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1. Full Text SIRT4 Inhibits Glutamate Dehydrogenase and Opposes the Effects of Calorie Restriction in Pancreatic β Cells
by Haigis, Marcia C and Haigis, Kevin M and Mostoslavsky, Raul and Fahie, Kamau and Christodoulou, Danos C and Murphy, Andrew J and Valenzuela, David M and Yancopoulos, George D and Karow, Margaret and Blander, Gil and Wolberger, Cynthia and Prolla, Tomas A and Weindruch, Richard and Alt, Frederick W and Guarente, Leonard
Cell, ISSN 0092-8674, 2006, Volume 126, Issue 5, pp. 941 - 954
Sir2 is an NAD-dependent deacetylase that connects metabolism with longevity in yeast, flies, and worms. Mammals have seven Sir2 homologs (SIRT1–7). We show... 
Islets of Langerhans - drug effects | Mitochondria - enzymology | RNA, Small Interfering - genetics | Caloric Restriction | Humans | Adenosine Diphosphate Ribose - metabolism | Amino Acids - pharmacology | Transfection | Sirtuin 1 | Glutamine - pharmacology | Sirtuins - genetics | Glutamate Dehydrogenase - metabolism | NAD - metabolism | Islets of Langerhans - enzymology | Down-Regulation | Glucose - pharmacology | Glutamate Dehydrogenase - genetics | Mice, Knockout | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Cell Line, Tumor | Mice | Protein Processing, Post-Translational | Sirtuins - metabolism | Insulin-Secreting Cells - enzymology | RNA, Small Interfering - metabolism
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2. Full Text Molecular Physiology of Mammalian Glucokinase
by Iynedjian, P B and Iynedjian, P B
Cellular and Molecular Life Sciences, ISSN 1420-682X, 01/2009, Volume 66, Issue 1, pp. 27 - 42
The glucokinase (GCK) gene was one of the first candidate genes to be identified as a human “diabetes gene". Subsequently, important advances were made in... 
Biochemistry, general | hepatocyte | insulin | Biomedicine general | Cell Biology | Life Sciences | islet of Langerhans | MODY | Life Sciences, general | Glucokinase | diabetes | glucose metabolism | hexokinase | Glucose metabolism | Hepatocyte | Islet of Langerhans | Diabetes | Insulin | Hexokinase | INSULIN-DEPENDENT INDUCTION | HEPATIC GLYCOGEN-SYNTHESIS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ELEMENT-BINDING PROTEIN-1C | YOUNG TYPE-2 MODY-2 | BETA-CELL GLUCOKINASE | CELL BIOLOGY | PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA | GENE-EXPRESSION | REGULATORY PROTEIN | LIVER-X-RECEPTOR | GROWTH-FACTOR-I | Hexokinase - physiology | Liver - enzymology | Insulin - physiology | Islets of Langerhans - enzymology | Diabetes Mellitus, Type 2 - genetics | Humans | Diabetes Mellitus, Type 2 - enzymology | Gene Expression Regulation | Brain - enzymology | Congenital Hyperinsulinism - enzymology | Congenital Hyperinsulinism - genetics | Homeostasis - physiology | Glucose - metabolism | Mitochondrial Membranes - enzymology | Adaptor Proteins, Signal Transducing - metabolism | Diabetes Mellitus, Type 2 - drug therapy | Hexokinase - genetics | Hexokinase - chemistry | Homeostasis - genetics | Anopheles | Isoenzymes | Analysis | Physiological aspects | Glucose | Gene expression | Dextrose | Proteins | Enzymes | Biochemistry | Molecular biology | Review
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3. Full Text Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca2+, Leading to Induction of Endoplasmic Reticulum Stress in Pancreatic β-Cells
by Alessandra K. Cardozo and Fernanda Ortis and Joachim Storling and Ying-Mei Feng and Joanne Rasschaert and Morten Tonnesen and Françoise Van Eylen and Thomas Mandrup-Poulsen and André Herchuelz and Décio L. Eizirik
Diabetes, ISSN 0012-1797, 02/2005, Volume 54, Issue 2, pp. 452 - 461
Cytokines Downregulate the Sarcoendoplasmic Reticulum Pump Ca 2+ ATPase 2b and Deplete Endoplasmic Reticulum Ca 2+ , Leading to Induction of Endoplasmic... 
