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Cancer Letters, ISSN 0304-3835, 06/2016, Volume 375, Issue 2, pp. 209 - 220
Chronic intestinal inflammation is closely associated with colon cancer development and STAT3 seems to take center stage in bridging chronic inflammation to... 
CUL4A | Jak-STAT3 | Ubiquitination | Colon cancer | ligase complex | DICER1 | IL-6
Journal Article
Cell Metabolism, ISSN 1550-4131, 01/2018, Volume 27, Issue 1, pp. 136 - 150.e5
Cancer stem cells (CSCs) are critical for cancer progression and chemoresistance. How lipid metabolism regulates CSCs and chemoresistance remains elusive.... 
JAK/STAT3 | chemoresistance | fatty acid β-oxidation | leptin | breast cancer stem cell | ELECTRON-TRANSPORT CHAIN | MAINTENANCE | INHIBITION | THERAPY | METABOLISM | MEMORY | STAT3 | ENDOCRINOLOGY & METABOLISM | EXPRESSION | CD8(+) T-CELLS | TUMOR MICROENVIRONMENT | CELL BIOLOGY
Journal Article
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES, ISSN 1128-3602, 01/2018, Volume 22, Issue 2, pp. 551 - 560
OBJECTIVE: Esophageal cancer is the 8th most common cancers worldwide and the 6th most common cause of death among cancers. Curcumin has been reported to have... 
JAK/STAT3 | APOPTOSIS | OXIDATIVE STRESS | JAK/STAT3 PATHWAY | ADENOCARCINOMA | Cell adhesion | ROS | GROWTH | PHARMACOLOGY & PHARMACY | Curcumin | Cell adhesion molecules
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2018, Volume 22, Issue 7, pp. 1914 - 1921
Journal Article
Gene, ISSN 0378-1119, 08/2018, Volume 666, pp. 18 - 26
Colorectal cancer (CRC) is one of the most common malignant tumors and one of the leading causes of cancer-related death in both men and women. The prognosis... 
Proliferation | Metastasis | lnc-DILC | Colorectal cancer | STAT3 | GENETIC INSTABILITY | Inc-DILC | GENETICS & HEREDITY | STEM-CELL | IL-6/JAK/STAT3 PATHWAY | NETWORKS | STRATEGIES | RNA | Stem cells
Journal Article
Asian Pacific Journal of Cancer Prevention, ISSN 1513-7368, 2014, Volume 15, Issue 12, pp. 5071 - 5076
Cholangiocarcinoma (CCA) is one of the aggressive cancers with a very poor prognosis. Several efforts have been made to identify and develop new agents for... 
JAK/STAT3 | Luteolin | Migration | Cholangiocarcinoma | Cell cycle | Apoptosis | ONCOLOGY | cell cycle | GROWTH | KINASE | migration | apoptosis | SUPPRESSION | cholangiocarcinoma | CANCER | MODULATION
Journal Article
by Du, W and Wang, N and Li, F and Jia, KQ and An, JH and Liu, YP and Wang, YX and Zhu, L and Zhao, S and Hao, J
FASEB JOURNAL, ISSN 0892-6638, 07/2019, Volume 33, Issue 7, pp. 8008 - 8021
Schwann cells are the main supportive cells of the peripheral nerves. Schwann cells suffer inhibition of autophagy under hyperglycemia treatment in diabetic... 
Atg3 | JAK-STAT3 signaling | HDAC1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | JAK/STAT | P62 | histone deacetylase 1 | CELL BIOLOGY | PATHOGENESIS | INHIBITION | PATHWAY | BIOENERGETICS | BIOLOGY | LC3
Journal Article
World Chinese Journal of Digestology, ISSN 1009-3079, 2015, Volume 23, Issue 14, pp. 2228 - 2233
Journal Article
International Journal of Biological Macromolecules, ISSN 0141-8130, 10/2018, Volume 117, pp. 993 - 1001
Several studies have processed conceivable evidence for the vital role of Signal Transducer and Activator of Transcription 3 (STAT3) in cancer transformation... 
