X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (1163) 1163
jagged-1 protein (975) 975
serrate-jagged proteins (971) 971
animals (760) 760
humans (753) 753
membrane proteins - metabolism (562) 562
membrane proteins - genetics (525) 525
mice (494) 494
signal transduction (439) 439
intercellular signaling peptides and proteins - metabolism (434) 434
calcium-binding proteins - metabolism (430) 430
calcium-binding proteins - genetics (385) 385
intercellular signaling peptides and proteins - genetics (385) 385
female (347) 347
receptors, notch - metabolism (327) 327
expression (324) 324
intercellular signaling peptides and proteins (314) 314
notch (307) 307
male (299) 299
calcium-binding proteins (284) 284
ligands (260) 260
cell biology (252) 252
differentiation (211) 211
cells, cultured (180) 180
developmental biology (176) 176
jagged1 (176) 176
receptor, notch1 - metabolism (169) 169
activation (167) 167
gene expression (164) 164
oncology (160) 160
mutation (157) 157
biochemistry & molecular biology (155) 155
cell line, tumor (154) 154
receptors, notch (152) 152
receptors, notch - genetics (144) 144
signal transduction - physiology (141) 141
cell differentiation (140) 140
article (136) 136
mice, inbred c57bl (134) 134
cell proliferation (133) 133
immunohistochemistry (133) 133
intracellular signaling peptides and proteins (133) 133
jagged-1 protein - metabolism (130) 130
membrane proteins - physiology (126) 126
proteins (126) 126
gene expression regulation, developmental (124) 124
receptor, notch1 - genetics (124) 124
alagille syndrome - genetics (123) 123
gene (121) 121
phenotype (121) 121
analysis (120) 120
jagged-1 protein - genetics (119) 119
research (119) 119
drosophila (111) 111
stem cells (111) 111
cancer (110) 110
delta (109) 109
genetics & heredity (107) 107
pathway (106) 106
cells (105) 105
proteins - genetics (105) 105
apoptosis (104) 104
notch signaling (103) 103
rats (103) 103
adult (100) 100
middle aged (100) 100
signal transduction - drug effects (99) 99
cell line (98) 98
jagged-1 (96) 96
drosophila proteins (95) 95
reverse transcriptase polymerase chain reaction (95) 95
angiogenesis (93) 93
abridged index medicus (92) 92
genetic aspects (92) 92
alagille-syndrome (90) 90
membrane proteins (90) 90
notch protein (89) 89
hematology (86) 86
membrane proteins - biosynthesis (86) 86
stem-cells (85) 85
growth (84) 84
jag1 (84) 84
proliferation (84) 84
ligand (82) 82
signal transduction - genetics (82) 82
transcription factors (82) 82
transfection (80) 80
alagille syndrome (79) 79
genes (78) 78
mutations (78) 78
multidisciplinary sciences (77) 77
aged (76) 76
immunology (75) 75
progenitor cells (75) 75
gene-expression (74) 74
mice, knockout (74) 74
molecular sequence data (74) 74
receptor (73) 73
medicine, research & experimental (72) 72
research article (72) 72
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


The EMBO Journal, ISSN 0261-4189, 02/2011, Volume 30, Issue 4, pp. 770 - 782
Notch signalling is important for development and tissue homeostasis and activated in many human cancers. Nevertheless, mutations in Notch pathway components... 
miR‐200 | ZEB1 | EMT | Notch | stemness | miR-200 | STEM-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | PHENOTYPE | E-CADHERIN | MIR-200 FAMILY | REPRESSORS ZEB1 | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | BREAST-CANCER | COLORECTAL-CANCER | Receptors, Notch - metabolism | Humans | Receptors, Notch - genetics | Gene Knockdown Techniques | Intercellular Signaling Peptides and Proteins - physiology | DNA-Binding Proteins - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Neoplasms - genetics | Membrane Proteins - physiology | Serrate-Jagged Proteins | Base Sequence | Membrane Proteins - metabolism | Nuclear Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Transcription Factors - physiology | DNA-Binding Proteins - antagonists & inhibitors | Membrane Proteins - genetics | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | Nuclear Proteins - metabolism | Transcription Factors - antagonists & inhibitors | Signal Transduction - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Homeodomain Proteins - genetics | Transcription Factors - metabolism | Models, Biological | Calcium-Binding Proteins - physiology | Homeodomain Proteins - antagonists & inhibitors | Nuclear Proteins - antagonists & inhibitors | Signal Transduction - physiology | MicroRNAs - genetics | Feedback, Physiological - physiology | MicroRNAs - physiology | Homeodomain Proteins - physiology | Calcium-Binding Proteins - genetics | Zinc Finger E-box-Binding Homeobox 1 | Proteins | Signal transduction | Cellular biology | Molecular biology | Gene expression | Cancer | Index Medicus
Journal Article
Developmental Cell, ISSN 1534-5807, 03/2012, Volume 22, Issue 3, pp. 501 - 514
Gradients of vascular endothelial growth factor (VEGF) induce single endothelial cells to become leading tip cells of emerging angiogenic sprouts. Tip cells... 
