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1. Full Text Do Black-Tailed Prairie Dogs Minimize Inbreeding?
by F. Stephen Dobson and Ronald K. Chesser and John L. Hoogland and Derrick W. Sugg and David W. Foltz
Evolution, ISSN 0014-3820, 6/1997, Volume 51, Issue 3, pp. 970 - 978
Considerable controversy surrounds the importance of inbreeding in natural populations. The rate of natural inbreeding and the influences of behavioral... 
Breeding | Genetic variation | Dogs | Prairies | Inbreeding | Inbreeding coefficient | Evolution | Evolutionary genetics | Population structure | Population genetics | F | social behavior | gene diversity | inbreeding | Cynomys | statistics | gene dynamics | Gene diversity | F-statistics | Social behavior | Gene dynamics | NATURAL-POPULATIONS | GROUND-SQUIRREL | POCKET GOPHERS | K CX BIOLOGY, MISCELLANEOUS | CYNOMYS-LUDOVICIANUS | GENE FLOW | BIOLOGY, MISCELLANEOUS | MATING SYSTEM | K KM GENETICS & HEREDITY | DISPERSAL | SUBDIVIDED POPULATIONS | K GU ECOLOGY | GENETICS & HEREDITY | ECOLOGY | DIVERSITY | Genetic aspects | Prairie dogs | Research | Socialization | Animal reproduction | Genetics | Biology | Animal behavior | Rodents
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2. Full Text Allele-Sharing Models: LOD Scores and Accurate Linkage Tests
by Kong, Augustine and Cox, Nancy J
The American Journal of Human Genetics, ISSN 0002-9297, 1997, Volume 61, Issue 5, pp. 1179 - 1188
Starting with a test statistic for linkage analysis based on allele sharing, we propose an associated one-parameter model. Under general missing-data patterns,... 
Nonparametric tests | Semiparametric models | Allele sharing | LOD scores | Linkage analysis | COMPLEX TRAITS | K KM GENETICS & HEREDITY | GENETICS & HEREDITY | Chromosomes, Human, Pair 2 - genetics | Computer Simulation | Diabetes Mellitus, Type 2 - genetics | Genetic Markers - genetics | Humans | Alleles | Mathematics | Models, Genetic | Software | Genetic Linkage - genetics | Lod Score | Index Medicus
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3. Full Text Genetic Differentiation and Estimation of Gene Flow from F-Statistics Under Isolation by Distance
by Rousset, F
Genetics, ISSN 0016-6731, 04/1997, Volume 145, Issue 4, pp. 1219 - 1228
I reexamine the use of isolation by distance models as a basis for the estimation of demographic parameters from measures of population subdivision. To that... 
PLANT | MODELS | NEW-GUINEA | EQUILIBRIUM | SIZE | GENETICS & HEREDITY | GAINJ-SPEAKING | PAPUA | POPULATION SUBDIVISION | K KM GENETICS & HEREDITY | SNAIL | Genetic Variation | Regression Analysis | Models, Genetic | Gene Frequency | Genetics | Models | Cell differentiation | Cell populations | Statistics | Genes | Index Medicus | Investigations
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4. Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers
by Steck, Peter A and Pershouse, Mark A and Jasser, Samar A and Yung, W.K. Alfred and Lin, Huai and Ligon, Azra H and Langford, Lauren A and Baumgard, Michelle L and Hattier, Thomas and Davis, Thaylon and Frye, Cheryl and Hu, Rong and Swedlund, Bradley and Teng, David H.F and Tavtigian, Scan V
Nature Genetics, ISSN 1061-4036, 04/1997, Volume 15, Issue 4, pp. 356 - 362
Deletions involving regions of chromosome 10 occur in the vast majority (>90%) of human glioblastoma multiformes. A region at chromosome 10q23-24 was... 
AMPLIFICATION | SEQUENCES | HUMAN GLIOBLASTOMAS | PROSTATE-CANCER | MXI1 GENE | REGIONS | GENETICS & HEREDITY | LOCI | HETEROZYGOSITY | PROGRESSION | K KM GENETICS & HEREDITY | LONG ARM | Amino Acid Sequence | Humans | Cells, Cultured | Gene Expression Regulation, Neoplastic | Genes, Tumor Suppressor - genetics | Molecular Sequence Data | RNA, Messenger - analysis | Male | Mutation - genetics | Sequence Homology, Amino Acid | Phosphoric Monoester Hydrolases | Protein Tyrosine Phosphatases - genetics | RNA, Neoplasm - analysis | Animals | Glioblastoma - genetics | Neoplasms - genetics | PTEN Phosphohydrolase | DNA Mutational Analysis | Mice | Chromosomes, Human, Pair 10 - genetics | Tumor Cells, Cultured | Tumor Suppressor Proteins
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5. Full Text Genomic Libraries and a Host Strain Designed for Highly Efficient Two-Hybrid Selection in Yeast
by James, P and Halladay, J and Craig, E. A
Genetics, ISSN 0016-6731, 12/1996, Volume 144, Issue 4, pp. 1425 - 1436
The two-hybrid system is a powerful technique for detecting protein-protein interactions that utilizes the well-developed molecular genetics of the yeast... 
