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Nature Reviews Immunology, ISSN 1474-1733, 10/2011, Volume 11, Issue 10, pp. 658 - 671
Journal Article
Blood, ISSN 0006-4971, 05/2007, Volume 109, Issue 9, pp. 3794 - 3802
IL-17 and its receptor are founding members of a novel family of inflammatory cytokines. IL-17 plays a pathogenic role in rheumatoid arthritis (RA)-associated... 
RHEUMATOID-ARTHRITIS | ALVEOLAR BONE | COLONY-STIMULATING FACTOR | T-CELL INTERLEUKIN-17 | PORPHYROMONAS-GINGIVALIS | HOST-DEFENSE | JOINT DESTRUCTION | IL-17-DEFICIENT MICE | PERIODONTAL-DISEASE | HEMATOLOGY | KLEBSIELLA-PNEUMONIAE | Leukopoiesis - genetics | Osteitis - genetics | Humans | Receptors, Interleukin - deficiency | Bacteroidaceae Infections - genetics | Interleukin-17 - immunology | Pulmonary Disease, Chronic Obstructive - pathology | Receptors, Interleukin-8B - deficiency | Signal Transduction - immunology | Coronary Artery Disease - pathology | Porphyromonas gingivalis - immunology | Osteolysis - pathology | Bacteroidaceae Infections - pathology | Chemokines - immunology | Neutrophil Infiltration - immunology | Neutrophils - pathology | Pulmonary Disease, Chronic Obstructive - genetics | Periodontitis - immunology | Leukopoiesis - immunology | Receptors, Interleukin - immunology | Osteolysis - genetics | Neutrophils - immunology | Osteolysis - immunology | Periodontitis - pathology | Receptors, Interleukin-8B - immunology | Signal Transduction - genetics | Periodontitis - genetics | Neutrophil Infiltration - genetics | Mice, Knockout | Animals | Osteitis - immunology | Bacteroidaceae Infections - immunology | Osteitis - pathology | Coronary Artery Disease - genetics | Mice | Coronary Artery Disease - immunology | Pulmonary Disease, Chronic Obstructive - immunology | Immunobiology
Journal Article
Biochemical and biophysical research communications, ISSN 0006-291X, 09/2017, Volume 490, Issue 4, pp. 1274 - 1281
Enhanced turnover of subchondral trabecular bone is a hallmark of rheumatoid arthritis (RA) and it results from an imbalance between bone resorption and bone... 
Autoimmunity | Phosphotransferases (Alcohol Group Acceptor) - immunology | Temporomandibular Joint - pathology | rac1 GTP-Binding Protein - immunology | Mice, Inbred MRL lpr | Arthritis, Rheumatoid - drug therapy | Bone Resorption - genetics | Bone Marrow Cells - immunology | fas Receptor - genetics | Cell Differentiation | Mitogen-Activated Protein Kinases - immunology | Disease Models, Animal | NF-kappa B - antagonists & inhibitors | Osteoclasts - pathology | Macrophages - pathology | Signal Transduction | Bone Marrow Cells - pathology | Bone Resorption - immunology | Temporomandibular Joint - drug effects | Arthritis, Rheumatoid - genetics | Sphingosine - analogs & derivatives | Proto-Oncogene Proteins c-akt - immunology | Bone Resorption - pathology | Temporomandibular Joint - immunology | Mitogen-Activated Protein Kinases - genetics | Mice | Neuropeptides - immunology | NF-kappa B - immunology | Osteogenesis - immunology | Lysophospholipids - immunology | Proto-Oncogene Proteins c-akt - genetics | RANK Ligand - immunology | fas Receptor - immunology | Osteoclasts - immunology | Receptors, Lysosphingolipid - genetics | Bone Marrow Cells - drug effects | Female | Neuropeptides - genetics | Macrophages - immunology | Osteogenesis - drug effects | Gene Expression Regulation | Phosphotransferases (Alcohol Group Acceptor) - genetics | Sphingosine - immunology | Arthritis, Rheumatoid - pathology | Peptides - pharmacology | Bone Resorption - prevention & control | RANK Ligand - genetics | Receptors, Lysosphingolipid - immunology | Animals | NF-kappa B - genetics | Macrophages - drug effects | Primary Cell Culture | Arthritis, Rheumatoid - immunology | Osteoclasts - drug effects | rac1 GTP-Binding Protein - genetics
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2015, Volume 194, Issue 6, pp. 2810 - 2818
Macrophages play a major role in joint inflammation. Estrogen is involved in rheumatoid arthritis and temporomandibular disorders. However, the underlying... 
