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Diabetic Medicine, ISSN 0742-3071, 09/2018, Volume 35, Issue 9, pp. 1291 - 1296
Background Permanent neonatal diabetes caused by mutations in the KCNJ11 gene may be managed with high‐dose sulfonylureas. Complete transfer to sulfonylureas... 
KIR6.2 | THERAPY | MUTATIONS | KCNJ11 | ENDOCRINOLOGY & METABOLISM | Infants (Newborn) | Diabetics | Hyperglycemia | Peptides | Blood sugar monitoring | Blood sugar | Insulin | Diabetes therapy | Neonates | Diabetes mellitus | Tolbutamide | KCNJ11 gene | Hypoglycemia | Oocytes | Sulfonylurea | Titration | Diabetes | Mutation | Glibenclamide
Journal Article
European Journal of Human Genetics, ISSN 1018-4813, 2019, Volume 27, Issue 6, pp. 989 - 993
A 22-year-old man was referred for continuation of diabetes mellitus treatment. He was first diagnosed with diabetes mellitus 2 months after birth, when he... 
KIR6.2 | INSULIN | GENE | SULFONYLUREAS | ABCC8 | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENETICS & HEREDITY | MELLITUS | KCNJ11 MUTATIONS | ACTIVATING MUTATIONS | GLIBENCLAMIDE | SUBUNIT | Neonates | Potassium channels (inwardly-rectifying) | Diabetes mellitus | Epilepsy | KCNJ11 gene | Hypoglycemia | Insulin | Genetic screening | Ketoacidosis | Titration | Diabetes | Diagnosis | Health risk assessment | Glibenclamide | Hypertrophy
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2009, Volume 119, Issue 1, pp. 80 - 90
Neonatal diabetes is a rare monogenic form of diabetes that usually presents within the first six months of life. It is commonly caused by gain-of-function... 
MEDICINE, RESEARCH & EXPERIMENTAL | HYPERGLYCEMIA | THERAPY | PROTEIN | ISLETS | KCNJ11 | INSULIN-SECRETION | RECEPTOR | MICE | PROMOTER | SENSORS
Journal Article
PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, ISSN 0031-6768, 07/2010, Volume 460, Issue 2, pp. 295 - 306
Journal Article
Journal of Pediatric Endocrinology and Metabolism, ISSN 0334-018X, 08/2013, Volume 26, Issue 7-8, pp. 743 - 746
Journal Article
NATURE REVIEWS ENDOCRINOLOGY, ISSN 1759-5029, 11/2013, Volume 9, Issue 11, pp. 660 - 669
ATP-sensitive potassium channels (K-ATP channels) link cell metabolism to electrical activity by controlling the cell membrane potential. They participate in... 
NEONATAL DIABETES-MELLITUS | SENSITIVE POTASSIUM-CHANNEL | PERSISTENT HYPERINSULINEMIC HYPOGLYCEMIA | INSULIN-SECRETION | ENDOCRINOLOGY & METABOLISM | SUBUNITS KIR6.2 KCNJ11 | PANCREATIC BETA-CELLS | GATED ION CHANNELS | MOUSE ALPHA-CELLS | FOCAL CONGENITAL HYPERINSULINISM | STIMULATES GLUCAGON-RELEASE
Journal Article
Journal of Pediatric Endocrinology and Metabolism, ISSN 0334-018X, 05/2013, Volume 26, Issue 5-6, pp. 591 - 594
Journal Article
Current Diabetes Reports, ISSN 1534-4827, 8/2019, Volume 19, Issue 8, pp. 1 - 9
Journal Article
JOURNAL OF PHYSIOLOGY-LONDON, ISSN 0022-3751, 09/2010, Volume 588, Issue 17, pp. 3201 - 3209
ATP-sensitive potassium (K-ATP) channels are critical for the maintenance of glucose homeostasis. They are essential for glucose-stimulated insulin secretion... 
SENSITIVE POTASSIUM CHANNELS | CONGENITAL HYPERINSULINISM | INSULIN | SKELETAL-MUSCLE | NEONATAL DIABETES-MELLITUS | DEND SYNDROME | PHYSIOLOGY | SULFONYLUREA THERAPY | SUBUNITS KIR6.2 KCNJ11 | PANCREATIC BETA-CELLS | NEUROSCIENCES | ACTIVATING MUTATIONS
Journal Article
Journal Article
International Journal of Endocrinology and Metabolism, ISSN 1726-913X, 2016, Volume 14, Issue 4, p. e37311
Congenital hyperinsulinism is a rare inherited disease caused by mutations in genes responsible for β-cell's function in glucose hemostasis leading to profound... 
KCNJ11 | Congenital hyperinsulinism | HADH | ABCC8
Journal Article