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PLoS ONE, ISSN 1932-6203, 02/2014, Volume 9, Issue 2, pp. e88193 - e88193
Intrinsic resistance to cytotoxic drugs has been a main issue in cancer therapy for decades. Microenvironmental acidity is a simple while highly efficient... 
APOPTOSIS | PLASMA | VESICLES | MULTIDISCIPLINARY SCIENCES | INTRACELLULAR PH | TRAFFICKING | PROTON PUMP INHIBITORS | MECHANISMS | EXPRESSION | H+-ATPASES | CHEMOTHERAPY | Exosomes - drug effects | Exosomes - metabolism | Proton Pump Inhibitors - pharmacology | Intracellular Space - drug effects | Humans | Extracellular Space - drug effects | Chromatography, High Pressure Liquid | Cisplatin - pharmacology | Melanoma - pathology | Mice, SCID | Spectrophotometry, Atomic | Xenograft Model Antitumor Assays | Extracellular Space - metabolism | Reference Standards | Animals | Solutions | Hydrogen-Ion Concentration - drug effects | Intracellular Space - metabolism | Cell Line, Tumor | Female | Cell Death - drug effects | Buffers | Cellular Microenvironment - drug effects | Drug Resistance, Neoplasm - drug effects | Drugs | Drug delivery systems | Care and treatment | Melanoma | Health aspects | Cisplatin | Vehicles | Cancer | Cell culture | Toxicity | Chemoresistance | Cytotoxicity | Drug delivery | Metastasis | Drug resistance | Exosomes | pH effects | Cancer therapies | Skin cancer | Prevention | Hydrogen ions | Xenografts | Biocompatibility | Inhibition | Pretreatment | Deoxyribonucleic acid--DNA | Antigens | Cultures | Acidity | Breast cancer | Liquid chromatography | High-performance liquid chromatography | Medicine | Studies | Inductively coupled plasma | Protonation | Scientific imaging | Acidosis | Mass spectrometry | Tumors | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
Nature, ISSN 0028-0836, 11/2015, Volume 527, Issue 7578, pp. 323 - 328
Journal Article
Cell Stem Cell, ISSN 1934-5909, 04/2013, Volume 12, Issue 4, pp. 487 - 496
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 72, pp. 74 - 89
Abstract Dual responsive nanoparticles are developed for co-delivery of multiple anticancer drugs to target the drug resistance mechanisms of cancer stem-like... 
Advanced Basic Science | Dentistry | Topoisomerase | Co-delivery | Drug resistance | Cancer stem-like cell | CD44 | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | TRANSCRIPTION | TOPOISOMERASE-I | DRUG-RESISTANCE | COMBINATION | PACLITAXEL | THERAPY | ANTICANCER | DNA TOPOISOMERASES | ANTITUMOR EFFICACY | XENOGRAFTS | Nanoparticles - chemistry | Neoplastic Stem Cells - drug effects | Humans | Male | Spheroids, Cellular - cytology | Drug Delivery Systems | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Spheroids, Cellular - drug effects | Camptothecin - analogs & derivatives | Poloxamer - chemistry | Tissue Distribution - drug effects | Intracellular Space - drug effects | Lactic Acid - chemistry | Endocytosis - drug effects | Hyaluronic Acid - chemistry | Nanoparticles - ultrastructure | Animals | Chitosan - chemistry | Mice, Nude | Intracellular Space - metabolism | Polyglycolic Acid - chemistry | Cell Line, Tumor | Drug Liberation | Camptothecin - pharmacology | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | Hydrogen-Ion Concentration | Nanoparticles | Anthracyclines | Hyaluronic acid | Doxorubicin | Drug approval | Cancer | Biomedical engineering | Index Medicus | Drugs | Surgical implants | Biomedical materials | Pluronic F127 | Hydroxyapatite | Chitosan | co-delivery | cancer stem-like cell | topoisomerase | drug resistance
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 32, Issue 32, pp. 8281 - 8290
Journal Article
Journal of Experimental Botany, ISSN 0022-0957, 1/2012, Volume 63, Issue 8, pp. 3207 - 3218
Changes in pH are now widely accepted as a signalling mechanism in cells. In plants, proton pumps in the plasma membrane and tonoplast play a key role in... 
