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NATURE, ISSN 0028-0836, 04/2018, Volume 556, Issue 7702, pp. 501 - 501
Metabolic regulation has been recognized as a powerful principle guiding immune responses. Inflammatory macrophages undergo extensive metabolic rewiring(1)... 
APOPTOSIS | CELLS | SUCCINATE-DEHYDROGENASE | OXIDATIVE STRESS | HEME | KEY REGULATOR | OXYGENASE-1 | MULTIDISCIPLINARY SCIENCES | EXPRESSION | KAPPA-B-ZETA | PSORIASIS
Journal Article
Nature Genetics, ISSN 1061-4036, 09/2015, Volume 47, Issue 9, pp. 979 - 986
Journal Article
IMMUNITY, ISSN 1074-7613, 03/2013, Volume 38, Issue 3, pp. 450 - 460
Sjogren's syndrome (SS) is an autoimmune disease characterized by exocrinopathy that leads to dry eye and mouth. Although lymphocyte infiltration into exocrine... 
OCULAR SURFACE | PIG-A GENE | FAS LIGAND | TARGETED DISRUPTION | MOUSE MODEL | INDUCIBLE NUCLEAR-PROTEIN | ANCHORED PROTEINS | IMMUNOLOGY | SALIVARY-GLANDS | KAPPA-B-ZETA | ALPHA-FODRIN
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2015, Volume 112, Issue 43, pp. E5825 - E5833
Psoriasis is a common immune-mediated, chronic, inflammatory skin disease characterized by hyperproliferation and abnormal differentiation of keratinocytes and... 
PROTEIN | MULTIDISCIPLINARY SCIENCES | MECHANISMS | GELATINASE-ASSOCIATED LIPOCALIN | I kappa B zeta | INTERLEUKIN-17 | inflammation | psoriasis | PLAQUE PSORIASIS | IL-17 | GENE-EXPRESSION | cytokines | TNF-ALPHA | BINDING-SITES | SKIN INFLAMMATION
Journal Article
Nature Immunology, ISSN 1529-2908, 10/2010, Volume 11, Issue 10, pp. 936 - 944
Journal Article
Nature, ISSN 0028-0836, 09/2015, Volume 525, Issue 7569, pp. 389 - 393
Journal Article
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 10/2018, Volume 115, Issue 40, pp. 10088 - 10093
Proinflammatory cytokine signaling in keratinocytes plays a crucial role in the pathogenesis of psoriasis, a skin disease characterized by hyperproliferation... 
GENERALIZED PUSTULAR PSORIASIS | ANTAGONIST IL-36RA | CYTOKINES | IL-1 FAMILY | MULTIDISCIPLINARY SCIENCES | RECEPTOR | keratinocytes | INDUCTION | I kappa B zeta | IMMUNE-SYSTEM | PATHWAY | psoriasis | NFKBIZ | DISEASE | SKIN INFLAMMATION
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 10/2010, Volume 107, Issue 43, pp. 18581 - 18586
IL-33, a member of the IL-1-related cytokines, is considered to be a proallergic cytokine that is especially involved in Th2-type immune responses. Moreover,... 
T lymphocytes | Cytokines | Lungs | Endotoxins | Inflammation | Colitis | Ova | Macrophages | Potable water | Allergies | Sepsis | Interleukin-33 | Cytokine | Asthma | cytokine | colitis | MULTIDISCIPLINARY SCIENCES | TOLL-LIKE RECEPTOR | MAST-CELLS | AIRWAY INFLAMMATION | asthma | interleukin-33 | EXPERIMENTAL COLITIS | ANTIGEN-INDUCED ARTHRITIS | MICE | INTERLEUKIN-1 RECEPTOR | sepsis | KAPPA-B-ZETA | T-CELLS | Autoimmunity | Interleukin-1 - genetics | Shock, Septic - etiology | Ovalbumin - immunology | Immunity, Mucosal | Shock, Septic - immunology | Respiratory Hypersensitivity - pathology | Interleukins - genetics | Interleukins - immunology | Interleukin-1 - immunology | Colitis - immunology | Adaptive Immunity | Lipopolysaccharides - toxicity | Respiratory Hypersensitivity - etiology | Mice, Inbred C57BL | Immunity, Innate | Respiratory Hypersensitivity - immunology | Mice, Knockout | Colitis - etiology | Animals | Interleukins - deficiency | Mice | Mice, Inbred BALB C | Interleukin-1 - deficiency | Development and progression | Research | Interleukins | Properties | Immunity | Immunological memory | Memory cells | Immune response | Mucosal immunity | Epithelial cells | Hypersensitivity (delayed) | Diabetes mellitus | Hypersensitivity | Lung | Proteinase | Lymphocytes T | Experimental allergic encephalomyelitis | Hepatitis | Interleukin 1 | Respiratory tract diseases | Autoimmune diseases | Digestive tract | Injuries | Apoptosis | Biological Sciences
Journal Article
CYTOKINE, ISSN 1043-4666, 02/2016, Volume 78, pp. 20 - 21
Psoriasis is an immune-mediated chronic inflammatory skin disease with a complex etiology. The proinflammatory cytoldne IL-17A is known to play key role in the... 
Psoriasis | IL-17A | BIOCHEMISTRY & MOLECULAR BIOLOGY | Keratinocytes | Inflammation | IMMUNOLOGY | I kappa B zeta | CELL BIOLOGY
Journal Article
by Liu, SC and Wu, F and Wu, ZZ and Li, Y and Zhang, SJ and Yu, N
EXPERIMENTAL DERMATOLOGY, ISSN 0906-6705, 03/2019, Volume 28, Issue 3, pp. 233 - 239
Skin injury can trigger formation of new lesions in psoriasis (Koebner phenomenon). The mechanisms through which injury exacerbates psoriasis are unclear.... 
dsRNA | DOUBLE-STRANDED-RNA | CYTOKINES | PROTEIN | IL-17A | ANTIMICROBIAL PEPTIDE LL37 | keratinocytes | INDUCTION | IL-36-GAMMA | DEFICIENCY | DERMATOLOGY | PATHOGENESIS | psoriasis | IL-36 gamma | GENE-EXPRESSION | KAPPA-B-ZETA | Psoriasis | RNA | Analysis
Journal Article
JOURNAL OF EXPERIMENTAL MEDICINE, ISSN 0022-1007, 08/2018, Volume 215, Issue 8, pp. 2197 - 2209
NAD(P)H:quinone oxidoreductase 1 (NQO1) protects cells against oxidative stress and toxic quinones. In this study, we found a novel role of NQO1 in suppressing... 
MEDICINE, RESEARCH & EXPERIMENTAL | LIM DOMAIN PROTEIN | QUINONE OXIDOREDUCTASE-1 | TUMOR-NECROSIS-FACTOR | ARYL-HYDROCARBON RECEPTOR | SEPTIC SHOCK | DOUBLE-BLIND | ERYTHROID 2-RELATED FACTOR-2 | IMMUNOLOGY | TRANSCRIPTION FACTOR | NAD(P)H-QUINONE OXIDOREDUCTASE | KAPPA-B-ZETA
Journal Article