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Publication DateProtein engineering, design and selection, ISSN 1741-0126, 05/2017, Volume 30, Issue 5, pp. 395 - 399
) | k | desensitize to competitive inhibition | directed evolution | Plant Proteins - genetics | Zea mays - genetics | Models, Chemical | Plant Proteins - chemistry | Bacterial Proteins - chemistry | Bacterial Proteins - genetics | Klebsiella pneumoniae - enzymology | Klebsiella pneumoniae - genetics | Zea mays - enzymology | Directed Molecular Evolution | Kinetics | Index Medicus
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Loading RightsAnaerobe, ISSN 1075-9964, 12/2013, Volume 24, pp. 43 - 48
Kcat | Lactate dehydrogenase | Km | RMSD | Biofilm units | Vmax | K | V | Life Sciences & Biomedicine | Microbiology | Science & Technology | L-Lactate Dehydrogenase - metabolism | Staphylococcus aureus - enzymology | Molecular Weight | Humans | Molecular Sequence Data | DNA, Bacterial - chemistry | Recombinant Proteins - isolation & purification | L-Lactate Dehydrogenase - chemistry | Cloning, Molecular | Conserved Sequence | Pyruvic Acid - metabolism | Recombinant Proteins - metabolism | Staphylococcus aureus - genetics | Gene Expression | Lactic Acid - metabolism | Recombinant Proteins - chemistry | L-Lactate Dehydrogenase - isolation & purification | Recombinant Proteins - genetics | Sequence Analysis, DNA | Amino Acid Motifs | DNA, Bacterial - genetics | L-Lactate Dehydrogenase - genetics | Escherichia coli - genetics | Molecular Docking Simulation | Kinetics | Enzymes | Zoology | Cloning | Genes | Genetic research | Genetic aspects | Glucose | Bacterial genetics | Dextrose | Staphylococcus aureus | Index Medicus
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Loading RightsOncogene, ISSN 0950-9232, 08/2015, Volume 34, Issue 32, pp. 4248 - 4259
Biochemistry & Molecular Biology | Oncology | Genetics & Heredity | Life Sciences & Biomedicine | Science & Technology | Cell Biology | RNA, Small Interfering - genetics | ras Proteins - genetics | Proto-Oncogene Proteins p21(ras) | Epithelial Cells - metabolism | Cadherins - metabolism | Vimentin - metabolism | Humans | Gene Expression Regulation, Neoplastic | ras Proteins - metabolism | Transplantation, Heterologous | Epithelial-Mesenchymal Transition - genetics | Breast - metabolism | Cell Movement - genetics | Breast Neoplasms - metabolism | Neoplasm Metastasis | Cell Transformation, Neoplastic - genetics | Vimentin - genetics | Female | Rho Guanine Nucleotide Exchange Factors - metabolism | Cadherins - genetics | Breast - pathology | Proto-Oncogene Proteins - metabolism | Cell Line | Cell Adhesion - genetics | Epithelium - metabolism | Intercellular Junctions - metabolism | Proto-Oncogene Proteins - genetics | Rho Guanine Nucleotide Exchange Factors - genetics | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Blotting, Western | Microscopy, Confocal | Breast Neoplasms - genetics | Biopsy | Breast Neoplasms - pathology | RNA, Small Interfering - metabolism | Stem cells | Physiological aspects | Development and progression | Cytoskeletal proteins | Genetic aspects | Breast cancer | Research | Health aspects | Risk factors | Genotype & phenotype | Tumorigenesis | Metastasis | Gene expression | Phenotypes | Cell survival | Mesenchyme | Epithelial cells | Invasiveness | DNA damage | Pseudopodia | Tumorigenicity | Ribonucleic acid--RNA | Epithelium | K-Ras protein | Metastases | Filaments | Actin | Cytoskeleton | Colonization | Index Medicus
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Loading RightsBiochemical and biophysical research communications, ISSN 0006-291X, 09/2015, Volume 465, Issue 1, pp. 108 - 112
kcat/Km | Carnivorous plants | Drosera adelae | S-like ribonuclease | Protein structure | k cat /K m | Biochemistry & Molecular Biology | Biophysics | Life Sciences & Biomedicine | Science & Technology | Recombinant Proteins - metabolism | Amino Acid Sequence | Gene Expression | Ribonucleases - genetics | Ribonucleases - chemistry | Drosera - chemistry | Models, Molecular | Molecular Sequence Data | Recombinant Proteins - chemistry | Drosera - enzymology | Recombinant Proteins - genetics | Structure-Activity Relationship | Carnivory - physiology | Ribonucleases - metabolism | Plant Proteins - genetics | Sequence Alignment | Escherichia coli - genetics | Plant Proteins - chemistry | Escherichia coli - metabolism | Plant Proteins - metabolism | Kinetics | Mutation | Histidine | Ribonuclease | Plants | Glycine | Analysis | Biomedical engineering | Index Medicus
