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The Journal of Immunology, ISSN 0022-1767, 06/2005, Volume 174, Issue 11, pp. 6686 - 6691
In this report, we have examined the expression of the T cell survival signals, OX40 ligand (OX40L) and CD30 ligand (CD30L) on CD4(+)CD3(-)CD11c(-)B220(-)IL-7R... 
LYMPH-NODE DEVELOPMENT | CD4 | ROR-GAMMA | FOLLICULAR DENDRITIC CELLS | MICE | T-CELL | TISSUES | IMMUNOLOGY | TNF | RECEPTOR-ALPHA | INTERLEUKIN-7 | Animals, Newborn - genetics | Receptor Activator of Nuclear Factor-kappa B | Membrane Glycoproteins - metabolism | Membrane Glycoproteins - biosynthesis | Tumor Necrosis Factors | Interleukin-7 - physiology | RANK Ligand | Receptors, OX40 | CD3 Complex - biosynthesis | Interleukin-7 - genetics | Signal Transduction - immunology | Cellular Senescence - immunology | CD3 Complex - genetics | T-Lymphocytes, Helper-Inducer - immunology | Histocompatibility Antigens Class I - biosynthesis | Receptors, Tumor Necrosis Factor - deficiency | Histocompatibility Antigens Class II - physiology | Receptors, Tumor Necrosis Factor - metabolism | Cellular Senescence - genetics | T-Lymphocytes, Helper-Inducer - metabolism | Interleukin-7 - deficiency | Carrier Proteins - biosynthesis | Mice, Inbred C57BL | Cells, Cultured | Histocompatibility Antigens Class I - physiology | CD30 Ligand | Histocompatibility Antigens Class II - biosynthesis | Mice, Transgenic | Signal Transduction - genetics | Ki-1 Antigen - metabolism | Mice, Knockout | Receptors, Interleukin-7 - physiology | Animals | Ligands | Mice | Interleukin Receptor Common gamma Subunit | Animals, Newborn - immunology | Index Medicus | Abridged Index Medicus
Journal Article
Journal Article
American Journal of Reproductive Immunology, ISSN 1046-7408, 05/2014, Volume 71, Issue 5, pp. 401 - 417
ProblemToll-like receptors (TLRs) 2 and 5 induce inflammation via the adapter proteins myeloid differentiation factor 88 (MyD88) and TNFR-associated factor 6... 
myometrium | kappa B | 2 | 5 | NF | TLR | Foetal membranes | MyD88 | Myometrium | TLR5 | NFkappa B | TLR2 | CYTOKINES | PRETERM BIRTH | FACTOR-KAPPA-B | BACTERIAL FLAGELLIN | HUMAN TERM | IMMUNOLOGY | HUMAN FETAL MEMBRANES | TOLL-LIKE RECEPTOR-2 | REPRODUCTIVE BIOLOGY | PROLABOR MEDIATORS | GENE-EXPRESSION | PARTURITION | Interleukin-8 - genetics | Myometrium - drug effects | RNA, Small Interfering - genetics | Toll-Like Receptor 2 - antagonists & inhibitors | Toll-Like Receptor 2 - genetics | Nitriles - pharmacology | Toll-Like Receptor 5 - genetics | Cyclooxygenase 2 | Humans | NF-kappa B - metabolism | Sulfones - pharmacology | Flagellin - pharmacology | Matrix Metalloproteinase 9 - metabolism | Diglycerides - pharmacology | Matrix Metalloproteinase 9 - genetics | Myometrium - metabolism | Female | Fetus | Interleukin-8 - metabolism | TNF Receptor-Associated Factor 6 - genetics | Interleukin-6 - metabolism | Toll-Like Receptor 5 - metabolism | Interleukin-6 - genetics | Signal Transduction | Tissue Culture Techniques | Gene Expression Regulation | Myeloid Differentiation Factor 88 - genetics | Toll-Like Receptor 2 - metabolism | Toll-Like Receptor 5 - antagonists & inhibitors | Pregnancy | NF-kappa B - genetics | TNF Receptor-Associated Factor 6 - metabolism | Extraembryonic Membranes - metabolism | Oligopeptides - pharmacology | Myeloid Differentiation Factor 88 - metabolism | Extraembryonic Membranes - drug effects | RNA, Small Interfering - metabolism | Index Medicus
Journal Article
Science, ISSN 0036-8075, 11/2006, Volume 314, Issue 5801, pp. 994 - 997
Journal Article
Journal of Bone and Mineral Research, ISSN 0884-0431, 2001, Volume 16, Issue 6, pp. 1004 - 1014
Fracture healing is a unique biological process regulated by a complex array of signaling molecules and proinflammatory cytokines, Recent evidence for the role... 