DEFECTS | TIP CELLS | ANGIOGENESIS | VEGF | ENDOTHELIAL-CELLS | ID PROTEINS | HES1 | DEVELOPMENTAL BIOLOGY | DIFFERENTIATION | EXPRESSION | INHIBITS TUMOR-GROWTH | CELL BIOLOGY | Transcription Factor HES-1 | Humans | Intercellular Signaling Peptides and Proteins - biosynthesis | Intracellular Signaling Peptides and Proteins - metabolism | Inhibitor of Differentiation Proteins - biosynthesis | Inhibitor of Differentiation Protein 1 - biosynthesis | Serrate-Jagged Proteins | Smad5 Protein - metabolism | Basic Helix-Loop-Helix Transcription Factors - biosynthesis | Smad1 Protein - genetics | Membrane Proteins - metabolism | Smad5 Protein - genetics | Intracellular Signaling Peptides and Proteins - genetics | Jagged-1 Protein | Calcium-Binding Proteins - biosynthesis | Homeodomain Proteins - biosynthesis | Signal Transduction | Inhibitor of Differentiation Protein 2 - biosynthesis | Membrane Proteins - genetics | Down-Regulation | Cells, Cultured | Mice, Transgenic | Cell Cycle Proteins - biosynthesis | Vascular Endothelial Growth Factor Receptor-1 - biosynthesis | Mice, Knockout | Membrane Proteins - biosynthesis | Phenotype | Animals | Smad1 Protein - metabolism | Mice | Neovascularization, Physiologic | Proteins | Endothelial growth factors | Genes | Genetic aspects | Transforming growth factors | Vascular endothelial growth factor | Endothelium | Index Medicus | Dll4 | tip cell | lateral inhibition | sprouting angiogenesis | BMP | directed migration | Notch | stalk cell | mouse embryo | Smad | polarity
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2017, Volume 12, Issue 5, pp. e0177516 - e0177516
Myogenic stem cells are a promising avenue for the treatment of muscular disorders. Freshly isolated muscle stem cells have a remarkable engraftment ability in... 
PROGENITOR CELLS | SATELLITE CELL NICHE | MESENCHYMAL PROGENITORS | GENE | MYOD | MULTIDISCIPLINARY SCIENCES | EXPANSION | SELF-RENEWAL | DUCHENNE MUSCULAR-DYSTROPHY | HUMAN SKELETAL-MUSCLE | TRANSPLANTATION | Immunohistochemistry | Jagged-1 Protein - metabolism | MyoD Protein - genetics | Receptors, Notch - metabolism | PAX7 Transcription Factor - genetics | Receptors, Notch - genetics | Intracellular Signaling Peptides and Proteins - metabolism | PAX7 Transcription Factor - metabolism | Stem Cells - cytology | Stem Cells - metabolism | Cell Differentiation - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Myoblasts - metabolism | Regeneration - genetics | Myoblasts - cytology | Membrane Proteins - metabolism | Cell Differentiation - physiology | Intracellular Signaling Peptides and Proteins - genetics | Real-Time Polymerase Chain Reaction | Membrane Proteins - genetics | Muscle Development - physiology | Cells, Cultured | Intercellular Signaling Peptides and Proteins - genetics | MyoD Protein - metabolism | Signal Transduction - genetics | Regeneration - physiology | Jagged-1 Protein - genetics | Muscle Cells - cytology | Animals | Muscle Development - genetics | Signal Transduction - physiology | Mice | Transplantation | Research | Health aspects | Ligands (Biochemistry) | Analysis | Stem cells | Musculoskeletal diseases | Musculoskeletal system | Cell culture | MyoD protein | Allografts | Cell number | Stem cell transplantation | Ligands | Notch protein | Gene expression | Myoblasts | Index Medicus | Signal Transduction | Intercellular Signaling Peptides and Proteins | PAX7 Transcription Factor | Intracellular Signaling Peptides and Proteins | Cellular Biology | Stem Cells | Membrane Proteins | Life Sciences | Regeneration | Muscle Development | Receptors, Notch | Cell Differentiation | Muscle Cells | MyoD Protein | Jagged-1 Protein
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2013, Volume 110, Issue 5, pp. 1714 - 1719
Expression of the Notch ligand Jagged 1 (JAG1) and Notch activation promote poor-prognosis in breast cancer. We used high throughput screens to identify... 
