X
Search Filters
Format Format
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (594) 594
animals (555) 555
index medicus (481) 481
kcnq1 potassium channel - genetics (384) 384
kcnq1 potassium channel - metabolism (346) 346
female (270) 270
kcnq1 (257) 257
male (242) 242
potassium channels (228) 228
potassium channels, voltage-gated - metabolism (195) 195
kcnq1 potassium channel (193) 193
mutation (182) 182
kcnq potassium channels (176) 176
mice (173) 173
potassium channels, voltage-gated - genetics (159) 159
potassium channel (153) 153
potassium channels, voltage-gated (148) 148
long qt syndrome (145) 145
biochemistry & molecular biology (137) 137
proteins (135) 135
patch-clamp techniques (132) 132
physiology (132) 132
cardiac & cardiovascular systems (122) 122
long qt syndrome - genetics (122) 122
potassium channels - metabolism (113) 113
genetic aspects (112) 112
adult (110) 110
potassium channels - genetics (110) 110
article (106) 106
middle aged (106) 106
cell biology (100) 100
kvlqt1 (99) 99
research (99) 99
long-qt syndrome (98) 98
i-ks (96) 96
cho cells (92) 92
potassium - metabolism (92) 92
kcnq1 protein (91) 91
molecular sequence data (90) 90
cricetinae (89) 89
rats (89) 89
endocrine system diseases (87) 87
amino acid sequence (86) 86
xenopus laevis (86) 86
diabetes mellitus, type 2 - genetics (85) 85
expression (85) 85
electrophysiology (83) 83
genotype (81) 81
risk factors (81) 81
type 2 diabetes (81) 81
gene (80) 80
ion channels (80) 80
multidisciplinary sciences (79) 79
mutations (77) 77
transfection (75) 75
erg1 potassium channel (71) 71
genes (71) 71
genetics (71) 71
gene expression (70) 70
arrhythmia (69) 69
heart (69) 69
kcnq1 potassium channel - chemistry (69) 69
long qt syndrome - metabolism (69) 69
potassium (69) 69
genetic predisposition to disease (68) 68
kcne1 (68) 68
klqt1 (67) 67
oocytes - metabolism (67) 67
phenotype (67) 67
endocrinology & metabolism (66) 66
myocardium - metabolism (66) 66
research article (65) 65
cells, cultured (64) 64
analysis (62) 62
k+ channel (62) 62
medicine (62) 62
cell line (61) 61
pharmacology & pharmacy (61) 61
cricetulus (60) 60
diabetes (60) 60
kinetics (60) 60
physiological aspects (60) 60
polymorphism, single nucleotide (60) 60
urogenital system (59) 59
genetics & heredity (57) 57
aged (56) 56
electrocardiography (56) 56
xenopus (56) 56
action potentials (55) 55
alleles (55) 55
genomes (55) 55
myocytes, cardiac - metabolism (55) 55
potassium channel blockers - pharmacology (55) 55
biophysics (53) 53
science (53) 53
biology (51) 51
membrane potentials (51) 51
susceptibility (51) 51
herg (50) 50
diabetes mellitus (49) 49
more...
Language Language
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Cardiovascular Research, ISSN 0008-6363, 09/2012, Volume 95, Issue 4, pp. 419 - 429
Long QT syndrome (LQTS) is an inheritable and life-threatening disease; however, it is often difficult to determine disease characteristics in sporadic cases... 
Long QT syndrome | Cardiomyocytes | Personalized medicine | Drug examination | iPS cells | CARDIAC & CARDIOVASCULAR SYSTEMS | MODELS | DEATH | LONG-QT SYNDROME | REPOLARIZATION RESERVE | I-KS | KCNQ1 Potassium Channel - genetics | Intermediate-Conductance Calcium-Activated Potassium Channels - genetics | Coculture Techniques | Humans | KCNQ1 Potassium Channel - metabolism | Romano-Ward Syndrome - pathology | Male | Intermediate-Conductance Calcium-Activated Potassium Channels - metabolism | Cellular Reprogramming | Teratoma - metabolism | Action Potentials | Embryoid Bodies - metabolism | Transfection | Potassium Channels, Voltage-Gated - metabolism | Time Factors | Gene Expression Regulation, Developmental | HEK293 Cells | Intermediate-Conductance Calcium-Activated Potassium Channels - antagonists & inhibitors | KCNQ1 Potassium Channel - antagonists & inhibitors | Cell Differentiation | Romano-Ward Syndrome - genetics | Potassium Channel Blockers - pharmacology | Induced Pluripotent Stem Cells - metabolism | Potassium Channels, Voltage-Gated - genetics | Induced Pluripotent Stem Cells - pathology | Genetic Predisposition to Disease | Induced Pluripotent Stem Cells - drug effects | Romano-Ward Syndrome - diagnosis | Induced Pluripotent Stem Cells - transplantation | Embryoid Bodies - pathology | Potassium Channels, Voltage-Gated - antagonists & inhibitors | Myocytes, Cardiac - pathology | Myocytes, Cardiac - transplantation | Patch-Clamp Techniques | Phenotype | Teratoma - pathology | Animals | Myocytes, Cardiac - drug effects | Adolescent | Fluorescent Antibody Technique | Romano-Ward Syndrome - metabolism | Myocytes, Cardiac - metabolism | Mice
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 8/2013, Volume 110, Issue 32, pp. 13180 - 13185
Voltage-gated ion channels generate dynamic ionic currents that are vital to the physiological functions of many tissues. These proteins contain separate... 
