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Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 04/2007, Volume 34, Issue 4, pp. 339 - 346
SUMMARY • In the present study, we investigated the effects of the inducible nitric oxide (iNOS) inhibitors S-methylisothiourea (SMT)... 
free radicals | acute lung injury | pro-inflammatory cytokines | endotoxaemia | inducible nitric oxide synthase | pro‐inflammatory cytokines | Pro-inflammatory cytokines | Acute lung injury | Endotoxaemia | Free radicals | Inducible nitric oxide synthase | PHYSIOLOGY | PEROXYNITRITE | GUINEA-PIGS | SEPSIS | CONSCIOUS RATS | FREE-RADICALS | ACUTE PULMONARY-EDEMA | MODELS | SEPTIC SHOCK | LIPOPOLYSACCHARIDE | PHARMACOLOGY & PHARMACY | EXPRESSION | Respiratory Distress Syndrome, Adult - pathology | Endotoxemia - prevention & control | Lipopolysaccharides - administration & dosage | Tumor Necrosis Factor-alpha - blood | Endotoxemia - chemically induced | Male | Interleukin-1beta - blood | Enzyme Inhibitors - administration & dosage | Nitric Oxide Synthase Type II - antagonists & inhibitors | Nitrites - blood | Pulmonary Edema - prevention & control | Interleukin-1beta - biosynthesis | Lung - metabolism | Isothiuronium - administration & dosage | Nitrates - blood | Lysine - analogs & derivatives | Lung - pathology | Lipopolysaccharides - toxicity | Methylguanidine - blood | Respiratory Distress Syndrome, Adult - chemically induced | Respiratory Distress Syndrome, Adult - prevention & control | Isothiuronium - analogs & derivatives | Enzyme Inhibitors - pharmacology | Lysine - administration & dosage | Rats | Rats, Sprague-Dawley | Organ Size - drug effects | Pulmonary Edema - chemically induced | Animals | Lysine - pharmacology | Pulmonary Edema - blood | Lung - drug effects | Endotoxemia - blood | Infusions, Intravenous | Nitric Oxide - metabolism | Tumor Necrosis Factor-alpha - biosynthesis | Endotoxins - toxicity | Isothiuronium - pharmacology | Interleukin-1beta, blood | Isothiuronium, administration and dosage | Lysine, pharmacology | Pulmonary Edema, prevention and control | Methylguanidine, blood | Organ Size, drug effects | Isothiuronium, analogs and derivatives | Enzyme Inhibitors, pharmacology | Lung, drug effects | Lysine, analogs and derivatives | Lipopolysaccharides, administration and dosage | Lysine, administration and dosage | Tumor Necrosis Factor-alpha, biosynthesis | Tumor Necrosis Factor-alpha, blood | Interleukin-1beta, biosynthesis | Nitrites, blood | Respiratory Distress Syndrome, Adult, prevention and control | Isothiuronium, pharmacology | Pulmonary Edema, chemically induced | Respiratory Distress Syndrome, Adult, chemically induced | Nitric Oxide Synthase Type II, antagonists and inhibitors | Nitric Oxide, metabolism | Lung, pathology | Nitrates, blood | Endotoxins, toxicity | Lipopolysaccharides, toxicity | Endotoxemia, prevention and control | Lung, metabolism | Pulmonary Edema, blood | Endotoxemia, blood | Endotoxemia, chemically induced | Respiratory Distress Syndrome, Adult, pathology | Enzyme Inhibitors, administration and dosage | Nitric oxide
Journal Article
Arkivoc, ISSN 1551-7012, 11/2010, Volume 2010, Issue 11, pp. 303 - 321
The reactivity profile of allylic bromides (derived from the Morita-Baylis-Hillman reaction) towards thiourea derivatives and further transformations of the... 
Isothiuronium salt | Aqueous solvent | Allylic bromide | 1,3-thiazinone | REACTION-PRODUCT | AZIDES | ANION | RECOGNITION | ONE-POT SYNTHESIS | BAYLIS-HILLMAN REACTION | CHEMISTRY, ORGANIC | aqueous solvent | THIOUREAS | isothiuronium salt | DERIVATIVES | EFFICIENT | CYCLIZATION
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 06/2010, Volume 333, Issue 3, pp. 650 - 662
Journal Article
Journal Article
Shock, ISSN 1073-2322, 01/2006, Volume 25, Issue 1, pp. 43 - 49
The molecular mechanisms that mediate gram-negative sepsis-associated myocardial dysfunction remain elusive. Myocardial expression of inflammatory mediators is... 