Fracture healing | Inflammation | Receptor activator of NF-κB ligand | Osteoprotegerin | INTERLEUKIN-1 | REGULATES OSTEOCLAST DIFFERENTIATION | INVITRO | MACROPHAGE | receptor activator of NF-kappa B ligand | fracture healing | OSTEOPOROSIS | BONE-RESORPTION | TUMOR-NECROSIS-FACTOR | REPAIR | inflammation | ENDOCRINOLOGY & METABOLISM | MICE | osteoprotegerin | CELL | RANKL protein
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2016, Volume 22, Issue 8, pp. 933 - 939
Individuals who have mutations in the breast-cancer-susceptibility gene BRCA1 (hereafter referred to as BRCA1-mutation carriers) frequently undergo... 
BRCA2 MUTATION CARRIERS | MEDICINE, RESEARCH & EXPERIMENTAL | TUMOR-DEVELOPMENT | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATION | OVARIAN-CANCER | CELL BIOLOGY | RISK-REDUCING SURGERY | STEM-CELL | MICE | DIFFERENTIAL EXPRESSION ANALYSIS | GLAND | MAMMARY EPITHELIAL-CELLS | Immunohistochemistry | Neoplasm Transplantation | RANK Ligand - metabolism | Humans | Molecular Targeted Therapy | Prophylactic Mastectomy | Stem Cells - metabolism | Breast - metabolism | Breast Neoplasms - metabolism | Denosumab - therapeutic use | Flow Cytometry | Organoids - metabolism | Female | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | Carcinogenesis - genetics | Bone Density Conservation Agents - therapeutic use | Reverse Transcriptase Polymerase Chain Reaction | Bone Density Conservation Agents - pharmacology | Breast Neoplasms - prevention & control | Carcinogenesis - drug effects | Xenograft Model Antitumor Assays | BRCA1 Protein - genetics | Animals | Breast Neoplasms - genetics | RANK Ligand - antagonists & inhibitors | Breast - drug effects | DNA Repair | Organoids - drug effects | Pilocarpine - analogs & derivatives | Stem Cells - drug effects | Heterozygote | Cell Proliferation - drug effects | Mice | Mutation | Denosumab - pharmacology | Tumor Suppressor Proteins | Care and treatment | Cytokines | BRCA mutations | Development and progression | Breast cancer | Genetic aspects | Health aspects | Ligands | Genes | Index Medicus
Journal Article
Diabetologia, ISSN 0012-186X, 12/2011, Volume 54, Issue 12, pp. 3157 - 3167
Journal Article
Journal Article
Nature Medicine, ISSN 1078-8956, 08/2012, Volume 18, Issue 8, pp. 1279 - 1285
Toll-like receptor 4 (TLR4) has a key role in innate immunity by activating an inflammatory signaling pathway. Free fatty acids (FFAs) stimulate adipose tissue... 