PROTEIN PHOSPHATASE | 2-HYBRID SYSTEM | GENE | DNA | KINASE | GENETICS & HEREDITY | SACCHAROMYCES-CEREVISIAE | CHROMOSOME-III | VECTORS | NUCLEOTIDE-SEQUENCE | CLONE | K KM GENETICS & HEREDITY | Nucleic Acid Hybridization | Gene Library | Genome, Fungal | Saccharomyces cerevisiae - genetics | Base Sequence | Plasmids - genetics | Molecular Sequence Data | Genetic Vectors | Genetic aspects | Saccharomyces | Research | Genetic translation | Protein binding | Proteins | Enzymes | Genetics | Yeast | Index Medicus | Investigations
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6. Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome
by Liaw, D and Marsh, D.J and Li, J and Dahia, P.L.M and Wang, S.I and Zheng, Z and Bose, S and Call, K.M and Tsou, H.C and Peacocke, M and Eng, C and Parsons, R
Nature Genetics, ISSN 1061-4036, 1997, Volume 16, Issue 1, pp. 64 - 67
Cowden disease (CD) is an autosomal dominant cancer predisposition syndrome associated with an elevated risk for tumours of the breast, thyroid and skin(1-2).... 
LHERMITTE-DUCLOS DISEASE | K KM GENETICS & HEREDITY | GENETICS & HEREDITY | Hamartoma Syndrome, Multiple - genetics | Humans | Genes, Tumor Suppressor - genetics | Male | Polymorphism, Genetic | Phosphoric Monoester Hydrolases | Protein Tyrosine Phosphatases - genetics | Breast Neoplasms - genetics | PTEN Phosphohydrolase | DNA Mutational Analysis | Pedigree | Germ-Line Mutation | Female | Breast Neoplasms - diagnosis | Tumor Suppressor Proteins
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7. KILLER/DR5 is a DNA damage-inducible p53-regulated death receptor gene
by Wu, G.S and Wu, Gen Sheng and Burns, Timothy F and Burns, T.F and McDonald, E. Robert and McDonald 3rd, E.R and Jiang, W and Jiang, Wen and Meng, Ray and Meng, R and Krantz, Ian D and Krantz, I.D and Kao, Gary and Kao, G and Gan, Dai-Di and Gan, D.D and Zhou, Jun-Ying and Zhou, J.Y and Muschel, R and Muschel, Ruth and Hamilton, Stanley R and Hamilton, S.R and Spinner, N.B and Spinner, Nancy B and Markowitz, Sanford and Markowitz, S and Wu, Gary and Wu, G and El-Deiry, Wafik S and el-Deiry, W.S
Nature genetics, ISSN 1061-4036, 1997, Volume 17, Issue 2, pp. 141 - 143
P53 (also known as TP53), the cellular `gatekeeper for growth and division', is the most commonly mutated gene in human cancer, and its inactivation... 
MICE | K KM GENETICS & HEREDITY | GENETICS & HEREDITY | P53 | Amino Acid Sequence | Chromosomes, Human, Pair 8 - genetics | Humans | RNA, Messenger - genetics | Molecular Sequence Data | Receptors, TNF-Related Apoptosis-Inducing Ligand | DNA - genetics | Sequence Homology, Amino Acid | Genes, p53 | Cell Death - genetics | Base Sequence | DNA Damage | Receptors, Tumor Necrosis Factor - genetics
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8. Toward a functional analysis of the yeast genome through exhaustive two- hybrid screens
by Fromont-Racine, M and Rain, J.-C and Legrain, P
Nature Genetics, ISSN 1061-4036, 1997, Volume 16, Issue 3, pp. 277 - 282
The genome of the yeast Saccharomyces cerevisiae is now completely sequenced. Despite successful genetic work in recent years, 60% of yeast genes have no... 