STAT3 | Apoptosis | Cancer | POLYMER SCIENCE | CONSTITUTIVE ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DEPENDENT APOPTOSIS | KAPPA-B | CELL-DEATH | MESSENGER-RNA | JAK/STAT3 PATHWAY | TRANSCRIPTION 3 STAT3 | SIGNALING PATHWAY | COLORECTAL-CANCER | ENDOTHELIAL-CELLS | CHEMISTRY, APPLIED | Index Medicus
Journal Article
Brain Research Bulletin, ISSN 0361-9230, 11/2019, Volume 153, pp. 191 - 201
•Propofol prevents oxidative stress and apoptosis of nerve cells.•Propofol inhibited apoptosis via regulating iron homeostasis.•Propofol can protect against... 
JAK/STAT3 signaling | Oxidative stress | Iron metabolism | Inflammation | Propofol | Apoptosis | ALZHEIMERS-DISEASE | HEPCIDIN | NEUROSCIENCES | METABOLISM | MICROGLIA | IN-VIVO | EXPRESSION
Journal Article
Cancer Letters, ISSN 0304-3835, 2016, Volume 375, Issue 2, pp. 209 - 220
Highlights • Inflammation-induced Jak-STAT3 signaling leads to colon cancer development through proteasomal degradation of DICER1 by ubiquitin ligase complex... 
Hematology, Oncology and Palliative Medicine | Jak-STAT3 | Ubiquitination | Colon cancer | DICER1 | CUL4ADCAF1 ligase complex | IL-6
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2020, Volume 522, Issue 1, pp. 81 - 87
Previous studies have shown that some inflammatory cytokines promote the expression of corticotropin-releasing hormone (CRH) in trophoblasts during pregnancy... 
Mouse trophoblast stem cell | JAK/STAT3 | MAPK | Corticotropin-releasing hormone | Leukemia inhibitory factor | PI3K/AKT | SIGNAL | BIOCHEMISTRY & MOLECULAR BIOLOGY | PLACENTA | PROLIFERATION | BIOPHYSICS | GENE | CRH | SECRETION | EXPRESSION
Journal Article
European Review for Medical and Pharmacological Sciences, ISSN 1128-3602, 2019, Volume 23, Issue 2, pp. 496 - 506
OBJECTIVE: Long intergenic non-protein coding RNA 518 (LINC00518) was reported to be implicated and aberrantly expressed in multiple cancers. However, the... 
JAK/STAT3 signaling | LncRNA | EMT | LINC00518 | Cervical cancer | INVASION | PATHWAY | PHARMACOLOGY & PHARMACY | CELL-PROLIFERATION
Journal Article
Clinical cancer research : an official journal of the American Association for Cancer Research, ISSN 1078-0432, 7/2015, Volume 21, Issue 14, pp. 3230 - 3240
Journal Article
OncoTargets and therapy, ISSN 1178-6930, 2019, Volume 12, pp. 5323 - 5334
Colorectal cancer (CRC) frequently metastasizes to the liver, which involves the participation of multiple cytokines. Tumor microenvironment (TME) composed of... 
JAK/STAT3 | Migration and invasion | TGFβ1 | MSCs-CAFs differentiation
Journal Article
Journal of Cellular Biochemistry, ISSN 0730-2312, 01/2020, Volume 121, Issue 1, pp. 735 - 742
Hepatocellular carcinoma (HCC) remains the most common malignant tumor worldwide. Long noncoding RNAs can modulate various tumorigenic processes. In addition,... 
JAK‐STAT3 pathway | hepatocellular carcinoma | LINC00346 | Cell proliferation | Wound healing | Cell survival | Transcription | Invasiveness | Stat3 protein | Hepatocellular carcinoma | Kinases | Liver cancer | Signal transduction | Cell cycle | Janus kinase | Tumors | Apoptosis | G1 phase
Journal Article
AGING-US, ISSN 1945-4589, 12/2019, Volume 11, Issue 24, pp. 11905 - 11921
Background/Aims: Kinesin family member 20A (KIF20A) is upregulated in multiple cancers and plays important roles in promoting malignant behavior, whereas its... 
CELLS | colorectal cancer | STAT3 | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | JAK/STAT3 | chemotherapy resistance | KINESIN | INHIBITION | malignant characteristics | KIF20A | PROTEINS | EXPRESSION
Journal Article
Journal Article
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