PATHWAYS | MEDICINE, RESEARCH & EXPERIMENTAL | ADIPOCYTES | BIOCHEMISTRY & MOLECULAR BIOLOGY | FACTOR-KAPPA-B | SATURATED FATTY-ACIDS | DIET-INDUCED OBESITY | CELL BIOLOGY | TOLL-LIKE RECEPTOR-4 | CHRONIC INFLAMMATION | EXPRESSION | ADIPOSE-TISSUE | INNATE IMMUNITY | Inflammation - chemically induced | Humans | Molecular Sequence Data | NF-kappa B - metabolism | Adipocytes - drug effects | Fatty Acids, Nonesterified - pharmacology | Adipocytes - physiology | Obesity - blood | Insulin Resistance - physiology | Base Sequence | alpha-2-HS-Glycoprotein - antagonists & inhibitors | Toll-Like Receptor 4 - antagonists & inhibitors | Binding Sites | Cytokines - genetics | Toll-Like Receptor 4 - analysis | Blood Glucose - analysis | Obesity - physiopathology | Toll-Like Receptor 4 - chemistry | 3T3-L1 Cells | alpha-2-HS-Glycoprotein - physiology | Mice, Knockout | Gene Expression Regulation - drug effects | Toll-Like Receptor 4 - physiology | Receptors, Leptin - deficiency | Diabetes Mellitus, Type 2 - blood | alpha-2-HS-Glycoprotein - toxicity | Animals | Diabetes Mellitus, Type 2 - physiopathology | alpha-2-HS-Glycoprotein - chemistry | Signal Transduction - drug effects | Galactosides - metabolism | Ligands | Mice, Obese | Signal Transduction - physiology | Mice | Mice, Inbred BALB C | Chronic Disease | Dietary Fats - toxicity | Cytokines - biosynthesis | Adipocytes - chemistry | Inflammation - physiopathology | Insulin resistance | Alpha fetoproteins | Care and treatment | Diagnosis | Health aspects | Ligands (Biochemistry) | Signal transduction | Lipids | Cytokines | Gene expression | Immune system | Index Medicus
Journal Article
Nature, ISSN 0028-0836, 11/2010, Volume 468, Issue 7320, pp. 103 - 107
RANK ligand (RANKL), a TNF-related molecule, is essential for osteoclast formation, function and survival through interaction with its receptor RANK. Mammary... 
CELL FUNCTION | OSTEOPROTEGERIN-LIGAND | MULTIDISCIPLINARY SCIENCES | MEDROXYPROGESTERONE ACETATE | RECEPTOR | HORMONE REPLACEMENT THERAPY | HUMAN BREAST-TUMORS | OSTEOCLAST DIFFERENTIATION | EXPRESSION | GLAND DEVELOPMENT | TRANSGENIC MICE | Epithelial Cells - metabolism | RANK Ligand - metabolism | Progesterone - administration & dosage | Epithelial Cells - drug effects | Humans | Progestins - adverse effects | Cell Transformation, Neoplastic - chemically induced | Mammary Neoplasms, Experimental - metabolism | Mammary Neoplasms, Experimental - genetics | Breast Neoplasms - metabolism | Lung Neoplasms - secondary | Mammary Neoplasms, Experimental - pathology | Medroxyprogesterone Acetate - adverse effects | Female | Precancerous Conditions - pathology | Receptor Activator of Nuclear Factor-kappa B - metabolism | Disease Models, Animal | 9,10-Dimethyl-1,2-benzanthracene - administration & dosage | Neoplasm Invasiveness | Mice, Inbred C57BL | Epithelial Cells - pathology | Mice, Transgenic | Progesterone - adverse effects | Mammary Neoplasms, Experimental - chemically induced | RANK Ligand - genetics | Animals | RANK Ligand - antagonists & inhibitors | Breast Neoplasms - pathology | Progestins - administration & dosage | Receptor Activator of Nuclear Factor-kappa B - genetics | Cell Proliferation - drug effects | Medroxyprogesterone Acetate - administration & dosage | Mice | Cell Transformation, Neoplastic - drug effects | Precancerous Conditions - prevention & control | Cell Transformation, Neoplastic - pathology | Mammary Tumor Virus, Mouse - genetics | Mammary Tumor Virus, Mouse - physiology | 9,10-Dimethyl-1,2-benzanthracene - adverse effects | Immunohistochemistry | Care and treatment | Usage | Physiological aspects | Breast cancer | Genetic aspects | Research | Progesterone | Tumor proteins | Health aspects | Risk factors | Proteins | Hormone replacement therapy | Rodents | Apoptosis | Index Medicus
Journal Article