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Diabetologia, ISSN 0012-186X, 5/2011, Volume 54, Issue 5, pp. 1052 - 1056
By combining multiple genome-wide association (GWA) studies and comprehensive replication efforts, 12 novel type 2 diabetes associated loci have recently been... 
Type 2 diabetes | Medicine & Public Health | Human Physiology | Genetic epidemiology | Metabolic Diseases | Association study | Internal Medicine | Beta cell function | TOLERANCE | ENDOCRINOLOGY & METABOLISM | SUSCEPTIBILITY LOCI | RESISTANCE | SENSITIVITY | BETA-CELL FUNCTION | KCNQ1 Potassium Channel - genetics | Hepatocyte Nuclear Factor 1-alpha - genetics | Diabetes Mellitus, Type 2 - genetics | Humans | Middle Aged | Male | Diabetes Mellitus, Type 2 - metabolism | Molecular Epidemiology - methods | Diabetes Mellitus, Type 2 - epidemiology | Heat-Shock Proteins - genetics | Insulin-Secreting Cells - metabolism | Dual-Specificity Phosphatases - genetics | HMGA2 Protein - genetics | Cell Cycle Proteins - genetics | Adult | Female | Nuclear Proteins - genetics | Insulin Secretion | Genome-Wide Association Study | Glucose Tolerance Test | Genotype | Glucose - pharmacology | Transcription Factors - genetics | DNA-Binding Proteins - genetics | Mitogen-Activated Protein Kinase Phosphatases - genetics | Carrier Proteins - genetics | Insulin - metabolism | Insulin-Secreting Cells - drug effects | Adaptor Proteins, Signal Transducing - genetics | Alleles | Sp Transcription Factors - genetics | GTPase-Activating Proteins - genetics | Pancreatic beta cells | Chromosomal proteins | Genomics | Insulin resistance | Universities and colleges | Glucose | Glucose tolerance tests | Insulin | Risk factors | Dextrose | Glucose metabolism | Resveratrol
Journal Article
Journal Article
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2007, Volume 104, Issue 52, pp. 20990 - 20995
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 04/2017, Volume 1859, Issue 4, pp. 586 - 597
Journal Article
American Journal of Physiology - Cell Physiology, ISSN 0363-6143, 2015, Volume 309, Issue 10, pp. 693 - 706
Journal Article
Molecular Metabolism, ISSN 2212-8778, 2013, Volume 2, Issue 4, pp. 337 - 347
Abstract Obesity is characterized as an excess accumulation of body fat resulting from a positive energy balance. It is the major risk factor for type 2... 
Endocrinology & Metabolism | Type 2 diabetes | Epigenetics | Obesity | GWAS | Positional cloning | OBESITY GENE | DNA METHYLATION | FTO GENE | HIGH-FAT DIET | GLUCOSE-HOMEOSTASIS | IDENTIFIES COMMON | ENDOCRINOLOGY & METABOLISM | Type 2 diabetes: GWAS | INVERSE AGONIST | BODY-MASS INDEX | FRAMESHIFT MUTATION | MELANOCORTIN-4 RECEPTOR
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2017, Volume 12, Issue 10, p. e0186293
The slow delayed-rectifier potassium current (I-Ks) is crucial for human cardiac action potential repolarization. The formation of I-Ks requires co-assembly of... 
INWARD RECTIFIER | MULTIDISCIPLINARY SCIENCES | GATED POTASSIUM CHANNELS | LONG-QT-SYNDROME | RECEPTOR-MEDIATED INHIBITION | ION CHANNELS | I-KS | PHOSPHOINOSITIDE 3-KINASE | CELL REGULATION | K+ CHANNELS | LIVING CELLS | Cricetinae | Cricetulus | Golgi Apparatus - drug effects | Humans | KCNQ1 Potassium Channel - metabolism | Endoplasmic Reticulum - metabolism | Protein Transport - drug effects | Mutation - genetics | Sirolimus - pharmacology | Phosphatidylinositol 4,5-Diphosphate - metabolism | Animals | Potassium Channels, Voltage-Gated - metabolism | Endoplasmic Reticulum - drug effects | Protein Binding - drug effects | HEK293 Cells | Golgi Apparatus - metabolism | Cell Membrane - metabolism | Cell Membrane - drug effects | Genes, Reporter | Protein Multimerization - drug effects | CHO Cells | Ion Channel Gating - drug effects | Physiological aspects | Phosphoinositides | Genetic aspects | Potassium channels | Research | Gene expression | Heart | Phosphates | Residues | Trafficking | Action potential | Phosphatidylinositol 4,5-diphosphate | Kinases | Phosphatase | Cell surface | Proteins | Rodents | Long QT syndrome | Physiology | Potassium channels (voltage-gated) | Protein transport | Dimerization | Heart diseases | Potassium channels (inwardly-rectifying) | C-Terminus | Dentistry | Golgi apparatus | Depletion | KCNQ1 protein | Mutation | Endoplasmic reticulum | Potassium | Binding sites
Journal Article