Mesophyll cells | Adhesives | Perfusion | Imaging | Plant roots | Sensors | Plants | Calibration | Cytosol | RESEARCH PAPER | GFP | Auxin | PHusion | Arabidopsis | ATPase | pH homeostasis | Apoplast | Cytoplasm | Sensor | auxin | INTRACELLULAR PH | ROOT-TIPS | pHusion | STOMATAL CLOSURE | PLANT SCIENCES | cytoplasm | GREEN FLUORESCENT PROTEIN | CYTOSOLIC CA2 | ALGAE | H+ BUFFERS | H+-ATPase | sensor | ABSCISIC-ACID | LIVING CELLS | Organ Specificity - drug effects | Gene Expression - drug effects | Cytosol - drug effects | Extracellular Space - drug effects | Imaging, Three-Dimensional - methods | Plant Roots - drug effects | Extracellular Space - metabolism | Hydrogen-Ion Concentration - drug effects | Cell Membrane - metabolism | Mesophyll Cells - drug effects | Mesophyll Cells - metabolism | Homeostasis - drug effects | Cell Membrane - drug effects | Mesophyll Cells - cytology | Alkalies | Cell Survival - drug effects | Arabidopsis - drug effects | Intracellular Space - drug effects | Plant Roots - metabolism | Seedlings - cytology | Arabidopsis - cytology | Adhesives - pharmacology | Genes, Reporter - genetics | Plant Roots - cytology | Seedlings - drug effects | Arabidopsis - metabolism | Indoleacetic Acids - pharmacology | Intracellular Space - metabolism | Biosensing Techniques - methods | Cytosol - metabolism | Index Medicus | Research Papers
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 5, pp. 1477 - 1488
Journal Article
Biomaterials, ISSN 0142-9612, 2011, Volume 33, Issue 9, pp. 2780 - 2790
Abstract Co-delivery of siRNA and chemotherapeutic agents has been developed to combat multidrug resistance in cancer therapy. Recently, we developed a series... 
Advanced Basic Science | Dentistry | QDs | β-CD | Co-delivery | siRNA | Doxorubicin | Multidrug resistance | SiRNA | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | MODULATORS | MECHANISMS | DRUG-RESISTANCE | CANCER | P-GLYCOPROTEIN | NANOPARTICLES | MDR1 | THERAPY | beta-CD | INHIBITORS | EXPRESSION | RNA, Small Interfering - genetics | Drug Resistance, Multiple - drug effects | Humans | ATP-Binding Cassette, Sub-Family B, Member 1 - metabolism | Adsorption - drug effects | Cell Tracking - methods | Flow Cytometry | Time Factors | Gene Expression Regulation, Neoplastic - drug effects | Gene Transfer Techniques | Microscopy, Electron, Transmission | Drug Resistance, Multiple - genetics | Intracellular Space - drug effects | Spectrometry, Fluorescence | Static Electricity | Cell Shape - drug effects | Particle Size | Microscopy, Confocal | Drug Resistance, Neoplasm - genetics | Quantum Dots | ATP-Binding Cassette, Sub-Family B, Member 1 - genetics | Intracellular Space - metabolism | ATP Binding Cassette Transporter, Sub-Family B | HeLa Cells | Drug Delivery Systems - methods | Doxorubicin - pharmacology | Drug Resistance, Neoplasm - drug effects | RNA, Small Interfering - metabolism | Drug resistance in microorganisms | Chemotherapy | Anthracyclines | Biological products | Messenger RNA | Genes | Fluorescence | Cyclodextrins | Cancer | Index Medicus
Journal Article
Biomaterials, ISSN 0142-9612, 2009, Volume 31, Issue 10, pp. 2882 - 2892
Journal Article