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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 04/2008, Volume 294, Issue 4, pp. G1060 - G1069
Probiotics promote intestinal epithelial integrity and reduce infection and diarrhea. We evaluated the effect of Lactobacillus rhamnosus GG-produced soluble... 
Protein kinase C | Zonula occludens-1 | Intestine | Lactobacillus rhamnosus GG | Mucosal protection | Occludin | zonula occludens-1 | mucosal protection | OXIDATIVE STRESS | PHYSIOLOGY | intestine | DIARRHEA | PERMEABILITY | CYTOSKELETON | CACO-2 CELL MONOLAYER | LACTOBACILLUS GG | TIGHT JUNCTIONS | occludin | IN-VIVO | GROWTH | INTESTINAL BARRIER | GASTROENTEROLOGY & HEPATOLOGY | protein kinase C | Protein Kinase C beta | Intestinal Mucosa - metabolism | Cadherins - metabolism | Nitriles - pharmacology | Humans | Tight Junctions - enzymology | Phosphoproteins - metabolism | Intestinal Mucosa - drug effects | Dose-Response Relationship, Drug | Lactobacillus rhamnosus - chemistry | Time Factors | Protein Kinase C - metabolism | Intestinal Mucosa - enzymology | Indoles - pharmacology | Membrane Proteins - metabolism | Tight Junctions - drug effects | Caco-2 Cells | Hydrogen Peroxide - toxicity | Tight Junctions - metabolism | Butadienes - pharmacology | Protein Kinase C - antagonists & inhibitors | Electric Impedance | Permeability | Probiotics - pharmacology | beta Catenin - metabolism | Probiotics - isolation & purification | Protein Transport | HT29 Cells | Bacterial Proteins - pharmacology | Pyrroles - pharmacology | Zonula Occludens-1 Protein | Mitogen-Activated Protein Kinase 3 - metabolism | Mitogen-Activated Protein Kinases - antagonists & inhibitors | Protein Kinase C-epsilon - metabolism | Inulin - metabolism | Protein Kinase Inhibitors - pharmacology | Bacterial Proteins - isolation & purification | Mitogen-Activated Protein Kinase 1 - metabolism | Mitogen-Activated Protein Kinases - metabolism | Studies | Bacteria | Kinases | Bacterial proteins | Digestive system | Cells | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 03/2010, Volume 298, Issue 3, pp. G352 - G363
Smith F, Clark JE, Overman BL, Tozel CC, Huang JH, Rivier JE, Blisklager AT, Moeser AJ. Early weaning stress impairs development of mucosal barrier function in... 
Weaning age | Mast cells | Corticotropin releasing factor | GASTROINTESTINAL PERMEABILITY | SIGNALING PATHWAYS | PHYSIOLOGY | ION-TRANSPORT | POTASSIUM CHANNELS | mast cells | NIPPOSTRONGYLUS-BRASILIENSIS | weaning age | CORTICOTROPIN-RELEASING-FACTOR | NEONATAL MATERNAL SEPARATION | corticotropin releasing factor | GASTROENTEROLOGY & HEPATOLOGY | RECTAL DISTENSION | IRRITABLE-BOWEL-SYNDROME | MAST-CELL TRYPTASE | Potassium - metabolism | Tryptases - metabolism | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Jejunum - pathology | Receptors, Corticotropin-Releasing Hormone - metabolism | Weaning | Cell Count | Male | Receptors, Glucocorticoid - metabolism | Intestinal Mucosa - drug effects | Jejunum - metabolism | Jejunum - drug effects | Protease Inhibitors - pharmacology | Cromolyn Sodium - pharmacology | Jejunum - physiopathology | Mannitol - metabolism | Mast Cells - metabolism | Female | Hydrocortisone - blood | Potassium Channel Blockers - pharmacology | Animals, Newborn | Stress, Physiological - physiology | Chlorides - pharmacology | Electrophysiological Phenomena - physiology | Corticotropin-Releasing Hormone - blood | Electric Impedance | Permeability | Mast Cells - drug effects | Corticotropin-Releasing Hormone - metabolism | Barium Compounds - pharmacology | Corticotropin-Releasing Hormone - pharmacology | Animals | Receptors, Corticotropin-Releasing Hormone - antagonists & inhibitors | Mast Cells - pathology | Inulin - metabolism | Ion Transport - physiology | Sus scrofa | Electrophysiological Phenomena - drug effects | Intestinal Mucosa - pathology | Hormone receptors | Gastrointestinal diseases | Colorectal diseases | Physiological aspects | Research | Stress (Psychology) | Risk factors | Digestive system | Personal health | Stress | Gastroenterology | Index Medicus | Mucosal Biology
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 07/2011, Volume 301, Issue 1, pp. 50 - 59
The role of mitogen-activated protein kinases (MAPK) in the mechanism of EGF-mediated prevention of acetaldehyde-induced tight junction disruption was... 
