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by J Chen and M Liu and Z Zhou and J Ke and S Huang and D Huang and W Wu
Heart, ISSN 1355-6037, 01/2015, Volume 101, Issue 2, p. A24
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 10/2015, Volume 764, pp. 283 - 291
The present study was carried out to evaluate the protective effect of different statins on isoproterenol (ISO) induced myocardial necrosis. Atorvastatin,... 
Fluvastatin | Simvastatin | Atorvastatin | Rosuvastatin | Myocardial necrosis | Isoproterenol | Pravastatin | CHRONIC HEART-FAILURE | COENZYME-A REDUCTASE | CHOLESTEROL | INFARCTION | PLASMA | PHARMACOLOGY & PHARMACY | RAT-HEART | LIPOPROTEINS | STATIN TREATMENT | Necrosis - drug therapy | Myocardial Infarction - chemically induced | Simvastatin - therapeutic use | Fatty Acids, Monounsaturated - pharmacology | Rosuvastatin Calcium - therapeutic use | Rats, Wistar | Atorvastatin Calcium - pharmacology | Glutathione - metabolism | Cholesterol - blood | Male | Simvastatin - pharmacology | Necrosis - pathology | Cardiotonic Agents - therapeutic use | Fatty Acids, Monounsaturated - therapeutic use | Myocardial Infarction - pathology | Myocardium - metabolism | Indoles - pharmacology | Pravastatin - therapeutic use | Atorvastatin Calcium - therapeutic use | Superoxide Dismutase - metabolism | Pravastatin - pharmacology | Blood Glucose - analysis | Rosuvastatin Calcium - pharmacology | Adenosine Triphosphatases - metabolism | Myocardium - pathology | Necrosis - metabolism | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Necrosis - chemically induced | Catalase - metabolism | Animals | Hydroxymethylglutaryl-CoA Reductase Inhibitors - pharmacology | Myocardial Infarction - drug therapy | Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use | Isoproterenol - pharmacology | Triglycerides - blood | Indoles - therapeutic use | Isoproterenol - therapeutic use | Antioxidants | Pharmacy | Drugstores | Glucose | Comparative analysis | Statins | Dextrose | Necrosis
Journal Article
Respirology, ISSN 1323-7799, 08/2017, Volume 22, Issue 6, pp. 1084 - 1092
ABSTRACT Inhaled mucoactive agents are used in respiratory disease to improve mucus properties and enhance secretion clearance. The effect of mannitol,... 
expectorants | lung diseases | sputum | respiratory function tests | humans | ISOTONIC SALINE | DRY POWDER MANNITOL | CLEARANCE | SAFETY | ACETYLCYSTEINE-ISOPROTERENOL | INHALATION | BRONCHIECTASIS | SALINE-ISOPROTERENOL | OBSTRUCTIVE PULMONARY-DISEASE | RESPIRATORY SYSTEM | TERBUTALINE | Recombinant Proteins - therapeutic use | Humans | Deoxyribonuclease I - therapeutic use | Mesna - therapeutic use | Lung Diseases - drug therapy | Mannitol - pharmacology | Mucociliary Clearance - drug effects | Symptom Flare Up | Forced Expiratory Volume | Expectorants - therapeutic use | Deoxyribonuclease I - pharmacology | Saline Solution, Hypertonic - therapeutic use | Acetylcysteine - therapeutic use | Bronchiectasis - drug therapy | Mannitol - therapeutic use | Administration, Inhalation | Saline Solution, Hypertonic - pharmacology | Recombinant Proteins - pharmacology | Vital Capacity | Acetylcysteine - pharmacology | Quality of Life | Expectorants - pharmacology | Lung Diseases - physiopathology | Bronchiectasis - physiopathology | Chronic Disease | Cystic fibrosis | Respiratory agents | Pulmonary function tests | Drug therapy | Analysis | Deoxyribonuclease | Secretion | Lung diseases | Acetylcysteine | Mucus | Bronchiectasis | Cough | Asthma | Quality of life | Bronchospasm | Side effects | Respiratory diseases | Sputum | Mannitol | Chronic obstructive pulmonary disease
Journal Article
Journal of Emergency Medicine, ISSN 0736-4679, 2016, Volume 52, Issue 4, pp. e123 - e127
Abstract Background Oral tyrosine kinase inhibitors (TKIs) are becoming increasingly common in oncology practice due to ease of administration and patient... 
