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Medicine (United States), ISSN 0025-7974, 07/2012, Volume 91, Issue 4, pp. e1 - e19
Autosomal dominant deficiency of signal transducer and activator of transcription 3 (STAT3) is the main genetic etiology of hyper-immunoglobulin (Ig) E... 
MEDICINE, GENERAL & INTERNAL | JOBS-SYNDROME | TRANSCRIPTION 3 | HYPERIMMUNOGLOBULIN-E SYNDROME | INVASIVE FUNGAL DISEASE | RECURRENT INFECTION | ANTIBODY-RESPONSES | CHRONIC MUCOCUTANEOUS CANDIDIASIS | COLD STAPHYLOCOCCAL ABSCESSES | SIGNAL TRANSDUCER | BONE-RESORPTION | Job Syndrome - immunology | Phosphorylation | Age Distribution | Job Syndrome - genetics | Humans | Middle Aged | Pneumonia, Bacterial - etiology | Child, Preschool | Infant | Male | Incidence | Skin Diseases, Bacterial - etiology | Young Adult | Eczema - epidemiology | Skin Diseases, Bacterial - epidemiology | DNA Mutational Analysis | STAT3 Transcription Factor - deficiency | Adult | Female | Respiratory Tract Infections - etiology | Genetic Predisposition to Disease - epidemiology | Child | Infant, Newborn | STAT3 Transcription Factor - genetics | Databases, Factual | Severity of Illness Index | France - epidemiology | Cross-Sectional Studies | Risk Assessment | Signal Transduction | Pneumonia, Bacterial - epidemiology | Eczema - etiology | Job Syndrome - epidemiology | Staphylococcal Infections - epidemiology | Job Syndrome - complications | Adolescent | Immunocompromised Host - genetics | Survival Analysis | Sex Distribution | Heterozygote | Respiratory Tract Infections - epidemiology | Staphylococcal Infections - etiology | Gene mutations | Causes of | Physiological aspects | Immunological deficiency syndromes | ACHOO syndrome | Genetic aspects | Research | Genetic transcription | T cells | Index Medicus | Abridged Index Medicus | Life Sciences | Genetics | Immunology
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2009, Volume 124, Issue 6, pp. 1289 - 1302.e4
Journal Article
The New England Journal of Medicine, ISSN 0028-4793, 10/2007, Volume 357, Issue 16, pp. 1608 - 1619
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 5, pp. 1410 - 1419.e13
Background Recurrent bacterial and fungal infections, eczema, and increased serum IgE levels characterize patients with the hyper-IgE syndrome (HIES). Known... 
Allergy and Immunology | glycosylation | Hyper-IgE syndrome | signal transducer and activator of transcription 3 | phosphoglucomutase 3 | Staphylococcus aureus | dedicator of cytokinesis 8 | INFECTIONS | DOCK8 | PRIMARY IMMUNODEFICIENCIES | IMMUNOLOGY | IDENTIFICATION | DEFICIENCY | ALLERGY | DISEASE | CONGENITAL DISORDERS | LINKAGE ANALYSIS | MUTASE | Job Syndrome - immunology | Cell Proliferation | Job Syndrome - genetics | T-Lymphocytes - enzymology | Humans | Genetic Diseases, Inborn - genetics | Immunoglobulin E | Infant | Male | Mutation, Missense | Job Syndrome - enzymology | Adult | Female | Child | Tunisia | Genetic Linkage | Phosphoglucomutase - metabolism | Genetic Diseases, Inborn - immunology | Glycosylation | Chromosomes, Human, Pair 6 - genetics | Homozygote | Chromosomes, Human, Pair 6 - metabolism | Genetic Diseases, Inborn - enzymology | T-Lymphocytes - immunology | Phosphoglucomutase - immunology | Immunity - genetics | Phosphoglucomutase - genetics | Amino Acid Substitution | Enzymes | Polysaccharides | Molecular genetics | Stem cells | Physiological aspects | Mycoses | Genetic aspects | Cellular signal transduction | Disease susceptibility | Genetic transcription | Proteins | Signal transduction | Cell growth | Polypeptides | Disease | Values | Mutation | Tetanus | Kinases | Chromosomes | Index Medicus | Abridged Index Medicus | T-Lymphocytes | Genetic Diseases, Inborn | Chromosomes, Human, Pair 6 | Immunity | Phosphoglucomutase | Life Sciences | Immunology | Job Syndrome | PGM3 | STAT3 | Basic Medicine | Medical and Health Sciences | Medicin och hälsovetenskap | Medicinska och farmaceutiska grundvetenskaper | Immunologi inom det medicinska området | Immunology in the medical area
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 136, Issue 2, pp. 402 - 412
Background Mutations in dedicator of cytokinesis 8 (DOCK8) cause a combined immunodeficiency (CID) also classified as autosomal recessive (AR) hyper-IgE... 
