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Free Radical Biology and Medicine, ISSN 0891-5849, 07/2017, Volume 108, pp. S89 - S89
Journal Article
Oncogene, ISSN 0950-9232, 07/2012, Volume 31, Issue 27, pp. 3287 - 3297
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 07/2018, Volume 54, Issue 57, pp. 7975 - 7978
Jumonji domain-containing demethylases (JmjC-KDMs) catalyse demethylation of Nε-methylated lysines on histones and play important roles in gene regulation. We... 
Journal Article
Frontiers in Immunology, ISSN 1664-3224, 2018, Volume 9, p. 2272
Sepsis, defined as life-threatening organ dysfunction, is one of the most common causes of mortality in intensive care units with limited therapeutic options.... 
JMJD3 | Sepsis | MiR-146a | Inflammation | GSKJ4 | RESPONSES | INHIBITION | inflammation | DEMETHYLASE JMJD3 | miR-146a | INDUCTION | IMMUNOLOGY | EXPRESSION | sepsis | MESENCHYMAL STEM-CELLS | Epigenetic inheritance | Genetic aspects | MicroRNA | Research | Genetic transcription
Journal Article
Archives of Oral Biology, ISSN 0003-9969, 09/2018, Volume 93, pp. 87 - 94
To investigate the role of the histone 3 lysine 27 trimethylation (H3K27me3) demethylase Jumonji domain-containing protein 3 (Jmjd3) in the epigenetic... 
Human periodontal ligament cells | Epigenetics | Inflammation | Jmjd3 | PERIAPICAL LESIONS | DEMETHYLASE JMJD3 | DENTISTRY, ORAL SURGERY & MEDICINE | APICAL PERIODONTITIS | EXPRESSION | FIBROBLASTS | IL-6 | Interleukins
Journal Article
CELL STEM CELL, ISSN 1934-5909, 07/2012, Volume 11, Issue 1, pp. 50 - 61
Human bone marrow mesenchymal stem/stromal cells (MSCs) are multipotent progenitor cells with multilineage differentiation potentials including osteogenesis... 
JMJD3 | OSTEOBLASTOGENESIS | BONE-MARROW | TISSUE | GENE-EXPRESSION | PPAR-GAMMA | KAPPA-B | STROMAL CELLS | TRANSCRIPTIONAL REGULATION | MESENCHYMAL STEM-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
Oncotarget, ISSN 1949-2553, 09/2017, Volume 8, Issue 37, pp. 62131 - 62142
Androgen receptor (AR) mediates initiation and progression of prostate cancer (PCa); AR-driven transcription is activated by binding of androgens to the... 
GSK-J4 | H3K27Me2/3 | Cabazitaxel | Castration resistant prostate cancer | JMJD3/UTX | ANDROGEN RECEPTOR | ACTIVATION | VARIANTS | castration resistant prostate cancer | HISTONE DEMETHYLASES | OPEN-LABEL | COMBINATION | PACLITAXEL | CELL BIOLOGY | TRIAL | EXPRESSION
Journal Article
BIOCHEMICAL JOURNAL, ISSN 0264-6021, 06/2019, Volume 476, Issue 12, pp. 1741 - 1751
Podocytes are terminally differentiated and highly specialized glomerular cells, which have an essential role as a filtration barrier against proteinuria.... 
JMJD3 | NEPHRIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INJURY | UTX | EXPRESSION | CELL BIOLOGY | INSIGHTS
Journal Article
Journal of Cerebral Blood Flow & Metabolism, ISSN 0271-678X, 12/2017, Volume 37, Issue 12, pp. 3695 - 3708
The blood–brain barrier (BBB) exhibits a highly selective permeability to support the homeostasis of the central nervous system (CNS). The tight junctions in... 
dexamethasone | tight junction disruption | blood–brain barrier | Jmjd3 | negative GRE | blood-brain barrier | BARRIER IN-VITRO | NEUROSCIENCES | SUMO-SMRT/NCOR1-HDAC3 REPRESSING COMPLEX | METALLOPROTEINASE INHIBITOR | CLAUDIN-5 PROMOTER | DEMETHYLASE JMJD3 | ENDOCRINOLOGY & METABOLISM | OCCLUDIN | SPINAL-CORD-INJURY | TNF-ALPHA | HEMATOLOGY | NF-KAPPA-B | CEREBRAL-ISCHEMIA | Original
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 07/2010, Volume 10, Issue 7, pp. 457 - 469
Journal Article
Journal of Cell Biology, ISSN 0021-9525, 01/2018, Volume 217, Issue 1, pp. 65 - 77
Aging is the major risk factor for cancer, cardiovascular disease, diabetes, and neurodegenerative disorders. Although we are far from understanding the... 
LIFE-SPAN | SECRETORY PHENOTYPE | HEMATOPOIETIC STEM-CELLS | IN-VIVO | CHONDROCYTE SENESCENCE | INK4A/ARF EXPRESSION | CHRONIC INFLAMMATION | DNA-DAMAGE-RESPONSE | DEMETHYLASE JMJD3 CONTRIBUTES | CELLULAR SENESCENCE | CELL BIOLOGY | Reviews
Journal Article
International Journal of Biochemistry and Cell Biology, ISSN 1357-2725, 10/2015, Volume 67, pp. 148 - 157
Gene expression is epigenetically regulated through DNA methylation and covalent chromatin modifications, such as acetylation, phosphorylation, ubiquitination,... 
Jumonji | Utx | Jmjd3 | H3K27 | Histone demethylation | ENDODERM DIFFERENTIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | HISTONE DEMETHYLASE JMJD3 | MYELODYSPLASTIC SYNDROME | CELLULAR SENESCENCE | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | DOMAIN-CONTAINING PROTEINS | H3K27 DEMETHYLASE | GENE-EXPRESSION | ARGININE METHYLATION | MACROPHAGE POLARIZATION | Chromatin - metabolism | Polycomb Repressive Complex 2 - genetics | Epigenesis, Genetic | Humans | Jumonji Domain-Containing Histone Demethylases - immunology | Neurodegenerative Diseases - immunology | Histone Demethylases - genetics | Neoplasms - genetics | Gene Expression Regulation, Developmental | Polycomb Repressive Complex 2 - immunology | Lysine - metabolism | Germ Layers - growth & development | Germ Layers - cytology | Nuclear Proteins - genetics | Chromatin - chemistry | Neurodegenerative Diseases - pathology | Germ Layers - metabolism | Histone Demethylases - immunology | Neurodegenerative Diseases - genetics | Immunity, Innate | Nuclear Proteins - immunology | Jumonji Domain-Containing Histone Demethylases - genetics | Enhancer of Zeste Homolog 2 Protein | Animals | Histones - genetics | Neoplasms - immunology | Mice | Histones - metabolism | Neoplasms - pathology | Ubiquitin | Epigenetic inheritance | Nervous system diseases | Transferases | Histones | Methylation | Gene expression
Journal Article