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1. Full Text Copper(II)–Graphitic Carbon Nitride Triggered Synergy: Improved ROS Generation and Reduced Glutathione Levels for Enhanced Photodynamic Therapy
by Ju, Enguo and Dong, Kai and Chen, Zhaowei and Liu, Zhen and Liu, Chaoqun and Huang, Yanyan and Wang, Zhenzhen and Pu, Fang and Ren, Jinsong and Qu, Xiaogang
Angewandte Chemie (International ed.), ISSN 1433-7851, 09/2016, Volume 55, Issue 38, pp. 11467 - 11471
synergetic effects | glutathione | photodynamic therapy | graphitic carbon nitride | reactive oxygen species | Physical Sciences | Chemistry | Chemistry, Multidisciplinary | Science & Technology | Hydrogen peroxide | Thiols | Boron nitride | Copper compounds | Superoxide | Photochemotherapy | Cancer | Efficiency | Oxidation | Photodynamic therapy | Oxygen | Integration | Light irradiation | Radiation | Light emitting diodes | Nanostructure | Carbon | Light effects | Carbon nitride | Reduction | Depletion | Hydroxyl radicals | Irradiation | Intracellular | Copper | Light levels | Glutathione | Index Medicus
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2. Full Text Cancer with low cathepsin D levels is susceptible to vacuolar (H+)‐ATPase inhibition
by Kitazawa, Satoshi and Nishizawa, Satoru and Nakagawa, Hideyuki and Funata, Masaaki and Nishimura, Kazuho and Soga, Tomoyoshi and Hara, Takahito
Cancer science, ISSN 1347-9032, 06/2017, Volume 108, Issue 6, pp. 1185 - 1193
V‐ATPase | Cathepsin D | patient selection marker | colorectal cancer | vulnerability | V-ATPase | Life Sciences & Biomedicine | Oncology | Science & Technology | RNA, Small Interfering - genetics | Vacuolar Proton-Translocating ATPases - genetics | Endoplasmic Reticulum Stress - drug effects | HCT116 Cells | Humans | Up-Regulation - genetics | Signal Transduction - genetics | Down-Regulation - drug effects | Endoplasmic Reticulum Stress - genetics | Autophagy - drug effects | Down-Regulation - genetics | Neoplasms - drug therapy | Up-Regulation - drug effects | Vacuolar Proton-Translocating ATPases - antagonists & inhibitors | TOR Serine-Threonine Kinases - genetics | Neoplasms - genetics | Signal Transduction - drug effects | Cathepsin D - genetics | Cell Line, Tumor | Antineoplastic Agents - pharmacology | Autophagy - genetics | Oncology, Experimental | Colorectal cancer | Cathepsins | Amino acids | Research | Health aspects | Adenosine triphosphatase | Cancer | TOR protein | Visualization | Peptides | Laboratories | Toxicity | Colorectal carcinoma | Amino acid starvation | Drug development | Kinases | Autophagy | D gene | Proteins | Cell growth | Antitumor agents | Nutrients | Pharmaceutical industry | Starvation | Capillary electrophoresis | Research & development--R&D | Therapeutic applications | Rapamycin | siRNA | Patients | Collagen | Scientific imaging | Intracellular | Endoplasmic reticulum | Mass spectrometry | Phagocytosis | Tumors | Index Medicus | Original
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3. Full Text Molecular identification of a renal urate-anion exchanger that regulates blood urate levels
by Kanai, Yoshikatsu and Hosoya, Tatsuo and Enomoto, Atsushi and Sekine, Takashi and Shigeta, Yasuhiro and Ho Cha, Seok and Niwa, Toshimitsu and Hosoyamada, Makoto and Kikuchi, Yuichi and Kimura, Hiroaki and Jutabha, Promsuk and Matsuo, Hirotaka and Shimokata, Kaoru and Ichida, Kimiyoshi and Takeda, Michio and Endou, Hitoshi and Chairoungdua, Arthit and Igarashi, Takashi and Oda, Takashi
Nature (London), ISSN 0028-0836, 05/2002, Volume 417, Issue 6887, pp. 447 - 452
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Fundamental and applied biological sciences. Psychology | Biological and medical sciences | Cell physiology | Molecular and cellular biology | Membrane and intracellular transports | Immunohistochemistry | Xenopus | Humans | Kidney Tubules, Proximal - chemistry | Molecular Sequence Data | Substrate Specificity | RNA, Messenger - metabolism | Kidney - metabolism | Biological Transport | Cloning, Molecular | Carrier Proteins - chemistry | Uric Acid - blood | Anions - blood | Amino Acid Sequence | Uric Acid - metabolism | Oocytes - metabolism | RNA, Messenger - genetics | Organic Cation Transport Proteins | Anions - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Organic Anion Transporters | Kidney Tubules, Proximal - metabolism | Kidney - chemistry | Mutation | Kidneys | Acids | Molecular biology | Blood | SLC22A12 gene | URAT1 protein | Index Medicus
