, 09/2017, Volume 67, Issue 6, pp. 974 - 989.e6
Journal Article
Journal Article
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2017, Volume 19, Issue 7, pp. 787 - 798
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 3/2009, Volume 106, Issue 12, pp. 4635 - 4640
Journal Article
1987, Research monographs in cell and tissue physiology, ISBN 0444808892, Volume 14, xvii, 359
Book
Journal of Biological Chemistry, ISSN 0021-9258, 10/2004, Volume 279, Issue 43, pp. 44945 - 44954
Journal Article
Nature, ISSN 0028-0836, 08/2014, Volume 512, Issue 7515, pp. 441 - 444
Journal Article