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Drug Design, Development and Therapy, ISSN 1177-8881, 10/2015, Volume 9, pp. 5737 - 5747
Berberine (BBR), an isoquinoline alkaloid mainly isolated from plants of Berberidaceae family, is extensively used to treat gastrointestinal infections in... 
Berberine | hERG | Cardiotoxicity | Cavoline-1 | Pharmacological rescue | LQTS | TRAFFICKING INHIBITION | DOFETILIDE | CHEMISTRY, MEDICINAL | CHOLESTEROL | BLOCK | berberine | cardiotoxicity | AFFINITY | cavoline-1 | PROTEIN TRAFFICKING | PHARMACOLOGY & PHARMACY | LONG QT SYNDROME | MUTATIONS | BINDING | pharmacological rescue | POTASSIUM CHANNEL | Terfenadine - pharmacology | Tyrosine | Phenylalanine | Humans | Ether-A-Go-Go Potassium Channels - metabolism | Terfenadine - analogs & derivatives | Stilbenes - pharmacology | ERG1 Potassium Channel | Ether-A-Go-Go Potassium Channels - genetics | Action Potentials | Caveolin 1 - metabolism | Dose-Response Relationship, Drug | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Berberine - pharmacology | Transfection | RNA Interference | HEK293 Cells | Resveratrol | Cell Membrane - metabolism | Kinetics | Mutation | Cell Membrane - drug effects | Potassium Channel Blockers - pharmacology | Ion transport | Ion channels | Genetic aspects | Gene expression | Properties | Health aspects | Caveolin-1 | HERG protein | Caveolin | Action potential | Cardiomyocytes | Pharmacology | Cell membranes | Fexofenadine | Cell surface | Cholesterol | Proteins | Temperature effects | Penicillin | Regulatory mechanisms (biology) | Long QT syndrome | Potassium channels (voltage-gated) | Potassium | Binding sites
Journal Article
Neuron, ISSN 0896-6273, 2011, Volume 70, Issue 3, pp. 482 - 494
Transient receptor potential melastatin-3 (TRPM3) is a broadly expressed Ca -permeable nonselective cation channel. Previous work has demonstrated robust... 
TEMPERATURE | TRPV4 | CATION CHANNEL | ION-CHANNEL | PREGNENOLONE SULFATE | VANILLOID RECEPTOR-1 | COLD | CAPSAICIN-RECEPTOR | NEUROSCIENCES | MICE LACKING | EVOKED ACTIVATION | Hyperalgesia - chemically induced | Telemetry - methods | Calcium - metabolism | Capsaicin - pharmacology | Humans | Ganglia, Spinal - cytology | Transient Receptor Potential Channels - deficiency | Inflammation - metabolism | Time Factors | Behavior, Animal - drug effects | Sensory Receptor Cells - metabolism | Disease Models, Animal | Membrane Potentials - drug effects | Plant Oils - pharmacology | Trigeminal Ganglion - cytology | Mice, Knockout | Blood Glucose - drug effects | Patch-Clamp Techniques | Hyperalgesia - genetics | Transient Receptor Potential Channels - genetics | Gene Expression Regulation - radiation effects | TRPM Cation Channels - genetics | Blood Glucose - genetics | Mice | Inflammation - chemically induced | Mustard Plant | Pain Threshold - physiology | TRPM Cation Channels - deficiency | Membrane Potentials - genetics | Pregnenolone - adverse effects | Dose-Response Relationship, Drug | Transfection - methods | Bridged Bicyclo Compounds, Heterocyclic - therapeutic use | Freund's Adjuvant - adverse effects | Pain Threshold - drug effects | Nifedipine - pharmacology | Hot Temperature - adverse effects | Hyperalgesia - metabolism | Gene Expression Regulation - genetics | Mice, Inbred C57BL | Pain Measurement - drug effects | Calcium Channel Blockers - pharmacology | Pain Measurement - methods | Animals | Sensory Receptor Cells - drug effects | TRPM Cation Channels - antagonists & inhibitors | Hyperalgesia - drug therapy | TRPA1 Cation Channel | Inflammation - genetics | Acrylamides - therapeutic use | TRPM Cation Channels - metabolism | Cell Line, Transformed | Chemotherapy | Progesterone | Sulfates | Cancer | Heat | Behavior | Cold | Neurons | Rodents
Journal Article
Nature Medicine, ISSN 1078-8956, 10/2012, Volume 18, Issue 10, pp. 1575 - 1579
Journal Article