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Journal Article
Leukemia, ISSN 1476-5551, 05/2007, Volume 21, Issue 8, pp. 1658 - 1668
...) kinases, with significantly less activity against other tyrosine kinases including JAK3 (IC(50) = 169 nM... 
Oncology | Life Sciences & Biomedicine | Hematology | Science & Technology | fms-Like Tyrosine Kinase 3 - antagonists & inhibitors | Apoptosis - drug effects | Humans | STAT Transcription Factors - metabolism | Polycythemia Vera - genetics | Myeloproliferative Disorders - genetics | Janus Kinase 3 - antagonists & inhibitors | Polycythemia Vera - metabolism | fms-Like Tyrosine Kinase 3 - genetics | Janus Kinase 2 - metabolism | Myeloproliferative Disorders - metabolism | Colony-Forming Units Assay | Phosphorylation - drug effects | Janus Kinase 3 - metabolism | Janus Kinase 2 - antagonists & inhibitors | Primary Myelofibrosis - metabolism | Primary Myelofibrosis - drug therapy | Thrombopoietin - metabolism | Enzyme Inhibitors - pharmacology | Janus Kinase 2 - genetics | Myeloproliferative Disorders - drug therapy | Pyrimidines - pharmacology | Mice, SCID | Mutation - genetics | Sulfonamides - pharmacology | Receptors, Thrombopoietin - metabolism | Receptors, Thrombopoietin - antagonists & inhibitors | fms-Like Tyrosine Kinase 3 - metabolism | Receptors, Thrombopoietin - genetics | Primary Myelofibrosis - genetics | Animals | Janus Kinase 3 - genetics | Stem Cells - drug effects | Polycythemia Vera - drug therapy | Cell Proliferation - drug effects | Mice | Cell Cycle - drug effects | Antibody diversity | Chemical inhibitors | Genetic aspects | Research | Health aspects | Myeloproliferative disorders | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 05/2009, Volume 106, Issue 23, pp. 9414 - 9418
Journal Article
American journal of physiology: endocrinology and metabolism, ISSN 1522-1555, 08/2012, Volume 303, Issue 3, pp. E410 - E421
Cachexia, the metabolic dysregulation leading to sustained loss of muscle and adipose tissue, is a devastating complication of cancer and other chronic... 
Signal transducer and activator of transcription | Incb018424 | Electroporation | Inhibitory peptide | T cell protein tyrosine phosphatase/ protein tyrosine phosphatase | Janus-activated kinase | Interleukin-6 | Atrophy | Burn | Suppressors of cytokine signaling 3 | Lipopolysaccharide | Sepsis | Nonreceptor type 2 | Endocrinology & Metabolism | Physiology | Life Sciences & Biomedicine | Science & Technology | Neoplasms - metabolism | Wasting Syndrome - prevention & control | Wasting Syndrome - metabolism | Cricetulus | Male | Muscle, Skeletal - metabolism | Janus Kinases - metabolism | Neoplasms - complications | Neoplasms - genetics | Muscle, Skeletal - drug effects | Cachexia - etiology | Interleukin-6 - physiology | Female | Interleukin-6 - metabolism | STAT3 Transcription Factor - genetics | STAT3 Transcription Factor - metabolism | CHO Cells | Disease Models, Animal | Pyrazoles - pharmacology | Cricetinae | Cachexia - genetics | Interleukin-6 - genetics | Janus Kinases - genetics | Mice, Inbred C57BL | RNA, Small Interfering - pharmacology | Cells, Cultured | Mutant Proteins - genetics | Mice, Transgenic | Signal Transduction - genetics | Wasting Syndrome - genetics | Cachexia - prevention & control | Mutant Proteins - administration & dosage | Neoplasms - drug therapy | Janus Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Pyrazoles - administration & dosage | Animals | Signal Transduction - drug effects | Mice, Nude | Cachexia - pathology | Mice | Protein Kinase Inhibitors - pharmacology | Muscle, Skeletal - pathology | RNA, Small Interfering - administration & dosage | STAT3 Transcription Factor - antagonists & inhibitors | Wasting Syndrome - pathology | Transcription factors | Control | Analysis | Muscles | Genetic aspects | Wasting syndrome | Musculoskeletal system | Inhibitor drugs | Cytokines | Ligands | Metabolic disorders | Cancer | Index Medicus | incb018424 | protein tyrosine phosphatase, nonreceptor type 2 | burn | suppressors of cytokine signaling 3 | atrophy | signal transducer and activator of transcription 3 inhibitory peptide | electroporation | T cell protein tyrosine phosphatase | lipopolysaccharide | interleukin-6 | sepsis
Journal Article
Journal Article
PloS one, ISSN 1932-6203, 05/2015, Volume 10, Issue 5, pp. e0127942 - e0127942
...)-3, an intrinsic negative feedback regulator of the Janus kinase (JAK)-STAT signaling pathway, in the development of myocardial IRI... 
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Mitogen-Activated Protein Kinase 3 - genetics | Myeloid Cell Leukemia Sequence 1 Protein - metabolism | Suppressor of Cytokine Signaling Proteins - genetics | Myocardium - pathology | Myeloid Cell Leukemia Sequence 1 Protein - genetics | Proto-Oncogene Proteins c-akt - genetics | MAP Kinase Signaling System | Mice, Knockout | Muscle Proteins - genetics | Myocardial Reperfusion Injury - metabolism | Suppressor of Cytokine Signaling 3 Protein | Phosphorylation - genetics | Animals | Mitogen-Activated Protein Kinase 3 - metabolism | Gene Deletion | Myocardium - metabolism | Muscle Proteins - metabolism | Mice | Suppressor of Cytokine Signaling Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Myocardial Reperfusion Injury - genetics | Myocardial Reperfusion Injury - prevention & control | Prevention | Physiological aspects | Cellular signal transduction | Research | Cytokines | Reperfusion injury | Heart | Myocardial infarction | Phosphorylation | Bcl-2 protein | Transcription | Physicians | Leukemia | Myocardial ischemia | AKT protein | Activation | Kinases | Proteins | Signal transduction | Mitochondria | Negative feedback | Reperfusion | Ischemia | Clonal deletion | Rodents | Janus kinase | Heart diseases | Internal medicine | Coronary artery | Stat3 protein | Extracellular signal-regulated kinase | Cardiomyocytes | Mcl-1 protein | Medicine | Signaling | Injury prevention | Coronary vessels | Infarction | Apoptosis | Index Medicus
Journal Article
Journal Article
The Journal of immunology (1950), ISSN 1550-6606, 04/2011, Volume 186, Issue 7, pp. 4234 - 4243
Journal Article
Nature genetics, ISSN 1546-1718, 09/2011, Volume 43, Issue 10, pp. 932 - 939
Journal Article