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European Journal of Pharmacology, ISSN 0014-2999, 07/2007, Volume 567, Issue 1-2, pp. 125 - 130
We have shown in past isobolographic studies that a small amount of Δ -tetrahydrocannabinol (Δ -THC) can enhance morphine antinociception in mice. However,... 
Morphine | Arthritis | Synergy | Isobologram | THC
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 10/2013, Volume 170, Issue 3, pp. 679 - 692
Journal Article
by Huang, RY and Pei, LL and Liu, QJ and Chen, SQ and Dou, HB and Shu, G and Yuan, ZX and Lin, JC and Peng, GN and Zhang, W and Fu, HL
FRONTIERS IN PHARMACOLOGY, ISSN 1663-9812, 10/2019, Volume 10
Drug combination is a common method for clinical disease treatment. Whether the combination of drugs is reasonable often affects the result of the disease... 
principle | synergy | COMBINED TOXICITY | LAMBDA-CYHALOTHRIN | COMBINATION | NONLINEAR ISOBOLOGRAM | EARTHWORM EISENIA-FOETIDA | IN-VITRO | application | ANTIBACTERIAL ACTIVITY | drug interaction | PHARMACOLOGY & PHARMACY | BUTACHLOR | isobologram analysis | INDEX | Drug interactions | Analysis | Drug therapy, Combination
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 09/2016, Volume 64, Issue 37, pp. 6939 - 6949
Journal Article
Journal of Molecular Structure, ISSN 0022-2860, 01/2020, Volume 1199, p. 126967
Antioxidant capacity of the phenolic compounds depends on their chemical structures and interactions between them. Twenty binary combinations between four... 
Antioxidant capacity | Flavonoids | Isobologram | Phenolic compounds | Synergism | Interaction | GLYCOSIDES | ACIDS | CHEMISTRY, PHYSICAL | POLYPHENOLS | IRON-CHELATION | DIETARY FIBER | AGLYCONES | CELLULOSE
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 10/2012, Volume 109, Issue 43, pp. E2939 - E2948
Journal Article
Revista Mexicana de Ciencias Farmaceuticas, ISSN 1027-3956, 04/2015, Volume 46, Issue 2, pp. 7 - 16
Journal Article
Synergy, ISSN 2213-7130, 05/2015, Volume 2, Issue 1, pp. 1 - 6
In spite of increasingly improved treatment options breast cancer remains a severe life threatening disease. Major challenges in cancer chemotherapies of today... 
Breast cancer | Synergy | Piperine | Isobologram | Paclitaxel
Journal Article
Frontiers in Pharmacology, ISSN 1663-9812, 07/2016, Volume 7, p. 201
Traditional Chinese medicine (TOM) is an important part of primary health care in Asian countries that has utilized complex herbal formulations (consisting 2... 
Combination index | Chinese herbal medicine | System biology | Synergy | Isobologram | Interaction | GROWTH-INHIBITION | synergy | CANCER CELLS | GINKGO-BILOBA | RADIX | COMBINATION | FORMULA | CHROMATOGRAPHY-MASS-SPECTROMETRY | system biology | SALVIA-MILTIORRHIZA | ATHEROGENIC EVENTS | POLYPHYLLIN I | interaction | PHARMACOLOGY & PHARMACY | isobologram | combination index | Patient outcomes | Medicine, Chinese
Journal Article
Journal of Oral and Facial Pain and Headache, ISSN 2333-0384, 2018, Volume 32, Issue 3, pp. 247 - 257
To evaluate in mice the antinociceptive effect of copper in spinal and trigeminal nociceptive pathways by using the intraplantar and orofacial formalin tests,... 
Isobologram | Ketamine | Intraplantar formalin | Copper | Orofacial formalin
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 03/2019, Volume 846, pp. 73 - 78
The aim of the study was to investigate the analgesic effects of adding serotonin to oxybuprocaine or proxymetacaine preparations. We employed a rat model of... 
Infiltrative cutaneous analgesia | Coadministration | Proxymetacaine | Isobologram | Serotonin | Oxybuprocaine | INCREASES | REGIONAL ANESTHESIA | BUPIVACAINE | PAIN | LIDOCAINE | PHARMACOLOGY & PHARMACY | NOCICEPTIVE BLOCK | INGUINAL HERNIORRHAPHY | EPINEPHRINE | VASOCONSTRICTION | DURATION | Analgesia | Medical colleges | Analgesics | Phenols | Rankings | Skin
Journal Article
PHARMACOLOGICAL REPORTS, ISSN 1734-1140, 08/2019, Volume 71, Issue 4, pp. 732 - 737
Background: Dextrorphan with long-acting local anesthetic effects did not cause system toxicity as fast as bupivacaine, while catecholamines (i.e.,... 
Dopamine | PROXYMETACAINE | BUPIVACAINE | Skin antinociception | ISOBOLOGRAPHIC ANALYSIS | WOUND INFILTRATION | ANESTHESIA | DEXTROMETHORPHAN | Isobologram | CUTANEOUS ANALGESIA | PHARMACOLOGY & PHARMACY | Pinpricks | OXYBUPROCAINE | Dextrorphan | NOCICEPTIVE BLOCK | EPINEPHRINE
Journal Article
BRAIN RESEARCH, ISSN 0006-8993, 01/2018, Volume 1678, pp. 164 - 173
To investigate the interaction between hippocampal gamma-aminobutyric acid GABA(A) receptor (GABA(A)R) or GABA(B) receptor (GABA(B)R) and N-methyl-D-aspartate... 
Rat | ISOBOLOGRAM ANALYSIS | D-ASPARTATE RECEPTORS | MEMORY RETENTION | NEUROSCIENCES | D-AP5 | Passive avoidance memory | GAMMA-AMINOBUTYRIC ACID(A) | GABA(B) receptor | DORSAL HIPPOCAMPUS | GABA(A) receptor | POSITIVE MODULATOR BHF177 | INDUCED AMNESIA | RAT HIPPOCAMPUS | INDUCED PLACE PREFERENCE | LONG-TERM POTENTIATION
Journal Article
Food and Chemical Toxicology, ISSN 0278-6915, 10/2018, Volume 120, pp. 12 - 23
Patulin (PAT), deoxynivalenol (DON) and toxin T-2 (T-2) are mycotoxins distributed worldwide in food and feed. Cytotoxicity of the three mycotoxins... 
Cytotoxicity | HepG2 cells | Isobologram | Interactions | Mycotoxins | OXIDATIVE STRESS | INDUCED APOPTOSIS | FOOD SCIENCE & TECHNOLOGY | ENNIATIN B | BEAUVERICIN | TOXICITY | FUMONISIN B-1 | TOXICOLOGICAL INTERACTIONS | MYCOTOXINS DEOXYNIVALENOL | FUSARIUM MYCOTOXINS | TOXICOLOGY | ZEARALENONE | Drugstores | Pharmacy
Journal Article
Drug Development Research, ISSN 0272-4391, 11/2018, Volume 79, Issue 7, pp. 362 - 369
Journal Article