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1. Full Text Pancreatic β-cell identity, glucose sensing and the control of insulin secretion
by Rutter, Guy A and Pullen, Timothy J and Hodson, David J and Martinez-Sanchez, Aida
Biochemical journal, ISSN 0264-6021, 03/2015, Volume 466, Issue 2, pp. 203 - 218
Recombinant probe | Secretion | Imaging | Beta cell | Electrophysiology | Diabetes | Glucose | Islet | Pancreas | Insulin | Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Mitochondria - enzymology | Islets of Langerhans - physiology | Islets of Langerhans - pathology | Humans | Secretory Pathway | Cell Dedifferentiation | Mitochondria - metabolism | Diabetes Mellitus, Type 2 - blood | Insulin - metabolism | Insulin-Secreting Cells - metabolism | Animals | Diabetes Mellitus, Type 2 - physiopathology | Models, Biological | Islets of Langerhans - cytology | Islets of Langerhans - physiopathology | Insulin-Secreting Cells - cytology | Diabetes Mellitus, Type 2 - pathology | Insulin-Secreting Cells - pathology | Blood Glucose - metabolism | Insulin Secretion | Index Medicus
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2. Full Text Molecular Physiology of Mammalian Glucokinase
by Iynedjian, P B and Iynedjian, P B
Cellular and molecular life sciences : CMLS, ISSN 1420-682X, 01/2009, Volume 66, Issue 1, pp. 27 - 42
Biochemistry, general | hepatocyte | insulin | Biomedicine general | Cell Biology | Life Sciences | islet of Langerhans | MODY | Life Sciences, general | Glucokinase | diabetes | glucose metabolism | hexokinase | Glucose metabolism | Hepatocyte | Islet of Langerhans | Diabetes | Insulin | Hexokinase | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Hexokinase - physiology | Liver - enzymology | Insulin - physiology | Islets of Langerhans - enzymology | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Type 2 - enzymology | Gene Expression Regulation | Brain - enzymology | Congenital Hyperinsulinism - enzymology | Congenital Hyperinsulinism - genetics | Homeostasis - physiology | Glucose - metabolism | Mitochondrial Membranes - enzymology | Adaptor Proteins, Signal Transducing - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Hexokinase - genetics | Hexokinase - chemistry | Homeostasis - genetics | Anopheles | Isoenzymes | Analysis | Physiological aspects | Glucose | Gene expression | Dextrose | Proteins | Enzymes | Biochemistry | Molecular biology | Index Medicus | Review
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3. Full Text Co-expression of the homologous proteases fibroblast activation protein and dipeptidyl peptidase-IV in the adult human Langerhans islets
by Busek, Petr and Busek, Petr and Hrabal, Petr and Hrabal, Petr and Fric, Premysl and Fric, Premysl and Sedo, Aleksi and Sedo, Aleksi
Histochemistry and cell biology, ISSN 0948-6143, 5/2015, Volume 143, Issue 5, pp. 497 - 504
Biochemistry, general | Biomedicine | Langerhans islets | Gliptins | Diabetes | Developmental Biology | Pancreas | Biomedicine general | Fibroblast activation protein | Cell Biology | Dipeptidyl peptidase | Life Sciences & Biomedicine | Microscopy | Technology | Science & Technology | Gelatinases - analysis | Immunohistochemistry | Microscopy, Confocal | Glucagon-Secreting Cells - enzymology | Islets of Langerhans - enzymology | Humans | Islets of Langerhans - cytology | Adult | Dipeptidyl Peptidase 4 - analysis | Glucagon - analysis | Membrane Proteins - analysis | Serine Endopeptidases - analysis | Glucagon | Proteases | Cells | Proteins | Peptides | Gene expression | Index Medicus
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4. Full Text Heme Oxygenase-1 Induction in Islet Cells Results in Protection From Apoptosis and Improved In Vivo Function After Transplantation
by Antonello Pileggi and R. Damaris Molano and Thierry Berney and Pierre Cattan and Caterina Vizzardelli and Robert Oliver and Christopher Fraker and Camillo Ricordi and Ricardo L. Pastori and Fritz H. Bach and Luca Inverardi
Diabetes, ISSN 0012-1797, 09/2001, Volume 50, Issue 9, pp. 1983 - 1991
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Biological and medical sciences | Endocrinopathies | Management. Various non-drug treatments. Langerhans islet grafts | Diabetes. Impaired glucose tolerance | Medical sciences | Endocrine pancreas. Apud cells (diseases) | Islets of Langerhans - drug effects | Up-Regulation | Islets of Langerhans - physiology | Islets of Langerhans - enzymology | Mice, Inbred C57BL | Protoporphyrins - pharmacology | Enzyme Induction | Male | Reference Values | Transplantation, Isogeneic | Membrane Proteins | Animals | Time Factors | Tumor Necrosis Factor-alpha - physiology | Islets of Langerhans Transplantation | Heme Oxygenase-1 | Mice | Apoptosis - physiology | Tumor Cells, Cultured | Blood Glucose - metabolism | Heme Oxygenase (Decyclizing) - metabolism | Oxidases | Evaluation | Cell death | Heme | Islands of Langerhans | Transplantation of organs, tissues, etc | Research | Index Medicus | Abridged Index Medicus