c-jun NH | Zona occludens-1 | Epidermal growth factor | Mitogen-activated protein kinase/extracellular signalregulated kinase kinase | Claudin | Tight junction | terminal kinase | Acetaldehyde | Occludin | c-Jun NH2-terminal kinase | OXIDATIVE STRESS | PHYSIOLOGY | mitogen-activated protein kinase/extracellular signal-regulated kinase kinase | ALCOHOLIC LIVER-DISEASE | PROTEIN-TYROSINE PHOSPHORYLATION | PARACELLULAR PERMEABILITY | claudin | INDUCED DISRUPTION | occludin | INDUCED INCREASE | EPIDERMAL-GROWTH-FACTOR | HYDROGEN-PEROXIDE | acetaldehyde | INTESTINAL BARRIER | epidermal growth factor | GASTROENTEROLOGY & HEPATOLOGY | DEPENDENT MECHANISM | tight junction | zona occludens-1 | Caco-2 Cells | Butadienes - pharmacology | Permeability - drug effects | Cadherins - metabolism | Nitriles - pharmacology | Humans | Actins - metabolism | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Phosphoproteins - metabolism | Inulin - physiology | beta Catenin - metabolism | Anthracenes - pharmacology | Claudin-3 | Zonula Occludens-1 Protein | Adherens Junctions - drug effects | Membrane Proteins - metabolism | Pyridines - pharmacology | Acetaldehyde - pharmacology | Epidermal Growth Factor - pharmacology | Extracellular Signal-Regulated MAP Kinases - physiology | Tight Junctions - drug effects | Physiological aspects | Genetic aspects | Properties | Protein kinases | Monomolecular films | Phosphorylation | Permeability | Kinases | Medical treatment | Cells | Index Medicus | mitogen-activated protein kinase | extracellular signal-regulated kinase kinase | Mucosal Biology
Journal Article
2005, Modern Nutrition, ISBN 9780849300592, 359
Inulin and oligofructose are naturally occurring resistant carbohydrates that have a variety of uses as functional food ingredients. In addition to their role... 
Inulin -- Physiological effect | Functional foods | Fructans -- Physiological effect | Fructans | Medicine: General Issues | Inulin
Book
International Journal of Pharmaceutics, ISSN 0378-5173, 03/2016, Volume 500, Issue 1-2, pp. 32 - 41
Micellization offers several advantages for the delivery of water insoluble drugs including a nanoparticulate ‘core–shell’ delivery system for drug targeting.... 
Xenograft | Micelles | Inutec SP1 | Inulin | Paclitaxel | Melanoma | Carbohydrate polymer | MODIFIED CHITOSAN | SYSTEM | BLOCK-COPOLYMERS | SELF-ASSEMBLED NANOPARTICLES | DOXORUBICIN | Inutec SP1 (R) | CARRIERS | CO-DELIVERY | DRUGS | PHARMACOLOGY & PHARMACY | COPOLYMER MICELLES | ANTITUMOR EFFICACY | Hemolysis - drug effects | Paclitaxel - pharmacology | Drug Carriers - therapeutic use | Humans | Melanoma, Experimental - drug therapy | Drug Carriers - administration & dosage | Male | Drug Carriers - chemistry | Inulin - pharmacology | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Inulin - administration & dosage | Antineoplastic Agents, Phytogenic - therapeutic use | Paclitaxel - administration & dosage | Cell Survival - drug effects | Inulin - chemistry | Mice, Inbred C57BL | Melanoma, Experimental - pathology | Antineoplastic Agents, Phytogenic - chemistry | Paclitaxel - therapeutic use | Drug Carriers - pharmacology | Erythrocytes - drug effects | Administration, Intravenous | Animals | Tumor Burden - drug effects | Cell Line, Tumor | Drug Liberation | Hydrophobic and Hydrophilic Interactions | Inulin - therapeutic use | Antineoplastic Agents, Phytogenic - pharmacology | Antimitotic agents | Polymer industry | Antineoplastic agents | Polymers | Ethylene glycol | Polysaccharides | Analysis | Carbamates | Permeability | High performance liquid chromatography | Fructose | Index Medicus
Journal Article
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2017, Volume 152, Issue 1, pp. 124 - 133.e2
Journal Article
JOURNAL OF NUTRITION, ISSN 0022-3166, 05/2016, Volume 146, Issue 5, pp. 949 - 956
Background: Obesity is associated with compromised intestinal barrier function and shifts in gastrointestinal microbiota that may contribute to inflammation.... 
