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1. Full Text Synthesis of Azaheterocycles from Aryl Ketone O-Acetyl Oximes and Internal Alkynes by Cu–Rh Bimetallic Relay Catalysts
by Too, Pei Chui and Chua, Sze Hui and Wong, Siong Heng and Chiba, Shunsuke
Journal of organic chemistry, ISSN 0022-3263, 08/2011, Volume 76, Issue 15, pp. 6159 - 6168
Organic chemistry | Chemistry | Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry | Heterocyclic compounds | Heterocyclic compounds with only one n hetero atom and condensed derivatives | Exact sciences and technology | General and physical chemistry | Catalysis | Heterocyclic compounds with n hetero atom and also o and/or s, se, te hetero atoms | Catalysts: preparations and properties | Preparations and properties | Carbolines - chemical synthesis | Pyrimidines - chemical synthesis | Heterocyclic Compounds - chemical synthesis | Alkynes - chemistry | Pyrimidines - chemistry | Oximes - chemistry | Isoquinolines - chemistry | Carbolines - chemistry | Copper - chemistry | Heterocyclic Compounds - chemistry | Isoquinolines - chemical synthesis | Ketones - chemistry | Organometallic Compounds - chemistry | Molecular Structure | Rhodium - chemistry | Ketones | Analysis | Chemical properties | Copper | Structure | Index Medicus
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2. Full Text Rhodium(III)‐Catalyzed Intramolecular Annulation through CH Activation: Total Synthesis of (±)‐Antofine, (±)‐Septicine, (±)‐Tylophorine, and Rosettacin
by Xu, Xianxiu and Liu, Yu and Park, Cheol‐Min
Angewandte Chemie (International ed.), ISSN 1433-7851, 09/2012, Volume 51, Issue 37, pp. 9372 - 9376
CH activation | annulation | isoquinolones | 2‐pyridones | rhodium | C-H activation | 2-pyridones | Stereoisomerism | Heterocyclic Compounds, 4 or More Rings - chemistry | Indoles - chemical synthesis | Alkaloids - chemical synthesis | Alkynes - chemistry | Heterocyclic Compounds, 4 or More Rings - chemical synthesis | Indolizines - chemical synthesis | Hydrogen - chemistry | Carbon - chemistry | Phenanthrolines - chemical synthesis | Isoquinolines - chemistry | Phenanthrenes - chemistry | Phenanthrenes - chemical synthesis | Cyclization | Phenanthrolines - chemistry | Indolizines - chemistry | Catalysis | Pyridones - chemistry | Indoles - chemistry | Alkaloids - chemistry | Rhodium - chemistry | Index Medicus | Organic chemistry | Synthesis | Oxidants | Chemical reactions | Esters | Activation | Tolerances | Alkynes
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3. Full Text One‐Pot Synthesis of Isoquinolinium Salts by Rhodium‐Catalyzed CH Bond Activation: Application to the Total Synthesis of Oxychelerythrine
by Jayakumar, Jayachandran and Parthasarathy, Kanniyappan and Cheng, Chien‐Hong
Angewandte Chemie (International ed.), ISSN 1433-7851, 01/2012, Volume 51, Issue 1, pp. 197 - 200
CH activation | annulation | heterocycles | alkynes | rhodium | C-H activation | Amines - chemistry | Benzaldehydes - chemistry | Alkynes - chemistry | Hydrogen - chemistry | Carbon - chemistry | Salts - chemistry | Isoquinolines - chemistry | Benzophenanthridines - chemical synthesis | Benzophenanthridines - chemistry | Cyclization | Isoquinolines - chemical synthesis | Catalysis | Rhodium - chemistry | Index Medicus
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4. Full Text Cationic Ruthenium Catalysts for Alkyne Annulations with Oximes by C–H/N–O Functionalizations
by Kornhaaß, Christoph and Li, Jie and Ackermann, Lutz
Journal of organic chemistry, ISSN 0022-3263, 10/2012, Volume 77, Issue 20, pp. 9190 - 9198
Chemistry | General and physical chemistry | Catalysis | Theory of reactions, general kinetics. Catalysis. Nomenclature, chemical documentation, computer chemistry | Catalysts: preparations and properties | Exact sciences and technology | Oximes - chemistry | Isoquinolines - chemistry | Cations - chemistry | Cyclization | Isoquinolines - chemical synthesis | Organometallic Compounds - chemistry | Alkynes - chemistry | Molecular Structure | Ruthenium - chemistry | Chemical bonds | Ruthenium | Ring formation (Chemistry) | Chemical properties | Analysis | Index Medicus
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5. Full Text Two Annulated Azaheterocyclic Cores Readily Available from a Single Tetrahydroisoquinolonic Castagnoli-Cushman Precursor
by Karchuganova, Elizaveta and Bakulina, Olga and Dar'in, Dmitry and Krasavin, Mikhail
Molecules (Basel, Switzerland), ISSN 1420-3049, 05/2020, Volume 25, Issue 9, p. 2049