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Loading RightsNeoplasia (New York, N.Y.), ISSN 1476-5586, 11/2017, Volume 19, Issue 11, pp. 950 - 959
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Loading RightsEnzyme and microbial technology, ISSN 0141-0229, 01/2016, Volume 82, pp. 158 - 163
Xylan | Divalent metal activators | Biofuels | GH43 β-xylosidase | Highest kcat/Km (xylotetraose) | xylotetraose | Highest k | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Amino Acid Sequence | Metagenomics | Catalytic Domain | Escherichia coli | Rumen - enzymology | Molecular Sequence Data | Substrate Specificity | Cations, Divalent - pharmacology | Enzyme Activation - drug effects | Xylosidases - isolation & purification | Recombinant Fusion Proteins - metabolism | Cattle - microbiology | Sequence Homology, Amino Acid | Sequence Alignment | Animals | Glycosides - metabolism | Xylosidases - metabolism | Xylosidases - genetics | Rumen - microbiology | Nitrobenzenes - metabolism | Index Medicus
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Loading RightsBiotechnology and bioengineering, ISSN 0006-3592, 04/2006, Volume 93, Issue 5, pp. 1023 - 1027
increased thermal stability | porcine kidney D‐amino acid oxidase | random mutagenesis | decreased Km value | Increased thermal stability | Decreased K | value | Porcine kidney D-aminoacid oxidase | Random mutagenesis | Life Sciences & Biomedicine | Biotechnology & Applied Microbiology | Science & Technology | Fundamental and applied biological sciences. Psychology | Biotechnology | Biological and medical sciences | D-Amino-Acid Oxidase - chemistry | Temperature | Mutagenesis, Site-Directed | Kidney - enzymology | D-Amino-Acid Oxidase - genetics | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Binding Sites - genetics | Hot Temperature | Recombinant Proteins - biosynthesis | Genetic Vectors - genetics | Animals | Transfection | Escherichia coli - genetics | Swine | Protein Engineering | Amino Acid Substitution - genetics | Protein Conformation | Enzyme Stability - genetics | Kinetics | D-Amino-Acid Oxidase - metabolism | Dimerization | Hydrogen-Ion Concentration | Hogs | Enzymes | Amino acids | Kidneys | Mutation | Index Medicus
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Loading RightsHepatology (Baltimore, Md.), ISSN 0270-9139, 01/2008, Volume 47, Issue 1, pp. 90 - 96
Gastroenterology. Liver. Pancreas. Abdomen | Biological and medical sciences | Medical sciences | Liver. Biliary tract. Portal circulation. Exocrine pancreas | Other diseases. Semiology | Tumors | Genetic Predisposition to Disease | NK Cell Lectin-Like Receptor Subfamily K | Humans | Middle Aged | Cholangitis, Sclerosing - complications | Histocompatibility Antigens Class I - genetics | Cholangiocarcinoma - etiology | Case-Control Studies | Bile Duct Neoplasms - etiology | Receptors, Natural Killer Cell | Adolescent | Alleles | Cholangiocarcinoma - genetics | Adult | Bile Ducts, Intrahepatic | Aged | Polymorphism, Single Nucleotide | Bile Duct Neoplasms - genetics | Receptors, Immunologic - genetics | Child | Index Medicus | Medicin och hälsovetenskap
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Loading RightsPharmacology & therapeutics (Oxford), ISSN 0163-7258, 08/2005, Volume 107, Issue 2, pp. 222 - 239
Validation | Therapy | RNAi | siRNA | Disease | shRNA | Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | RNA, Small Interfering - genetics | RNA Interference - drug effects | Gene Silencing - drug effects | Humans | Respiratory Tract Diseases - drug therapy | Neoplasms - drug therapy | Animals | Communicable Diseases - drug therapy | Neoplasms - genetics | RNA, Small Interfering - therapeutic use | Drug Design | RNA Interference - physiology | RNA, Small Interfering - administration & dosage | Gene Silencing - physiology | Genetic research | Genetic engineering | RNA | Gene expression | Analysis | Index Medicus | LNA, locked nucleic acid | HBV, hepatitis B virus | PEG, polyethylene glycol | SCID, severe combined immunodeficiency | RNAi, RNA interference | TGFβ, transforming growth factor β | COPD, chronic obstructive pulmonary disease | dsRNA, double-stranded RNA | ABCA1, ATP-binding cassette, subfamily A, member 1 | AAV, adeno-associated virus | MDR, multidrug-resistance protein | B-RAF, murine sarcoma viral (v-raf) oncogene homolog B1 oncogene | smad 1, mothers against decapentaplegic homolog 1 | Bcl-2, B-cell chronic lymphocytic leukemia | NF-κB, Nuclear factor-kappaB | LoxP, locus χ of crossover P1 | HIV, human immunodeficiency virus | ERK, extracellular signal regulated protein kinase | lymphoma 2 | VEGF, vascular endothelial growth factor | SARS, severe acute respiratory syndrome | CXCR4, chemokine (C–X–C motif), receptor 4 | Fas, tumour necrosis factor receptor superfamily, member 6 | EGFR, epidermal growth factor receptor | miRNA, microRNAs | EC, endothelial cell | PKR, dsRNA-dependent protein kinase | LPS, lipopolysaccharide | shRNA, short hairpin RNA | BMP4, bone morphogenetic protein 4 | Rnase III, ribonuclease III | MAPK, mitogen-activated protein kinase | KC, keratinocyte-derived chemokine | CCR5, chemokine (C–C motif) receptor 5 | HCV, hepatitis C virus | Cre, causes recombination | BCR-ABL, breakpoint cluster region-protooncogene tyrosine-protein kinase ABL1 fusion protein | smad 7, mothers against decapentaplegic homolog 7 | EpCAM, tumour-associated calcium signal transducer 1 | TLR3, toll-like receptor 3 | S1P, sphingosine 1-phosphate | HMG-CoA, beta-hydroxy-beta-methylglutaryl coenzyme A | RISC, RNA-induced silencing complex | TNFα, tumour necrosis factor α | CML, chronic myelogenous leukemia | bp, base pairs | TGFα, transforming growth factor α | IFN, interferon | CD8, T-lymphocyte differentiation antigen T8 | K-Ras, c-Kirsten-ras protein | RdDM, RNA-directed DNA methylation | siRNA, small interfering RNA | PEI, polyethyleneimine | RasGAP, Ras GTPase-activating protein | MIP2, macrophage inflammatory protein-2 | LacZ, β-galactosidase α-peptide | Leu-2 | RSV, respiratory syncytial virus
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Loading RightsHypertension (Dallas, Tex. 1979), ISSN 0194-911X, 04/2004, Volume 43, Issue 4, pp. 860 - 865
Hypertension | Rats, Dahl | K | Sodium | transporting ATPase | Peripheral Vascular Disease | Life Sciences & Biomedicine | Cardiovascular System & Cardiology | Science & Technology | Cardiology. Vascular system | Arterial hypertension. Arterial hypotension | Biological and medical sciences | Medical sciences | Clinical manifestations. Epidemiology. Investigative techniques. Etiology | Blood and lymphatic vessels | Experimental diseases | Natriuresis - physiology | Arachidonic Acid - metabolism | Potassium Channels - biosynthesis | Sodium-Potassium-Exchanging ATPase - genetics | Blood Pressure - genetics | Kidney Cortex - metabolism | Potassium Channels - physiology | Sodium Chloride, Dietary - administration & dosage | Loop of Henle - metabolism | Male | Sodium - metabolism | Rats, Inbred BN | Chromosomes - genetics | Cytochrome P-450 CYP4A - genetics | Diet, Sodium-Restricted | Sodium-Hydrogen Exchangers - genetics | Blood Pressure - physiology | Ion Transport | Rats, Inbred Dahl | Hypertension - genetics | Genetic Predisposition to Disease | Animals, Genetically Modified | Potassium Channels, Inwardly Rectifying | Rats | Natriuresis - genetics | Sodium-Potassium-Chloride Symporters - genetics | Hypertension - physiopathology | Hypertension - metabolism | Potassium Channels - genetics | Hydroxyeicosatetraenoic Acids - metabolism | Solute Carrier Family 12, Member 1 | Animals | Sodium-Potassium-Chloride Symporters - biosynthesis | Sodium-Potassium-Exchanging ATPase - biosynthesis | Sodium-Potassium-Chloride Symporters - physiology | Kidney Medulla - metabolism | Sodium-Hydrogen Exchangers - biosynthesis | Cytochrome P-450 CYP4A - biosynthesis | Sodium Chloride, Dietary - pharmacokinetics | Sodium-Hydrogen Exchanger 3 | Index Medicus
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Loading RightsNature cell biology, ISSN 1465-7392, 03/2001, Volume 3, Issue 3, pp. 325 - 330
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Cell Line | Phosphorylation | Protein Biosynthesis | Heterogeneous-Nuclear Ribonucleoprotein K | Humans | RNA, Messenger - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Genes, Reporter - genetics | Ribonucleoproteins - metabolism | Heterogeneous-Nuclear Ribonucleoproteins | RNA, Messenger - metabolism | Recombinant Fusion Proteins - metabolism | Blotting, Western | Regulatory Sequences, Nucleic Acid - genetics | Arachidonate 15-Lipoxygenase - genetics | Transfection | Mitogen-Activated Protein Kinases - genetics | Flavonoids - pharmacology | Microscopy, Fluorescence | Mitogen-Activated Protein Kinases - metabolism | Physiological aspects | Research | Nucleoproteins | Protein kinases | Genetic translation | ER kinase | Heterogeneous nuclear ribonucleoprotein K | MAPK kinase | Index Medicus
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