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CELL DEATH & DISEASE, ISSN 2041-4889, 04/2018, Volume 9, Issue 5, pp. 488 - 13
Mitochondrial NADP(+)-dependent isocitrate dehydrogenase (IDH2) plays an important role in the formation of NADPH, which is critical for the maintenance of... 
OXYGEN | METABOLISM | INDUCED APOPTOSIS | RAT-KIDNEY | GLUTATHIONE | ANTIOXIDANT | INJURY | INDUCED NEPHROTOXICITY | STRESS | BCL-2 FAMILY-MEMBERS | CELL BIOLOGY | Oxidative stress | Dehydrogenases | Kidneys | Hydrogen peroxide | DNA damage | IDH2 gene | Mitochondrial DNA | Cisplatin | Antioxidants | Cell death | NADP | Isocitrate dehydrogenase | Deoxyribonucleic acid--DNA | Apoptosis
Journal Article
Journal of Molecular Medicine, ISSN 0946-2716, 3/2019, Volume 97, Issue 3, pp. 385 - 396
Journal Article
Nature, ISSN 0028-0836, 01/2012, Volume 481, Issue 7381, pp. 380 - 384
Acetyl coenzyme A (AcCoA) is the central biosynthetic precursor for fatty-acid synthesis and protein acetylation. In the conventional view of mammalian cell... 
FLUX ANALYSIS | DISTRIBUTIONS | FATTY-ACID SYNTHESIS | MULTIDISCIPLINARY SCIENCES | GROWTH | HYDROXYLATION | CELL-PROLIFERATION | SUPPRESSION | HIF-ALPHA | CANCER | DEHYDROGENASE | CD8-Positive T-Lymphocytes - cytology | Palmitic Acid - metabolism | Isocitrate Dehydrogenase - deficiency | Humans | Glutamine - metabolism | Kidney Neoplasms - metabolism | Aryl Hydrocarbon Receptor Nuclear Translocator - metabolism | Oxygen - metabolism | Cell Hypoxia | Basic Helix-Loop-Helix Transcription Factors - metabolism | Acetyl Coenzyme A - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Von Hippel-Lindau Tumor Suppressor Protein - genetics | Ketoglutaric Acids - metabolism | Lipogenesis | Von Hippel-Lindau Tumor Suppressor Protein - metabolism | Carbon - metabolism | Basic Helix-Loop-Helix Transcription Factors - genetics | Oxidation-Reduction | Carcinoma, Renal Cell - pathology | Cells, Cultured | Isocitrate Dehydrogenase - genetics | Acetyl Coenzyme A - metabolism | Citric Acid Cycle | Carcinoma, Renal Cell - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Kidney Neoplasms - pathology | Physiological aspects | Hypoxia | Research | Lipid metabolism | Electron transport | Proteins | Confidence intervals | Metabolites | Lipids | Biosynthesis | Glucose | Experiments | Index Medicus
Journal Article
Journal of Neuroscience, ISSN 0270-6474, 06/2017, Volume 37, Issue 23, pp. 5770 - 5781
Journal Article
Nature, ISSN 0028-0836, 04/2016, Volume 532, Issue 7598, pp. 255 - 258
Journal Article
Journal Article
Journal Article
Acta Neuropathologica, ISSN 0001-6322, 12/2010, Volume 120, Issue 6, pp. 719 - 729
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 10/2016, Volume 99, pp. 179 - 188
Reactive oxygen species (ROS) are a byproduct of normal metabolism and play important roles in cell signaling and homeostasis. Mitochondria, the main... 
Obesity | Isocitrate dehydrogenase 2 | Reactive oxygen species | ACTIVATION | MAP KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | SYSTEMIC OXIDATIVE STRESS | P53 | DIABETES-MELLITUS | GLUTATHIONE | ENDOCRINOLOGY & METABOLISM | FAT DEVELOPMENT | EXPRESSION | BROWN | ADIPOCYTE | Thermogenesis - genetics | Isocitrate Dehydrogenase - deficiency | Reactive Oxygen Species - metabolism | Oxidative Stress | Diabetes Mellitus, Type 2 - genetics | Adipocytes - cytology | Intra-Abdominal Fat - cytology | Diabetes Mellitus, Type 2 - metabolism | Obesity - genetics | p38 Mitogen-Activated Protein Kinases - metabolism | Energy Metabolism - genetics | Sterol Regulatory Element Binding Protein 1 - metabolism | Uncoupling Protein 1 - genetics | Oxidation-Reduction | Signal Transduction | Uncoupling Protein 1 - metabolism | Mice, Inbred C57BL | Diabetes Mellitus, Type 2 - prevention & control | Gene Expression Regulation | p38 Mitogen-Activated Protein Kinases - genetics | Isocitrate Dehydrogenase - genetics | Mitochondria - metabolism | Intra-Abdominal Fat - metabolism | Mice, Knockout | Obesity - metabolism | Obesity - pathology | Insulin - metabolism | Animals | Sterol Regulatory Element Binding Protein 1 - genetics | Adipocytes - metabolism | Obesity - prevention & control | Insulin Resistance - genetics | Mice | Diabetes Mellitus, Type 2 - pathology | Type 2 diabetes | Physiological aspects | Medical colleges | Index Medicus
Journal Article