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Cell (Cambridge), ISSN 0092-8674, 06/2016, Volume 165, Issue 7, pp. 1698 - 1707
Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Sulfonamides - chemistry | Humans | Models, Molecular | Crystallography, X-Ray | Glutamate Dehydrogenase - chemistry | Isocitrate Dehydrogenase - antagonists & inhibitors | Sulfonamides - pharmacology | Drug Discovery | Isocitrate Dehydrogenase - ultrastructure | Cryoelectron Microscopy | Glutamate Dehydrogenase - ultrastructure | L-Lactate Dehydrogenase - chemistry | Animals | L-Lactate Dehydrogenase - ultrastructure | Cattle | Isocitrate Dehydrogenase - chemistry | Aminoquinolines - chemistry | Chickens | Glutamate Dehydrogenase - antagonists & inhibitors | Protein Conformation | L-Lactate Dehydrogenase - antagonists & inhibitors | Aminoquinolines - pharmacology | Proteins | Analysis | Physiological aspects | Atoms | Drug discovery | Glutamate | Cells | Enzymes | Protein binding | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 04/2012, Volume 287, Issue 17, pp. 14078 - 14086
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Sirtuin 3 - metabolism | Oxidation-Reduction | Oxidative Stress | Caloric Restriction | Humans | Gene Expression Regulation | Mitochondria - metabolism | NADP - chemistry | Animals | Sirtuins - chemistry | Models, Biological | HEK293 Cells | Isocitrate Dehydrogenase - metabolism | Fibroblasts - cytology | Glutathione - chemistry | Mice | Lysine - chemistry | Index Medicus | Sirtuins | Deacetylation | Metabolic Regulation | Redox Regulation | Metabolism | Isocitrate Dehydrogenase | Histone Deacetylase | Mitochondrial Metabolism
Journal Article
The FASEB journal, ISSN 0892-6638, 06/2015, Volume 29, Issue 6, pp. 2462 - 2472
adaptation | phylogenetic analysis | kinetics | coenzyme specificity determinants | Phylogenetic analysis | Kinetics | Coenzyme specificity determinants | Adaptation | Biochemistry & Molecular Biology | Biology | Life Sciences & Biomedicine - Other Topics | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Molecular Weight | Protein Multimerization | Molecular Sequence Data | Substrate Specificity | Phylogeny | NADP - chemistry | NAD - chemistry | Chlorophyta - genetics | Isocitrate Dehydrogenase - classification | Base Sequence | Algal Proteins - genetics | Molecular Structure | NADP - metabolism | Circular Dichroism | NAD - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Algal Proteins - chemistry | Isocitrates - metabolism | Models, Molecular | Magnesium - metabolism | Binding Sites - genetics | Blotting, Western | Sequence Homology, Amino Acid | Manganese - metabolism | Chlorophyta - enzymology | Isocitrate Dehydrogenase - chemistry | Protein Binding | Isocitrate Dehydrogenase - metabolism | Mutation | Algal Proteins - metabolism | Index Medicus
Journal Article
The Journal of biological chemistry, ISSN 0021-9258, 09/2015, Volume 290, Issue 2, pp. 762 - 774
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Isocitrate Dehydrogenase - biosynthesis | Escherichia coli | Humans | Gene Expression Regulation, Neoplastic | Mutant Proteins - genetics | Crystallography, X-Ray | Isocitrate Dehydrogenase - genetics | DNA Methylation - genetics | Enzyme Inhibitors - chemical synthesis | Isocitrate Dehydrogenase - antagonists & inhibitors | Drug Discovery | Enzyme Inhibitors - therapeutic use | Neoplasms - drug therapy | Magnesium - chemistry | Neoplasms - genetics | Isocitrate Dehydrogenase - chemistry | Enzyme Inhibitors - chemistry | Mutant Proteins - chemistry | Allosteric Site | Protein Conformation | Neoplasms - pathology | Index Medicus | Mechanism of Inhibition | Cancer Metabolism | Drug Action | IDH1 Inhibitor | Enzymology | Metalloenzyme | Anticancer Drug | Enzyme Inhibitor
Journal Article
Science (American Association for the Advancement of Science), ISSN 0036-8075, 5/2013, Volume 340, Issue 6132, pp. 622 - 626
