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Journal Article
Cancer Chemotherapy and Pharmacology, ISSN 0344-5704, 12/2018, Volume 82, Issue 6, pp. 1021 - 1029
NK012 is a polymeric micelle formulation of SN-38, the active metabolite of irinotecan. We evaluated the efficacy and safety of NK012 in Japanese patients with... 
SN-38 | Medicine & Public Health | Colorectal cancer | Oncology | Cancer Research | NK012 | Phase II | Pharmacology/Toxicology | Polymeric micelle | SYNERGISTIC ANTITUMOR-ACTIVITY | INTESTINAL MICROFLORA | COMBINATION | LUNG-CANCER | POLYMORPHISMS | IRINOTECAN HYDROCHLORIDE CPT-11 | ONCOLOGY | CAMPTOTHECIN | MOUSE MODEL | BETA-GLUCURONIDASE | JAPANESE | PHARMACOLOGY & PHARMACY | Irinotecan - administration & dosage | Humans | Middle Aged | Neoplasm Recurrence, Local - drug therapy | Male | Irinotecan - therapeutic use | Drug Carriers - chemistry | Neoplasm Recurrence, Local - pathology | Glucuronosyltransferase - genetics | Neoplasm Metastasis | Colorectal Neoplasms - drug therapy | Micelles | Female | Colorectal Neoplasms - metabolism | Topoisomerase I Inhibitors - pharmacokinetics | Neoplasm Recurrence, Local - metabolism | Kaplan-Meier Estimate | Topoisomerase I Inhibitors - administration & dosage | Irinotecan - pharmacokinetics | Polymorphism, Genetic | Topoisomerase I Inhibitors - therapeutic use | Progression-Free Survival | Polymers - chemistry | Infusions, Intravenous | Colorectal Neoplasms - pathology | Cancer patients | Care and treatment | Relapse | Resveratrol | Metastasis | Diseases | Colorectal carcinoma | Diarrhea | Survival | Patients | Incidence | Metastases | Irinotecan | Chemotherapy | Oxaliplatin | Genotypes | Neutropenia | Cancer | Original
Journal Article
Journal of pharmacological sciences, ISSN 1347-8613, 2019, Volume 140, Issue 1, pp. 20 - 25
Journal Article
CURRENT MEDICINAL CHEMISTRY, ISSN 0929-8673, 2019, Volume 26, Issue 12, pp. 2085 - 2107
Journal Article
Journal of clinical pharmacology, ISSN 0091-2700, 01/2019, Volume 59, Issue 1, pp. 20 - 34
Journal Article
The lancet oncology, ISSN 1470-2045, 2014, Volume 15, Issue 10, pp. 1065 - 1075
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Journal Article
Journal of Neuro-Oncology, ISSN 0167-594X, 2/2018, Volume 136, Issue 3, pp. 475 - 484
Journal Article
The New England journal of medicine, ISSN 1533-4406, 2019, Volume 381, Issue 17, pp. 1632 - 1643
Journal Article
Cancer chemotherapy and pharmacology, ISSN 1432-0843, 2018, Volume 83, Issue 1, pp. 169 - 178
Journal Article
Journal Article