Tumor cell line | Cell lines | Small interfering RNA | Breast cancer | Cells | Regulator genes | Genetic screening | Tumors | Mesenchymal stem cells | Cancer | EPITHELIAL-MESENCHYMAL TRANSITION | STEM-CELLS | IN-VITRO | ACTIVATED PROTEIN-KINASE | SIGNALING PATHWAY | TRIBBLES HOMOLOG | MULTIDISCIPLINARY SCIENCES | HYPOXIA | EXPRESSION | ESTROGEN-RECEPTOR | MAMMARY-GLAND | Humans | Breast Neoplasms - metabolism | MAP Kinase Signaling System | Intercellular Signaling Peptides and Proteins - metabolism | RNA Interference | Serrate-Jagged Proteins | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Cell Cycle Proteins - genetics | Female | Membrane Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Repressor Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Cell Line | Membrane Proteins - genetics | Cell Cycle Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Protein-Serine-Threonine Kinases - genetics | Repressor Proteins - genetics | Protein Kinase Inhibitors - isolation & purification | Receptor, Notch1 - metabolism | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Interleukin Receptor Common gamma Subunit - genetics | Blotting, Western | Hep G2 Cells | Mice, Knockout | Interleukin Receptor Common gamma Subunit - deficiency | Xenograft Model Antitumor Assays | Animals | Breast Neoplasms - genetics | Transforming Growth Factor beta - genetics | Signal Transduction - drug effects | Breast Neoplasms - pathology | Cell Line, Tumor | Mice, Inbred NOD | Mice | Protein Kinase Inhibitors - pharmacology | Receptor, Notch1 - genetics | Transforming Growth Factor beta - metabolism | Calcium-Binding Proteins - genetics | Index Medicus | Biological Sciences
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2013, Volume 8, Issue 4, pp. e60244 - e60244
Endocardial to mesenchymal transformation (EMT) is a fundamental cellular process required for heart valve formation. Notch, Wnt and Bmp pathways are known to... 
EPITHELIAL-MESENCHYMAL TRANSITION | TRANSFORMATION | DEVELOPING CHICKEN HEART | MORPHOGENESIS | CUSHION | CELLS | NF-ATC | MULTIDISCIPLINARY SCIENCES | GROWTH-FACTOR | TRANSCRIPTION FACTOR | CARDIAC DEVELOPMENT | Wnt4 Protein - metabolism | Embryo, Mammalian | Heart Valves - metabolism | Epithelial-Mesenchymal Transition - genetics | Endocardium - metabolism | Wnt4 Protein - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Gene Expression Regulation, Developmental | Serrate-Jagged Proteins | Bone Morphogenetic Protein 2 - metabolism | Myocardium - metabolism | Membrane Proteins - metabolism | Heart Valves - embryology | Extracellular Matrix Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Bone Morphogenetic Protein 2 - genetics | Signal Transduction | Endocardium - embryology | Membrane Proteins - genetics | Extracellular Matrix Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Mice, Transgenic | Receptor, Notch1 - metabolism | Animals | Organogenesis - genetics | Mice | Receptor, Notch1 - genetics | Calcium-Binding Proteins - genetics | Cellular signal transduction | Research | Wnt proteins | Heart valves | Heart | Transformation | Wnt protein | Mesenchyme | Laboratories | Paracrine signalling | Defects | Morphogenesis | Signal transduction | Cell growth | Pathways | Rodents | Bone morphogenetic proteins | Jagged1 protein | Cardiology | Immunoglobulins | Bone morphogenetic protein 2 | Cultures | Histology | Ribonucleic acid--RNA | Embryos | Medicine | Hospitals | Myocardium | Notch protein | Index Medicus | RNA | Ribonucleic acid
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2015, Volume 57, Issue 5, pp. 912 - 924
Mind bomb (Mib) proteins are large, multi-domain E3 ligases that promote ubiquitination of the cytoplasmic tails of Notch ligands. This ubiquitination step... 
