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Journal Article
Nature Reviews Clinical Oncology, ISSN 1759-4774, 06/2015, Volume 12, Issue 6, pp. 319 - 334
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 05/2005, Volume 25, Issue 5, pp. 950 - 956
OBJECTIVE—Reactive oxygen species (ROS) integrate cellular signaling pathways involved in aortic smooth muscle cell (SMC) proliferation and migration... 
SMC | SOD | Thrombin | Cell signaling | ROS | OXIDATIVE STRESS | ATHEROGENESIS | thrombin | NITRIC-OXIDE SYNTHASE | TRANSDUCER | ANGIOTENSIN-II | HEAT-SHOCK | P47(PHOX) | cell signaling | PERIPHERAL VASCULAR DISEASE | DYSFUNCTION | HEMATOLOGY | OXIDANTS | MAP Kinase Signaling System - physiology | Superoxide Dismutase - genetics | Reactive Oxygen Species - metabolism | Protein-Tyrosine Kinases - metabolism | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Janus Kinase 2 | Mice, Mutant Strains | p38 Mitogen-Activated Protein Kinases - metabolism | Aorta - enzymology | STAT3 Transcription Factor - metabolism | Superoxide Dismutase - metabolism | Proto-Oncogene Proteins - metabolism | Proto-Oncogene Proteins - antagonists & inhibitors | Atherosclerosis - pathology | Mice, Inbred C57BL | Cells, Cultured | Enzyme Inhibitors - pharmacology | Atherosclerosis - metabolism | Cell Division - drug effects | Aorta - pathology | Cell Compartmentation - physiology | Cell Division - physiology | Gene Expression Regulation, Enzymologic | Muscle, Smooth, Vascular - pathology | Animals | MAP Kinase Signaling System - drug effects | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Mice | Superoxide Dismutase-1 | Muscle, Smooth, Vascular - enzymology | Hypertrophy | Protein-Tyrosine Kinases - antagonists & inhibitors
Journal Article
Drugs, ISSN 0012-6667, 4/2017, Volume 77, Issue 5, pp. 521 - 546
The Janus kinase/signal transduction and activator of transcription (JAK–STAT) signaling pathway is implicated in the pathogenesis of inflammatory and... 
Pharmacotherapy | Internal Medicine | Medicine & Public Health | Pharmacology/Toxicology | PHASE 2B TRIAL | VX-509 DECERNOTINIB | ALOPECIA-AREATA | MODIFYING ANTIRHEUMATIC DRUG | JANUS KINASE INHIBITOR | ACTIVE RHEUMATOID-ARTHRITIS | INADEQUATE RESPONSE | DOUBLE-BLIND | PHARMACOLOGY & PHARMACY | TOXICOLOGY | TOFACITINIB CP-690,550 | DRUG-DRUG INTERACTIONS | Janus Kinases - genetics | Humans | STAT Transcription Factors - metabolism | Janus Kinases - metabolism | Janus Kinases - antagonists & inhibitors | Protein Kinase Inhibitors - administration & dosage | Inflammation - metabolism | STAT Transcription Factors - genetics | Signal Transduction - drug effects | Inflammation - drug therapy | Protein Kinase Inhibitors - therapeutic use | Protein Kinase Inhibitors - pharmacology | STAT Transcription Factors - antagonists & inhibitors | Autoimmune Diseases - metabolism | Autoimmune Diseases - drug therapy | Dosage and administration | Tofacitinib | Autoimmune diseases | Drug therapy | Regulatory agencies | Inflammatory bowel diseases | Phosphorylation | Transcription factors | Disease | Transcription | Pathogenesis | Genes | Disorders | Clinical trials | Intracellular signalling | Arthritis | Kinases | Inflammatory diseases | Signal transduction | Intestine | Rodents | Janus kinase | Tumor necrosis factor-TNF | Medical research | Cytokines | Psoriasis | Baldness | Immunodeficiency | Patients | Diseases | Reviews | Rheumatoid arthritis | Transduction | Intracellular | Mutation
Journal Article
Annals of the Rheumatic Diseases, ISSN 0003-4967, 06/2017, Volume 76, Issue 6, pp. 960 - 977
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 09/2014, Volume 371, Issue 11, pp. 1005 - 1015
About 25% of young adults with ALL have Ph-like genotypes, which are associated with poor outcomes with conventional treatment. In this gene-expression study,... 
MEDICINE, GENERAL & INTERNAL | MODELS | B-CELL PRECURSOR | INHIBITOR THERAPY | IMATINIB | PEDIATRIC ACUTE LEUKEMIAS | GENE FUSION | EXPRESSION | ETV6-NTRK3 FUSION TRANSCRIPTS | CRLF2 | DELETION | Oligonucleotide Array Sequence Analysis | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - metabolism | Humans | Child, Preschool | Infant | Male | Young Adult | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - drug therapy | Heterografts | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - mortality | Adult | Female | DNA, Neoplasm - analysis | Receptors, Cytokine - metabolism | Child | Philadelphia Chromosome | Receptors, Cytokine - genetics | Signal Transduction - genetics | Precursor B-Cell Lymphoblastic Leukemia-Lymphoma - genetics | Animals | Protein Kinase Inhibitors - therapeutic use | Adolescent | Survival Analysis | Mice | Polymorphism, Single Nucleotide | Genome, Human | Protein-Tyrosine Kinases - antagonists & inhibitors | Development and progression | Care and treatment | Genetic aspects | Research | Lymphocytic leukemia | Tyrosine metabolism | Cell proliferation | Adolescence | Tyk2 protein | Leukemia | Genes | Clinical trials | Oncology | Genomes | Kinases | Cell activation | Janus kinase 2 | Xenografts | Teenagers | Children | Protein-tyrosine kinase | Age | Tyrosine | Young adults | Genomic analysis | Acute lymphatic leukemia | Stat5 protein | Lymphatic leukemia | Gene expression | Philadelphia chromosome | Interleukin 7 receptors | Thymic stromal lymphopoietin | Lymphocytes B | Cell lines
Journal Article