Myocardial depression | Sepsis | Cardiac myocyte contractility | E5564 | LPS | SURGERY | ADULT HEART | cardiac myocyte contractility | CARDIAC MYOCYTES | FACTOR-ALPHA | SIGNAL-TRANSDUCTION | myocardial depression | TUMOR-NECROSIS-FACTOR | LEFT-VENTRICULAR DYSFUNCTION | IN-VIVO | SEPTIC SHOCK | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | sepsis | INNATE IMMUNITY | CRITICAL CARE MEDICINE | Lipid A - analogs & derivatives | NF-kappa B - metabolism | Endotoxemia - pathology | Cardiomyopathies - etiology | Sarcomeres - pathology | Toll-Like Receptor 4 - deficiency | Nitric Oxide Synthase Type II - antagonists & inhibitors | Myocardium - metabolism | Toll-Like Receptor 4 - antagonists & inhibitors | Myocardial Contraction | Gram-Negative Bacterial Infections - pathology | Isothiuronium - analogs & derivatives | Sarcomeres - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Gram-Negative Bacterial Infections - complications | Cardiomyopathies - pathology | Myocardium - pathology | Gram-Negative Bacterial Infections - metabolism | Toll-Like Receptor 4 - metabolism | Myocytes, Cardiac - pathology | Animals | Endotoxemia - complications | Cardiomyopathies - metabolism | Lipid A - pharmacology | Lipopolysaccharides - pharmacology | Myocytes, Cardiac - metabolism | Mice | Endotoxemia - metabolism | Nitric Oxide - metabolism | Isothiuronium - pharmacology | Nitric Oxide Synthase Type II - metabolism
Journal Article
Journal Article
Journal of Molecular Neuroscience, ISSN 0895-8696, 2/2012, Volume 46, Issue 2, pp. 336 - 342
Nitric oxide has been investigated widely both during neurodevelopment and in neurological diseases. However, whilst it has been established that nitric... 
Neurochemistry | Cerebellum | Neurology | Neurosciences | Biomedicine | Neurite | Nitric oxide | Proteomics | Purkinje | Cell Biology | Apoptosis | INDUCED NEURITE OUTGROWTH | PEROXYNITRITE | BIOCHEMISTRY & MOLECULAR BIOLOGY | NEUROSCIENCES | SYNTHASE | S-NITROSYLATION | MUTANT MICE | DISEASE | INDUCED NEUROTOXICITY | RAT-BRAIN | GRANULE CELLS | EXPRESSION | Citrulline - analogs & derivatives | Nitric Oxide - pharmacology | Purkinje Cells - ultrastructure | Cell Count | Nitric Oxide Donors - toxicity | Nitric Oxide Synthase - antagonists & inhibitors | Nitric Oxide Synthase - physiology | Nitroso Compounds - toxicity | Isothiuronium - toxicity | Citrulline - toxicity | Purkinje Cells - enzymology | Cerebellar Cortex - embryology | Cells, Cultured - ultrastructure | Neurites - ultrastructure | Female | Imidazoles - toxicity | Purkinje Cells - drug effects | Neurites - drug effects | Nerve Tissue Proteins - antagonists & inhibitors | Cells, Cultured - drug effects | Nerve Tissue Proteins - physiology | Cerebellar Cortex - cytology | Isothiuronium - analogs & derivatives | Mice, Inbred C57BL | Peroxynitrous Acid - toxicity | Nitric Oxide - toxicity | Cells, Cultured - enzymology | Pregnancy | Animals | Benzoates - toxicity | Mice | Reactive Nitrogen Species - toxicity | Nerve Degeneration | Thiourea - analogs & derivatives | Thiourea - toxicity | Physiological aspects | Research | Purkinje cells | Index Medicus | Cell culture | Enzymes | Peroxynitrite | Cell survival | Axonogenesis | Nervous system | Nitric-oxide synthase | Neurological diseases | Axons | Neural networks
Journal Article
Journal Article
Journal Article