SKELETAL-MUSCLE | ACTIVATION | UNFOLDED PROTEIN RESPONSE | MESSENGER-RNA | INDUCED APOPTOSIS | ENDOCRINOLOGY & METABOLISM | NITRIC-OXIDE | MAMMALIAN-CELLS | ISLET CELLS | EXPRESSION | INDUCED GENES | Endoplasmic Reticulum - enzymology | Gene Expression Regulation, Enzymologic - drug effects | Islets of Langerhans - drug effects | Islets of Langerhans - physiology | Rats, Wistar | Islets of Langerhans - enzymology | Sarcoplasmic Reticulum - drug effects | Oxidative Stress - physiology | Rats | Calcium-Transporting ATPases - genetics | DNA Primers | Reverse Transcriptase Polymerase Chain Reaction | Sarcoplasmic Reticulum - enzymology | Animals | Calcium - physiology | Base Sequence | Endoplasmic Reticulum - drug effects | Thapsigargin - pharmacology | Cytokines - pharmacology
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4. Full Text Pancreatic insulin content regulation by the Estrogen receptor ERα
by Alonso-Magdalena, Paloma and Ropero, Ana B and Carrera, M. Pilar and Cederroth, Christopher R and Baquié, Mathurin and Gauthier, Benoit R and Nef, Serge and Stefani, Enrico and Nadal, Angel
PLoS ONE, ISSN 1932-6203, 04/2008, Volume 3, Issue 4, pp. e2069 - e2069
The function of pancreatic beta-cells is the synthesis and release of insulin, the main hormone involved in blood glucose homeostasis. Estrogen receptors, ER... 
MULTIDISCIPLINARY SCIENCES | Islets of Langerhans - drug effects | Benzhydryl Compounds | Rats, Wistar | Islets of Langerhans - enzymology | Mice, Inbred C57BL | Rats | Male | Glucose - pharmacology | Mice, Knockout | Gene Expression Regulation - drug effects | Insulin - metabolism | Animals | Estrogen Receptor alpha - agonists | Estrogen Receptor beta - agonists | Mitogen-Activated Protein Kinase 3 - metabolism | Calcium Signaling - drug effects | Islets of Langerhans - metabolism | Estrogen Receptor alpha - metabolism | Mice | Insulin - genetics | Insulin Secretion | Estradiol - pharmacology | Mitogen-Activated Protein Kinase 1 - metabolism | Phenols - pharmacology | Estrogens | Estrogen | Homeostasis | Estrogen receptors | 17β-Estradiol | Biosynthesis | Hormones | Glucose | Kinases | Blood | Medical schools | Glucose metabolism | Receptors | Rodents | Physiology | Pancreas | Drug dosages | Extracellular signal-regulated kinase | Polyethylene terephthalate | Metabolism | Gene expression | Insulin | Medicine | Pregnancy | Bisphenol A | Sex hormones | Phenols | Ligands | Insulin resistance | Diabetes
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5. Full Text Uncoupling proteostasis and development in vitro with a small molecule inhibitor of the pancreatic endoplasmic reticulum kinase, PERK
by Harding, Heather P and Zyryanova, Alisa F and Ron, David
Journal of Biological Chemistry, ISSN 0021-9258, 12/2012, Volume 287, Issue 53, pp. 44338 - 44344
Loss-of-function mutations in EIF2AK3, encoding the pancreatic endoplasmic reticulum (ER) kinase, PERK, are associated with dysfunction of the endocrine... 