Molecules | Enzymes | Dehydrogenases | Blasts | Myeloid leukemia | REPORTS | Stem cells | Bone marrow cells | Cellular differentiation | Hematopoietic stem cells | Mesenchymal stem cells | Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Cell Proliferation | Humans | Protein Multimerization | Crystallography, X-Ray | Erythropoiesis - drug effects | Isocitrate Dehydrogenase - antagonists & inhibitors | Molecular Targeted Therapy | Hematopoiesis - drug effects | Antineoplastic Agents - metabolism | Leukemia, Myeloid, Acute - enzymology | Phenylurea Compounds - chemistry | Enzyme Inhibitors - chemistry | Leukemia, Myeloid, Acute - drug therapy | Antineoplastic Agents - pharmacology | Phenylurea Compounds - metabolism | Mutant Proteins - antagonists & inhibitors | Catalytic Domain | Enzyme Inhibitors - metabolism | Protein Structure, Secondary | Sulfonamides - chemistry | Leukemia, Myeloid, Acute - pathology | Cells, Cultured | Enzyme Inhibitors - pharmacology | Isocitrate Dehydrogenase - genetics | Mutant Proteins - metabolism | Gene Expression Regulation, Leukemic | Antineoplastic Agents - chemistry | Sulfonamides - pharmacology | Point Mutation | Isocitrate Dehydrogenase - chemistry | Small Molecule Libraries | Mutant Proteins - chemistry | Allosteric Site | Sulfonamides - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - metabolism | Phenylurea Compounds - pharmacology | Leukemia, Erythroblastic, Acute | Leukemia, Myeloid, Acute - genetics | Leukemia | Cancer cells | Physiological aspects | Research | Oxidoreductases | Cell differentiation | Health aspects | Mutation | Cellular biology | Drug therapy | Cells | Index Medicus
Journal Article
Biochimica et biophysica acta. Bioenergetics, ISSN 0005-2728, 2009, Volume 1787, Issue 11, pp. 1309 - 1316
ATP supply | Mitochondria | Calcium binding | Calcium ion | Dehydrogenase | Vertebrate | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Mitochondria - enzymology | Animals | Calcium - physiology | Pyruvate Dehydrogenase (Lipoamide)-Phosphatase - physiology | Humans | Enzyme Activation | Glycerolphosphate Dehydrogenase - physiology | Ketoglutarate Dehydrogenase Complex - physiology | Isocitrate Dehydrogenase - physiology | Phosphates | Cell research | Mitochondrial DNA | Oxidoreductases | Laws, regulations and rules
Journal Article
Biochemical journal, ISSN 0264-6021, 01/2017, Volume 474, Issue 1, pp. 105 - 122
Life Sciences & Biomedicine | Biochemistry & Molecular Biology | Science & Technology | Thermococcus - genetics | Archaeal Proteins - chemistry | Substrate Specificity | Structure-Activity Relationship | Genetic Complementation Test | Oxidoreductases - chemistry | Thermus thermophilus - genetics | Isocitrates - chemistry | Thermococcus - enzymology | Malates - metabolism | Archaeal Proteins - genetics | Archaeal Proteins - metabolism | Recombinant Proteins - metabolism | Thermus thermophilus - enzymology | Catalytic Domain | Oxidoreductases - metabolism | Protein Structure, Secondary | Oxidoreductases - genetics | Isocitrates - metabolism | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Tricarboxylic Acids - metabolism | Lysine - genetics | Malates - chemistry | Lysine - biosynthesis | Lysine - chemistry | Tricarboxylic Acids - chemistry | Index Medicus
Journal Article
Marine chemistry, ISSN 0304-4203, 08/2018, Volume 204, pp. 86 - 94
Journal Article
Current opinion in neurology, ISSN 1350-7540, 12/2011, Volume 24, Issue 6, pp. 648 - 652
somatic mutation | glioma | isocitrate dehydrogenase | Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Biomarkers - metabolism | Brain Neoplasms - enzymology | Glioma - enzymology | Prognosis | Glioma - diagnosis | Isoenzymes - genetics | Brain Neoplasms - diagnosis | Humans | Isocitrates - metabolism | Brain Neoplasms - genetics | Isocitrate Dehydrogenase - genetics | Isoenzymes - chemistry | Glioma - genetics | Point Mutation | Isocitrate Dehydrogenase - chemistry | Isoenzymes - metabolism | Isocitrate Dehydrogenase - metabolism | Protein Conformation | Ketoglutaric Acids - metabolism | Index Medicus | Isocitrate dehydrogenase
Journal Article