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Human Mutation, ISSN 1059-7794, 07/1999, Volume 13, Issue 4, pp. 301 - 310
Congenital long RT syndrome (cLQTS) is electrocardiographically characterized by a prolonged RT interval and polymorphic ventricular arrhythmias (torsade de... 
PORE REGION | KCNE1 | INHERITED CARDIAC-ARRHYTHMIA | POTASSIUM CHANNEL GENE | UMCG Approved | JERVELL | HERG | ROMANO-WARD | mutation detection | KCNQ1 | arrhythmia | KVLQT1 MUTATIONS | potassium channel | long-QT | LANGE-NIELSEN-SYNDROME | MOLECULAR-BASIS
Journal Article
American Journal of Medical Genetics, ISSN 0148-7299, 09/1999, Volume 89, Issue 3, pp. 137 - 146
Journal Article
Hearing Research, ISSN 0378-5955, 2001, Volume 153, Issue 1, pp. 132 - 145
Journal Article
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2001, Volume 134, Issue 8, pp. 1647 - 1654
Recently we and others have demonstrated a stereoselective inhibition of slowly activating human IKs (KCNQ1/MinK) and homomeric KCNQ1 potassium channels by the... 
IsK | IKs | KCNE1 | trans‐6‐cyano‐4‐(N‐ethylsulfonyl‐N‐methylamino)‐3‐hydroxy‐2,2‐dimethyl‐chromane | KCNQ1 | K‐channel, 293B | MinK | Papers | trans-6-cyano-4-(N-ethylsulfonyl-N-methylamino)-3-hydroxy-2,2-dimethyl-chromane | K-channel, 293B | I Ks
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 4/2001, Volume 98, Issue 9, pp. 5335 - 5340
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2001, Volume 33, Issue 5, pp. 873 - 882
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 2001, Volume 134, Issue 8, pp. 1647 - 1654
Journal Article
2001, Volume 6, Issue 2, 7
The late detection of cardiotoxic side effects, such as QT prolongation, induced by compounds of pharmacological interest can dramatically impede drug... 
KCNE1 | Cardiac actionpotential | HERG | KCNE2 | KCNQ1 | Electrophysiology fluorescence | HTS | QT-pralongation | Voltage-sensitive dye | IN-VITRO | ANTIHISTAMINES | POTASSIUM CHANNELS | BIOCHEMISTRY & MOLECULAR BIOLOGY | ASTEMIZOLE | CARDIAC ION CHANNELS | PHARMACOLOGY & PHARMACY | MECHANISMS | ARRHYTHMIA | CELL-LINE | RECTIFIER
Book Review
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 7/2001, Volume 98, Issue 15, pp. 8792 - 8797
Journal Article