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Journal of Medicinal Chemistry, ISSN 0022-2623, 01/2019, Volume 62, Issue 2, pp. 1054 - 1066
JAK family kinases are important mediators of immune cell signaling and Janus Kinase 3 (JAK3) has long been indicated as a potential target for autoimmune... 
JAK3 | POTENT | CHEMISTRY, MEDICINAL
Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 11/2019, p. 115236
Journal Article
Journal Article
Molecular Immunology, ISSN 0161-5890, 09/2018, Volume 101, pp. 386 - 395
Indirubin (IR) is a bisindole compound extracted from the leaves of Chinese herb . has been widely used in traditional Chinese medicine to treat inflammatory... 
Jak3/Stat3 | γδT cell | IL-17A | Indirubin | Psoriasis
Journal Article
Journal of Inflammation, ISSN 1476-9255, 2010, Volume 7, Issue 1, pp. 41 - 41
Background: The Janus kinase (JAK) family of tyrosine kinases includes JAK1, JAK2, JAK3 and TYK2, and is required for signaling through Type I and Type II... 
RHEUMATOID-ARTHRITIS | DOSE-ESCALATION | APOPTOSIS | ACTIVATION | SYNOVIAL-FLUID | IMMUNOSUPPRESSION | MONOCLONAL-ANTIBODY | KINASE INHIBITOR | IMMUNOLOGY | CP-690550 | JAK3
Journal Article
Cellular Physiology and Biochemistry, ISSN 1015-8987, 08/2015, Volume 37, Issue 1, pp. 297 - 305
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 8/2013, Volume 191, Issue 3, pp. 1164 - 1174
The role of Janus kinase (JAK)-3 in TLR-mediated innate immune responses is poorly understood, although the suppressive function of JAK3 inhibition in adaptive... 
Inflammatory cytokines | PI3K | GSK3 | JAK3 | TLR4
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 05/2018, Volume 89, pp. 21 - 29
We analyzed the transcriptome of detailed CD4 T cell subsets including them after abatacept treatment, and examined the difference among CD4 T cell subsets and... 
Zap70 | T cell receptor | Abatacept | JAK3 | Rheumatoid arthritis | RESPONSES | ACTIVATION | INHIBITION | IMMUNOLOGY | EXPRESSION
Journal Article
CLINICAL IMMUNOLOGY, ISSN 1521-6616, 02/2016, Volume 163, pp. 91 - 95
Severe combined immune deficiency (SCID) is a group of genetically heterogeneous diseases caused by an early block in T cell differentiation and present with... 
EXON | Mis-splicing mutations | IMMUNOLOGY | SCID | JAK3 | DEFICIENCY | FAMILY
Journal Article
BLOOD, ISSN 0006-4971, 10/2019, Volume 134, Issue 14, pp. 1132 - 1143
T-cell prolymphocytic leukemia (T-PLL) is a rare, mature T-cell neoplasm with a heterogeneous clinical course. With the advent of novel treatment options that... 
ALEMTUZUMAB | GENE | GUIDELINES | CHRONIC LYMPHOCYTIC-LEUKEMIA | MALIGNANCIES | MUTATIONS | HEMATOLOGY | EXPRESSION | JAK3 | CHROMOSOMAL IMBALANCES | TRANSPLANTATION | Life Sciences | Hematology | Human health and pathology
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 04/2018, Volume 115, Issue 17, pp. 4305 - 4307
Journal Article
Cellular and Molecular Life Sciences, ISSN 1420-682X, 1/2016, Volume 73, Issue 2, pp. 253 - 269
Journal Article
The Journal of allergy and clinical immunology, ISSN 0091-6749, 7/2017, Volume 140, Issue 1, pp. 268 - 271.e6
Journal Article