Steady state current | Electric potential | Lipids | Ion channels | Sensors | Potassium channels | Electric current | Genetic mutation | Oocytes | Phosphatidylinositols | KCNQ | Phosphoinositide | Voltage channel | Channelopathy | Electromechanical coupling | ELECTROSTATIC INTERACTIONS | PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE | channelopathy | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | SYNDROME GENES | LONG-QT SYNDROME | GATED SODIUM-CHANNEL | I-KS | phosphoinositide | DEPENDENT K+ CHANNEL | electromechanical coupling | STRUCTURAL BASIS | voltage channel | POTASSIUM CHANNEL | Membrane Potentials - genetics | KCNQ1 Potassium Channel - genetics | Humans | KCNQ1 Potassium Channel - metabolism | Molecular Sequence Data | Phosphatidylinositol 4,5-Diphosphate - metabolism | Ion Channel Gating - physiology | KCNQ1 Potassium Channel - chemistry | Female | Phosphatidylinositol 4,5-Diphosphate - chemistry | Protein Structure, Tertiary | Amino Acid Sequence | Oocytes - metabolism | Xenopus laevis | Models, Molecular | Binding Sites - genetics | Membrane Potentials - physiology | Blotting, Western | Sequence Homology, Amino Acid | Patch-Clamp Techniques | Algorithms | Animals | Ion Channel Gating - genetics | Oocytes - physiology | Models, Biological | Protein Binding | Mutation | Physiological aspects | Electrophysiology | Lipid metabolism | Research | Biological Sciences
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2012, Volume 109, Issue 18, pp. 7103 - 7108
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 07/2014, Volume 34, Issue 7, pp. 1522 - 1530
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2018, Volume 13, Issue 8, p. e0201092
We screened a library of botanical compounds purified from plants of Vietnam for modulators of the activity of a two-pore domain K+ channel, TREK-1, and we... 
RILUZOLE | INHIBITION | ANXIETY | MULTIDISCIPLINARY SCIENCES | COUMARIN | PLANTS | REGULATIONS | STRESS | K+ CHANNELS | BEHAVIORS | POTASSIUM CHANNEL | Humans | Ether-A-Go-Go Potassium Channels - metabolism | Kv1.4 Potassium Channel - metabolism | Male | Anxiety - drug therapy | Brain - metabolism | Dose-Response Relationship, Drug | Kv1.4 Potassium Channel - antagonists & inhibitors | Depression - drug therapy | Depression - metabolism | Neurotransmitter Agents - pharmacology | HEK293 Cells | Potassium Channels, Inwardly Rectifying - antagonists & inhibitors | Antidepressive Agents - pharmacology | Drug Evaluation, Preclinical | Anxiety - metabolism | Potassium Channels, Tandem Pore Domain - metabolism | Nerve Tissue Proteins - antagonists & inhibitors | Anti-Anxiety Agents - pharmacology | Potassium Channels, Tandem Pore Domain - agonists | Mice, Inbred ICR | Brain - drug effects | Ether-A-Go-Go Potassium Channels - antagonists & inhibitors | Nerve Tissue Proteins - metabolism | Umbelliferones - pharmacology | Animals | Potassium Channels, Tandem Pore Domain - antagonists & inhibitors | Amlodipine - pharmacology | Phytochemicals - pharmacology | Potassium Channels, Inwardly Rectifying - metabolism | Care and treatment | Depression, Mental | Analysis | Dosage and administration | Research | Potassium channels | T cells | Antianxiety agents | Neurosciences | Amygdala | Mental disorders | Mental depression | Paraventricular nucleus | Nuclei | Channels | Modulators | Antidepressants | Dorsal raphe nucleus | Rodents | Rectifiers | Raphe nuclei | Physiology | Life sciences | Anxiety | Potassium channels (voltage-gated) | Behavior | Inhibition | c-Fos protein | Serotonin | Potassium channels (inwardly-rectifying) | Immunomodulation | Septum | Chemistry | Mood | Anxieties | Natural products | Psychopharmacology | KCNQ1 protein | Immunoreactivity | Potassium
Journal Article
Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN 0028-1298, 10/2016, Volume 389, Issue 10, pp. 1133 - 1137
Journal Article
Journal Article
Journal Article