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The Journal of neuroscience, ISSN 0270-6474, 01/2017, Volume 37, Issue 3, pp. 576 - 586
KCNQ3 | Sodium channels | Potassium channels | Epilepsy | KCNQ2 | Neocortex - physiology | Humans | Mice, Transgenic | Epilepsy - physiopathology | KCNQ2 Potassium Channel - deficiency | Mice, Knockout | Action Potentials - physiology | Animals | Pyramidal Cells - physiology | HEK293 Cells | KCNQ2 Potassium Channel - genetics | Epilepsy - genetics | KCNQ2 Potassium Channel - physiology | Mice | Index Medicus | epilepsy | s | sodium channels | potassium channels
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Neurobiology of disease, ISSN 0969-9961, 10/2018, Volume 118, pp. 76 - 93
7 channels | Epileptic encephalopathy | Phosphoinositide | Surface expression | Excitability | Kcnq2 | Mutation | Current | Calmodulin | Epilepsy, Generalized - genetics | Phosphatidylinositols - genetics | Amino Acid Sequence | Brain Diseases - metabolism | Neurons - pathology | Gene Expression | Protein Structure, Secondary | Humans | Brain Diseases - genetics | Axons - metabolism | Rats | Epilepsy, Generalized - pathology | Phosphatidylinositols - biosynthesis | KCNQ2 Potassium Channel - biosynthesis | KCNQ2 Potassium Channel - chemistry | Animals | Brain Diseases - pathology | Epilepsy, Generalized - metabolism | Axons - pathology | HEK293 Cells | KCNQ2 Potassium Channel - genetics | Neurons - metabolism
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Dominant‐negative effects of KCNQ2 mutations are associated with epileptic encephalopathy
Annals of neurology, ISSN 0364-5134, 03/2014, Volume 75, Issue 3, pp. 382 - 394
Neurosciences | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Xenopus | Genetic Predisposition to Disease - genetics | Membrane Potentials - genetics | Potassium Channels, Voltage-Gated - physiology | Epilepsy, Benign Neonatal - physiopathology | Humans | KCNQ2 Potassium Channel - drug effects | Mutation, Missense | Oocytes | Animals | Epilepsy, Benign Neonatal - genetics | KCNQ2 Potassium Channel - genetics | Potassium Channels, Voltage-Gated - drug effects | Phenylenediamines - pharmacology | KCNQ2 Potassium Channel - physiology | Carbamates - pharmacology | Potassium Channels, Voltage-Gated - genetics | Potassium | Mutation | Index Medicus
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Nature communications, ISSN 2041-1723, 11/2015, Volume 6, Issue 1, pp. 8815 - 8815
Science & Technology - Other Topics | Multidisciplinary Sciences | Science & Technology | Kv1.1 Potassium Channel - genetics | Kv1.1 Potassium Channel - chemistry | Kv1.1 Potassium Channel - metabolism | Neurons - chemistry | Axons - metabolism | Axons - chemistry | Protein Transport | KCNQ2 Potassium Channel - chemistry | Animals | KCNQ2 Potassium Channel - metabolism | Neuronal Plasticity | Chickens | KCNQ2 Potassium Channel - genetics | Neurons - metabolism | Kinetics | Resistance | Homeostasis | Cochlea | Neurons | Channels | Elongation | Index Medicus
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Neurobiology of disease, ISSN 0969-9961, 2015, Volume 80, pp. 80 - 92
Neurology | Early epileptic encephalopathy | p.A294G mutation | Kv7 channels | Subcellular channel expression | p.A294V mutation | M-current | P.A294V mutation | P.A294G mutation | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Cricetulus | Brain - physiopathology | Humans | Cells, Cultured | Epilepsy - physiopathology | Epilepsy - diagnosis | Brain - metabolism | Hippocampus - metabolism | Phenotype | Animals | KCNQ2 Potassium Channel - metabolism | KCNQ2 Potassium Channel - genetics | Epilepsy - genetics | KCNQ2 Potassium Channel - physiology | Neurons - metabolism | Mutation | CHO Cells | Encephalopathy | Epilepsy | Genetic aspects | Index Medicus | Life Sciences | Genetics
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Homomeric Kv7.2 current suppression is a common feature in KCNQ2 epileptic encephalopathy
Epilepsia (Copenhagen), ISSN 0013-9580, 01/2019, Volume 60, Issue 1, pp. 139 - 148
epilepsy | PIP 2 | M‐current | early infantile epileptic encephalopathies | KCNQ2 | PIP | M-current | Clinical Neurology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Epilepsy, Generalized - genetics | Amino Acid Sequence | Protein Structure, Secondary | Brain Diseases - diagnosis | Humans | Brain Diseases - genetics | Child, Preschool | Infant | Male | KCNQ2 Potassium Channel - chemistry | Pedigree | KCNQ2 Potassium Channel - genetics | Female | Epilepsy, Generalized - diagnosis | Child | Phosphatidylinositol | Phenotypes | Epilepsy | Encephalopathy | Potassium channels (voltage-gated) | Mutation | Phosphatidylinositol 4,5-diphosphate | KCNQ2 protein | Genotypes | Index Medicus
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Pain (Amsterdam), ISSN 0304-3959, 03/2013, Volume 154, Issue 3, pp. 434 - 448