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4. Full Text Elevated Tribbles homolog 2-specific antibody levels in narcolepsy patients
by Cvetkovic-Lopes, Vesna and Bayer, Laurence and Dorsaz, Stéphane and Maret, Stéphanie and Pradervand, Sylvain and Dauvilliers, Yves and Lecendreux, Michel and Lammers, Gert-Jan and Donjacour, Claire E. H. M and Du Pasquier, Renaud A and Pfister, Corinne and Petit, Brice and Hor, Hyun and Mühlethaler, Michel and Tafti, Mehdi
The Journal of clinical investigation, ISSN 0021-9738, 03/2010, Volume 120, Issue 3, pp. 713 - 719
Life Sciences & Biomedicine | Medicine, Research & Experimental | Science & Technology | Research & Experimental Medicine | Neurons - pathology | Narcolepsy - blood | Autoantigens - metabolism | Autoantibodies - blood | Humans | Sleep Initiation and Maintenance Disorders - pathology | Intracellular Signaling Peptides and Proteins - immunology | Male | Intracellular Signaling Peptides and Proteins - metabolism | Autoantigens - genetics | Autoimmune Diseases - genetics | Time Factors | Female | Neurons - metabolism | Neuropeptides - genetics | Autoimmune Diseases - pathology | Intracellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Narcolepsy - pathology | Hypothalamus - immunology | Severity of Illness Index | Orexins | Autoimmune Diseases - immunology | Neurons - immunology | Protein-Serine-Threonine Kinases - genetics | Mice, Transgenic | Neuropeptides - metabolism | Hypothalamus - pathology | Calcium-Calmodulin-Dependent Protein Kinases | Sleep Initiation and Maintenance Disorders - blood | Autoimmune Diseases - blood | Narcolepsy - immunology | Narcolepsy - genetics | Autoantibodies - immunology | Animals | Hypothalamus - metabolism | Sleep Initiation and Maintenance Disorders - immunology | Autoantigens - immunology | Sleep Initiation and Maintenance Disorders - genetics | Protein-Serine-Threonine Kinases - immunology | Mice | Neuropeptides - immunology | Usage | Care and treatment | Narcolepsy | Genetic aspects | Research | Gene expression | Enzyme-linked immunosorbent assay | Apoptosis | Index Medicus | Abridged Index Medicus
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5. Full Text Arabidopsis thaliana High-Affinity Phosphate Transporters Exhibit Multiple Levels of Posttranslational Regulation
by Vincent Bayle and Jean-François Arrighi and Audrey Creff and Claude Nespoulous and Jérôme Vialaret and Michel Rossignol and Esperanza Gonzalez and Javier Paz-Ares and Laurent Nussaume
The Plant cell, ISSN 1040-4651, 4/2011, Volume 23, Issue 4, pp. 1523 - 1535
Phosphates | Proteins | Phosphorylation | Phosphate transport proteins | Fluorescence | Cell membranes | Plants | Physiological regulation | Endosomes | Plant cells | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Plant Sciences | Science & Technology | Cell Biology | Amino Acid Sequence | Green Fluorescent Proteins - metabolism | Protein Biosynthesis | Phosphate Transport Proteins - metabolism | COP-Coated Vesicles - metabolism | Endoplasmic Reticulum - metabolism | Molecular Sequence Data | Organ Specificity | Recombinant Fusion Proteins - metabolism | Endosomes - metabolism | Phosphate Transport Proteins - chemistry | Arabidopsis - metabolism | Protein Transport | Arabidopsis - genetics | Arabidopsis Proteins - metabolism | Cell Compartmentation | Phosphates - metabolism | Arabidopsis Proteins - chemistry | Intracellular Space - metabolism | Gene Expression Regulation, Plant | Phosphates - deficiency | Cell Membrane - metabolism | Protein Stability | Post-translational modification | Arabidopsis thaliana | Plant physiology | Plant genetics | Physiological aspects | Genetic aspects | Research | Index Medicus | Life Sciences
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6. Full Text The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1
by Tsun, Zhi-Yang and Bar-Peled, Liron and Chantranupong, Lynne and Zoncu, Roberto and Wang, Tim and Kim, Choah and Spooner, Eric and Sabatini, DavidM