MESSENGER-RNA TRANSLATION | UNFOLDED PROTEIN RESPONSE | ALPHA-SUBUNIT | INITIATION | PHOSPHORYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENE-EXPRESSION | EIF2AK3 | MAINTAINS | REINITIATION | INTEGRATED STRESS-RESPONSE | Islets of Langerhans - drug effects | eIF-2 Kinase - metabolism | Endoplasmic Reticulum - metabolism | Insulin-Secreting Cells - metabolism | Islets of Langerhans - metabolism | Protein Folding - drug effects | Endoplasmic Reticulum - drug effects | Islets of Langerhans - cytology | Eukaryotic Initiation Factor-2 - metabolism | Insulin - genetics | eIF-2 Kinase - genetics | Endoplasmic Reticulum - enzymology | Unfolded Protein Response - drug effects | Islets of Langerhans - enzymology | Cells, Cultured | Rats | eIF-2 Kinase - antagonists & inhibitors | Mice, Knockout | Insulin - metabolism | Animals | Insulin-Secreting Cells - drug effects | Insulin - chemistry | Eukaryotic Initiation Factor-2 - genetics | Glucose - metabolism | Protein Biosynthesis - drug effects | Mice | Protein Kinase Inhibitors - pharmacology | In Vitro Techniques | Insulin-Secreting Cells - enzymology | Protein Misfolding | Protein Synthesis | Translation Initiation | Endoplasmic Reticulum Stress | Insulin Synthesis | Pancreatic Islets | Insulin Metabolism | Unfolded Protein Response | Cell Biology
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6. Full Text Synthesis and Characterization of Urofuranoic Acids: In Vivo Metabolism of 2‑(2-Carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic Acid (CMPF) and Effects on in Vitro Insulin Secretion
by Nagy, Edith and Liu, Ying and Prentice, Kacey J and Sloop, Kyle W and Sanders, Phillip E and Batchuluun, Battsetseg and Hammond, Craig D and Wheeler, Michael B and Durham, Timothy B
Journal of Medicinal Chemistry, ISSN 0022-2623, 03/2017, Volume 60, Issue 5, pp. 1860 - 1875
CMPF (2-(2-carboxyethyl)-4-methyl-5-propylfuran-3-carboxylic acid) is a metabolite that circulates at high concentrations in type 2 and gestational diabetes... 
Islets of Langerhans - drug effects | Islets of Langerhans - enzymology | Carboxylic Acids - chemical synthesis | Furans - pharmacology | Humans | Cytochrome P-450 Enzyme System - metabolism | Insulin - metabolism | Animals | Islets of Langerhans - metabolism | Mice | Furans - chemical synthesis | Insulin Secretion | Carboxylic Acids - pharmacology
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7. Full Text Anthocyanins from Chinese Bayberry Extract Protect β Cells from Oxidative Stress-Mediated Injury via HO-1 Upregulation
by Zhang, Bo and Kang, Muxing and Xie, Qiuping and Xu, Bing and Sun, Chongde and Chen, Kunsong and Wu, Yulian
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 01/2011, Volume 59, Issue 2, pp. 537 - 545
Oxidative stress plays a pivotal role during the islet transplantation procedure, and antioxidant supplementation may protect grafts against oxidative injury.... 
Bioactive Constituents | Anthocyanins | apoptosis | Chinese bayberry | heme oxygenase-1 | oxidative stress | cyanidin-3-O-glucoside | FRUITS | ACTIVATION | HEME OXYGENASE-1 EXPRESSION | FOOD SCIENCE & TECHNOLOGY | ISLET TRANSPLANTATION | PANCREATIC-ISLETS | FACTOR-2 | CARBON-MONOXIDE | PATHWAY | ENDOTHELIAL-CELLS | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | PC12 CELLS | Islets of Langerhans - drug effects | Anthocyanins - pharmacology | Heme Oxygenase-1 - metabolism | Islets of Langerhans - enzymology | Drugs, Chinese Herbal - pharmacology | Rats | Mice, Inbred ICR | Up-Regulation - drug effects | Heme Oxygenase-1 - genetics | Myrica - chemistry | Insulin-Secreting Cells - metabolism | Animals | Insulin-Secreting Cells - drug effects | Islets of Langerhans - metabolism | Protective Agents - pharmacology | Islets of Langerhans - cytology | Cell Line, Tumor | Mice | Oxidative Stress - drug effects | Insulin-Secreting Cells - enzymology
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8. Full Text Engraftment Site and Effectiveness of the Pan-Caspase Inhibitor F573 to Improve Engraftment in Mouse and Human Islet Transplantation in Mice
by Pepper, Andrew R and Bruni, Antonio and Pawlick, Rena and Wink, John and Rafiei, Yasmin and Gala-Lopez, Boris and Bral, Mariusz and Abualhassan, Nasser and Kin, Tatsuya and Shapiro, A.M James
Transplantation, ISSN 0041-1337, 10/2017, Volume 101, Issue 10, pp. 2321 - 2329
BACKGROUNDIslet transplantation is an effective therapy in type 1 diabetes and recalcitrant hypoglycemia. However, there is an ongoing need to circumvent islet... 