Emergency | ibrutinib | dysrhythmia | tyrosine kinase inhibitor | ventricular storm | torsades des pointes | electrical storm | THERAPY | EMERGENCY MEDICINE | Lidocaine - pharmacology | Pyrazoles - therapeutic use | Respiration, Artificial - methods | Anti-Arrhythmia Agents - pharmacology | Humans | Middle Aged | Lidocaine - therapeutic use | Male | Antineoplastic Agents - therapeutic use | Cardiotonic Agents - therapeutic use | Waldenstrom Macroglobulinemia - drug therapy | Amiodarone - therapeutic use | Antineoplastic Agents - adverse effects | Emergency Service, Hospital - organization & administration | Antineoplastic Agents - pharmacology | Torsades de Pointes - diagnosis | Torsades de Pointes - drug therapy | Electrocardiography - methods | Extracorporeal Membrane Oxygenation - methods | Amiodarone - pharmacology | Electric Countershock - methods | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Tachycardia, Ventricular - therapy | Intra-Aortic Balloon Pumping - methods | Tachycardia, Ventricular - etiology | Anti-Arrhythmia Agents - therapeutic use | Cardiotonic Agents - pharmacology | Intensive Care Units - organization & administration | Pyrimidines - pharmacology | Magnesium - pharmacology | Electrophysiology - manpower | Magnesium - therapeutic use | Electrophysiology - methods | Pyrimidines - therapeutic use | Isoproterenol - pharmacology | Tachycardia, Ventricular - diagnosis | Pyrimidines - adverse effects | Syncope - etiology | Isoproterenol - therapeutic use | Tyrosine | Phenols | Tachycardia | Emergency medicine | Ventricular tachycardia | Risk factors
Journal Article
PLoS ONE, ISSN 1932-6203, 12/2016, Volume 11, Issue 12, pp. e0167768 - e0167768
Delonix regia (Boj. Ex. Hook) is a flowering plant in the pea family found in tropical areas and its leaves are used informally to treat diseases in folk... 
AORTIC ENDOTHELIAL-CELLS | TUMOR-NECROSIS-FACTOR | ANTIINFLAMMATORY ACTIVITY | DOWN-REGULATES ENOS | NITRIC-OXIDE SYNTHASE | PHENOLIC-COMPOUNDS | MULTIDISCIPLINARY SCIENCES | ISOPROTERENOL INFUSION | HEART-FAILURE | FLAVONOIDS | FACTOR-ALPHA | Heart Injuries - pathology | Plant Extracts - chemistry | Vasodilator Agents - therapeutic use | Tumor Necrosis Factor-alpha - blood | Cardiomegaly - pathology | Isoproterenol | Heart Injuries - drug therapy | Cardiotonic Agents - therapeutic use | Heart Injuries - blood | Swine | Female | Plant Leaves - chemistry | Nitric Oxide - blood | Creatine Kinase - blood | Cardiomegaly - blood | Fabaceae - chemistry | Mice, Inbred C57BL | Cardiomegaly - drug therapy | Vasodilator Agents - isolation & purification | Plant Extracts - isolation & purification | Cardiotonic Agents - chemistry | Animals | Cardiotonic Agents - isolation & purification | Cardiomegaly - chemically induced | Heart - drug effects | Heart Injuries - chemically induced | Vasodilator Agents - chemistry | Mice | Plant Extracts - therapeutic use | Legumes | Care and treatment | Beans | Tumor necrosis factor | Heart enlargement | Analysis | Medicine, Botanic | Medicine, Herbal | Research | Health aspects | Mimosaceae | Heart | Creatine kinase | Creatine | Experiments | Foreign students | Vasodilation | Antioxidants | Leaves | Atherosclerosis | Toxicity testing | Flowering | Food | Medicinal plants | Metabolic wastes | Research & development--R&D | Coronary artery | Antimicrobial agents | Pharmacology | Tumor necrosis factor-α | Chemical compounds | Medicine | Serum levels | Herbal medicine | Plant diseases | Flavonoids | Injury prevention | Hospitals | Acids | Nitric oxide | Pharmacy | Overdose | Laboratory animals | Hypertrophy | Index Medicus | Research & development | R&D
Journal Article
European Journal of Pharmacology, ISSN 0014-2999, 2009, Volume 615, Issue 1, pp. 125 - 132
The present study was designed to evaluate the cardioprotective potential of salvianolic acid A on isoproterenol-induced myocardial infarction in rats.... 