KCNQ channel | M current | Retigabine | Hyperexcitability | Dorsal root ganglion | Bone cancer pain | XE-991 | Neurosciences | Clinical Neurology | Anesthesiology | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Biological and medical sciences | Medical sciences | Diseases of the osteoarticular system | Tumors of striated muscle and skeleton | Neoplasm Transplantation | Phenylenediamines - therapeutic use | Nociception - physiology | Bone Neoplasms - secondary | Stress, Mechanical | Ganglia, Spinal - physiopathology | KCNQ3 Potassium Channel - physiology | Bone Neoplasms - pathology | KCNQ2 Potassium Channel - antagonists & inhibitors | Synaptic Transmission | Tibia - pathology | Sensory Receptor Cells - physiology | Bone Neoplasms - physiopathology | Mammary Neoplasms, Experimental - pathology | Pain - etiology | Female | KCNQ2 Potassium Channel - physiology | Sensory Receptor Cells - metabolism | Carcinoma - pathology | Potassium Channel Blockers - pharmacology | Carbamates - pharmacology | Carcinoma - secondary | KCNQ3 Potassium Channel - antagonists & inhibitors | Hot Temperature - adverse effects | Down-Regulation | Rats | KCNQ3 Potassium Channel - genetics | KCNQ2 Potassium Channel - biosynthesis | Rats, Sprague-Dawley | Anthracenes - pharmacology | Carcinoma - physiopathology | Hyperalgesia - physiopathology | KCNQ3 Potassium Channel - biosynthesis | Patch-Clamp Techniques | Animals | KCNQ2 Potassium Channel - genetics | Hyperalgesia - etiology | Phenylenediamines - pharmacology | Carbamates - therapeutic use | Cancer pain | Bone cancer | Potassium channels | Ganglion | Neurons | Index Medicus
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European journal of pharmacology, ISSN 0014-2999, 09/2019, Volume 858, p. 172474
Life Sciences & Biomedicine | Pharmacology & Pharmacy | Science & Technology | KCNQ3 Potassium Channel - antagonists & inhibitors | KCNQ3 Potassium Channel - metabolism | Humans | Rats | Neurons - cytology | Receptor, Muscarinic M1 - antagonists & inhibitors | KCNQ3 Potassium Channel - genetics | KCNQ2 Potassium Channel - antagonists & inhibitors | KCNQ2 Potassium Channel - agonists | Gene Expression Regulation - drug effects | Receptor, Muscarinic M1 - agonists | Animals | KCNQ2 Potassium Channel - metabolism | Muscarinic Antagonists - pharmacology | KCNQ2 Potassium Channel - genetics | Neurons - metabolism | KCNQ3 Potassium Channel - agonists | Induced Pluripotent Stem Cells - cytology | Neurons - drug effects | Potassium Channel Blockers - pharmacology | Receptor, Muscarinic M1 - metabolism | Electrophysiological Phenomena - drug effects
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The Journal of neuroscience, ISSN 0270-6474, 2015, Volume 35, Issue 23, pp. 8829 - 8842
Epilepsy | KCNQ channels | Tinnitus | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Membrane Potentials - genetics | Phenylenediamines - therapeutic use | Humans | Male | Epilepsy - etiology | Tinnitus - prevention & control | Carbamates - chemistry | KCNQ2 Potassium Channel - agonists | KCNQ2 Potassium Channel - metabolism | HEK293 Cells | Tinnitus - etiology | Epilepsy - genetics | Female | Disease Models, Animal | Animals, Newborn | Membrane Potentials - drug effects | Anticonvulsants - therapeutic use | Rats | Transcription Factors - genetics | Mutation - genetics | Rats, Sprague-Dawley | Homeodomain Proteins - genetics | Mice, Inbred ICR | Mice, Knockout | Animals | Anticonvulsants - chemistry | Evoked Potentials, Auditory, Brain Stem - genetics | KCNQ2 Potassium Channel - genetics | Epilepsy - drug therapy | Mice | Carbamates - therapeutic use | In Vitro Techniques | Phenylenediamines - chemistry | KCNQ Potassium Channels - genetics | Index Medicus | epilepsy | tinnitus
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Bio-medical materials and engineering, ISSN 0959-2989, 2017, Volume 28, Issue 1, pp. S243 - S253
temperature | benign familial neonatal convulsions | febrile seizures | ion channels | KCNQ2 | KCNQ2 Potassium Channel - analysis | Point Mutation | Temperature | Endoplasmic Reticulum - genetics | KCNQ2 Potassium Channel - metabolism | Humans | HEK293 Cells | KCNQ2 Potassium Channel - genetics | Endoplasmic Reticulum - metabolism | Hot Temperature | Protein Transport | Temperature dependence | Excitability | Fluorescence | High temperature | Retention | Western blotting | Mutants | Elevation | Temperature effects | Ion channels | Potassium channels (voltage-gated) | Endoplasmic reticulum | Potassium | Fluorescence microscopy | KCNQ2 protein | Seizures | Index Medicus
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The Journal of neuroscience, ISSN 0270-6474, 2014, Volume 34, Issue 15, pp. 5311 - 5321
M current | KCNQ3 | BFNC | Epilepsy | KCNQ2 | Neurosciences | Neurosciences & Neurology | Life Sciences & Biomedicine | Science & Technology | Pyramidal Cells - metabolism | KCNQ3 Potassium Channel - metabolism | Mice, Inbred C57BL | Epilepsy - metabolism | Epilepsy - physiopathology | KCNQ3 Potassium Channel - genetics | Nerve Tissue Proteins - genetics | Action Potentials | Nerve Tissue Proteins - metabolism | Animals | KCNQ2 Potassium Channel - metabolism | Gene Deletion | Pyramidal Cells - physiology | KCNQ2 Potassium Channel - genetics | Epilepsy - genetics | Mice | Index Medicus | epilepsy
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