RHEUMATOID-ARTHRITIS | PATHOGENESIS | PAIN | ENDOMETRIAL STROMAL CELLS | TISSUE | KAPPA-B | IMMUNOLOGY | OVARIECTOMIZED RATS | EXPRESSION | ALTERNATIVE ACTIVATION | DISEASE-ACTIVITY | Estradiol - analogs & derivatives | Receptors, Estrogen - metabolism | Estrogens - pharmacology | Arthritis - metabolism | Cadherins - metabolism | Gene Expression - drug effects | Arginase - metabolism | Arthritis - genetics | Temporomandibular Joint - pathology | Receptors, Estrogen - immunology | Estrogen Receptor Antagonists - pharmacology | Arginase - immunology | Inflammation - metabolism | Cadherins - immunology | Nitric Oxide Synthase Type II - immunology | Gene Expression - immunology | Tumor Necrosis Factor-alpha - immunology | Arthritis - immunology | Interleukin-10 - metabolism | Female | Cadherins - genetics | Estradiol - pharmacology | Macrophages - immunology | Nitric Oxide - immunology | Ovariectomy | Macrophage Activation - immunology | Receptors, Estrogen - antagonists & inhibitors | Arginase - genetics | Inflammation - immunology | Reverse Transcriptase Polymerase Chain Reaction | Rats, Sprague-Dawley | Blotting, Western | Estradiol - immunology | Temporomandibular Joint - drug effects | Microscopy, Confocal | Tumor Necrosis Factor-alpha - pharmacology | Macrophages - metabolism | Animals | Nitric Oxide Synthase Type II - genetics | Interleukin-10 - genetics | Temporomandibular Joint - immunology | Inflammation - genetics | Estrogens - immunology | Macrophages - drug effects | Macrophage Activation - drug effects | Nitric Oxide - metabolism | Interleukin-10 - immunology | Nitric Oxide Synthase Type II - metabolism
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 11/2012, Volume 109, Issue 46, pp. 18647 - 18648
Neutrophil recruitment into the joint is a hallmark of inflammatory arthritides, including rheumatoid arthritis (RA). In a mouse model of autoantibody-induced... 
