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k14-hpv16 transgenic mice (32) 32
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uterine cervical neoplasms - pathology (5) 5
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Life Sciences, ISSN 0024-3205, 04/2017, Volume 175, pp. 31 - 36
Journal Article
Journal of Cancer Research and Clinical Oncology, ISSN 0171-5216, 2/2018, Volume 144, Issue 2, pp. 241 - 248
Persistent human papillomavirus (HPV) infection is associated with the development of certain types of cancer and the dysregulation of microRNAs has been... 
MiR-146a | K14-HPV16 transgenic mice | Dysplasia | Medicine & Public Health | Hematology | Carcinoma in situ | Hyperplasia | Oncology | Cancer Research | Internal Medicine | HPV16 | CANCER | CD8(+) T-CELLS | PAPILLOMAVIRUS-INDUCED LESIONS | MICROENVIRONMENT | ONCOLOGY | NF-KAPPA-B | E5 ONCOPROTEIN | Genetic engineering | MicroRNA | Carcinogenesis | Papillomavirus infections | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 2010, Volume 17, Issue 2, pp. 121 - 134
Chronically activated leukocytes recruited to premalignant tissues functionally contribute to cancer development; however, mechanisms underlying pro- versus... 
CELLCYCLE | MOLIMMUNO | CELLIMMUNO | PRIMARY TUMORS | ANGIOGENESIS | ONCOLOGY | MACROPHAGES | MAST-CELLS | TIE2-EXPRESSING MONOCYTES | GROWTH | HUMORAL IMMUNITY | K14-HPV16 TRANSGENIC MICE | RECEPTORS | CANCER
Journal Article
Cancer research, ISSN 0008-5472, 10/2009, Volume 69, Issue 20, pp. 7945 - 7952
Non-invasive detection of dysplasia provides a potential platform for monitoring the efficacy of chemopreventive therapy of premalignancy, imaging the tissue... 
dysplasia | cervix | DCE-MRI | K14-HPV16 | angiogenesis
Journal Article
In Vivo, ISSN 0258-851X, 03/2012, Volume 26, Issue 2, pp. 207 - 211
While cervical cancer incidence and mortality rates have declined in the United States, this. cancer represents a worldwide threat. Human papilloma viral... 
Gas chromatography | Serum estrogen metabolites | Interferon-γ | 3,3′-Diindolylmethane | K14-HPV16 transgenic mouse model | Cancer prevention | Cervical cancer | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | cancer prevention | PREVENTION | serum estrogen metabolites | gas chromatography | 3,3 '-diindolylmethane | MASS-SPECTROMETRY | ESTROGEN METABOLISM | PAPILLOMATOSIS | IN-VIVO | INDOLE-3-CARBINOL | MICE | interferon-gamma | Estradiol - blood | Carcinoma, Squamous Cell - blood | Cervical Intraepithelial Neoplasia - blood | Cervical Intraepithelial Neoplasia - pathology | Estradiol - analogs & derivatives | Papillomavirus E7 Proteins - physiology | Carcinoma, Squamous Cell - pathology | Indoles - administration & dosage | Neoplasms, Hormone-Dependent - genetics | Anticarcinogenic Agents - administration & dosage | Papillomavirus E7 Proteins - biosynthesis | Transgenes | Anticarcinogenic Agents - pharmacology | Administration, Oral | Repressor Proteins - genetics | Mice, Transgenic | Uterine Cervical Neoplasms - genetics | Keratin-14 - genetics | Neoplasms, Hormone-Dependent - blood | Repressor Proteins - biosynthesis | Cervical Intraepithelial Neoplasia - prevention & control | Recombinant Fusion Proteins - genetics | Indoles - therapeutic use | Cervical Intraepithelial Neoplasia - genetics | Mice | Epithelial Cells - metabolism | Carcinoma, Squamous Cell - genetics | Recombinant Fusion Proteins - physiology | Uterine Cervical Neoplasms - blood | Uterine Cervical Neoplasms - pathology | Papillomavirus E7 Proteins - genetics | Dose-Response Relationship, Drug | Repressor Proteins - physiology | Female | Indoles - pharmacology | Oncogene Proteins, Viral - genetics | Anticarcinogenic Agents - therapeutic use | Neoplasms, Hormone-Dependent - prevention & control | Oncogene Proteins, Viral - physiology | Recombinant Fusion Proteins - biosynthesis | Promoter Regions, Genetic | Uterine Cervical Neoplasms - prevention & control | Carcinoma, Squamous Cell - prevention & control | Oncogene Proteins, Viral - biosynthesis | Estradiol - pharmacokinetics | Animals | Estradiol - toxicity | Neoplasms, Hormone-Dependent - pathology | Human papillomavirus 16 - genetics | Interferon-gamma - blood | Index Medicus
Journal Article
Cancer Cell, ISSN 1535-6108, 06/2014, Volume 25, Issue 6, pp. 809 - 821
B cells foster squamous cell carcinoma (SCC) development through deposition of immunoglobulin-containing immune complexes in premalignant tissue and Fcγ... 