SURVIVAL | SURGERY | KIDNEY CAPSULE | PANCREATIC-ISLETS | IMMUNOLOGY | TRANSPLANTATION | Islets of Langerhans - drug effects | Caspase Inhibitors - pharmacology | Apoptosis - drug effects | Diabetes Mellitus, Experimental - surgery | Streptozocin | Diabetes Mellitus, Type 1 - surgery | Humans | Caspase 3 - metabolism | Male | Islets of Langerhans - surgery | Diabetes Mellitus, Experimental - blood | Heterografts | Time Factors | Amino Acid Chloromethyl Ketones - pharmacology | Diabetes Mellitus, Type 1 - chemically induced | Diabetes Mellitus, Experimental - chemically induced | Cell Survival - drug effects | Islets of Langerhans - pathology | Islets of Langerhans - enzymology | Tissue Culture Techniques | Mice, Inbred C57BL | Biomarkers - blood | Islets of Langerhans Transplantation - methods | Animals | Signal Transduction - drug effects | Diabetes Mellitus, Type 1 - blood | Enzyme Activation | Blood Glucose - metabolism | Graft Survival - drug effects
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9. Full Text Vildagliptin, a Dipeptidyl Peptidase-IV Inhibitor, Improves Model-Assessed β-Cell Function in Patients with Type 2 Diabetes
by Mari, A and Sallas, W. M and He, Y. L and Watson, C and Ligueros-Saylan, M and Dunning, B. E and Deacon, C. F and Holst, J. J and Foley, J. E
The Journal of Clinical Endocrinology & Metabolism, ISSN 0021-972X, 08/2005, Volume 90, Issue 8, pp. 4888 - 4894
Aims/Hypothesis: The dipeptidyl peptidase IV inhibitor, vildagliptin, increases levels of intact glucagon-like peptide-1 (GLP-1) and improves glycemic control... 
MEDIATED GLUCOSE-UPTAKE | GLP-1 | GLUCAGON-LIKE PEPTIDE-1 | TOLERANCE | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | ENTEROINSULAR AXIS | SENSITIVITY | 7-36 AMIDE | METABOLIC-CONTROL | POLYPEPTIDE | Islets of Langerhans - drug effects | C-Peptide - blood | Humans | Middle Aged | Dipeptidyl Peptidase 4 | Male | Diabetes Mellitus, Type 2 - metabolism | Adenosine Deaminase Inhibitors | Insulin - blood | Enzyme Inhibitors - administration & dosage | Islets of Langerhans - metabolism | Pyrrolidines | Adult | Female | Nitriles | Adamantane - administration & dosage | Insulin Secretion | Adamantane - analogs & derivatives | Islets of Langerhans - enzymology | Glycoproteins - antagonists & inhibitors | Blood Glucose | Treatment Outcome | Insulin - metabolism | Models, Biological | Vildagliptin | Diabetes Mellitus, Type 2 - drug therapy
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10. Full Text Histone Deacetylase Inhibitors Modify Pancreatic Cell Fate Determination and Amplify Endocrine Progenitors
by Cécile Haumaitre and Olivia Lenoir and Raphaël Scharfmann
Molecular and Cellular Biology, ISSN 0270-7306, 10/2008, Volume 28, Issue 20, pp. 6373 - 6383
Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley... 
MORPHOGENESIS | CHROMATIN-STRUCTURE | GENE | BIOCHEMISTRY & MOLECULAR BIOLOGY | BETA-CELLS | TRANSCRIPTION | VALPROIC ACID | GENERATION | ALPHA-CELL | DIFFERENTIATION | TRICHOSTATIN-A | CELL BIOLOGY | Islets of Langerhans - drug effects | Rats, Wistar | Apoptosis - drug effects | Pancreas - cytology | Pancreatic Ducts - drug effects | Stem Cells - cytology | Pancreas, Exocrine - drug effects | Cell Lineage - drug effects | Valproic Acid - pharmacology | Pancreatic Polypeptide-Secreting Cells - cytology | Pancreatic Ducts - enzymology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Pancreas, Exocrine - cytology | Islets of Langerhans - cytology | Female | Hydroxamic Acids - pharmacology | Pancreas - enzymology | Pancreatic Ducts - cytology | Islets of Langerhans - enzymology | Pancreatic Polypeptide-Secreting Cells - enzymology | Enzyme Inhibitors - pharmacology | Pancreas - drug effects | Rats | Pancreatic Polypeptide-Secreting Cells - drug effects | Down-Regulation - drug effects | Pancreas - embryology | Pancreas, Exocrine - enzymology | Nerve Tissue Proteins - metabolism | Animals | Cell Differentiation - drug effects | Stem Cells - drug effects | Cell Proliferation - drug effects | Histone Deacetylase Inhibitors
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11. Full Text Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes
by Silvia Del Guerra and Roberto Lupi and Lorella Marselli and Matilde Masini and Marco Bugliani and Simone Sbrana and Scilla Torri and Maria Pollera and Ugo Boggi and Franco Mosca and Stefano Del Prato and Piero Marchetti
Diabetes, ISSN 0012-1797, 03/2005, Volume 54, Issue 3, pp. 727 - 735
Functional and Molecular Defects of Pancreatic Islets in Human Type 2 Diabetes Silvia Del Guerra , Roberto Lupi , Lorella Marselli , Matilde Masini , Marco... 