PNAS PLUS (AUTHOR SUMMARIES) | IMMUNE-COMPLEX ARTHRITIS | STERILE INFLAMMATION | RHEUMATOID SYNOVIAL-FLUIDS | BONE-MARROW-TRANSPLANTATION | MULTIDISCIPLINARY SCIENCES | AUTOANTIBODY-MEDIATED ARTHRITIS | MAST-CELLS | INFL AMMATORY ARTHRITIS | GENE-EXPRESSION | INFLAMMATORY ARTHRITIS | SERUM-INDUCED ARTHRITIS | Receptor, Anaphylatoxin C5a - genetics | Arthritis, Experimental - genetics | Receptors, Leukotriene B4 - genetics | Interleukin-1beta - genetics | Arthritis, Experimental - pathology | Autoantibodies - pharmacology | Signal Transduction - immunology | Receptors, IgG - genetics | Arthritis, Experimental - chemically induced | Receptor, Anaphylatoxin C5a - immunology | Receptors, CCR1 - immunology | Chemokines - immunology | Neutrophil Infiltration - immunology | Neutrophils - pathology | Neutrophils - immunology | Interleukin-1beta - immunology | Joints - pathology | Arthritis, Experimental - immunology | Receptors, Interleukin-8B - immunology | Signal Transduction - genetics | Receptors, IgG - immunology | Leukotriene B4 - immunology | Chemokines - genetics | Neutrophil Infiltration - genetics | Receptors, Leukotriene B4 - immunology | Mice, Knockout | Receptors, CCR1 - genetics | Animals | Joints - immunology | Receptors, Interleukin-8B - genetics | Complement C5a - genetics | Mice | Complement C5a - immunology | Leukotriene B4 - genetics | Autoantibodies - adverse effects | PNAS Plus | Biological Sciences
Journal Article
Journal Article
Journal Article
Journal of Immunology, ISSN 0022-1767, 07/2015, Volume 195, Issue 2, pp. 528 - 540
Journal Article
Journal of Autoimmunity, ISSN 0896-8411, 2012, Volume 39, Issue 3, pp. 222 - 228
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2015, Volume 194, Issue 6, pp. 2487 - 2492
Journal Article
International Immunology, ISSN 0953-8178, 11/2011, Volume 23, Issue 11, pp. 701 - 712
Rheumatoid arthritis (RA) is a chronic inflammatory disease that causes irreversible joint damage and significant disability. However, the fundamental... 
Joint destruction | Chronic inflammation | Collagen-induced arthritis | Rheumatoid arthritis | IL-6 | RHEUMATOID-ARTHRITIS | INTERLEUKIN-1 RECEPTOR ANTAGONIST | STAT3 | MONOCLONAL-ANTIBODY | IMMUNOLOGY | rheumatoid arthritis | OSTEOCLASTOGENESIS | RODENT MODELS | TUMOR-NECROSIS-FACTOR | collagen-induced arthritis | REGULATORY T-CELLS | DOUBLE-BLIND | joint destruction | NF-KAPPA-B | chronic inflammation | Tumor Necrosis Factor-alpha - metabolism | Inflammation - pathology | Arthritis, Experimental - drug therapy | RANK Ligand - metabolism | Humans | Arthritis, Rheumatoid - complications | Interleukin-1beta - adverse effects | Arthritis, Experimental - pathology | RANK Ligand - immunology | Inflammation - complications | Signal Transduction - immunology | Osteoclasts - immunology | Arthritis, Rheumatoid - drug therapy | Inflammation - drug therapy | Interleukin-1beta - metabolism | Piperidines | Gene Expression - immunology | STAT3 Transcription Factor - deficiency | Tumor Necrosis Factor-alpha - immunology | Mice, Inbred DBA | Pyrroles - therapeutic use | Interleukin-6 - metabolism | Joints - metabolism | STAT3 Transcription Factor - genetics | Joints - drug effects | Mice, Inbred C57BL | Enzyme Inhibitors - pharmacology | Interleukin-1beta - immunology | Joints - pathology | Arthritis, Experimental - immunology | Inflammation - immunology | Pyrimidines - pharmacology | Arthritis, Rheumatoid - pathology | Pyrroles - pharmacology | Animals | Tumor Necrosis Factor-alpha - adverse effects | Interleukin-6 - pharmacology | RANK Ligand - antagonists & inhibitors | Pyrimidines - therapeutic use | Fibroblasts - drug effects | Interleukin-6 - immunology | Fibroblasts - immunology | Mice | STAT3 Transcription Factor - immunology | Arthritis, Rheumatoid - immunology | STAT3 Transcription Factor - antagonists & inhibitors | Chronic Disease | Osteoclasts - drug effects | Animal models | Transcription | Leukemia inhibitory factor | Stat3 protein | Data processing | Inflammation | Joint diseases | Osteoblasts | Inflammatory diseases | Interleukin 6 | Osteoclastogenesis | Collagen | Interleukin 1 | TRANCE protein | Tumor necrosis factor- alpha
Journal Article