BREAST-CANCER | IMMUNITY | ONCOLOGY | OROPHARYNGEAL CANCER | MOUSE MODEL | SKIN CARCINOGENESIS | CERVICAL-CANCER | HUMAN-PAPILLOMAVIRUS | RESISTANT PROSTATE-CANCER | K14-HPV16 TRANSGENIC MICE | T-CELLS | CELL BIOLOGY | CD8-Positive T-Lymphocytes - pathology | Cricetulus | Carcinoma, Squamous Cell - pathology | Humans | Tumor Microenvironment | Organoplatinum Compounds - administration & dosage | Female | B-Lymphocytes - pathology | Paclitaxel - administration & dosage | Macrophages - immunology | CHO Cells | Macrophages - pathology | Mice, Transgenic | Carcinoma, Squamous Cell - immunology | Neoplasms - drug therapy | Xenograft Model Antitumor Assays | B-Lymphocytes - drug effects | Phenotype | Animals | B-Lymphocytes - immunology | Carcinoma, Squamous Cell - drug therapy | Lymphocytes, Tumor-Infiltrating - pathology | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasms - immunology | Macrophages - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Neoplasms - pathology | Lymphocytes, Tumor-Infiltrating - immunology | Antimitotic agents | Squamous cell carcinoma | Chemotherapy | Developmental biology | Nuclear radiation | Monoclonal antibodies | Genetic aspects | B cells | Antineoplastic agents | Macrophages | Cancer | Index Medicus | CD8 T cell | CD20 | B cell | humoral immunity | immunoglobulin | inflammation | macrophage | chemotherapy
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 05/2012, Volume 122, Issue 5, pp. 1832 - 1848
Cancer development, progression, and metastasis are highly dependent on angiogenesis. The use of antiangiogenic drugs has been proposed as a novel strategy to... 
MEDICINE, RESEARCH & EXPERIMENTAL | VASCULAR NORMALIZATION | INDUCIBLE FACTOR-1-ALPHA | SQUAMOUS CARCINOGENESIS | PANCREATIC NEUROENDOCRINE TUMORS | MOUSE MODEL | ANTI-ANGIOGENIC THERAPY | GROWTH-FACTOR | K14-HPV16 TRANSGENIC MICE | NF-KAPPA-B | MALIGNANT PROGRESSION | Proto-Oncogene Proteins c-met - metabolism | Genetic Therapy | Pancreatic Neoplasms - metabolism | Uterine Cervical Neoplasms - blood supply | Pancreatic Neoplasms - blood supply | Drug Resistance, Neoplasm | NF-kappa B - metabolism | Uterine Cervical Neoplasms - pathology | Recombinant Proteins - biosynthesis | Semaphorin-3A - biosynthesis | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Pericytes - pathology | Epithelial-Mesenchymal Transition | Angiogenesis Inhibitors - therapeutic use | Female | Indoles - pharmacology | Liver Neoplasms - secondary | Pyrroles - therapeutic use | Uterine Cervical Neoplasms - therapy | Semaphorin-3A - genetics | Neuroendocrine Tumors - pathology | Cell Hypoxia - drug effects | Neoplasm Invasiveness | Neuroendocrine Tumors - metabolism | Pancreatic Neoplasms - pathology | Angiogenesis Inhibitors - pharmacology | Mice, Transgenic | Combined Modality Therapy | Lymphatic Metastasis | Recombinant Proteins - genetics | Tumor Burden | Pyrroles - pharmacology | Animals | Uterine Cervical Neoplasms - virology | Indoles - therapeutic use | Mice | Neuroendocrine Tumors - therapy | Neovascularization, Physiologic | Neuroendocrine Tumors - blood supply | Pancreatic Neoplasms - therapy | Research | Angiogenesis inhibitors | Semaphorins | Cancer cells | Index Medicus | Abridged Index Medicus
Journal Article
Anticancer Research, ISSN 0250-7005, 03/2018, Volume 38, Issue 3, pp. 1461 - 1466
Journal Article
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 09/2004, Volume 114, Issue 5, pp. 623 - 633
A mouse model involving the human papillomavirus type-16 oncogenes develops cervical cancers by lesional. stages analogous to those in humans. In this study... 
ZOLEDRONIC ACID | MEDICINE, RESEARCH & EXPERIMENTAL | MATRIX METALLOPROTEINASES | IN-VITRO | SQUAMOUS CARCINOGENESIS | TUMOR PROGRESSION | PROSTATE-CANCER CELLS | K14-HPV16 TRANSGENIC MICE | OSTEOCLAST DIFFERENTIATION | ENDOTHELIAL GROWTH-FACTOR | MEMBRANE LOCALIZATION
Journal Article
JOURNAL OF INVESTIGATIVE DERMATOLOGY, ISSN 0022-202X, 02/2016, Volume 136, Issue 2, pp. 473 - 480
Human papillomavirus (HPV) infection is estimated to be the causal agent in 5% of all human cancers and is the leading cause of genital warts, which is the... 
MIGRATION | CARCINOGENESIS | DENDRITIC CELLS | RAPID MOBILIZATION | PATHWAY | IFN-GAMMA | AMD3100 | WHIM-SYNDROME | HYPERPLASTIC SKIN | K14-HPV16 TRANSGENIC MICE | DERMATOLOGY
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2017, Volume 114, Issue 43, pp. E9056 - E9065
It has been shown that gamma delta T cells protect against the formation of squamous cell carcinoma (SCC) in several models. However, the role of gamma delta T... 
ANGIOGENESIS | MULTIDISCIPLINARY SCIENCES | gamma delta T cells | viral oncogene | interleukin 17 | INNATE | gammadelta | RECEPTOR | K14-HPV16 TRANSGENIC MICE | INTRAEPITHELIAL NEOPLASIA | CERVICAL NEOPLASIA | CANCER | INTERFERON-GAMMA | SKIN CARCINOGENESIS | functional heterogeneity | PIVOTAL ROLE
Journal Article