X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
kahalalide-f (64) 64
humans (52) 52
index medicus (52) 52
animals (39) 39
pharmacology & pharmacy (34) 34
kahalalide f (33) 33
oncology (25) 25
antineoplastic agents - pharmacology (24) 24
cancer (24) 24
chemistry, medicinal (22) 22
antineoplastic agents - chemistry (21) 21
biochemistry & molecular biology (19) 19
depsipeptides - pharmacology (19) 19
mollusk elysia-rufescens (18) 18
antineoplastic agents - therapeutic use (17) 17
depsipeptides - chemistry (17) 17
natural-products (16) 16
neoplasms - drug therapy (16) 16
apoptosis (14) 14
peptides (14) 14
antineoplastic agents (12) 12
aquatic organisms - chemistry (12) 12
cell line, tumor (12) 12
drug discovery (12) 12
female (11) 11
in-vitro (11) 11
advanced solid tumors (10) 10
antineoplastic agents - isolation & purification (10) 10
biology (10) 10
clinical trials (10) 10
depsipeptide (10) 10
depsipeptides (10) 10
depsipeptides - therapeutic use (10) 10
marine biology (10) 10
peptides - chemistry (10) 10
biological products - chemistry (9) 9
chemistry, organic (9) 9
chemotherapy (9) 9
cytotoxicity (9) 9
drugs (9) 9
pm02734 (9) 9
male (8) 8
marine natural products (8) 8
phase-i (8) 8
research (8) 8
adult (7) 7
article (7) 7
biological products - pharmacology (7) 7
cell lung-cancer (7) 7
clinical trials as topic (7) 7
depsipeptides - adverse effects (7) 7
depsipeptides - pharmacokinetics (7) 7
dolastatin 10 (7) 7
drug screening assays, antitumor (7) 7
medicine & public health (7) 7
molecular structure (7) 7
peptides - pharmacology (7) 7
pharmacology/toxicology (7) 7
phase-ii trial (7) 7
review (7) 7
aged (6) 6
anticancer (6) 6
antimitotic agents (6) 6
antineoplastic agents - adverse effects (6) 6
antineoplastic agents - pharmacokinetics (6) 6
aplidine (6) 6
bioactive peptides (6) 6
biological products - isolation & purification (6) 6
care and treatment (6) 6
chromatography, high pressure liquid (6) 6
compound (6) 6
cyanobacterium lyngbya-majuscula (6) 6
drug stability (6) 6
ecteinascidin-743 (6) 6
elisidepsin (6) 6
hela cells (6) 6
marine (6) 6
marine organisms (6) 6
medical research (6) 6
middle aged (6) 6
neoplasms - pathology (6) 6
peptide (6) 6
peptides, cyclic - chemistry (6) 6
structure-activity relationship (6) 6
tumors (6) 6
antitumor-activity (5) 5
apoptosis - drug effects (5) 5
biotechnology & applied microbiology (5) 5
breast cancer (5) 5
breast neoplasms - drug therapy (5) 5
breast-cancer cells (5) 5
depsipeptides - isolation & purification (5) 5
didemnin-b (5) 5
drug evaluation, preclinical (5) 5
metabolites (5) 5
peptides, cyclic - pharmacology (5) 5
toxicity (5) 5
aged, 80 and over (4) 4
agent (4) 4
analysis (4) 4
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Organic Letters, ISSN 1523-7060, 12/2015, Volume 17, Issue 24, pp. 6182 - 6185
Journal Article
NATURAL PRODUCT REPORTS, ISSN 0265-0568, 5/2019, Volume 36, Issue 5, pp. 81 - 841
Covering: 1957 to 2017 Algae constitute a heterogeneous group of eukaryotic photosynthetic organisms, mainly found in the marine environment. Algae produce... 
HALOGENATED MONOTERPENES | MARINE RED ALGA | CHEMISTRY, MEDICINAL | NATURAL-PRODUCT DRUGS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | OVERCOME MULTIDRUG-RESISTANCE | MOLLUSK ELYSIA-RUFESCENS | CANCER STEM-CELLS | BROWN-ALGA | KAHALALIDE F ANALOGS | BROMINATED DITERPENES | PHASE-I
Journal Article
JOURNAL OF NATURAL PRODUCTS, ISSN 0163-3864, 02/2016, Volume 79, Issue 2, pp. 421 - 427
We validate the improved resolution and sensitivity of the C-3 Marfey's method, including an ability to resolve all Ile-isomers, against an array of amino... 
UNIDENTIFIED ASCOMYCETE OK-128 | CHEMISTRY, MEDICINAL | SPONGE PROSUBERITES-LAUGHLINI | MARINE-DERIVED FUNGUS | CYCLIC-PEPTIDES | MASS-SPECTROMETRY | PLANT SCIENCES | STREPTOMYCES SP | KAHALALIDE-F | ABSOLUTE-CONFIGURATION | LIQUID-CHROMATOGRAPHY | PHARMACOLOGY & PHARMACY | CYANOBACTERIUM LYNGBYA-MAJUSCULA
Journal Article
MARINE DRUGS, ISSN 1660-3397, 09/2019, Volume 17, Issue 9, p. 500
In this paper, the chemical conjugation of marine natural products with other bioactive molecules for developing an advanced anti-cancer agent is described.... 
HALICHONDRIN-B | CHEMISTRY, MEDICINAL | GRAM-SCALE SYNTHESIS | DRUG DISCOVERY | ANTINEOPLASTIC AGENTS | marine natural products | NOMINAL DIAZONAMIDES | hybridization | CELLULAR TARGETS | anticancer agent | BISTRAMIDE-A | IEJIMALIDE-A | chimera | EUKARYOTIC TRANSLATION INITIATION | KAHALALIDE-F | chemical conjugation
Journal Article
Journal Article
CURRENT TOPICS IN MEDICINAL CHEMISTRY, ISSN 1568-0266, 04/2013, Volume 13, Issue 7, pp. 821 - 836
The structural complexity of many natural products sets them apart from common synthetic drugs, allowing them to access a biological target space that lies... 
PASSIVE MEMBRANE-PERMEABILITY | CHEMISTRY, MEDICINAL | Cell permeability | BOWMAN-BIRK INHIBITOR | Cyclic peptides | MICROCIN J25 | Lipinski's rules | CRYSTAL-STRUCTURE | Cyclosporine A | IN-VITRO | REFRACTORY PROSTATE-CANCER | KAHALALIDE-F | CYCLOSPORINE-A | ORAL BIOAVAILABILITY | Pharmacokinetics | BACTERIAL RNA-POLYMERASE
Journal Article
Cancer Letters, ISSN 0304-3835, 2010, Volume 332, Issue 2, pp. 295 - 303
Journal Article