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humans (890) 890
jumonji domain-containing histone demethylases - metabolism (871) 871
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Nature (London), ISSN 1476-4687, 2014, Volume 514, Issue 7523, pp. 513 - 517
Journal Article
EMBO reports, ISSN 1469-3178, 2011, Volume 12, Issue 5, pp. 463 - 469
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 488, Issue 7411, pp. 404 - 408
Journal Article
Journal of the American Chemical Society, ISSN 0002-7863, 06/2011, Volume 133, Issue 24, pp. 9451 - 9456
Journal Article
Nature (London), ISSN 1476-4687, 2012, Volume 483, Issue 7390, pp. 474 - 478
...). Here we report that 2HG-producing IDH mutants can prevent the histone demethylation that is required for lineage-specific progenitor cells to differentiate into terminally differentiated cells... 
GENE | SETDB1 | DNA | MULTIDISCIPLINARY SCIENCES | INTEGRATED GENOMIC ANALYSIS | TRANSCRIPTION | LEUKEMIA | ONCOMETABOLITE 2-HYDROXYGLUTARATE | TUMORS | BRAIN | Humans | Adipocytes - cytology | Adipocytes - drug effects | Isocitrate Dehydrogenase - antagonists & inhibitors | Promoter Regions, Genetic - genetics | Glioma - genetics | Cell Differentiation - genetics | Glioma - pathology | Jumonji Domain-Containing Histone Demethylases - antagonists & inhibitors | HEK293 Cells | Enzyme Induction - drug effects | Cell Lineage - genetics | Astrocytes - cytology | Astrocytes - drug effects | Glioma - enzymology | Jumonji Domain-Containing Histone Demethylases - deficiency | Isocitrate Dehydrogenase - genetics | 3T3-L1 Cells | Mutation - genetics | Jumonji Domain-Containing Histone Demethylases - genetics | Gene Expression Regulation - drug effects | Animals | Methylation - drug effects | Cell Differentiation - drug effects | Adipocytes - metabolism | Cell Line, Tumor | Isocitrate Dehydrogenase - metabolism | Glutarates - metabolism | Mice | Glutarates - pharmacology | Histones - metabolism | DNA Methylation - drug effects | Jumonji Domain-Containing Histone Demethylases - metabolism | Neural Stem Cells - metabolism | DNA methylation | Genetics | Statistical analysis | Mutation | Brain cancer
Journal Article
Journal of medicinal chemistry, ISSN 0022-2623, 02/2016, Volume 59, Issue 4, pp. 1388 - 1409
Journal Article
Journal Article
11.