fiber | METABOLIC SYNDROME | INULIN-TYPE FRUCTANS | AKKERMANSIA-MUCINIPHILA | FECAL MICROBIOTA | FATTY-ACIDS | gut microbiota | intestinal permeability | NUTRITION & DIETETICS | CHICORY INULIN | DOUBLE-BLIND | tight junctions | obesity | Intestinal Mucosa - metabolism | Intestinal Mucosa - physiopathology | Bacteria - drug effects | Male | Fructans - pharmacology | RNA, Messenger - metabolism | Obesity - microbiology | Intestinal Absorption | Intestinal Mucosa - drug effects | Occludin - metabolism | Inulin - pharmacology | Occludin - genetics | Oligosaccharides - pharmacology | Feces - microbiology | Bacteria - growth & development | Intestine, Large - metabolism | Monocarboxylic Acid Transporters - metabolism | Diet, High-Fat | Weight Gain - drug effects | Dietary Fiber - pharmacology | Intestine, Large - drug effects | Gene Expression | Obesity - complications | Mice, Inbred C57BL | Oligosaccharides - therapeutic use | Obesity - physiopathology | Bacteria - genetics | Inflammation - etiology | Symporters - metabolism | Animals | Gastrointestinal Microbiome - drug effects | Intestine, Large - pathology | Symporters - genetics | Intestine, Large - physiopathology | Mice, Obese | Monocarboxylic Acid Transporters - genetics | Cellulose - pharmacology | Intestinal Mucosa - pathology | Physiological aspects | Obesity | Fructose metabolism | Research | Microbiota (Symbiotic organisms) | Ribosomal RNA | Genes | Cellulose | Mice | Gene expression | Index Medicus
Journal Article
American Journal of Clinical Nutrition, ISSN 0002-9165, 06/2017, Volume 105, Issue 6, pp. 1544 - 1551
Background: The risk of type 2 diabetes is inversely correlated with plasma concentrations of odd-chain fatty acids [OCFAs; pentadecanoic acid (15: 0) and... 
Long-chain fatty acid | Biomarker | Heptadecanoic | Liver | Pentadecanoic | Phospholipid | Short-chain fatty acid | Propionyl-CoA | Fermentation | Soluble fiber | short-chain fatty acid | long-chain fatty acid | heptadecanoic | LIPID-METABOLISM | liver | MARKER | INULIN | pentadecanoic | HUMANS | RISK | CARBOHYDRATE | SERUM | biomarker | INSULIN SENSITIVITY | NUTRITION & DIETETICS | PLASMA | fermentation | phospholipid | propionyl-CoA | soluble fiber | PENTADECANOIC ACID | Propionates - pharmacology | Dietary Fiber - pharmacology | Propionates - metabolism | Double-Blind Method | Humans | Liver - metabolism | Middle Aged | Diabetes Mellitus, Type 2 - prevention & control | Dietary Fiber - metabolism | Male | Biomarkers - blood | Inulin - pharmacology | Cross-Over Studies | Diabetes Mellitus, Type 2 - blood | Dietary Fiber - therapeutic use | Liver - drug effects | Cell Line, Tumor | Inulin - therapeutic use | Adult | Female | Phospholipids - blood | Fatty Acids - blood | Cellulose - pharmacology | Fatty Acids - biosynthesis | Type 2 diabetes | Nutritional aspects | Research | Fiber in human nutrition | Risk factors | Cellulose | Cell culture | Cellulose propionates | Propionic acid | Diabetes mellitus | Health risks | Chains | Phospholipids | Dietary intake | Hepatoma | Palmitic acid | Fatty acids | Insulin | Fibers | Gas chromatography | Diet | Inulin | Biomarkers | Bioindicators | Dietary fiber | Index Medicus | Abridged Index Medicus
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 12/2000, Volume 279, Issue 6, pp. 1772 - 1781
In patients with amyloid β-related cerebrovascular disorders, e.g., Alzheimer's disease, one finds increased deposition of amyloid peptide (Aβ) and increased... 
Receptor for advanced glycation end product | Platelet endothelial cell adhesion molecule | Amyloid β-peptide | Brain endothelial cells | PHYSIOLOGY | PROTEIN | PERMEABILITY | receptor for advanced glycation end product | ALZHEIMERS-DISEASE | RECEPTOR | brain endothelial cells | MICROGLIAL CELLS | PEPTIDE | CELL BIOLOGY | ADHESION | platelet endothelial cell adhesion molecule | ANGIOPATHY | MONOLAYER | EXPRESSION | amyloid beta-peptide | Endothelium, Vascular - cytology | Inulin - pharmacokinetics | Monocytes - cytology | Amyloid beta-Peptides - pharmacology | Humans | Maleimides - pharmacology | Peptide Fragments - pharmacology | Platelet Endothelial Cell Adhesion Molecule-1 - immunology | Brain - metabolism | Cell Movement - immunology | Dextrans - pharmacokinetics | Brain - blood supply | Adult | Indoles - pharmacology | Receptors, Immunologic - immunology | Capillaries - metabolism | Receptor for Advanced Glycation End Products | Endothelium, Vascular - immunology | Cell Survival - drug effects | Blood-Brain Barrier - immunology | Anti-Inflammatory Agents - pharmacology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Cell Adhesion - drug effects | Antibodies - pharmacology | Cell Adhesion - immunology | Cell Movement - drug effects | HL-60 Cells - cytology | Capillaries - cytology | Endothelium, Vascular - metabolism | Genistein - pharmacology | Anticoagulants - pharmacokinetics | Carbon Radioisotopes | Index Medicus
Journal Article