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Magnetic Resonance Spectroscopy | Quinolines - chemistry | Sulfides - chemistry | Hydroxamic Acids - chemistry | Lactams | Chemistry, Pharmaceutical | Isoquinolines - chemistry | Chemistry, Organic | Cyclization | Tetrahydroisoquinolines - chemistry | Nitrogen Compounds - chemistry | Drug Design | Molecular Structure | Indole Alkaloids - chemistry | Indoles - chemistry | Sulfide | Solvents | Reduction | Ammonium | Acids | Dehydrogenation | Decarboxylation | Tetrahydroisoquinoline | Carboxylic acids | Sulfur | Sodium sulfide | Index Medicus | nitroarene reduction | hydroxamic acid | indoloisoquinoline | Castagnoli–Cushman reaction | tetrahydroisoquinolonic acid | heteroannulation
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6. Full Text Reactions of aromatic N-heterocycles with d0fn-metal alkyl complexes supported by chelating diamide ligands
by Diaconescu, Paula L
Accounts of chemical research, ISSN 0001-4842, 10/2010, Volume 43, Issue 10, pp. 1352 - 1363
Isoquinolines - chemistry | Heterocyclic Compounds - chemistry | Metals - chemistry | Pyridines - chemistry | Chelating Agents - chemistry | Diamide - chemistry | Imidazoles - chemistry | Ligands | Ferrous Compounds - chemistry | Metallocenes | Uranium - chemistry | Coordination Complexes - chemistry | Index Medicus
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7. Full Text Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family
by Koutova, Darja and Maafi, Negar and Havelek, Radim and Opletal, Lubomir and Blunden, Gerald and Rezacova, Martina and Cahlikova, Lucie
Molecules (Basel, Switzerland), ISSN 1420-3049, 05/2020, Volume 25, Issue 10, p. 2337
Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Chemistry, Multidisciplinary | Science & Technology | Plant Extracts - chemistry | Phenanthridines - chemistry | Humans | Cholinesterase Inhibitors - chemistry | Phenanthridines - pharmacology | Heterocyclic Compounds, 4 or More Rings - pharmacology | Phenanthridines - isolation & purification | Galantamine - pharmacology | Amaryllidaceae Alkaloids - chemistry | Isoquinolines - chemistry | Isoquinolines - pharmacology | Amaryllidaceae - metabolism | Galantamine - chemistry | Inhibitory Concentration 50 | Cholinesterase Inhibitors - isolation & purification | Amaryllidaceae - chemistry | Heterocyclic Compounds, 4 or More Rings - chemistry | Nootropic Agents - isolation & purification | Amaryllidaceae Alkaloids - pharmacology | Antineoplastic Agents, Phytogenic - chemistry | Galantamine - isolation & purification | Antiprotozoal Agents - chemistry | Nootropic Agents - chemistry | Antiprotozoal Agents - pharmacology | Antiprotozoal Agents - isolation & purification | Heterocyclic Compounds, 4 or More Rings - isolation & purification | Secondary Metabolism | Cholinesterase Inhibitors - pharmacology | Cell Line, Tumor | Amaryllidaceae Alkaloids - isolation & purification | Antineoplastic Agents, Phytogenic - pharmacology | Nootropic Agents - pharmacology | Antineoplastic Agents, Phytogenic - isolation & purification | Isoquinolines - isolation & purification | Medicinal plants | Biological properties | Galantamine | Neurodegenerative diseases | Low concentrations | Cytotoxicity | Biosynthesis | Breast cancer | Acetylcholinesterase | Studies | Alkaloids | Secondary metabolites | Metabolites | Cell lines | Alzheimer's disease | Index Medicus | derivatives | biological activity | montanine | Amaryllidaceae | alkaloids | montanine-type
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8. Full Text Therapeutic potential of nucleic acid‐binding isoquinoline alkaloids: Binding aspects and implications for drug design
by Bhadra, Kakali and Kumar, Gopinatha Suresh
Medicinal research reviews, ISSN 0198-6325, 11/2011, Volume 31, Issue 6, pp. 821 - 862
isoquinoline alkaloids | calorimetry | therapeutic implications | spectroscopy | drug design | alkaloids–nucleic acid interaction | Spectroscopy | Calorimetry | Drug design | Isoquinoline alkaloids | Therapeutic implications | Alkaloids-nucleic acid interaction | Pharmacology & Pharmacy | Life Sciences & Biomedicine | Chemistry, Medicinal | Science & Technology | Berberine - chemistry | Temperature | Chemistry, Pharmaceutical - methods | Models, Chemical | Humans | Spectrophotometry - methods | RNA - chemistry | Calorimetry - methods | Isoquinolines - chemistry | DNA - chemistry | Animals | Benzophenanthridines - chemistry | Berberine - analogs & derivatives | Nucleic Acids - chemistry | Drug Design | Berberine Alkaloids - chemistry | Mice | Alkaloids - chemistry | Alkaloids | Berberine | natural products | Reviews | DNA | Data processing | sanguinarine | Drug discovery | nucleic acids | Drug development | Index Medicus