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5. Full Text Extracellularly Regulated Kinases 1/2 (p44/42 Mitogen-Activated Protein Kinases) Phosphorylate Synapsin I and Regulate Insulin Secretion in the MIN6 β-Cell Line and Islets of Langerhans
by Longuet, Christine and Broca, Christophe and Costes, Safia and Hani, El Habib and Bataille, Dominique and Dalle, Stéphane
Endocrinology (Philadelphia), ISSN 0013-7227, 02/2005, Volume 146, Issue 2, pp. 643 - 654
Life Sciences & Biomedicine | Endocrinology & Metabolism | Science & Technology | Fundamental and applied biological sciences. Psychology | Vertebrates: endocrinology | Biological and medical sciences | Cytoplasm - enzymology | Islets of Langerhans - drug effects | Mitogen-Activated Protein Kinase 3 - genetics | Rats, Wistar | Islets of Langerhans - enzymology | Rats | Male | Glucose - pharmacology | Synapsins - metabolism | Cell Nucleus - enzymology | Insulin - metabolism | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Islets of Langerhans - metabolism | Islets of Langerhans - cytology | Mitogen-Activated Protein Kinase 1 - genetics | Cell Line, Tumor | RNA, Small Interfering | Phosphorylation - drug effects | Pancreatic Neoplasms | Insulin Secretion | Mitogen-Activated Protein Kinase 1 - metabolism | Index Medicus | Abridged Index Medicus | Life Sciences | Human health and pathology | Endocrinology and metabolism
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6. Full Text Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK
by Harding, Heather P and Zyryanova, Alisa F and Ron, David
The Journal of biological chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 53, pp. 44338 - 44344
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Islets of Langerhans - drug effects | eIF-2 Kinase - metabolism | Endoplasmic Reticulum - metabolism | Insulin-Secreting Cells - metabolism | Islets of Langerhans - metabolism | Protein Folding - drug effects | Endoplasmic Reticulum - drug effects | Islets of Langerhans - cytology | Eukaryotic Initiation Factor-2 - metabolism | Insulin - genetics | eIF-2 Kinase - genetics | Endoplasmic Reticulum - enzymology | Unfolded Protein Response - drug effects | Islets of Langerhans - enzymology | Cells, Cultured | Rats | eIF-2 Kinase - antagonists & inhibitors | Mice, Knockout | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Insulin - chemistry | Eukaryotic Initiation Factor-2 - genetics | Glucose - metabolism | Protein Biosynthesis - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | In Vitro Techniques | Insulin-Secreting Cells - enzymology | Index Medicus | Protein Misfolding | Protein Synthesis | Translation Initiation | Endoplasmic Reticulum Stress | Insulin Synthesis | Pancreatic Islets | Insulin Metabolism | Unfolded Protein Response | Cell Biology
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7. Full Text Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice
by Pepper, Andrew R and Bruni, Antonio and Pawlick, Rena and Wink, John and Rafiei, Yasmin and Gala-Lopez, Boris and Bral, Mariusz and Abualhassan, Nasser and Kin, Tatsuya and Shapiro, A.M James
Transplantation, ISSN 0041-1337, 10/2017, Volume 101, Issue 10, pp. 2321 - 2329
Transplantation | Immunology | Life Sciences & Biomedicine | Surgery | Science & Technology | Islets of Langerhans - drug effects | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Diabetes Mellitus, Experimental - surgery | Streptozocin | Diabetes Mellitus, Type 1 - surgery | Humans | Caspase 3 - metabolism | Male | Islets of Langerhans - surgery | Diabetes Mellitus, Experimental - blood | Heterografts | Time Factors | Amino Acid Chloromethyl Ketones - pharmacology | Diabetes Mellitus, Type 1 - chemically induced | Diabetes Mellitus, Experimental - chemically induced | Cell Survival - drug effects | Islets of Langerhans - pathology | Islets of Langerhans - enzymology | Tissue Culture Techniques | Mice, Inbred C57BL | Biomarkers - blood | Islets of Langerhans Transplantation - methods | Animals | Signal Transduction - drug effects | Diabetes Mellitus, Type 1 - blood | Enzyme Activation | Blood Glucose - metabolism | Graft Survival - drug effects | Index Medicus
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