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Circulation Research, ISSN 0009-7330, 08/2009, Volume 105, Issue 4, pp. 365 - 374
RATIONALE:The recent emergence of hydrogen sulfide (H2S) as a potent cardioprotective signaling molecule necessitates the elucidation of its cytoprotective... 
Hydrogen sulfide | Myocardial infarction | Cardioprotection | Nrf2 | Antioxidant signaling | PROTEIN-KINASE-C | OXIDATIVE STRESS | ISCHEMIA/REPERFUSION INJURY | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | myocardial infarction | INDUCTION | antioxidant signaling | ISCHEMIA-REPERFUSION INJURY | JAK-STAT PATHWAY | hydrogen sulfide | ANTIOXIDANT | cardioprotection | PERIPHERAL VASCULAR DISEASE | MYOCARDIAL INJURY | RAT-HEART | HEMATOLOGY | HSP90 Heat-Shock Proteins - biosynthesis | Oxidative Stress | Air Pollutants - pharmacology | Male | Cyclooxygenase 2 - biosynthesis | bcl-Associated Death Protein - biosynthesis | Cell Nucleus - metabolism | Thioredoxins - biosynthesis | Time Factors | Protein Kinase C - metabolism | bcl-X Protein - biosynthesis | Phosphorylation - drug effects | HSP70 Heat-Shock Proteins - biosynthesis | Hydrogen Sulfide - pharmacology | Heme Oxygenase-1 - biosynthesis | Cardiotonic Agents - pharmacology | Myocardial Infarction - metabolism | Mice, Inbred ICR | Mice, Knockout | Gene Expression Regulation - drug effects | STAT3 Transcription Factor - biosynthesis | Myocardial Reperfusion Injury - metabolism | Animals | Signal Transduction - drug effects | Active Transport, Cell Nucleus - drug effects | NF-E2-Related Factor 2 - metabolism | Mice | Myocardial Infarction - prevention & control | Troponin I - metabolism | Myocardial Reperfusion Injury - prevention & control | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 05/2013, Volume 32, Issue 21, pp. 2601 - 2613
The Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway is central to signaling by cytokine receptors, a superfamily of more... 
hematological malignancies | leukemia | JAK/STAT | COLONY-STIMULATING FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | ERYTHROPOIETIN RECEPTOR ACTIVATION | ACUTE MYELOID-LEUKEMIA | PROTEIN-TYROSINE KINASE | OF-FUNCTION MUTATIONS | CELL BIOLOGY | ONCOLOGY | ACUTE LYMPHOBLASTIC-LEUKEMIA | HEMATOPOIETIC STEM-CELLS | GENETICS & HEREDITY | ACUTE MEGAKARYOBLASTIC LEUKEMIA | ACQUIRED UNIPARENTAL DISOMY | CLASSICAL HODGKIN LYMPHOMA | Gene Expression Regulation, Enzymologic - drug effects | Janus Kinase 2 - biosynthesis | Hodgkin Disease - genetics | Humans | STAT Transcription Factors - metabolism | Mutation, Missense | Neoplasm Proteins - metabolism | Precursor Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Precursor Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Hodgkin Disease - drug therapy | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Gene Expression Regulation, Neoplastic - genetics | Hematologic Neoplasms - metabolism | Janus Kinase 2 - antagonists & inhibitors | Hodgkin Disease - metabolism | Signal Transduction | Janus Kinase 2 - genetics | Exons - genetics | Precursor Cell Lymphoblastic Leukemia-Lymphoma - genetics | STAT Transcription Factors - genetics | Animals | Gene Expression Regulation, Enzymologic - genetics | Protein Kinase Inhibitors - therapeutic use | Hematologic Neoplasms - drug therapy | Hematologic Neoplasms - genetics | Amino Acid Substitution | Physiological aspects | Lymphomas | Research | Leukemia | Analysis | STAT proteins | Signal transduction | Gene expression | Multiple myeloma
Journal Article
Nature medicine, ISSN 1078-8956, 10/2014, Volume 20, Issue 10, pp. 1174 - 1181
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2016, Volume 197, Issue 1, pp. 11 - 18
Journal Article
Biochemical Journal, ISSN 0264-6021, 01/2006, Volume 393, Issue 1, pp. 7 - 20
Leptin is a versatile 16 kDa peptide hormone, with a tertiary structure resembling that of members of the long-chain helical cytokine family. It is mainly... 
Adipocyte | Obesity | Leptin receptor | Signalling cascade | Cytokine | Janus kinase/signal transducer and activator of transcription pathway (JAK/STAT pathway) | cytokine | LONG-FORM | leptin receptor | PROTEIN-KINASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED OBESITY | BODY-WEIGHT | TYROSINE-PHOSPHATASE 1B | FATTY-ACID OXIDATION | adipocyte | signalling cascade | RECEPTOR OB-R | GROWTH-FACTOR | obesity | COLONIC EPITHELIAL-CELLS | ADIPOSE-TISSUE | Receptors, Leptin | Animals | Humans | Leptin - metabolism | Gene Expression Regulation | Protein Binding | Receptors, Cell Surface - metabolism | Signal Transduction - physiology | ACC, acetyl-CoA carboxylase | PI3K, phosphoinositide 3-kinase | OSM, oncostatin-M | SHP-2, SH2 domain-containing protein tyrosine phosphatase | AMPK, 5′-AMP-activated protein kinase | CT-1, cardiotrophin-1 | Review | JNK, c-Jun N-terminal kinase | NPY, neuropeptide Y | PTP1B, protein tyrosine phosphatase 1B | PDE, phosphodiesterase | ERK, extracellular-signal-regulated kinase | SH2, Src-like homology 2 | Janus kinase | TNFα, tumour necrosis factor α | PKC, protein kinase C | NF-κB, nuclear factor κB | STAT, signal transducer and activator of transcription | STAT pathway | VEGF, vascular endothelial growth factor | SOCS, suppressor of cytokine signalling | JAK, Janus kinase | TYK2, tyrosine kinase 2 | signal transducer and activator of transcription pathway (JAK | HIF-1α, hypoxia-inducible factor 1α | IL, interleukin | LIF, leukaemia inhibitory factor | CNTF, ciliary neurotrophic factor | MAPK, mitogen-activated protein kinase | PKA, protein kinase A | IRS, insulin receptor substrate
Journal Article