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Angewandte Chemie International Edition, ISSN 1433-7851, 02/2019, Volume 58, Issue 7, pp. 1849 - 1849
Dual gold activation is an important catalytic mode in homogeneous catalysis. In their Communication on page 2114 ff., S. G. Pyne, C. J. T. Hyland, and... 
cycloaromatization | isoindolinones | dual-gold catalysis | enediynes
Journal Article
Angewandte Chemie, ISSN 0044-8249, 11/2017, Volume 129, Issue 48, pp. 15648 - 15653
Elektrochemie im Fluss ist eine effiziente Methode zur Erzeugung radikalischer Zwischenstufen. Ein elektrochemischer Flussmikroreaktor wurde entwickelt, um die... 
Isoindolinone | Flusselektrochemie | Cyclisierungen | Mikroreaktoren | Tandemreaktionen
Journal Article
Synlett, ISSN 0936-5214, 05/2017, Volume 28, Issue 8, pp. 889 - 897
Journal Article
Angewandte Chemie International Edition, ISSN 1433-7851, 11/2017, Volume 56, Issue 48, pp. 15353 - 15357
The catalytic enantioselective synthesis of isoindolinones was achieved through the condensation of 2‐acyl‐benzaldehydes and anilines. In the presence of 1 mol... 
mariline A | asymmetric catalysis | Brønsted acid catalysis | isoindolinones | atropisomerism | mariline A | Phosphates | Phosphoric acid | Catalysis | Enantiomers
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 02/2019, Volume 361, Issue 3, pp. 456 - 461
The first p‐TSA‐catalyzed highly diastereoselective Michael addition/cyclization of 3‐carboxylate‐substituted isoindolinones and ortho‐hydroxychalcones was... 
Michael addition | bridged ring | polycyclic isoindolinone | diastereoselective | cyclization | PHTHALIMIDES | ARYLATIVE DEAROMATIZATION | CHEMISTRY, ORGANIC | INDOLE | CONSTRUCTION | KETAL SPIROOXINDOLES | CHEMISTRY, APPLIED | DERIVATIVES | ACCESS | Stereoselectivity | Bridge construction
Journal Article
Tetrahedron, ISSN 0040-4020, 06/2015, Volume 71, Issue 22, pp. 3632 - 3636
A convenient and efficient copper-catalyzed aerobic cascade reaction has been developed for the synthesis of the pharmacologically relevant... 
Isoindolinone | Aerobic | Dehydrgenation | Copper | Cascade | ANNULATION | CHEMISTRY, ORGANIC | ALDEHYDES | STEREOSELECTIVE-SYNTHESIS | Dehydrogenation
Journal Article
Organic Letters, ISSN 1523-7060, 11/2017, Volume 19, Issue 21, pp. 5884 - 5887
The oxidative cyclization of substituted benzamides with maleimides assisted by 8-aminoquinoline in the presence of a catalytic amount of Co­(OAc)2·4H2O... 
ISOINDOLINONES | DIRECTED FUNCTIONALIZATION | AROMATIC AMIDES | CHEMISTRY, ORGANIC | ARYL | STEREOSELECTIVE-SYNTHESIS | 1,4-ADDITION | BOND | C-H ACTIVATION | DERIVATIVES | CARBON-HYDROGEN
Journal Article
Beilstein Journal of Organic Chemistry, ISSN 1860-5397, 10/2013, Volume 9, Issue 1, pp. 2048 - 2078
This review highlights the chemical and biological aspects of natural products containing an oxidized or reduced isoindole skeleton. This motif is found in its... 