Molecular cell, ISSN 1097-2765, 11/2013, Volume 52, Issue 4, pp. 495 - 505
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Signal Transduction | TOR Serine-Threonine Kinases - metabolism | Humans | Mechanistic Target of Rapamycin Complex 1 | Protein Transport | Amino Acids - metabolism | Multiprotein Complexes - metabolism | Tumor Suppressor Proteins - physiology | Carrier Proteins - metabolism | Lysosomes - metabolism | Monomeric GTP-Binding Proteins - metabolism | HEK293 Cells | Proto-Oncogene Proteins - physiology | Protein Binding | GTPase-Activating Proteins - physiology | Intracellular Membranes - metabolism | Amino acids | G proteins | Gross domestic product | Tumors | Integrins | Index Medicus
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7. Full Text Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction
by Blouin, Ashley M and Fried, Itzhak and Wilson, Charles L and Staba, Richard J and Behnke, Eric J and Lam, Hoa A and Maidment, Nigel T and Karlsson, Karl Æ and Lapierre, Jennifer L and Siegel, Jerome M
Nature communications, ISSN 2041-1723, 2013, Volume 4, Issue 1, pp. 1547 - 1547
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Emotions - physiology | Orexins | Humans | Middle Aged | Amygdala - metabolism | Rats | Male | Neuropeptides - metabolism | Electrodes, Implanted | Intracellular Signaling Peptides and Proteins - metabolism | Melanins - metabolism | Young Adult | Animals | Hypothalamus - metabolism | Microdialysis | Time Factors | Hypothalamic Hormones - metabolism | Pituitary Hormones - metabolism | Wakefulness - physiology | Adult | Female | Behavior | Sleep - physiology | Interpersonal Relations | Index Medicus
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8. Full Text Single Cell “Glucose Nanosensor” Verifies Elevated Glucose Levels in Individual Cancer Cells
by Nascimento, Raphael A. S and Özel, Rıfat Emrah and Mak, Wai Han and Mulato, Marcelo and Singaram, Bakthan and Pourmand, Nader
Nano letters, ISSN 1530-6984, 02/2016, Volume 16, Issue 2, pp. 1194 - 1200
nanopipette | single cell | cancer metabolomics | biosensor | nanopore | intracellular glucose | Materials Science | Materials Science, Multidisciplinary | Physics, Condensed Matter | Science & Technology - Other Topics | Chemistry, Physical | Physics | Science & Technology | Physics, Applied | Physical Sciences | Chemistry | Nanoscience & Nanotechnology | Technology | Chemistry, Multidisciplinary | Glucose Oxidase - chemistry | Enzymes, Immobilized - chemistry | Cell Proliferation | Humans | Oxidative Phosphorylation | Breast Neoplasms - metabolism | Neoplasm Metastasis | MCF-7 Cells | Breast Neoplasms - pathology | Biosensing Techniques | Glucose - metabolism | Female | Gluconates - chemistry | Single-Cell Analysis | Glucose - isolation & purification | Index Medicus | Progressions | Nanostructure | Glucose | Biosensors | Impedance | Signatures | Sampling | Cancer
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9. Full Text Epithelial–mesenchymal transition is regulated at post‐transcriptional levels by transforming growth factor‐β signaling during tumor progression
by Saitoh, Masao
Cancer science, ISSN 1347-9032, 05/2015, Volume 106, Issue 5, pp. 481 - 488
TGF‐β | Smad | Cancer biology | signal transduction | EMT | Signal transduction | TGF-β | Neoplasms - metabolism | Signal Transduction | Epithelial-Mesenchymal Transition - physiology | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | MicroRNAs - metabolism | Transcription Factors - genetics | Transcription Factors - metabolism | Animals | MicroRNAs - genetics | Protein Processing, Post-Translational | Neoplasms - pathology | Transforming Growth Factor beta - metabolism | Transcription factors | Phosphorylation | Motility | Transcription | Mesenchyme | Epithelial cells | Gene regulation | Genes | Intracellular signalling | Kinases | Proteins | Embryogenesis | Cooperation | Fibroblasts | Polarity | Physiology | Tumorigenesis | Growth factors | Medical research | Phenotypes | Wound healing | Cytokines | Invasiveness | Molecular modelling | Medical prognosis | Morphology | Fibrosis | Stem cells | Epigenetics | Tumor suppressor genes | Cancer | Tumors | Index Medicus | Review
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