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9. Full Text Harnessing insulin-and leptin-induced oxidation of PTP1B for therapeutic development
by Krishnan, Navasona and Bonham, Christopher A and Rus, Ioana A and Shrestha, Om Kumar and Gauss, Carla M and Haque, Aftabul and Tocilj, Ante and Joshua-Tor, Leemor and Tonks, Nicholas K
Nature communications, ISSN 2041-1723, 12/2018, Volume 9, Issue 1, pp. 283 - 17
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Levamisole - chemistry | Hypoglycemic Agents - metabolism | Humans | Leptin - metabolism | Crystallography, X-Ray | Small Molecule Libraries - metabolism | Isoquinolines - chemistry | Single-Chain Antibodies - metabolism | Levamisole - metabolism | Single-Chain Antibodies - genetics | Benzophenanthridines - chemistry | Enzyme Inhibitors - chemistry | Cloning, Molecular | Escherichia coli - metabolism | Protein Interaction Domains and Motifs | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - genetics | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - chemistry | Binding Sites | Anti-Obesity Agents - metabolism | Isoquinolines - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Leptin - chemistry | Enzyme Inhibitors - metabolism | Oxidation-Reduction | Protein Structure, Secondary | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - antagonists & inhibitors | Recombinant Proteins - chemistry | Hypoglycemic Agents - chemistry | Recombinant Proteins - genetics | Small Molecule Libraries - chemistry | Anti-Obesity Agents - chemistry | Insulin - metabolism | Protein Tyrosine Phosphatase, Non-Receptor Type 1 - metabolism | Escherichia coli - genetics | Insulin - chemistry | Protein Binding | Molecular Docking Simulation | Benzophenanthridines - metabolism | Single-Chain Antibodies - chemistry | Tyrosine | Intervention | Obesity | Energy metabolism | Diabetes mellitus | Homeostasis | Metabolism | Insulin | Glucose metabolism | Signaling | Inhibitors | Leptin | Oxidation | Diabetes | Protein-tyrosine-phosphatase | Index Medicus
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10. Full Text Testing Fluorescence Lifetime Standards using Two-Photon Excitation and Time-Domain Instrumentation: Rhodamine B, Coumarin 6 and Lucifer Yellow
by Kristoffersen, Arne S and Erga, Svein R and Hamre, Børge and Frette, Øyvind
Journal of fluorescence, ISSN 1053-0509, 7/2014, Volume 24, Issue 4, pp. 1015 - 1024
Biochemistry, general | Biotechnology | Analytical Chemistry | Lifetime | Biomedicine | Time-domain | Fluorescence | Biophysics and Biological Physics | Two-photon | Biomedicine general | Biochemistry & Molecular Biology | Physical Sciences | Chemistry | Life Sciences & Biomedicine | Biochemical Research Methods | Chemistry, Analytical | Chemistry, Physical | Science & Technology | Protons | Fluorescent Dyes - chemistry | Isoquinolines - chemistry | Time Factors | Spectrometry, Fluorescence | Coumarins - chemistry | Thiazoles - chemistry | Rhodamines - chemistry | Usage | Index Medicus | Rhodamine | Decay | Ethyl alcohol | Excitation | Coumarin | Chemical compounds | Standards | Original Paper
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11. Full Text Effect of HM30181 mesylate salt-loaded microcapsules on the oral absorption of paclitaxel as a novel P-glycoprotein inhibitor
by Kim, Jin Cheul and Kim, Kyeong Soo and Kim, Dong Shik and Jin, Sung Giu and Kim, Dong Wuk and Kim, Yong Il and Park, Jae-Hyun and Kim, Jong Oh and Yong, Chul Soon and Youn, Yu Seok and Woo, Jong Soo and Choi, Han-Gon
International journal of pharmaceutics, ISSN 0378-5173, 06/2016, Volume 506, Issue 1-2, pp. 93 - 101
HM30181 mesylate salt | Bioavailability | Microcapsule | Paclitaxel | Solubility | P-glycoprotein inhibitor | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | Paclitaxel - metabolism | Paclitaxel - pharmacology | Capsules - pharmacology | Lactose - analogs & derivatives | Capsules - metabolism | Methylcellulose - analogs & derivatives | Biological Availability | Male | Drug Carriers - chemistry | Benzopyrans - chemistry | Isoquinolines - chemistry | Paclitaxel - chemistry | Tetrazoles - chemistry | ATP Binding Cassette Transporter, Sub-Family B - antagonists & inhibitors | Powders - pharmacology | Administration, Oral | Silicon Dioxide - chemistry | Phosphoric Acids - chemistry | Rats | Capsules - chemistry | Mesylates - chemistry | Rats, Sprague-Dawley | Powders - chemistry | Methylcellulose - chemistry | Animals | Lactose - chemistry | Polymers - chemistry | Antimitotic agents | Drugstores | Antineoplastic agents | Pharmacy | Phosphates | Phosphoric acid | Powders | Polymers | Silica | Index Medicus
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