X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (3902) 3902
Book Chapter (30) 30
Conference Proceeding (30) 30
Dissertation (16) 16
Magazine Article (11) 11
Newspaper Article (6) 6
Government Document (4) 4
Web Resource (4) 4
Publication (3) 3
Book / eBook (1) 1
Paper (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
science & technology (2580) 2580
humans (2181) 2181
life sciences & biomedicine (2058) 2058
mutation (1646) 1646
k-ras (1423) 1423
k-ras protein (1409) 1409
oncology (1395) 1395
female (1193) 1193
male (1014) 1014
cancer (967) 967
middle aged (849) 849
tumors (822) 822
aged (791) 791
animals (704) 704
colorectal cancer (685) 685
adult (599) 599
genes, ras (584) 584
genetic aspects (557) 557
mice (522) 522
polymerase chain reaction (512) 512
science & technology - other topics (500) 500
genes, ras - genetics (498) 498
multidisciplinary sciences (488) 488
colorectal neoplasms - genetics (456) 456
lung cancer (456) 456
medicine (437) 437
signal transduction (425) 425
proteins (423) 423
pancreatic cancer (422) 422
kinases (421) 421
pathology (411) 411
cell line, tumor (410) 410
research article (406) 406
proto-oncogene proteins p21 - genetics (399) 399
aged, 80 and over (392) 392
lung neoplasms - genetics (386) 386
science (385) 385
gene expression (381) 381
adenocarcinoma - genetics (364) 364
research (359) 359
analysis (355) 355
cell biology (355) 355
colorectal carcinoma (345) 345
metastasis (341) 341
adenocarcinoma (339) 339
prognosis (332) 332
epidermal growth factor receptors (330) 330
ras proteins - genetics (328) 328
point mutation (320) 320
pancreatic neoplasms - genetics (313) 313
biochemistry & molecular biology (311) 311
p53 (305) 305
patients (305) 305
deoxyribonucleic acid--dna (300) 300
metastases (300) 300
colorectal neoplasms - pathology (298) 298
immunohistochemistry (285) 285
apoptosis (282) 282
gene mutations (278) 278
genes (273) 273
chemotherapy (270) 270
dna mutational analysis (265) 265
lung neoplasms - pathology (260) 260
gene expression regulation, neoplastic (255) 255
cell proliferation (250) 250
proto-oncogene proteins - genetics (243) 243
proto-oncogene proteins p21 (242) 242
k-ras gene (232) 232
adenocarcinoma - pathology (227) 227
health aspects (227) 227
care and treatment (224) 224
biology (223) 223
pancreatic neoplasms - pathology (222) 222
digestive system diseases (220) 220
base sequence (215) 215
cancer therapies (212) 212
epidermal growth factor (212) 212
p53 protein (211) 211
neoplasms (210) 210
surgery (210) 210
medical prognosis (209) 209
genetics (207) 207
gastroenterology & hepatology (205) 205
tumorigenesis (201) 201
dna (197) 197
mutation - genetics (196) 196
genetics & heredity (193) 193
survival (189) 189
k-ras mutation (185) 185
k‐ras (185) 185
development and progression (181) 181
neoplasm staging (177) 177
medical research (172) 172
biomarkers (167) 167
phosphorylation (167) 167
ras proteins - metabolism (167) 167
signaling (167) 167
carcinoma, non-small-cell lung - genetics (163) 163
cancers and neoplasms (162) 162
proto-oncogene proteins p21 - metabolism (162) 162
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (3477) 3477
Chinese (433) 433
Japanese (57) 57
German (22) 22
French (18) 18
Spanish (14) 14
Korean (13) 13
Czech (11) 11
Portuguese (8) 8
Polish (7) 7
Russian (4) 4
Hungarian (3) 3
Catalan (1) 1
Italian (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Angewandte Chemie (International ed.), ISSN 1433-7851, 01/2014, Volume 53, Issue 1, pp. 199 - 204
We report the synthesis of a GDP analogue, SML‐8‐73‐1, and a prodrug derivative, SML‐10‐70‐1, which are selective, direct‐acting covalent inhibitors of the... 
