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Nature Immunology, ISSN 1529-2908, 01/2013, Volume 14, Issue 1, pp. 41 - 51
Journal Article
Science, ISSN 0036-8075, 10/2016, Volume 354, Issue 6308, pp. aad6872 - aad6872
Inhibition or genetic deletion of poly(ADP-ribose) (PAR) polymerase-1 (PARP-1) is protective against toxic insults in many organ systems. The molecular... 
APOPTOSIS | MIGRATION-INHIBITORY FACTOR | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | FACTOR MIF | PARTHANATOS | CYTOKINE | ENZYMATIC-ACTIVITY | TAUTOMERASE | IDENTIFICATION | ENDONUCLEASE-G | Chromatin - metabolism | Mitochondria - enzymology | Oxidative Stress | Glutamic Acid - genetics | Humans | Apoptosis - genetics | Macrophage Migration-Inhibitory Factors - metabolism | Deoxyribonucleases - metabolism | Stroke - genetics | Cell Nucleus - enzymology | Macrophage Migration-Inhibitory Factors - genetics | Base Sequence | DNA Fragmentation | DNA Damage - genetics | Macrophage Migration-Inhibitory Factors - chemistry | Active Transport, Cell Nucleus | Intramolecular Oxidoreductases - metabolism | Nucleic Acid Conformation | Apoptosis Inducing Factor - metabolism | Deoxyribonucleases - chemistry | Amino Acid Sequence | Catalytic Domain | Intramolecular Oxidoreductases - chemistry | DNA, Single-Stranded - metabolism | Poly (ADP-Ribose) Polymerase-1 - metabolism | Apoptosis Inducing Factor - genetics | Mice, Knockout | Stroke - enzymology | Deoxyribonucleases - genetics | Animals | Intramolecular Oxidoreductases - genetics | Neurons - enzymology | Mice | HeLa Cells | Mutation | Glutamic Acid - toxicity | DNA Cleavage | Glutamic Acid - chemistry | Polymerase chain reaction | DNA damage | Cells | Index Medicus | Cell death | Deoxyribonucleic acid | Activation | Nuclease | Inhibition | Damage accumulation | Nuclei | Diseases
Journal Article
Journal Article
Antioxidants & Redox Signaling, ISSN 1523-0864, 04/2011, Volume 14, Issue 7, pp. 1191 - 1202
Macrophage migration inhibitory factor (MIF) is a multifunctional protein that exhibits an intrinsic thiol protein oxidoreductase activity and proinflammatory... 
Original Research Communications | ISCHEMIA-REPERFUSION INJURY | CARDIOMYOCYTE APOPTOSIS | ACTIVE-SITE | PROTEIN-KINASE | THIOREDOXIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | ENDOCRINOLOGY & METABOLISM | FACTOR MIF | MYOCARDIAL-ISCHEMIA | ENZYMATIC-ACTIVITY | CELL-DEATH | REVEALS | Aconitate Hydratase - metabolism | Mitochondria, Heart - metabolism | Reactive Oxygen Species - metabolism | Oxidative Stress | Glutathione - metabolism | Glutathione Reductase - metabolism | Homeodomain Proteins - metabolism | Macrophage Migration-Inhibitory Factors - metabolism | Glutathione Disulfide - metabolism | Myocardial Reperfusion Injury - pathology | Macrophage Migration-Inhibitory Factors - deficiency | Macrophage Migration-Inhibitory Factors - genetics | Myocardium - metabolism | Thioredoxins - metabolism | Intramolecular Oxidoreductases - metabolism | Heart Ventricles - pathology | Superoxide Dismutase - metabolism | Fibroblasts - metabolism | Glutathione Peroxidase - metabolism | Oxidation-Reduction | Cell Survival | Cytochromes c - metabolism | Mice, Inbred C57BL | Cells, Cultured | Hydrogen Peroxide - pharmacology | Myocardium - pathology | Intramolecular Oxidoreductases - deficiency | Mice, Knockout | Myocardial Reperfusion Injury - metabolism | Animals | Heart Ventricles - physiopathology | Intramolecular Oxidoreductases - genetics | Mice | Hemodynamics | Catalase - chemistry | Prevention | Physiological aspects | Oxidative stress | Research | Ischemia | Macrophages | Index Medicus
Journal Article
International Journal of Molecular Sciences, ISSN 1661-6596, 10/2013, Volume 14, Issue 10, pp. 20443 - 20458
Gallic acid is one of the major flavonoids found in plants. It acts as an antioxidant, and seems to have anti-inflammatory, anti-viral, and anti-cancer... 
Dct | Gallic acid | Wnt/β-catenin | MEK/ERK | TRP1 | Melanogenesis | Tyrosinase | Microphthalmia-associated transcription factor (MITF) | PI3K/Akt | CARCINOMA CELLS | catenin | melanogenesis | MITF | Akt | MICROPHTHALMIA GENE-PRODUCT | tyrosinase | gallic acid | HUMAN MELANOCYTES | CHEMISTRY, MULTIDISCIPLINARY | MEK | PHOSPHATIDYLINOSITOL-3-KINASE PATHWAY | PI3K | microphthalmia-associated transcription factor (MITF) | MELANOMA-CELLS | Wnt | NEURAL CREST | TRANSCRIPTION FACTOR | CAMP | ERK | Gallic Acid - pharmacology | Melanoma, Experimental - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Wnt Proteins - metabolism | Melanins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Melanins - biosynthesis | Monophenol Monooxygenase - metabolism | MAP Kinase Signaling System - genetics | Wnt Proteins - genetics | Monophenol Monooxygenase - genetics | Intramolecular Oxidoreductases - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Microphthalmia-Associated Transcription Factor - metabolism | Oxidoreductases - metabolism | Oxidoreductases - genetics | Signal Transduction - genetics | Melanins - genetics | Down-Regulation - drug effects | beta Catenin - metabolism | Down-Regulation - genetics | beta Catenin - genetics | Phosphatidylinositol 3-Kinases - genetics | Animals | MAP Kinase Signaling System - drug effects | Melanoma, Experimental - genetics | Intramolecular Oxidoreductases - genetics | Signal Transduction - drug effects | Cell Line, Tumor | Mice | Microphthalmia-Associated Transcription Factor - genetics | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 06/2010, Volume 465, Issue 7298, pp. 577 - 583
Journal Article