SYSTEM | MORPHOGENESIS | PROTEIN | UBIQUITIN LIGASE | DELTA | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIFFERENTIATION | ENDOCYTOSIS | SERRATE | INTRACELLULAR MOTIFS | DROSOPHILA | CELL BIOLOGY | Wnt1 Protein | Epitopes - metabolism | Receptors, Notch - metabolism | Humans | Intercellular Signaling Peptides and Proteins - chemistry | Molecular Sequence Data | Crystallography, X-Ray | Receptors, Notch - genetics | Drosophila Proteins - metabolism | Drosophila melanogaster - genetics | Drosophila melanogaster - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Serrate-Jagged Proteins | HEK293 Cells | Membrane Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - chemistry | Calcium-Binding Proteins - metabolism | Protein Structure, Tertiary | Amino Acid Sequence | Protein Structure, Secondary | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Drosophila Proteins - chemistry | Epitopes - genetics | Ubiquitin-Protein Ligases - chemistry | Blotting, Western | Sequence Homology, Amino Acid | Animals | Membrane Proteins - chemistry | Receptors, Notch - chemistry | Cell Line, Tumor | Protein Binding | Ligands | Epitopes - chemistry | Drosophila Proteins - genetics | Mutation | Ubiquitin-Protein Ligases - genetics | Calcium-Binding Proteins - genetics | Ubiquitin | Cellular signal transduction | Ligases | Antigenic determinants | Structure | Crystals | Index Medicus | BASIC BIOLOGICAL SCIENCES
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2016, Volume 11, Issue 11, pp. e0166984 - e0166984
Birth defects are among the leading causes of infant mortality and contribute substantially to illness and long-term disability. Defects in Bone Morphogenetic... 
BRANCHIAL ARCH | DLX GENES | HEAD SKELETON | ALAGILLE-SYNDROME | DOWNS-SYNDROME | MULTIDISCIPLINARY SCIENCES | AURICULOCONDYLAR SYNDROME | LEFT-RIGHT ASYMMETRY | REPEAT PROTEIN | HUMAN JAGGED1 | NEURAL CREST CELLS | Jagged-1 Protein - metabolism | Zebrafish - embryology | Intercellular Signaling Peptides and Proteins - metabolism | Somites - embryology | Basic Helix-Loop-Helix Transcription Factors - metabolism | Nuclear Proteins - biosynthesis | Smad5 Protein - metabolism | Smad1 Protein - genetics | Smad5 Protein - genetics | Nuclear Proteins - genetics | Repressor Proteins - metabolism | Gene Expression Regulation, Developmental - physiology | Zebrafish Proteins - biosynthesis | Basic Helix-Loop-Helix Transcription Factors - genetics | Endothelin-1 - genetics | Endothelin-1 - metabolism | Zebrafish Proteins - metabolism | Intercellular Signaling Peptides and Proteins - genetics | Repressor Proteins - genetics | Jagged-1 Protein - genetics | Zebrafish - genetics | Body Patterning - physiology | Animals | Transforming Growth Factor beta - genetics | Facial Bones - enzymology | Smad1 Protein - metabolism | Signal Transduction - physiology | Zebrafish Proteins - genetics | Transforming Growth Factor beta - metabolism | Bone morphogenetic proteins | Genetic aspects | Research | Craniofacial abnormalities | Neural crest | Pattern formation | Jaw | Transcription factors | Endothelin | Arches | Congenital defects | Alagille syndrome | Genomics | Transforming growth factor-b | Genomes | Somites | Kinases | Defects | Proteins | Cartilage | Signal transduction | Pathways | Growth factors | Territory | Patterning | Mandible | Interference | Craniofacial syndromes | Zebrafish | Infant mortality | Birth defects | Endothelin 1 | Gene expression | Embryos | Mutants | Cleft lip/palate | Craniofacial growth | Signaling | Scaffolding | In vivo methods and tests | Notch protein | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 02/2013, Volume 23, Issue 2, pp. 171 - 185
We report a paracrine effect whereby endothelial cells (ECs) promote the cancer stem cell (CSC) phenotype of human colorectal cancer (CRC) cells. We showed... 
