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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 10/2012, Volume 303, Issue 7, pp. G775 - G785
Journal Article
Gastroenterology, ISSN 0016-5085, 2013, Volume 144, Issue 5, pp. 903 - 911.e3
Journal Article
Gut, ISSN 0017-5749, 05/2014, Volume 63, Issue 5, pp. 744 - 752
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 148, Issue 6, pp. 1158 - 1174.e4
Journal Article
Gastroenterology, ISSN 0016-5085, 2007, Volume 132, Issue 3, pp. 913 - 920
Background & Aims: We set out to test the hypothesis that irritable bowel syndrome (IBS) is characterized by an augmented cellular immune response with... 
Gastroenterology and Hepatology | PSYCHOLOGICAL STRESS | VISCERAL SENSORY FUNCTION | IFN-GAMMA | NECROSIS-FACTOR-ALPHA | TNF-ALPHA | CHRONIC-FATIGUE-SYNDROME | GASTROENTEROLOGY & HEPATOLOGY | FUNCTIONAL GASTROINTESTINAL DISORDERS | HELICOBACTER-PYLORI | BLOOD MONONUCLEAR-CELLS | RAT MODEL | Leukocytes, Mononuclear - metabolism | Humans | Male | Case-Control Studies | Depression - etiology | Depression - metabolism | Psychiatric Status Rating Scales | Leukocytes, Mononuclear - immunology | Inflammation Mediators - metabolism | Irritable Bowel Syndrome - immunology | Irritable Bowel Syndrome - psychology | Adult | Female | Surveys and Questionnaires | Interleukin-1beta - biosynthesis | Anxiety - metabolism | Severity of Illness Index | Irritable Bowel Syndrome - metabolism | Leukocytes, Mononuclear - drug effects | Enzyme-Linked Immunosorbent Assay | Cells, Cultured | Anxiety - immunology | Lipopolysaccharides - pharmacology | Interleukin-6 - biosynthesis | Immunity, Cellular | Tumor Necrosis Factor-alpha - biosynthesis | Anxiety - etiology | Cytokines - biosynthesis | Depression - immunology | Care and treatment | Irritable bowel syndrome | C-IBS, constipation-predominant irritable bowel syndrome | HPA, hypothalamic-pituitary-adrenal | IBS, irritable bowel syndrome | TNF, tumor necrosis factor | IL, interleukin | M-IBS, mixed IBS | HCs, healthy controls | LPS, lipopolysaccharide | D-IBS, diarrhea-predominant irritable bowel syndrome | PBMCs, peripheral blood mononuclear cells | PI-IBS, postinfectious IBS
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 150, Issue 4, pp. 875 - 887.e9
Abstract Background & Aims Histamine sensitizes the nociceptor TRPV1 and has been shown to contribute to visceral hypersensitivity in animals. We investigated... 
Gastroenterology and Hepatology | Sensory Neurons | Drug | Transient Receptor Potential Cation Channel Subfamily V Member 1 | Treatment | PROTEIN-KINASE-C | LINACLOTIDE | COLONIC HYPERSENSITIVITY | DISORDERS | MUTATIONAL ANALYSIS | POTENTIAL VANILLOID 1 | CLINICAL-TRIALS | BINDING-SITE | PLACEBO-CONTROLLED TRIAL | ION CHANNELS | GASTROENTEROLOGY & HEPATOLOGY | Abdominal Pain - prevention & control | Humans | Middle Aged | Male | Young Adult | Receptors, Histamine H1 - drug effects | TRPV Cation Channels - metabolism | Receptors, Histamine H1 - metabolism | Time Factors | Irritable Bowel Syndrome - diagnosis | Rectum - innervation | Pain Threshold - drug effects | Adult | Female | Surveys and Questionnaires | Neurons - metabolism | Neurons - drug effects | Analgesics - adverse effects | Analgesics - therapeutic use | Irritable Bowel Syndrome - metabolism | Butyrophenones - therapeutic use | Double-Blind Method | Abdominal Pain - physiopathology | Irritable Bowel Syndrome - drug therapy | Treatment Outcome | Abdominal Pain - metabolism | Irritable Bowel Syndrome - physiopathology | Remission Induction | Butyrophenones - adverse effects | Histamine H1 Antagonists - adverse effects | Belgium | Histamine H1 Antagonists - therapeutic use | Biopsy | Calcium Signaling - drug effects | Piperidines - therapeutic use | Piperidines - adverse effects | Adolescent | Gastrointestinal Agents - therapeutic use | Quality of Life | Aged | Gastrointestinal Agents - adverse effects | Pain Measurement | Receptor Cross-Talk - drug effects | Drugs | Histamine | Care and treatment | Drug delivery systems | Gastrointestinal diseases | Irritable bowel syndrome | Research institutes | Vehicles
Journal Article
The American Journal of Gastroenterology, ISSN 0002-9270, 07/2011, Volume 106, Issue 7, pp. 1290 - 1298
Journal Article
Journal Article