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Journal of Organic Chemistry, ISSN 0022-3263, 09/2018, Volume 83, Issue 17, pp. 10564 - 10572
Asymmetric Michael reaction of iminoglycinate 4 to alpha,beta-unsaturated esters had been developed with >98:<2 diastereoselectivity. A reverse of... 
GLUTAMIC ACIDS | ESTER | GLYCINE | ALLOKAINIC ACID | ENANTIOSELECTIVE SYNTHESIS | HUNTINGTONS-CHOREA | CHEMISTRY, ORGANIC | ALPHA-AMINO-ACIDS | ASYMMETRIC MICHAEL ADDITION | KAINIC ACID | (+/-)-ALPHA-ALLOKAINIC ACID
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 7, pp. 727 - 730
A diversity-oriented synthetic strategy was developed for the total synthesis of kainoid amino acids, which led to the enantioselective synthesis of (-)-kainic... 
CATALYZED CYCLOISOMERIZATIONS | HUNTINGTONS-CHOREA | NEUROEXCITATORY AMINO-ACIDS | ALPHA,BETA-UNSATURATED CARBONYL-COMPOUNDS | (-)-ALPHA-KAINIC ACID | ACROMELIC ACID | KAINIC ACID | (+)-ALPHA-ALLOKAINIC ACID | CHEMISTRY, MULTIDISCIPLINARY | CLITOCYBE-ACROMELALGA | DOMOIC ACID | Amino acids | Amides | Chemical synthesis | Vinyl acetate | Isomerization
Journal Article
Chemical communications (Cambridge, England), ISSN 1359-7345, 01/2018, Volume 54, Issue 7, pp. 727 - 730
A diversity-oriented synthetic strategy was developed for the total synthesis of kainoid amino acids, which led to the enantioselective synthesis of (-)-kainic... 
Journal Article
Nature Neuroscience, ISSN 1097-6256, 10/2003, Volume 6, Issue 10, pp. 1079 - 1085
We have determined whether seizures generate an epileptogenic focus in distal structures using an in vitro preparation composed of three independent chambers... 
CA3 HIPPOCAMPAL-NEURONS | TEMPORAL-LOBE EPILEPSY | NMDA RECEPTORS | GABAERGIC INHIBITION | GABA | EXCITATORY ACTIONS | KAINIC ACID | ANTAGONISTS | NEUROSCIENCES | DEVELOPING BRAIN | NEONATAL SEIZURES | Neural Pathways - drug effects | Synaptic Transmission - physiology | Chloride Channels - drug effects | Rats, Wistar | gamma-Aminobutyric Acid - metabolism | Male | Epilepsy - physiopathology | Hippocampus - drug effects | Excitatory Postsynaptic Potentials - drug effects | Excitatory Postsynaptic Potentials - physiology | Functional Laterality - drug effects | Synaptic Transmission - drug effects | Functional Laterality - physiology | Neural Pathways - physiopathology | Disease Models, Animal | Animals, Newborn | Membrane Potentials - drug effects | Receptors, N-Methyl-D-Aspartate - drug effects | Presynaptic Terminals - drug effects | Kainic Acid - pharmacology | Rats | Excitatory Amino Acid Antagonists - pharmacology | Presynaptic Terminals - physiology | Membrane Potentials - physiology | Receptors, N-Methyl-D-Aspartate - physiology | Animals | Epilepsy - chemically induced | Glutamic Acid - metabolism | Hippocampus - physiopathology | Chloride Channels - physiology | Neurons | Epilepsy | Physiological aspects | Parahippocampal region | Research | Structure | Risk factors | gamma-Aminobutyric Acid | Receptors, N-Methyl-D-Aspartate | Functional Laterality | Cellular Biology | Neural Pathways | Synaptic Transmission | Kainic Acid | Glutamic Acid | Life Sciences | Membrane Potentials | Chloride Channels | Excitatory Postsynaptic Potentials | Presynaptic Terminals | Excitatory Amino Acid Antagonists | Hippocampus
Journal Article
Journal Article
2011, Advances in experimental medicine and biology, ISBN 9781441995568, Volume 717., xx, 131
"This volume critically examines the functional actions of the kainate type glutamate receptors (KARs). Following on from the larger body of work on the NMDA... 
Receptors, Kainic Acid | Receptors | Signal Transduction | Cerebrum | physiology | Cellular signal transduction | Kainic acid | Physiological effect | Molecular Medicine | Biomedicine general | Biomedicine
Book
Journal Article
Hearing Research, ISSN 0378-5955, 2007, Volume 227, Issue 1, pp. 19 - 27
This report summarizes recent neuropharmacological data at the IHC afferent/efferent synaptic complex: the type of Glu receptors and transporter involved and... 
AMPA | Dopamine | Lateral efferent | NMDA | Cochlea | Glutamate | Ribbon synapses | cochlea | ribbon synapses | GUINEA-PIG COCHLEA | GLUTAMATE-ASPARTATE TRANSPORTER | AUDIOLOGY & SPEECH-LANGUAGE PATHOLOGY | HIGH-AFFINITY | KAINIC ACID | EXCITOTOXIC INJURY | NEUROSCIENCES | AMINO-ACID TRANSPORTER | lateral efferent | SPIRAL GANGLION NEURONS | AFFERENT SYNAPSES | OTORHINOLARYNGOLOGY | AUDITORY-NERVE ACTIVITY | dopamine | glutamate | RAT COCHLEA | Cochlear Nerve - drug effects | Synapses - drug effects | Evoked Potentials, Auditory - drug effects | Cell Proliferation | Ear Diseases - metabolism | Humans | Ear Diseases - chemically induced | Hair Cells, Auditory, Inner - drug effects | Cochlear Nerve - metabolism | Ear Diseases - physiopathology | Regeneration | Amino Acid Transport System X-AG - metabolism | Animals | Excitatory Amino Acid Agonists - toxicity | Synapses - metabolism | Time Factors | Hair Cells, Auditory, Inner - metabolism | Neuronal Plasticity | Cell Differentiation | Glutamic Acid - metabolism | Glutamic Acid - toxicity | Ear Diseases - pathology | Receptors, AMPA - metabolism | Methyl aspartate | Peptides | Oxalic acid | Physiological aspects | GABA | Aspartate | Acetylcholine | Saturated fatty acids | Hair Cells, Inner | Excitatory Amino Acid Agonists | Cochlear Nerve | Ear Diseases | Neurons and Cognition | Amino Acid Transport System X-AG | Evoked Potentials, Auditory | Glutamic Acid | Life Sciences | Receptors, AMPA | Synapses
Journal Article
Journal of Medicinal Chemistry, ISSN 0022-2623, 07/2000, Volume 43, Issue 14, pp. 2609 - 2645
Journal Article
European Journal of Organic Chemistry, ISSN 1434-193X, 09/2012, Volume 2012, Issue 25, pp. 4661 - 4673
Journal Article