SPLICING FACTORS | U6 | 2-HYBRID SYSTEM | COMPLEX | IDENTIFY | PRP11 | GENETICS & HEREDITY | PROTEIN-PROTEIN INTERACTIONS | SM | IDENTIFICATION | U2 | K KM GENETICS & HEREDITY | Amino Acid Sequence | Saccharomyces cerevisiae - genetics | Genomic Library | Molecular Sequence Data | Ribonucleoproteins, Small Nuclear - genetics | Fungal Proteins - genetics | Genetic Techniques | Open Reading Frames - genetics | Sequence Alignment | Genome, Fungal | RNA Splicing - genetics | Crosses, Genetic | Fungal Proteins - metabolism
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9. Positional cloning of the APECED gene
by Nagamine, Kentaro and Peterson, Pärt and Scott, Hamish S and Kudoh, Jun and Minoshima, Shinsei and Heino, Maarit and Krohn, Kai J.E and Lalioti, Maria D and Mullis, Primus E and Antonarakis, Stylianos E and Kawasaki, Kazuhiko and Asakawa, Shuichi and Ito, Fumiaki and Shimizu, Nobuyoshi
Nature Genetics, ISSN 1061-4036, 1997, Volume 17, Issue 4, pp. 393 - 398
Autoimmune polyglandular syndrome type I (APS 1, also called APECED) is an autosomal-recessive disorder that maps to human chromosome 21q22.3 between markers... 
PROTEIN | SEQUENCES | 21Q22.3 | GENETICS & HEREDITY | CDNA | DISEASE TYPE-I | K KM GENETICS & HEREDITY | REGION | Haplotypes | Amino Acid Sequence | Transcription Factors - chemistry | Humans | Molecular Sequence Data | Transcription Factors - biosynthesis | Transcription Factors - genetics | Organ Specificity - genetics | RNA, Messenger - biosynthesis | DNA Mutational Analysis | Cloning, Molecular - methods | Zinc Fingers - genetics | Polyendocrinopathies, Autoimmune - genetics | Chromosomes, Human, Pair 21
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10. Full Text Testing Differentiation in Diploid Populations
by Goudet, J and Raymond, M and de-Meeus, T and Rousset, F and Uppsala universitet
Genetics, ISSN 0016-6731, 12/1996, Volume 144, Issue 4, pp. 1933 - 1940
We examine the power of different exact tests of differentiation for diploid populations. Since there is not necessarily random mating within populations, the... 
ALLELES | DETECTING GEOGRAPHIC SUBDIVISION | GENE FLOW | K KM GENETICS & HEREDITY | F-STATISTICS | GENETICS & HEREDITY | Genetics, Population | Diploidy | Animals | Humans | Alleles | Genotype | Models, Genetic | Research | Cell differentiation | Population genetics | Genetics | Statistical analysis | Genes | Tests | Index Medicus | Investigations | DETECTING GEOGRAPHIC SUBDIVISION; F-STATISTICS; GENE FLOW; ALLELES
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11. An autoimmune disease, APECED, caused by mutations in a novel gene featuring two PHD-type zinc-finger domains
by Aaltonen, Johanna and Björses, Petra and Perheentupa, Jaakko and Horelli-Kuitunen, Nina and Palotie, Aarno and Peltonen, Leena and Lee Su, Yeon and Francis, Fiona and Hennig, Steffen and Thiel, Cora and Lehrach, Hans and Yaspo, Marie-Laure and Finnish-German APECED Consortium
Nature Genetics, ISSN 1061-4036, 1997, Volume 17, Issue 4, pp. 399 - 403
Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is the only described systemic autoimmune disease with established monogenic... 
PHOSPHOFRUCTOKINASE GENE | EXON | CODING REGIONS | PROTEIN | SEQUENCES | GENETICS & HEREDITY | CANDIDIASIS | AUTOANTIGEN | MODEL | HUMAN DNA | IDENTIFICATION | K KM GENETICS & HEREDITY | Amino Acid Sequence | Transcription Factors - chemistry | Nuclear Proteins - isolation & purification | Exons | Introns | Humans | Molecular Sequence Data | Transcription Factors - genetics | Nuclear Proteins - chemistry | Cloning, Molecular | Transcription Factors - isolation & purification | Zinc Fingers - genetics | Polyendocrinopathies, Autoimmune - genetics | Mutation | Nuclear Proteins - genetics
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12. Full Text Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histones: Characterization of an ada complex and the saga (spt/ada) complex
by Grant, Patrick A and Duggan, Laura and Côté, Jacques and Roberts, Shannon M and Brownell, James E and Candau, Reyes and Ohba, Reiko and Owen-Hughes, Tom and Allis, C. David and Winston, Fred and Berger, Shelley L and Workman, Jerry L
Genes and Development, ISSN 0890-9369, 07/1997, Volume 11, Issue 13, pp. 1640 - 1650
The transcriptional adaptor protein Gcn5 has been identified as a nuclear histone acetyltransferase (HAT). Although recombinant yeast Gcn5 efficiently... 