PATHOGENESIS | OXIDATIVE STRESS | FREE FATTY-ACIDS | ENDOCRINOLOGY & METABOLISM | COMPLICATIONS | MELLITUS | DYSFUNCTION | INSULIN SECRETORY FUNCTION | GLUCOSE TOXICITY | EXPOSURE | BETA-CELL FUNCTION | Gene Expression | Oxidative Stress | Islets of Langerhans - enzymology | Humans | Middle Aged | Multienzyme Complexes - metabolism | Male | Tyrosine - analogs & derivatives | AMP-Activated Protein Kinases | Glutathione - physiology | Insulin - metabolism | Tyrosine - metabolism | Diabetes Mellitus, Type 2 - physiopathology | Time Factors | Islets of Langerhans - metabolism | Glucose - metabolism | Islets of Langerhans - physiopathology | Adult | Deoxyguanosine - metabolism | Female | Aged | Insulin Secretion | Deoxyguanosine - analogs & derivatives | Protein-Serine-Threonine Kinases - metabolism | Type 2 diabetes | Insulin resistance | Research | Diagnosis | Diabetes | Cardiovascular diseases | Risk factors
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12. Full Text Exendin-4 suppresses Src activation and reactive oxygen species production in diabetic Goto-Kakizaki rat islets in an Epac-dependent manner
by Mukai, Eri and Fujimoto, Shimpei and Sato, Hiroki and Oneyama, Chitose and Kominato, Rieko and Sato, Yuichi and Sasaki, Mayumi and Nishi, Yuichi and Okada, Masato and Inagaki, Nobuya
Diabetes, ISSN 0012-1797, 01/2011, Volume 60, Issue 1, pp. 218 - 226
OBJECTIVE-Reactive oxygen species (ROS) is one of most important factors in impaired metabolism secretion coupling in pancreatic beta-cells. We recently... 
GROWTH-FACTOR RECEPTOR | NADPH OXIDASE | OXIDATIVE STRESS | GLUCAGON-LIKE PEPTIDE-1 | SIGNALING PATHWAY | TYROSINE KINASE | REGULATED EXOCYTOSIS | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | PANCREATIC BETA-CELLS | PROTEIN-COUPLED RECEPTORS | Islets of Langerhans - drug effects | Phosphorylation | Rats, Wistar | Species Specificity | Islets of Langerhans - enzymology | src-Family Kinases - antagonists & inhibitors | Cells, Cultured | Rats | Immunoblotting | Rats, Inbred Strains | Hypoglycemic Agents - pharmacology | Peptides - pharmacology | Reactive Oxygen Species - antagonists & inhibitors | Animals | Adenosine Triphosphate - metabolism | Islets of Langerhans - physiopathology | Venoms - pharmacology | Glucose metabolism | Reactive oxygen species | Peptides | Islands of Langerhans | Research | Properties | Health aspects | Islet Studies
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13. Full Text Co-immobilization of urokinase and thrombomodulin on islet surfaces by poly(ethylene glycol)-conjugated phospholipid
by Chen, Hao and Teramura, Yuji and Iwata, Hiroo
Journal of Controlled Release, ISSN 0168-3659, 03/2011, Volume 150, Issue 2, pp. 229 - 234
Transplantation of islets of Langerhans is a promising method for treating patients with insulin-dependent diabetes mellitus. The major obstacle in clinical... 