Myocardial infarction | Hemodynamic parameters | Isoproterenol | Salvianolic acid A | Antioxidant | Mitochondrial respiratory function | WISTAR RATS | LIPID-PEROXIDATION | MEMBRANE-PERMEABILITY | MITOCHONDRIA | NARINGIN | INDUCED CARDIOTOXICITY | NECROSIS | LIVER-INJURY | PHARMACOLOGY & PHARMACY | HYDROGEN-PEROXIDE | RABBIT HEART | L-Lactate Dehydrogenase - metabolism | Myocardial Infarction - chemically induced | Mitochondria, Heart - metabolism | Mitochondria, Heart - pathology | Plant Extracts - pharmacology | Caffeic Acids - pharmacology | Male | Cardiotonic Agents - therapeutic use | Myocardium - metabolism | Electrocardiography | Caffeic Acids - therapeutic use | Myocardial Infarction - physiopathology | Phytotherapy | Superoxide Dismutase - metabolism | Biomarkers - metabolism | Lactates - pharmacology | Malondialdehyde - metabolism | Glutathione Peroxidase - metabolism | Creatine Kinase - blood | Rats | Lactates - therapeutic use | Myocardium - pathology | Antioxidants - pharmacology | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Aspartate Aminotransferases - metabolism | Catalase - metabolism | Antioxidants - therapeutic use | Animals | Aspartate Aminotransferases - blood | L-Lactate Dehydrogenase - blood | Creatine Kinase - metabolism | Hemodynamics - drug effects | Myocardial Infarction - prevention & control | Oxidative Stress - drug effects | Plant Extracts - therapeutic use | Antioxidants | Creatine kinase | Superoxide dismutase | Lactate dehydrogenase | Aspartate | Superoxide | Creatine | Heart attack | Glutathione | Index Medicus
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 08/2017, Volume 377, Issue 6, pp. 594 - 595
Data from 47 hospitals show sharp decreases in the use of nitroprusside and isoproterenol after large increases in price. These findings refute public... 
MEDICINE, GENERAL & INTERNAL | Nitroprusside - economics | Drug Utilization - economics | Hospitals | United States | Humans | Isoproterenol - therapeutic use | Drug Utilization - statistics & numerical data | Isoproterenol - economics | Nitroprusside - therapeutic use
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2016, Volume 11, Issue 10, p. e0164795
Introduction Human induced pluripotent stem cells (hiPSCs) offer a unique opportunity for disease modeling. However, it is not invariably successful to... 