Acetyltransferase | Gen5 | Transcription | Nucleosome | Spt | Ada | Gcn5 | ACIDIC ACTIVATION DOMAINS | transcription | POLYMERASE-II HOLOENZYME | CHROMATIN STRUCTURE | FACILITATED BINDING | K HY DEVELOPMENTAL BIOLOGY | DEVELOPMENTAL BIOLOGY | GENE ENCODES | SACCHAROMYCES-CEREVISIAE | K KM GENETICS & HEREDITY | TATA-BINDING PROTEIN | PUTATIVE TRANSCRIPTIONAL ADAPTER | AMINO TERMINI | GENETICS & HEREDITY | nucleosome | acetyltransferase | LINKING NUMBER CHANGE | Protein Kinases - metabolism | Acetyltransferases - metabolism | Protein Kinases - genetics | Histone Acetyltransferases | Saccharomyces cerevisiae - genetics | Multienzyme Complexes - metabolism | Nucleosomes - metabolism | Substrate Specificity | Multienzyme Complexes - genetics | Fungal Proteins - genetics | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Acetyltransferases - genetics | Recombinant Fusion Proteins - metabolism | DNA-Binding Proteins - metabolism | Transcription Factors - metabolism | Saccharomyces cerevisiae Proteins | Recombinant Fusion Proteins - genetics | Saccharomyces cerevisiae - enzymology | Acetylation | Catalysis | Histones - metabolism | Fungal Proteins - metabolism | Index Medicus
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13. Mutations in the human Jagged1 gene are responsible for Alagille syndrome
by Oda, Takaya and Elkahloun, Abdel G and Pike, Brian L and Okajima, Kazuki and Krantz, Ian D and Genin, Anna and Piccoli, David A and Meltzer, Paul S and Spinner, Nancy B and Collins, Francis S and Chandrasekharappa, Settara C
Nature Genetics, ISSN 1061-4036, 1997, Volume 16, Issue 3, pp. 235 - 242
Alagille syndrome (AGS) is an autosomal-dominant disorder characterized by intrahepatic cholestasis and abnormalities of heart, eye and vertebrae, as well as a... 
20P | MICRODELETIONS | ARTERIOHEPATIC DYSPLASIA | GENETICS & HEREDITY | NOTCH | CHROMOSOME-20 | DROSOPHILA | K KM GENETICS & HEREDITY | DELETION | FAMILY | REGION | Humans | Gene Expression Regulation, Developmental - genetics | Receptors, Cell Surface | Polymorphism, Single-Stranded Conformational | Alagille Syndrome - genetics | DNA Mutational Analysis | Serrate-Jagged Proteins | RNA Splicing - genetics | Cloning, Molecular | Membrane Proteins - metabolism | Jagged-1 Protein | Cell Line | Calcium-Binding Proteins | Introns - genetics | Membrane Proteins - genetics | Intercellular Signaling Peptides and Proteins | Exons - genetics | In Situ Hybridization, Fluorescence | Chromosome Mapping | DNA Primers | Sequence Analysis, DNA | Membrane Proteins - chemistry | Transcription Factors | Mutation | Receptor, Notch1 | Chromosomes, Human, Pair 20 - genetics | Sequence Deletion - genetics
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14. Full Text Markov Chain Monte Carlo Segregation and Linkage Analysis for Oligogenic Models
by Heath, Simon C
The American Journal of Human Genetics, ISSN 0002-9297, 1997, Volume 61, Issue 3, pp. 748 - 760
A new method for segregation and linkage analysis, with pedigree data, is described. Reversible jump Markov chain Monte Carlo methods are used to implement a... 
GENETIC-ANALYSIS | IRREDUCIBILITY | GENETICS & HEREDITY | PEDIGREE DATA | SIMULATION | TRAITS | LIKELIHOOD | K KM GENETICS & HEREDITY | Markov Chains | Phenotype | Pedigree | Computer Simulation | Humans | Models, Genetic | Monte Carlo Method | Genetic Linkage | Index Medicus
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