COLON-CANCER | METASTASIS | ONCOLOGY | NOTCH | NICHE | SELF-RENEWAL | RECEPTOR | GROWTH-FACTOR | TUMOR ANGIOGENESIS | DIFFERENTIATION | ANGIOCRINE FACTORS | CELL BIOLOGY | ADAM17 Protein | RNA, Small Interfering - genetics | Immunoprecipitation | Receptors, Notch - metabolism | Colorectal Neoplasms - genetics | Humans | Calcium-Binding Proteins - antagonists & inhibitors | Culture Media, Conditioned - pharmacology | Drug Resistance, Neoplasm | Immunoblotting | Peptide Fragments - pharmacology | Intercellular Signaling Peptides and Proteins - metabolism | Neoplastic Stem Cells - metabolism | Serrate-Jagged Proteins | Neoplastic Stem Cells - pathology | Antineoplastic Agents - pharmacology | Membrane Proteins - metabolism | Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization | Tumor Cells, Cultured | Liver Neoplasms - secondary | Colorectal Neoplasms - metabolism | Jagged-1 Protein | Biomarkers - metabolism | Calcium-Binding Proteins - metabolism | ADAM Proteins - antagonists & inhibitors | Liver Neoplasms - genetics | Signal Transduction | Endothelial Cells - metabolism | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Cell Communication | Xenograft Model Antitumor Assays | ADAM Proteins - metabolism | Phenotype | Animals | Membrane Proteins - antagonists & inhibitors | Mice, Nude | Liver Neoplasms - metabolism | Mice | ADAM Proteins - genetics | Colorectal Neoplasms - pathology | Endothelial Cells - pathology | Calcium-Binding Proteins - genetics | Genetic aspects | Colorectal cancer | Stem cells | Endothelium | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 03/2009, Volume 69, Issue 6, pp. 2400 - 2407
Despite rapid advances in many fronts, pancreatic cancer (PC) remains one of the most difficult human malignancies to treat due, in part, to de novo and... 
TARGET | STEM-CELLS | GROWTH INHIBITION | INVASION | TUMOR PROGRESSION | ONCOLOGY | PROSTATE-CANCER | TAMOXIFEN RESISTANCE | DOWN-REGULATION | E-CADHERIN | NF-KAPPA-B | RNA, Small Interfering - genetics | Pancreatic Neoplasms - metabolism | Receptors, Notch - metabolism | Humans | Deoxycytidine - pharmacology | Drug Resistance, Neoplasm | Intercellular Signaling Peptides and Proteins - biosynthesis | NF-kappa B - metabolism | Receptor, Notch2 - genetics | Receptors, Notch - genetics | Proto-Oncogene Proteins - biosynthesis | Cell Movement - physiology | Pancreatic Neoplasms - drug therapy | Intercellular Signaling Peptides and Proteins - metabolism | Transfection | Receptors, Notch - biosynthesis | Serrate-Jagged Proteins | Antimetabolites, Antineoplastic - pharmacology | Membrane Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Proto-Oncogene Proteins - metabolism | Calcium-Binding Proteins - biosynthesis | Signal Transduction | Membrane Proteins - genetics | Down-Regulation | Pancreatic Neoplasms - pathology | Intercellular Signaling Peptides and Proteins - genetics | Receptor, Notch2 - metabolism | Epithelial Cells - pathology | Pancreatic Neoplasms - genetics | Proto-Oncogene Proteins - genetics | Membrane Proteins - biosynthesis | Phenotype | Receptor, Notch2 - biosynthesis | Mesoderm - pathology | RNA, Messenger | Deoxycytidine - analogs & derivatives | Receptor, Notch4 | Calcium-Binding Proteins - genetics | Index Medicus
Journal Article
Stem Cells, ISSN 1549-4918, 2012, Volume 30, Issue 10, pp. 2320 - 2329
Adult neurogenesis is regulated by a number of cellular players within the neurogenic niche. Astrocytes participate actively in brain development, regulation... 