Poly(ethylene glycol)–lipid | Urokinase | Surface modification | Thiol | Islet of Langerhans | Maleimide | Thrombomodulin | Poly(ethylene glycol)-lipid | CELLS | ENCAPSULATION | INTRAPORTAL TRANSPLANTATION | PREVENTS | CHEMISTRY, MULTIDISCIPLINARY | INSULIN | ENGRAFTMENT | PHARMACOLOGY & PHARMACY | HUMAN BLOOD | TISSUE FACTOR | LANGERHANS | Enzymes, Immobilized - metabolism | Islets of Langerhans - drug effects | Fluorescein-5-isothiocyanate - metabolism | Polyethylene Glycols - chemistry | Succinimides - chemistry | Sulfhydryl Compounds - metabolism | Thrombomodulin - metabolism | Fluorescein-5-isothiocyanate - chemistry | Islets of Langerhans - metabolism | Mesocricetus | Enzymes, Immobilized - chemical synthesis | Female | Serum Albumin, Bovine - chemistry | Sulfhydryl Compounds - chemistry | Urokinase-Type Plasminogen Activator - chemistry | Cell Membrane - metabolism | Polyethylene Glycols - metabolism | Cricetinae | Islets of Langerhans - enzymology | Fluorescein-5-isothiocyanate - analogs & derivatives | Graft Survival | Glucose - pharmacology | Islets of Langerhans Transplantation - methods | Serum Albumin, Bovine - metabolism | Thrombomodulin - chemistry | Fibrinolysis | Cell Membrane - enzymology | Insulin - metabolism | Animals | Urokinase-Type Plasminogen Activator - metabolism | Enzyme Activation | Phosphatidylethanolamines - metabolism | Protein C - metabolism | Thrombin - metabolism | Maleimides - chemistry | Phosphatidylethanolamines - chemistry | Microscopy, Fluorescence | Glucose metabolism | Ethylene glycol | Phospholipids | Diabetes | Glucose | Dextrose
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14. Full Text The ghrelin gene products and exendin-4 promote survival of human pancreatic islet endothelial cells in hyperglycaemic conditions, through phosphoinositide 3-kinase/Akt, extracellular signal-related kinase (ERK)1/2 and cAMP/protein kinase A (PKA) signalling pathways
by Favaro, E and Granata, R and Miceli, I and Baragli, A and Settanni, F and Cavallo Perin, P and Ghigo, E and Camussi, G and Zanone, M M
Diabetologia, ISSN 0012-186X, 4/2012, Volume 55, Issue 4, pp. 1058 - 1070
Pancreatic islet microendothelium exhibits unique features in interdependent relationship with beta cells. Gastrointestinal products of the ghrelin gene,... 
Hyperglycaemia | Human Physiology | VEGF | Metabolic Diseases | Internal Medicine | Pancreatic islets of Langerhans | Akt | cAMP | Endothelial cells | Exendin-4 | ERK1/2 | Medicine & Public Health | Ghrelin | Obestatin | CAMP. Endothelial cells | APOPTOSIS | FOOD-INTAKE | BETA-CELLS | RECEPTOR | PROLIFERATION | ADHESION | GLUCAGON-LIKE PEPTIDE-1 | GROWTH | ENDOCRINOLOGY & METABOLISM | MICE | EXPRESSION | Phosphorylation - physiology | Islets of Langerhans - drug effects | Apoptosis - drug effects | Humans | Caspase 3 - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Vascular Endothelial Growth Factor A - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | Receptors, Ghrelin - metabolism | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Cyclic AMP - metabolism | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Survival - drug effects | Islets of Langerhans - enzymology | Cells, Cultured | bcl-2-Associated X Protein - metabolism | Receptors, Ghrelin - antagonists & inhibitors | Ghrelin - pharmacology | Glucose - pharmacology | Peptides - pharmacology | Signal Transduction - drug effects | Glucose - metabolism | Cell Proliferation - drug effects | Venoms - pharmacology | Apoptosis - physiology | Endothelial Cells - enzymology | Endothelial Cells - drug effects | ERK1
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15. Full Text L-cysteine inhibits insulin release from the pancreatic β-cell: Possible involvement of metabolic production of hydrogen sulfide, a novel gasotransmitter
by Kaneko, Yukiko and Kimura, Yuka and Kimura, Hideo and