covalent inhibitors | cancer | K‐Ras | drug design | K-Ras | ras Proteins - metabolism | ras Proteins - genetics | Signal Transduction | ras Proteins - chemistry | Catalytic Domain - genetics | Drug Design | Purines | Nuclear radiation | Gross domestic product | Health aspects | Binding sites | Index Medicus | Proteins | Covalence | Inhibitors | Strategy | Biochemistry | Derivatives | Inhibition | Covalent inhibitor | Drug design | Cancer
Journal Article
International journal of oncology, ISSN 1019-6439, 03/2019, Volume 54, Issue 3, pp. 807 - 820
Accumulating evidence has indicated that the dysregulation of microRNAs (miRNAs) is involved in the pathogenesis o retinoblastoma (RB); however, the potential... 
Insulin-like growth factor-1 receptor/k-Ras/Raf/mitogen activated protein kinase kinase/ extracellular signal-regulated kinase signaling pathway | MicroRNA-98 | Retinoblastoma | Prognostic biomarker | Life Sciences & Biomedicine | Oncology | Science & Technology
Journal Article
PloS one, ISSN 1932-6203, 2017, Volume 12, Issue 4, pp. e0176578 - e0176578
[This corrects the article DOI: 10.1371/journal.pone.0149099.]. 
Medical research | Cancer | K-Ras protein | Tumors
Journal Article
Cancer research (Chicago, Ill.), ISSN 0008-5472, 02/2018, Volume 78, Issue 3, pp. 593 - 602
Journal Article
Journal Article
Cell research, ISSN 1001-0602, 2017, Volume 27, Issue 7, pp. 916 - 932
Pancreatic ductal adenocarcinoma (PDAC) driven by oncogenic K-Ras remains among the most lethal human cancers despite recent advances in modern medicine. The... 
Life Sciences & Biomedicine | Science & Technology | Cell Biology | Pancreatic Neoplasms - metabolism | Prognosis | Oxidative Stress | Tumor Suppressor Proteins - antagonists & inhibitors | Humans | Carcinoma, Pancreatic Ductal - metabolism | Carcinogenesis - metabolism | HMGB1 Protein - genetics | Carcinoma, Pancreatic Ductal - genetics | Neoplasm Metastasis | Glycyrrhizic Acid - pharmacology | Interleukin-6 - blood | HMGB1 Protein - metabolism | Tumor Suppressor Proteins - genetics | Neoplasms, Experimental | Telomere - metabolism | Chromosomal Instability | HMGB1 Protein - antagonists & inhibitors | Genes, ras - genetics | Telomere - genetics | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Carcinogenesis - genetics | Kaplan-Meier Estimate | Nucleosomes - metabolism | Pancreatic Neoplasms - genetics | Mice, Knockout | Animals | Mice | DNA Damage | Cohort Studies | Adenocarcinoma | Pathogenesis | DNA damage | Interleukin | Antibodies | Macrophages | Chromosome rearrangements | HMGB1 protein | Neoplasms | K-Ras protein | Genomic instability | Metastases | Interleukin 6 | Cell activation | Rodents | Tumorigenesis | Inhibition | Lesions | Pancreas | Chromosomes | Deoxyribonucleic acid--DNA | Glycyrrhizin | Advanced glycosylation end products | Stability | Abnormalities | Leukocytes (neutrophilic) | Pharmacology | Inflammation | Glycosylation | Survival | Ablation | Pancreatic cancer | Neutralizing | Nucleosomes | Tumor suppressor genes | Intracellular | Histone H3 | Tumors | Cancer | Index Medicus | pancreatic cancer | HMGB1 | RAGE | histone | K-Ras | Original
Journal Article
Oncogene, ISSN 0950-9232, 2014, Volume 33, Issue 46, pp. 5391 - 5396
Lung cancer is the leading cause of deaths in cancer patients in the United States. Identification of new molecular targets is clearly needed to improve... 
Non-small-cell lung cancer | K-Ras | FOXM1 | Transgenic mice | Signal transduction | Protein expression | Tumorigenesis | Transgenic animals | Lung cancer
Journal Article
Journal Article