Vimentin | Astrocytes | Neurogenesis | Glial fibrillary acidic protein | Intermediate filaments | PROGENITOR CELLS | MOUSE-BRAIN | MICE DEFICIENT | ADULT HIPPOCAMPAL NEUROGENESIS | SUBVENTRICULAR ZONE | CELL & TISSUE ENGINEERING | CELL BIOLOGY | NEURAL STEM-CELLS | IN-VITRO | ONCOLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | FIBRILLARY ACIDIC PROTEIN | DENTATE GYRUS | HEMATOLOGY | INTERMEDIATE-FILAMENTS | Amyloid Precursor Protein Secretases - genetics | Receptors, Notch - metabolism | Coculture Techniques | Nerve Tissue Proteins - deficiency | Male | Receptors, Notch - genetics | Stem Cells - cytology | Vimentin - deficiency | Stem Cells - metabolism | Wnt Proteins - metabolism | Glial Fibrillary Acidic Protein | Neurogenesis - genetics | Intercellular Signaling Peptides and Proteins - metabolism | Endocytosis | Wnt Proteins - genetics | Gene Expression Regulation, Developmental | Serrate-Jagged Proteins | Vimentin - genetics | Cell Differentiation | Membrane Proteins - metabolism | Jagged-1 Protein | Astrocytes - cytology | Calcium-Binding Proteins - metabolism | Signal Transduction | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins - genetics | Cell Communication - genetics | Nerve Tissue Proteins - genetics | Mice, Knockout | Amyloid Precursor Protein Secretases - metabolism | Animals | Mice | Primary Cell Culture | Astrocytes - metabolism | Calcium-Binding Proteins - genetics | Neurosciences | Neurons | Analysis | Physiological aspects | Universities and colleges | Information management | Intermediate filament proteins | Ligands | Cells | Index Medicus | Basic Medicine | Medicinska grundvetenskaper | Neurovetenskaper
Journal Article
PLoS ONE, ISSN 1932-6203, 05/2014, Volume 9, Issue 5, pp. e96365 - e96365
Epithelial-mesenchymal transition (EMT) of retinal pigment epithelium (RPE) cells is a major pathologic change in the development of proliferative... 
FIBROSIS | PROLIFERATIVE VITREORETINAL DISEASES | ACTIVATION | TISSUE GROWTH-FACTOR | FACTOR-BETA | MULTIDISCIPLINARY SCIENCES | INVOLVEMENT | KINASE | SMAD | INHIBITOR | EXPRESSION | Epithelial Cells - metabolism | Gene Expression - drug effects | Nitriles - pharmacology | Receptors, Notch - metabolism | Epithelial Cells - drug effects | Humans | Mitogen-Activated Protein Kinase 3 - antagonists & inhibitors | Epithelial-Mesenchymal Transition - drug effects | Receptors, Notch - genetics | Smad3 Protein - metabolism | Intercellular Signaling Peptides and Proteins - metabolism | Multiprotein Complexes - metabolism | Serrate-Jagged Proteins | Dioxoles - pharmacology | Benzamides - pharmacology | Membrane Proteins - metabolism | Jagged-1 Protein | Calcium-Binding Proteins - metabolism | Cell Line | Butadienes - pharmacology | Membrane Proteins - genetics | Mitogen-Activated Protein Kinase 1 - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Intercellular Signaling Peptides and Proteins - genetics | Smad2 Protein - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Blotting, Western | Transforming Growth Factor beta2 - pharmacology | MAP Kinase Signaling System - drug effects | Mitogen-Activated Protein Kinase 3 - metabolism | Signal Transduction - drug effects | Receptor, Notch3 | Smad Proteins - metabolism | Retinal Pigment Epithelium - cytology | Calcium-Binding Proteins - genetics | Mitogen-Activated Protein Kinase 1 - metabolism | Smad protein | Mesenchyme | Laboratories | Transforming growth factor | Retina | Activation | Kinases | Carcinogenesis | Fibronectin | Retinal pigment epithelium | Metastases | Signal transduction | Carcinogens | N-Cadherin | Pathways | Breakdowns | Smad2 protein | Collagen (type IV) | Growth factors | Visually handicapped people | Immunoglobulins | Cytokines | Medical treatment | Extracellular signal-regulated kinase | Epithelium | Cadherin | Trauma | Signaling | Inhibitors | Fibrosis | Notch protein | Cancer | Index Medicus
Journal Article