Allergy and Immunology | Primary combined immunodeficiency | autosomal recessive hyper-IgE syndrome | signal transducer and activator of transcription 3 | Molluscum contagiosum | hyper-IgE syndrome | dedicator of cytokinesis 8 | SURVIVAL | BONE-MARROW-TRANSPLANTATION | STAT3 | GLYCOSYLATION | IMMUNOLOGY | ALLERGY | DOCK8 DEFICIENCY | DISORDER | MUTATIONS | STEM-CELL TRANSPLANTATION | IMMUNODEFICIENCY | Job Syndrome - genetics | Job Syndrome - mortality | Humans | Middle Aged | Child, Preschool | Male | Support Vector Machine | Virus Diseases - complications | Eosinophils - immunology | Immunoglobulin E - blood | CD4-Positive T-Lymphocytes - immunology | Bacterial Infections - genetics | Eosinophils - pathology | Virus Diseases - genetics | Child | Guanine Nucleotide Exchange Factors - deficiency | STAT3 Transcription Factor - genetics | Skin Diseases - mortality | Immunoglobulin M - genetics | Guanine Nucleotide Exchange Factors - genetics | Virus Diseases - immunology | Skin Diseases - immunology | Antigens, Viral - immunology | Phenotype | Skin Diseases - complications | Job Syndrome - complications | Adolescent | Survival Analysis | Virus Diseases - mortality | Mutation | STAT3 Transcription Factor - immunology | CD8-Positive T-Lymphocytes - immunology | Bacterial Infections - mortality | Job Syndrome - immunology | CD8-Positive T-Lymphocytes - pathology | Skin Diseases - genetics | Antigens, Bacterial - immunology | Infant | Antigens, Bacterial - blood | CD4-Positive T-Lymphocytes - pathology | Antigens, Viral - blood | Bacterial Infections - complications | Immunoglobulin E - genetics | Bacterial Infections - immunology | Adult | Female | Immunoglobulin M - blood | Guanine Nucleotide Exchange Factors - immunology | Lymphocyte Count | Genotype & phenotype | Immunoglobulins | Laboratories | Lymphocytes | Families & family life | Lymphomas | Viral infections | Deoxyribonucleic acid--DNA | Index Medicus | Abridged Index Medicus | Immunoglobulin M | Immunoglobulin E | CD8-Positive T-Lymphocytes | Life Sciences | Antigens, Viral | Bacterial Infections | Job Syndrome | CD4-Positive T-Lymphocytes | Virus Diseases | Skin Diseases | Antigens, Bacterial | Guanine Nucleotide Exchange Factors | STAT3 Transcription Factor | Eosinophils
Journal Article
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 04/2018, Volume 141, Issue 4, pp. 1450 - 1458
Combined immunodeficiencies (CIDs) are diseases of defective adaptive immunity with diverse clinical phenotypes. Although CIDs are more prevalent in the Middle... 
next-generation DNA sequencing | targeted gene panel sequencing | Combined immunodeficiencies | whole-exome sequencing | UNITED-STATES | COMMON VARIABLE IMMUNODEFICIENCY | DISORDERS | IMMUNOLOGY | CENTERS | DISEASES | IRAN | ALLERGY | MOLECULAR DIAGNOSIS | UPDATE | T-CELLS | REGISTRY | Job Syndrome - immunology | Job Syndrome - genetics | Genes, Recessive - genetics | Job Syndrome - mortality | Humans | Child, Preschool | Infant | Male | Mutation - immunology | Iran | Immunologic Deficiency Syndromes - mortality | Female | Retrospective Studies | High-Throughput Nucleotide Sequencing - methods | Immunologic Deficiency Syndromes - immunology | Child | STAT3 Transcription Factor - genetics | Genetic Predisposition to Disease - genetics | Survival Rate | Mutation - genetics | Phenotype | Adolescent | Immunologic Deficiency Syndromes - genetics | Consanguinity | STAT3 Transcription Factor - immunology | Sequence Analysis, DNA - methods | Genes, Recessive - immunology | Genetic research | Immunodeficiency | Transcription | Laboratories | Genes | Immunoglobulin E | DNA repair | Immunity | Genetic screening | Defects | Gene sequencing | Ataxia | Diagnosis | Job's syndrome | Age | Deoxyribonucleic acid--DNA | Mortality | V(D)J recombination | Stat3 protein | Data processing | Adaptive immunity | Patients | Ataxia telangiectasia | Ataxia telangiectasia mutated protein | Diagnostic systems | Mutation | DNA sequencing
Journal Article
Nature Genetics, ISSN 1061-4036, 2014, Volume 46, Issue 8, pp. 812 - 814
Journal Article
Journal of clinical immunology, ISSN 0271-9142, 2015, Volume 35, Issue 2, pp. 189 - 198
Journal Article