RATE DEPENDENCE | CALCIUM-RELEASE CHANNELS | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | SUDDEN CARDIAC DEATH | MUSCLE | CHANNEL RYANODINE RECEPTOR | CARDIOMYOCYTES | MUTATIONS | FAILING HEARTS | FKBP12.6 | Electric Stimulation | Anti-Asthmatic Agents - therapeutic use | Calcium - metabolism | Humans | Ryanodine Receptor Calcium Release Channel - metabolism | Transplantation, Heterologous | Calsequestrin - genetics | Thiazepines - therapeutic use | Calreticulin - genetics | Thiazepines - chemistry | Calreticulin - metabolism | Adult | Induced Pluripotent Stem Cells - cytology | Calsequestrin - metabolism | Action Potentials - drug effects | Ryanodine - pharmacology | Anti-Asthmatic Agents - chemistry | Fibroblasts - metabolism | Induced Pluripotent Stem Cells - metabolism | Tachycardia, Ventricular - therapy | Anti-Asthmatic Agents - pharmacology | Sarcoplasmic Reticulum Calcium-Transporting ATPases - metabolism | Myocytes, Cardiac - cytology | Tachycardia, Ventricular - drug therapy | Cells, Cultured | Thiazepines - pharmacology | Mice, SCID | Myocytes, Cardiac - transplantation | Animals | Myocytes, Cardiac - drug effects | Ryanodine Receptor Calcium Release Channel - genetics | Cell Differentiation - drug effects | Models, Biological | Isoproterenol - pharmacology | Ryanodine Receptor Calcium Release Channel - chemistry | Tachycardia, Ventricular - pathology | Mice, Inbred NOD | Fibroblasts - cytology | Mice | Sarcoplasmic Reticulum Calcium-Transporting ATPases - genetics | Medical research | Stem cells | Medicine, Experimental | Ventricular tachycardia | Models | Medical screening | Electric fields | Health aspects | Cardiac arrhythmia | Biotechnology | Phosphorylation | Transcription factors | Science | Action potential | Isoproterenol | Rodents | Fibroblasts | Physiology | Cardiology | Deoxyribonucleic acid--DNA | University graduates | Phenotypes | Incubation | Calcium imaging | Cardiomyocytes | Pharmacology | Gene expression | Chemical compounds | Patients | Medicine | Tachycardia | Mutation | Ventricle | Pluripotency | Calcium ions | Deoxyribonucleic acid | DNA
Journal Article
PloS one, ISSN 1932-6203, 2012, Volume 7, Issue 11, p. e48872
Background: Traditional Chinese medicinal herbs Cortex Moutan and Radix Salviae Milthiorrhizaeare are prescribed together for their putative cardioprotective... 
OXIDATIVE STRESS | HEART-DISEASE | INDUCED CARDIOTOXICITY | INFARCTION | SALVIA-MILTIORRHIZA | REACTIVE OXYGEN | ACID | MULTIDISCIPLINARY SCIENCES | LIPID PEROXIDES | CARDIOVASCULAR-DISEASE | GLUTATHIONE PEROXIDASE | Immunohistochemistry | Myocardial Infarction - blood | Glutathione - metabolism | Antioxidants - metabolism | Caspase 3 - metabolism | Body Weight - drug effects | Male | Myocardial Infarction - diagnostic imaging | Isoproterenol | Cardiotonic Agents - therapeutic use | Myocardial Infarction - pathology | Acetophenones - pharmacology | Lipid Peroxidation - drug effects | Ultrasonography | Electrocardiography | Drug Therapy, Combination | Lactates - chemistry | Lactates - pharmacology | bcl-2-Associated X Protein - metabolism | Rats | Lactates - therapeutic use | Myocardium - pathology | Thiobarbituric Acid Reactive Substances - metabolism | Cardiotonic Agents - chemistry | Biomarkers - blood | Cardiotonic Agents - pharmacology | Rats, Sprague-Dawley | Myocardium - enzymology | Organ Size - drug effects | Animals | Myocardial Infarction - drug therapy | Acetophenones - chemistry | Acetophenones - therapeutic use | NF-E2-Related Factor 2 - metabolism | Troponin I - metabolism | Antioxidants | Medicinal plants | Creatine kinase | Cardiotonic agents | Electrocardiogram | Medicine, Botanic | Medicine, Herbal | Heart attack | Cardiac glycosides | Myocardial infarction | Heart | Oxidative stress | Heart attacks | Bax protein | Bcl-2 protein | Lipid peroxidation | Lipids | Cardiovascular disease | Retailing | Caspase-3 | Elevation | Ischemia | Rodents | Animal tissues | Gangrene | Pretreatment | EKG | Enzymes | Free radicals | Pentobarbital sodium | Medicinal herbs | Traditional Chinese medicine | Caspase | Gene expression | Angina pectoris | Studies | Herbal medicine | Signaling | Sodium | Neural networks | Pentobarbital | Pharmacy | Infarction | Combinatorial analysis | Apoptosis
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 03/2018, Volume 45, Issue 4, pp. 1455 - 1471
Journal Article