Isoindolinone | Isoindolone | Isoindoline | Natural products | Isoindole | isoindolinone | MARINE STREPTOMYCES SP | BETA-PHENYLETHYLAMINES | ISOQUINOLINE ALKALOIDS | CHEMISTRY, ORGANIC | STACHYBOTRYS SP | ARISTOLOCHIC ACID | ARISTOCULARINE ALKALOIDS | natural products | BIOSYNTHETIC GENE-CLUSTER | DIELS-ALDER REACTION | isoindole | isoindoline | HIV-1 PROTEASE | isoindolone | CYTOCHALASIN-D
Journal Article
Synlett, ISSN 0936-5214, 03/2013, Volume 24, Issue 5, pp. 645 - 651
Abstract We have reported a microwave-assisted, ligand-free Pd-catalyzed domino C–C/C–N coupling reaction to construct diverse isoindolinone derivatives using... 
letter | isoindolinone | amides | isocyanides | ligand | Pd-catalyzed | ASYMMETRIC-SYNTHESIS | ONE-POT SYNTHESIS | CHEMISTRY, ORGANIC | INTERNAL ALKYNES | H ACTIVATION | CARBONYLATION | ISOCYANIDE | PRIMARY AMINES | ARYL | 3-SUBSTITUTED ISOINDOLINONES | CYCLIZATION
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 04/2019, Volume 168, pp. 110 - 122
Histone deacetylases (HDACs) as appealing targets for the treatment of many diseases has been studied extensively and its use in cancer care is the most... 
Antiproliferation | Isoindolinone | HDAC inhibitor | Synthesis | Structural optimization | CONFORMATIONAL RESTRICTION | CHEMISTRY, MEDICINAL | T-CELL LYMPHOMA | CANCER | CHIDAMIDE CS055/HBI-8000 | IN-VITRO | STEREOSELECTIVE-SYNTHESIS | EXPRESSION | HDAC | Medical research | Pharmacy | Analysis | Liver | Physiological aspects | Medicine, Experimental | Drugstores | Drug approval | Index Medicus
Journal Article
Organic Letters, ISSN 1523-7060, 07/2015, Volume 17, Issue 13, pp. 3302 - 3305
Silver-catalyzed interrupted Feist-Benary reaction is described for the efficient enantioselective synthesis of dihydrofuran heterocycles. A new method has... 
ISOINDOLINONES | ROUTE | 1,3-DICARBONYL COMPOUNDS | SILVER | CHEMISTRY, ORGANIC | DERIVATIVES | EFFICIENT | CYCLIZATION | ACCESS | CONJUGATE ADDITION | DIHYDROFURANS
Journal Article
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 06/2018, Volume 140, Issue 23, pp. 7292 - 7300
Given the growing demand for green and sustainable chemical processes, the catalytic reductive alkylation of amines with main-group catalysts of low toxicity... 
ISOINDOLINONES | AMINATION | ACTIVATION | HYDROGENATION | B(C6F5) | CHEMISTRY | N-ALKYLATION | FRUSTRATED LEWIS PAIRS | CHEMISTRY, MULTIDISCIPLINARY | METAL-FREE
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 1900, Volume 137, Issue 18, pp. 5907 - 5910
Journal Article
by Zhou, X and Xu, HY and Yang, QD and Chen, H and Wang, SF and Zhao, HQ
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 07/2019, Volume 55, Issue 59, pp. 8603 - 8606
A cobalt and copper catalyzed reaction protocol has been developed to achieve the oxidative C-H/N-H annulation of benzamides containing an 8-aminoquinoline... 
ISOINDOLINONES | DEHYDROGENATION | CARBONYLATION | OLEFINATION | BOND FUNCTIONALIZATIONS | PROPARGYL ALCOHOLS | FORM GAMMA-LACTAMS | SATURATED KETONES | EFFICIENT | CHEMISTRY, MULTIDISCIPLINARY | DIRECT BETA-ARYLATION
Journal Article
Organic Letters, ISSN 1523-7060, 03/2016, Volume 18, Issue 5, pp. 1146 - 1149
Aryl-aldehydes containing ortho-substituted propiolate fragments react with hydroxylamine to afford carbinolamine intermediates that undergo intramolecular... 
ISOINDOLINONES | ANTAGONIST | HYDROXAMIC ACIDS | REDUCTION | GAMMA-BUTYROLACTONE | ANALOGS | ENANTIOMERS | EFFICIENT SYNTHESIS | CHEMISTRY, ORGANIC | INHIBITORS | DERIVATIVES
Journal Article